UniProtKB - Q72AY0 (Q72AY0_DESVH)
Protein
Apolipoprotein N-acyltransferase
Gene
cutE
Organism
Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)
Status
Functioni
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.UniRule annotation
Catalytic activityi
- a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 1-lyso-glycerophospholipid + H+ + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]UniRule annotationEC:2.3.1.269UniRule annotation
: lipoprotein biosynthesis (N-acyl transfer) Pathwayi
This protein is involved in the pathway lipoprotein biosynthesis (N-acyl transfer), which is part of Protein modification.UniRule annotationView all proteins of this organism that are known to be involved in the pathway lipoprotein biosynthesis (N-acyl transfer) and in Protein modification.
GO - Molecular functioni
- N-acyltransferase activity Source: UniProtKB-UniRule
GO - Biological processi
- lipoprotein biosynthetic process Source: UniProtKB-UniRule
Keywordsi
Molecular function | AcyltransferaseUniRule annotationImportedARBA annotation, Transferase |
Enzyme and pathway databases
BioCyci | DVUL882:G1GT1-1909-MONOMER |
UniPathwayi | UPA00666 |
Names & Taxonomyi
Protein namesi | Recommended name: Apolipoprotein N-acyltransferaseUniRule annotation (EC:2.3.1.269UniRule annotation)Short name: ALP N-acyltransferaseUniRule annotation |
Gene namesi | Name:cutEImported Synonyms:lntUniRule annotation Ordered Locus Names:DVU_1860Imported |
Organismi | Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)Imported |
Taxonomic identifieri | 882 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 29 – 45 | HelicalUniRule annotationAdd BLAST | 17 | |
Transmembranei | 52 – 70 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 82 – 107 | HelicalUniRule annotationAdd BLAST | 26 | |
Transmembranei | 119 – 142 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 154 – 176 | HelicalUniRule annotationAdd BLAST | 23 | |
Transmembranei | 188 – 206 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 474 – 495 | HelicalUniRule annotationAdd BLAST | 22 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-KW
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membraneUniRule annotation, Cell membrane, MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 223 – 468 | CN hydrolaseInterPro annotationAdd BLAST | 246 |
Sequence similaritiesi
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationPhylogenomic databases
eggNOGi | COG0815, Bacteria |
HOGENOMi | CLU_019563_1_2_7 |
OMAi | PIGEFVP |
PhylomeDBi | Q72AY0 |
Family and domain databases
CDDi | cd07571, ALP_N-acyl_transferase, 1 hit |
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01148, Lnt, 1 hit |
InterProi | View protein in InterPro IPR004563, Apolipo_AcylTrfase IPR003010, C-N_Hydrolase IPR036526, C-N_Hydrolase_sf |
Pfami | View protein in Pfam PF00795, CN_hydrolase, 1 hit |
SUPFAMi | SSF56317, SSF56317, 1 hit |
TIGRFAMsi | TIGR00546, lnt, 1 hit |
PROSITEi | View protein in PROSITE PS50263, CN_HYDROLASE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q72AY0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MHQFLTPLVA ILGLWLGFPN PLGQVPLLAL LYPAALYACA LRASTWQTAL
60 70 80 90 100
RSGWLTGMTA ASACLYWLAV PVHDFGDLPW VLAVPCAVVI GAYVGLYAGL
110 120 130 140 150
FCMATHLFRD RTSPLRRALL AGVLWFLLEW LRGVLFTGFP WLSLSSAFVP
160 170 180 190 200
WPVAVQFASV VGGYGLSGIM AAIACLAYES LHGRQTSLCA ATLSGFTLVI
210 220 230 240 250
CAWGIMTLST PLPQSSPFGA LMIQGNINQD QKWEAAFQKG TVDKYLALTR
260 270 280 290 300
QALGGERPRL VIWPETSMPF YFQEHKTYGP VVRDFVKENN IALLIGTPGY
310 320 330 340 350
DRKTGAGYAL FNRAYLLGAD GETLGHYDKE HLVPFGEYLP PGLNLPFLAK
360 370 380 390 400
LLQGVGDFTP GTRTQPLKLG DLALGMLICY ESIFPELALQ RVADGANVLV
410 420 430 440 450
NISNDAWFGF TAAPEQHIQL SAMRAVEQGR FLLRGTNTGI TAAIDPHGRI
460 470 480 490 500
IGRSNVFVDA AVFVTASPLS SRTVYFHIAA WLPLAGVALA LLLLLRPVRP
SA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017285 Genomic DNA Translation: AAS96336.1 |
RefSeqi | WP_010939146.1, NZ_CABHLV010000001.1 YP_011077.1, NC_002937.3 |
Genome annotation databases
EnsemblBacteriai | AAS96336; AAS96336; DVU_1860 |
KEGGi | dvu:DVU1860 |
PATRICi | fig|882.5.peg.1704 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE017285 Genomic DNA Translation: AAS96336.1 |
RefSeqi | WP_010939146.1, NZ_CABHLV010000001.1 YP_011077.1, NC_002937.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 882.DVU_1860 |
Proteomic databases
PaxDbi | Q72AY0 |
Genome annotation databases
EnsemblBacteriai | AAS96336; AAS96336; DVU_1860 |
KEGGi | dvu:DVU1860 |
PATRICi | fig|882.5.peg.1704 |
Phylogenomic databases
eggNOGi | COG0815, Bacteria |
HOGENOMi | CLU_019563_1_2_7 |
OMAi | PIGEFVP |
PhylomeDBi | Q72AY0 |
Enzyme and pathway databases
UniPathwayi | UPA00666 |
BioCyci | DVUL882:G1GT1-1909-MONOMER |
Family and domain databases
CDDi | cd07571, ALP_N-acyl_transferase, 1 hit |
Gene3Di | 3.60.110.10, 1 hit |
HAMAPi | MF_01148, Lnt, 1 hit |
InterProi | View protein in InterPro IPR004563, Apolipo_AcylTrfase IPR003010, C-N_Hydrolase IPR036526, C-N_Hydrolase_sf |
Pfami | View protein in Pfam PF00795, CN_hydrolase, 1 hit |
SUPFAMi | SSF56317, SSF56317, 1 hit |
TIGRFAMsi | TIGR00546, lnt, 1 hit |
PROSITEi | View protein in PROSITE PS50263, CN_HYDROLASE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q72AY0_DESVH | |
Accessioni | Q72AY0Primary (citable) accession number: Q72AY0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |