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Entry version 128 (07 Apr 2021)
Sequence version 1 (05 Jul 2004)
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Protein

Cytochrome c nitrite reductase subunit NrfA

Gene

nrfA

Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalytic subunit of the cytochrome c nitrite reductase holocomplex NrfHA (PubMed:11004582, PubMed:25534748, PubMed:17139260, PubMed:18597779). Has both nitrite and sulfite reductase activities (PubMed:11004582). Catalyzes the reduction of nitrite to ammonia, consuming six electrons acquired by the electron donor subunit NrfH from the menaquinone pool, in an anaerobic respiratory process of nitrite (PubMed:11004582, PubMed:25534748, PubMed:17139260, PubMed:18597779). The other biological function of the NrfHA holocomplex is to detoxify nitrite (PubMed:15547266, PubMed:25534748). This function is essential for the survival of this organism as it enables it to overcome inhibition by nitrite, which is produced by other organisms living in the same environment (Probable).Curated5 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Protein has several cofactor binding sites:

Redox potential

E0 is -50 mV for the lysine-coordinated heme 1.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

    1. Vmax=685 µmol/min/mg enzyme for the nitrite reductase activity1 Publication
    2. Vmax=1.0 µmol/min/mg enzyme for the sulfite reductase activity1 Publication

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi78Calcium 1; via carbonyl oxygenCombined sources2 Publications1
    Metal bindingi117Calcium 1Combined sources2 Publications1
    Metal bindingi118Calcium 1; via carbonyl oxygenCombined sources2 Publications1
    Metal bindingi121Iron (heme 3 axial ligand); via tele nitrogenCombined sources2 Publications1
    <p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei147Heme 1; covalentCombined sources1 Publication1
    Binding sitei150Heme 1; covalentCombined sources2 Publications1
    Metal bindingi151Iron (heme 1 axial ligand)Combined sources2 Publications1
    Binding sitei187Heme 2; covalentCombined sources1 Publication1
    Binding sitei190Heme 2; covalentCombined sources1 Publication1
    Metal bindingi191Iron (heme 2 axial ligand); via tele nitrogenCombined sources2 Publications1
    Binding sitei229Heme 3; covalentCombined sources2 Publications1
    Binding sitei232Heme 3; covalentCombined sources1 Publication1
    Metal bindingi233Iron (heme 3 axial ligand); via tele nitrogenCombined sources2 Publications1
    Metal bindingi235Calcium 2Combined sources2 Publications1
    Metal bindingi236Calcium 2; via carbonyl oxygenCombined sources2 Publications1
    Metal bindingi295Calcium 2; via carbonyl oxygenCombined sources2 Publications1
    Metal bindingi297Calcium 2Combined sources2 Publications1
    Metal bindingi309Iron (heme 5 axial ligand); via tele nitrogenCombined sources2 Publications1
    Binding sitei316Heme 4; covalentCombined sources2 Publications1
    Binding sitei319Heme 4; covalentCombined sources1 Publication1
    Metal bindingi320Iron (heme 4 axial ligand); via tele nitrogenCombined sources2 Publications1
    Metal bindingi335Iron (heme 2 axial ligand); via tele nitrogenCombined sources2 Publications1
    Binding sitei349Heme 5; covalentCombined sources2 Publications1
    Binding sitei352Heme 5; covalentCombined sources2 Publications1
    Metal bindingi353Iron (heme 5 axial ligand); via tele nitrogenCombined sources2 Publications1
    Metal bindingi434Iron (heme 4 axial ligand); via tele nitrogenCombined sources2 Publications1

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    Biological processStress response
    LigandCalcium, Heme, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyc Collection of Pathway/Genome Databases

    More...
    BioCyci
    DVUL882:G1GT1-649-MONOMER

    BRENDA Comprehensive Enzyme Information System

    More...
    BRENDAi
    1.7.7.1, 1914

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Cytochrome c nitrite reductase subunit NrfA2 Publications (EC:1.7.2.2Sequence analysis4 Publications)
    Short name:
    cNiR subunit NrfA1 Publication
    Alternative name(s):
    Cytochrome c-type protein NrfACurated
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:nrfA1 PublicationImported
    Ordered Locus Names:DVU_0625Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDesulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)Imported
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri882 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000002194 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    <p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

    Sensitive to nitrite, but not to nitrate (PubMed:15547266). Loss of anaerobical respiration of nitrite, but the mutant is still able to utilize nitrite as a nitrogen source for growth (PubMed:25534748).2 Publications

    Chemistry databases

    Drug and drug target database

    More...
    DrugBanki
    DB07918, 2-heptyl-4-hydroxyquinoline N-oxide

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 241 PublicationAdd BLAST24
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500428521425 – 524Cytochrome c nitrite reductase subunit NrfA1 PublicationAdd BLAST500

    Proteomic databases

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q72EF3

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    <p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

    Expression is induced in response to nitrite stress. Not induced by nitrate.1 Publication

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Component of the NrfHA cytochrome c nitrite reductase complex composed of 4 NrfA catalytic subunits and 2 NrfH quinone-binding subunits (PubMed:17139260, PubMed:18597779, PubMed:22519292). NrfA homodimer interacts with NrfH (PubMed:16754983, PubMed:17139260).

    4 Publications

    Sites

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei59Interaction with NrfHCombined sources1 Publication1

    Protein-protein interaction databases

    STRING: functional protein association networks

    More...
    STRINGi
    882.DVU_0625

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    1524
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q72EF3

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    Protein Data Bank in Europe - Knowledge Base

    More...
    PDBe-KBi
    Search...

