UniProtKB - Q73EA6 (FENR1_BACC1)
Protein
Ferredoxin--NADP reductase 1
Gene
BCE_0452
Organism
Bacillus cereus (strain ATCC 10987 / NRS 248)
Status
Functioni
Catalytic activityi
- H+ + NADP+ + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]UniRule annotationEC:1.18.1.2UniRule annotation
Cofactori
FADUniRule annotationNote: Binds 1 FAD per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 36 | FADUniRule annotation | 1 | |
Binding sitei | 44 | FADUniRule annotation | 1 | |
Binding sitei | 48 | FADUniRule annotation | 1 | |
Binding sitei | 88 | FAD; via amide nitrogen and carbonyl oxygenUniRule annotation | 1 | |
Binding sitei | 123 | FAD; via amide nitrogenUniRule annotation | 1 | |
Binding sitei | 290 | FADUniRule annotation | 1 | |
Binding sitei | 331 | FADUniRule annotation | 1 |
GO - Molecular functioni
- ferredoxin-NADP+ reductase activity Source: UniProtKB-UniRule
- flavin adenine dinucleotide binding Source: UniProtKB-UniRule
- NADP binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | Oxidoreductase |
Ligand | FAD, Flavoprotein, NADP |
Enzyme and pathway databases
BioCyci | BCER222523:G1G0J-497-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Ferredoxin--NADP reductase 1UniRule annotation (EC:1.18.1.2UniRule annotation)Short name: FNR 1UniRule annotation Short name: Fd-NADP(+) reductase 1UniRule annotation |
Gene namesi | Ordered Locus Names:BCE_0452 |
Organismi | Bacillus cereus (strain ATCC 10987 / NRS 248) |
Taxonomic identifieri | 222523 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000364788 | 1 – 349 | Ferredoxin--NADP reductase 1Add BLAST | 349 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the ferredoxin--NADP reductase type 2 family.UniRule annotation
Phylogenomic databases
HOGENOMi | CLU_031864_5_5_9 |
OMAi | LEQCAPF |
Family and domain databases
Gene3Di | 3.50.50.60, 2 hits |
HAMAPi | MF_01685, FENR2, 1 hit |
InterProi | View protein in InterPro IPR036188, FAD/NAD-bd_sf IPR023753, FAD/NAD-binding_dom IPR022890, Fd--NADP_Rdtase_type_2 |
Pfami | View protein in Pfam PF07992, Pyr_redox_2, 1 hit |
SUPFAMi | SSF51905, SSF51905, 1 hit |
i Sequence
Sequence statusi: Complete.
Q73EA6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNREELFDVT VIGGGPAGLY SAFYSGLREM KTKIIEFQPQ LGGKIHVYPE
60 70 80 90 100
KMIWDVGGLL PVTGDKLIEQ LVQQGLTFQP EVVLNTKVES IIRNKDGTFT
110 120 130 140 150
LKANDGKEHF SKTVIVATGS GILKPQKLSI EGAERFEVSN LNYTVKSLKR
160 170 180 190 200
FKDKTIIISG GGNSAVDWAN ELEPIAKKVY VTYRKEELSG HEAQVKQLLN
210 220 230 240 250
SSAECFFHTS ITKLIAGDSH EAIEYVELTN HETGEVSHLL IDEVIINHGY
260 270 280 290 300
ERDITLLENS ELDVAIIDNF YIAGNANSES SVDGLYAAGD ILKHEGKLHL
310 320 330 340
IAGAFQDAGN AVNKAKQFIQ PDASEYGMVS SHNEVFKKRN RELIKQMMK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017194 Genomic DNA Translation: AAS39388.1 |
RefSeqi | WP_001078292.1, NC_003909.8 |
Genome annotation databases
EnsemblBacteriai | AAS39388; AAS39388; BCE_0452 |
GeneIDi | 59159195 |
KEGGi | bca:BCE_0452 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017194 Genomic DNA Translation: AAS39388.1 |
RefSeqi | WP_001078292.1, NC_003909.8 |
3D structure databases
SMRi | Q73EA6 |
ModBasei | Search... |
Genome annotation databases
EnsemblBacteriai | AAS39388; AAS39388; BCE_0452 |
GeneIDi | 59159195 |
KEGGi | bca:BCE_0452 |
Phylogenomic databases
HOGENOMi | CLU_031864_5_5_9 |
OMAi | LEQCAPF |
Enzyme and pathway databases
BioCyci | BCER222523:G1G0J-497-MONOMER |
Family and domain databases
Gene3Di | 3.50.50.60, 2 hits |
HAMAPi | MF_01685, FENR2, 1 hit |
InterProi | View protein in InterPro IPR036188, FAD/NAD-bd_sf IPR023753, FAD/NAD-binding_dom IPR022890, Fd--NADP_Rdtase_type_2 |
Pfami | View protein in Pfam PF07992, Pyr_redox_2, 1 hit |
SUPFAMi | SSF51905, SSF51905, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | FENR1_BACC1 | |
Accessioni | Q73EA6Primary (citable) accession number: Q73EA6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 3, 2009 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |