UniProtKB - Q72CI5 (RS12_DESVH)
Protein
30S ribosomal protein S12
Gene
rpsL
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Status
Functioni
With S4 and S5 plays an important role in translational accuracy.UniRule annotation
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.UniRule annotation
GO - Molecular functioni
- rRNA binding Source: UniProtKB-UniRule
- structural constituent of ribosome Source: InterPro
- tRNA binding Source: UniProtKB-UniRule
GO - Biological processi
- translation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding |
Enzyme and pathway databases
BioCyci | DVUL882:G1GT1-1331-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: 30S ribosomal protein S12UniRule annotation |
Gene namesi | Name:rpsLUniRule annotation Ordered Locus Names:DVU_1298 |
Organismi | Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303) |
Taxonomic identifieri | 882 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000146218 | 1 – 123 | 30S ribosomal protein S12Add BLAST | 123 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 89 | 3-methylthioaspartic acidBy similarity | 1 |
Keywords - PTMi
MethylationProteomic databases
PaxDbi | Q72CI5 |
Interactioni
Subunit structurei
Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
UniRule annotationProtein-protein interaction databases
STRINGi | 882.DVU_1298 |
Family & Domainsi
Sequence similaritiesi
Belongs to the universal ribosomal protein uS12 family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0048, Bacteria |
HOGENOMi | CLU_104295_1_2_7 |
OMAi | SPALEKC |
PhylomeDBi | Q72CI5 |
Family and domain databases
CDDi | cd03368, Ribosomal_S12, 1 hit |
HAMAPi | MF_00403_B, Ribosomal_S12_B, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR006032, Ribosomal_S12/S23 IPR005679, Ribosomal_S12_bac |
PANTHERi | PTHR11652, PTHR11652, 1 hit |
Pfami | View protein in Pfam PF00164, Ribosom_S12_S23, 1 hit |
PIRSFi | PIRSF002133, Ribosomal_S12/S23, 1 hit |
PRINTSi | PR01034, RIBOSOMALS12 |
SUPFAMi | SSF50249, SSF50249, 1 hit |
TIGRFAMsi | TIGR00981, rpsL_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00055, RIBOSOMAL_S12, 1 hit |
i Sequence
Sequence statusi: Complete.
Q72CI5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPTINQLIRK ERKKVVKRKK TPALQACPQR RGVCTRVYTT TPKKPNSALR
60 70 80 90 100
KVARVRLTNG LEVTAYIPGE GHNLQEHSVV MIRGGRVKDL PGVRYHIVRG
110 120
TLDTSGVQDR RQGRSKYGAK RPK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017285 Genomic DNA Translation: AAS95776.1 |
RefSeqi | WP_010938593.1, NZ_CABHLV010000001.1 YP_010517.1, NC_002937.3 |
Genome annotation databases
EnsemblBacteriai | AAS95776; AAS95776; DVU_1298 |
KEGGi | dvu:DVU1298 |
PATRICi | fig|882.5.peg.1210 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017285 Genomic DNA Translation: AAS95776.1 |
RefSeqi | WP_010938593.1, NZ_CABHLV010000001.1 YP_010517.1, NC_002937.3 |
3D structure databases
SMRi | Q72CI5 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 882.DVU_1298 |
Proteomic databases
PaxDbi | Q72CI5 |
Genome annotation databases
EnsemblBacteriai | AAS95776; AAS95776; DVU_1298 |
KEGGi | dvu:DVU1298 |
PATRICi | fig|882.5.peg.1210 |
Phylogenomic databases
eggNOGi | COG0048, Bacteria |
HOGENOMi | CLU_104295_1_2_7 |
OMAi | SPALEKC |
PhylomeDBi | Q72CI5 |
Enzyme and pathway databases
BioCyci | DVUL882:G1GT1-1331-MONOMER |
Family and domain databases
CDDi | cd03368, Ribosomal_S12, 1 hit |
HAMAPi | MF_00403_B, Ribosomal_S12_B, 1 hit |
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR006032, Ribosomal_S12/S23 IPR005679, Ribosomal_S12_bac |
PANTHERi | PTHR11652, PTHR11652, 1 hit |
Pfami | View protein in Pfam PF00164, Ribosom_S12_S23, 1 hit |
PIRSFi | PIRSF002133, Ribosomal_S12/S23, 1 hit |
PRINTSi | PR01034, RIBOSOMALS12 |
SUPFAMi | SSF50249, SSF50249, 1 hit |
TIGRFAMsi | TIGR00981, rpsL_bact, 1 hit |
PROSITEi | View protein in PROSITE PS00055, RIBOSOMAL_S12, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RS12_DESVH | |
Accessioni | Q72CI5Primary (citable) accession number: Q72CI5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 27, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Ribosomal proteins
Ribosomal proteins families and list of entries