    Miscellaneous databases

    Relative evolutionary importance of amino acids within a protein sequence

    More...
    EvolutionaryTracei
    Q72EF3

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni29 – 39Interaction with NrfHCombined sources1 PublicationAdd BLAST11
    Regioni221 – 222Interaction with NrfHCombined sources1 Publication2
    Regioni318 – 331Interaction with NrfHCombined sources1 PublicationAdd BLAST14
    Regioni351 – 355Interaction with NrfHCombined sources1 Publication5

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Belongs to the cytochrome c-552 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    COG3303, Bacteria

    The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

    More...
    HOGENOMi
    CLU_035040_1_0_7

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    EMVILWA

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q72EF3

    Family and domain databases

    Conserved Domains Database

    More...
    CDDi
    cd00548, NrfA-like, 1 hit

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR003321, Cyt_c552
    IPR011031, Multihaem_cyt
    IPR036280, Multihaem_cyt_sf

    The PANTHER Classification System

    More...
    PANTHERi
    PTHR30633, PTHR30633, 1 hit

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF02335, Cytochrom_C552, 1 hit

    PIRSF; a whole-protein classification database

    More...
    PIRSFi
    PIRSF000243, Cyt_c552, 1 hit

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF48695, SSF48695, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS51008, MULTIHEME_CYTC, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

    Q72EF3-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MNNQKTFKGL RLAALGLVAV AAFTAGCSDV STELKTPVYK TKLTAEEIRN
    60 70 80 90 100
    SAFKPEFPKQ YASYERNDET TVMTEYKGSV PFNKNDNVNP LPEGYRHAQP
    110 120 130 140 150
    YLKNLWLGYP FMYEYREARG HTYAIQDFLH IDRINRYAEK GGLPATCWNC
    160 170 180 190 200
    KTPKMMEWVK ESGDGFWAKD VNEFRDKIDM KDHTIGCATC HDPQTMELRI
    210 220 230 240 250
    TSVPLTDYLV SQGKDPKKLP RNEMRALVCG QCHVEYYFNG PTMGVNKKPV
    260 270 280 290 300
    FPWAEGFDPA DMYRYYDKHG DLQVKGFEGK FADWTHPASK TPMIKAQHPE
    310 320 330 340 350
    YETWINGTHG AAGVTCADCH MSYTRSDDKK KISSHWWTSP MKDPEMRACR
    360 370 380 390 400
    QCHSDKTPDY LKSRVLFTQK RTFDLLLAAQ EVSVKAHEAV RLANEYQGAK
    410 420 430 440 450
    AAGYDDLMIQ AREMVRKGQF FWDYVSAENS VGFHNPAKAL DTLAQSQQFS
    460 470 480 490 500
    QKAIDLAMEA TQYGIGKDLS GDIKTIVPPI LKMNRKLQQD PEFMKTHKWF
    510 520
    QYLPVLPKAD QVWDGQKRLV SAKQ
    Length:524
    Mass (Da):60,003
    Last modified:July 5, 2004 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7E8B228E5BEDF12F
    GO

    Experimental Info

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti159 – 160VK → FP in CAG27083 (PubMed:19712292).Curated2

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AE017285 Genomic DNA Translation: AAS95106.1
    AJ697975 Genomic DNA Translation: CAG27083.1

    NCBI Reference Sequences

    More...
    RefSeqi
    WP_010937928.1, NZ_CABHLV010000001.1
    YP_009847.1, NC_002937.3

    Genome annotation databases

    Ensembl bacterial and archaeal genome annotation project

    More...
    EnsemblBacteriai
    AAS95106; AAS95106; DVU_0625

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    dvu:DVU0625

    Pathosystems Resource Integration Center (PATRIC)

    More...
    PATRICi
    fig|882.5.peg.583

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AE017285 Genomic DNA Translation: AAS95106.1
    AJ697975 Genomic DNA Translation: CAG27083.1
    RefSeqiWP_010937928.1, NZ_CABHLV010000001.1
    YP_009847.1, NC_002937.3

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    2J7AX-ray2.30A/B/D/E/G/H/J/K/M/N/P/Q25-524[»]
    2VR0X-ray2.80A/B/D/E1-524[»]
    SMRiQ72EF3
    ModBaseiSearch...
    PDBe-KBiSearch...

    Protein-protein interaction databases

    STRINGi882.DVU_0625

    Chemistry databases

    DrugBankiDB07918, 2-heptyl-4-hydroxyquinoline N-oxide

    Proteomic databases

    PaxDbiQ72EF3

    Genome annotation databases

    EnsemblBacteriaiAAS95106; AAS95106; DVU_0625
    KEGGidvu:DVU0625
    PATRICifig|882.5.peg.583

    Phylogenomic databases

    eggNOGiCOG3303, Bacteria
    HOGENOMiCLU_035040_1_0_7
    OMAiEMVILWA
    PhylomeDBiQ72EF3

    Enzyme and pathway databases

    BioCyciDVUL882:G1GT1-649-MONOMER
    BRENDAi1.7.7.1, 1914

    Miscellaneous databases

    EvolutionaryTraceiQ72EF3

    Family and domain databases

    CDDicd00548, NrfA-like, 1 hit
    InterProiView protein in InterPro
    IPR003321, Cyt_c552
    IPR011031, Multihaem_cyt
    IPR036280, Multihaem_cyt_sf
    PANTHERiPTHR30633, PTHR30633, 1 hit
    PfamiView protein in Pfam
    PF02335, Cytochrom_C552, 1 hit
    PIRSFiPIRSF000243, Cyt_c552, 1 hit
    SUPFAMiSSF48695, SSF48695, 1 hit
    PROSITEiView protein in PROSITE
    PS51008, MULTIHEME_CYTC, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNRFA_DESVH
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q72EF3
    Secondary accession number(s): Q6ZXS8
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 25, 2018
    Last sequence update: July 5, 2004
    Last modified: April 7, 2021
    This is version 128 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families
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