UniProtKB - Q72I04 (RL3_THET2)
Protein
50S ribosomal protein L3
Gene
rplC
Organism
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Status
Functioni
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.UniRule annotation
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: 50S ribosomal protein L3UniRule annotation |
Gene namesi | Name:rplCUniRule annotation Ordered Locus Names:TT_C1328 |
Organismi | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) |
Taxonomic identifieri | 262724 [NCBI] |
Taxonomic lineagei | Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000241428 | 1 – 206 | 50S ribosomal protein L3Add BLAST | 206 |
Interactioni
Subunit structurei
Part of the 50S ribosomal subunit.
Forms a cluster with proteins L14 and L19.
UniRule annotationProtein-protein interaction databases
STRINGi | 262724.TT_C1328 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q72I04 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q72I04 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uL3 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0087, Bacteria |
HOGENOMi | CLU_044142_4_1_0 |
OMAi | KGMRMAG |
OrthoDBi | 1270636at2 |
Family and domain databases
HAMAPi | MF_01325_B, Ribosomal_L3_B, 1 hit |
InterProi | View protein in InterPro IPR000597, Ribosomal_L3 IPR019927, Ribosomal_L3_bac/org-type IPR019926, Ribosomal_L3_CS IPR009000, Transl_B-barrel_sf |
PANTHERi | PTHR11229, PTHR11229, 1 hit |
Pfami | View protein in Pfam PF00297, Ribosomal_L3, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit |
TIGRFAMsi | TIGR03625, L3_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00474, RIBOSOMAL_L3, 1 hit |
i Sequence
Sequence statusi: Complete.
Q72I04-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKGILGVKVG MTRIFRDDRA VPVTVILAGP CPVVQRRTPE KDGYTAVQLG
60 70 80 90 100
FLPQNPKRVN RPLKGHFAKA GVEPVRILRE IRDFNPEGDT VTVEIFKPGE
110 120 130 140 150
RVDVTGTSKG RGFAGVMKRW NFAGGPDSHG AHKIHRHPGS IGNRKTPGRV
160 170 180 190 200
YKGKKMAGHY GAERVTVMNL EVVDVIPEEN LLLVKGAVPG PNGGLVIVRE
TKKAAK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017221 Genomic DNA Translation: AAS81670.1 |
RefSeqi | WP_011173714.1, NC_005835.1 |
Genome annotation databases
EnsemblBacteriai | AAS81670; AAS81670; TT_C1328 |
GeneIDi | 3167929 |
KEGGi | tth:TT_C1328 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017221 Genomic DNA Translation: AAS81670.1 |
RefSeqi | WP_011173714.1, NC_005835.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4V4I | X-ray | 3.71 | C | 1-206 | [»] | |
4V4J | X-ray | 3.83 | C | 1-206 | [»] | |
4V63 | X-ray | 3.21 | BE/DE | 1-206 | [»] | |
4V67 | X-ray | 3.00 | BE/DE | 1-206 | [»] | |
4V7P | X-ray | 3.62 | BD/CD | 1-206 | [»] | |
4V83 | X-ray | 3.50 | BD/DD | 1-204 | [»] | |
4V84 | X-ray | 3.40 | BD/DD | 1-204 | [»] | |
4V9J | X-ray | 3.86 | BE/DE | 1-205 | [»] | |
4V9K | X-ray | 3.50 | BE/DE | 1-205 | [»] | |
4V9L | X-ray | 3.50 | BE/DE | 1-205 | [»] | |
4V9M | X-ray | 4.00 | BE/DE | 1-205 | [»] | |
4V9N | X-ray | 3.40 | BE/DE | 1-204 | [»] | |
4V9Q | X-ray | 3.40 | AE/CE | 1-204 | [»] | |
4W29 | X-ray | 3.80 | BE/DE | 1-205 | [»] | |
4XEJ | X-ray | 3.80 | AL03/BL03 | 1-204 | [»] | |
5J4D | X-ray | 3.10 | F/KB | 1-206 | [»] | |
SMRi | Q72I04 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 262724.TT_C1328 |
Genome annotation databases
EnsemblBacteriai | AAS81670; AAS81670; TT_C1328 |
GeneIDi | 3167929 |
KEGGi | tth:TT_C1328 |
Phylogenomic databases
eggNOGi | COG0087, Bacteria |
HOGENOMi | CLU_044142_4_1_0 |
OMAi | KGMRMAG |
OrthoDBi | 1270636at2 |
Miscellaneous databases
EvolutionaryTracei | Q72I04 |
Family and domain databases
HAMAPi | MF_01325_B, Ribosomal_L3_B, 1 hit |
InterProi | View protein in InterPro IPR000597, Ribosomal_L3 IPR019927, Ribosomal_L3_bac/org-type IPR019926, Ribosomal_L3_CS IPR009000, Transl_B-barrel_sf |
PANTHERi | PTHR11229, PTHR11229, 1 hit |
Pfami | View protein in Pfam PF00297, Ribosomal_L3, 1 hit |
SUPFAMi | SSF50447, SSF50447, 1 hit |
TIGRFAMsi | TIGR03625, L3_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00474, RIBOSOMAL_L3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RL3_THET2 | |
Accessioni | Q72I04Primary (citable) accession number: Q72I04 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- Ribosomal proteins
Ribosomal proteins families and list of entries - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families