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Entry version 125 (11 Dec 2019)
Sequence version 2 (11 Jul 2006)
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Protein

Transmembrane and ubiquitin-like domain-containing protein 2

Gene

TMUB2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane and ubiquitin-like domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMUB2
ORF Names:FP2653, UNQ1897/PRO4343
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000168591.15

Human Gene Nomenclature Database

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HGNCi
HGNC:28459 TMUB2

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q71RG4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei36 – 56HelicalSequence analysisAdd BLAST21
Transmembranei266 – 286HelicalSequence analysisAdd BLAST21
Transmembranei295 – 315HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000168591

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA145147917

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q71RG4 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMUB2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
110287995

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002453121 – 321Transmembrane and ubiquitin-like domain-containing protein 2Add BLAST321

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q71RG4

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q71RG4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q71RG4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q71RG4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q71RG4

PeptideAtlas

More...
PeptideAtlasi
Q71RG4

PRoteomics IDEntifications database

More...
PRIDEi
Q71RG4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
68616 [Q71RG4-1]
68617 [Q71RG4-2]
68618 [Q71RG4-3]
68619 [Q71RG4-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q71RG4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q71RG4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000168591 Expressed in 223 organ(s), highest expression level in vagina

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q71RG4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q71RG4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043137

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122537, 13 interactors

Database of interacting proteins

More...
DIPi
DIP-60896N

Protein interaction database and analysis system

More...
IntActi
Q71RG4, 30 interactors

Molecular INTeraction database

More...
MINTi
Q71RG4

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000466971

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q71RG4 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q71RG4

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini174 – 247Ubiquitin-likePROSITE-ProRule annotationAdd BLAST74

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IG1T Eukaryota
ENOG4111WH7 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014069

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232067

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q71RG4

KEGG Orthology (KO)

More...
KOi
K23340

Identification of Orthologs from Complete Genome Data

More...
OMAi
MKFIYQG

Database of Orthologous Groups

More...
OrthoDBi
1164744at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q71RG4

TreeFam database of animal gene trees

More...
TreeFami
TF329265

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR040352 TMUB1/2
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf

The PANTHER Classification System

More...
PANTHERi
PTHR14557 PTHR14557, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00240 ubiquitin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00213 UBQ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q71RG4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MISRHLQNNL MSVDPASSQA MELSDVTLIE GVGNEVMVVA GVVVLILALV
60 70 80 90 100
LAWLSTYVAD SGSNQLLGAI VSAGDTSVLH LGHVDHLVAG QGNPEPTELP
110 120 130 140 150
HPSEGNDEKA EEAGEGRGDS TGEAGAGGGV EPSLEHLLDI QGLPKRQAGA
160 170 180 190 200
GSSSPEAPLR SEDSTCLPPS PGLITVRLKF LNDTEELAVA RPEDTVGALK
210 220 230 240 250
SKYFPGQESQ MKLIYQGRLL QDPARTLRSL NITDNCVIHC HRSPPGSAVP
260 270 280 290 300
GPSASLAPSA TEPPSLGVNV GSLMVPVFVV LLGVVWYFRI NYRQFFTAPA
310 320
TVSLVGVTVF FSFLVFGMYG R
Length:321
Mass (Da):33,788
Last modified:July 11, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC48656AD40A72454
GO
Isoform 2 (identifier: Q71RG4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: Missing.

Show »
Length:301
Mass (Da):31,607
Checksum:i25469114D9C227BF
GO
Isoform 3 (identifier: Q71RG4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: Missing.
     201-201: S → R
     202-321: Missing.

Show »
Length:181
Mass (Da):18,542
Checksum:i5F40EF668D941650
GO
Isoform 4 (identifier: Q71RG4-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-20: Missing.
     105-114: GNDEKAEEAG → ANTSLDKKAR
     115-321: Missing.

Show »
Length:94
Mass (Da):9,709
Checksum:iC9FF0962A4DF1FE9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7ESS3E7ESS3_HUMAN
Transmembrane and ubiquitin-like do...
TMUB2
264Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EKW3K7EKW3_HUMAN
Transmembrane and ubiquitin-like do...
TMUB2
194Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPS1K7EPS1_HUMAN
Transmembrane and ubiquitin-like do...
TMUB2
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJF7K7EJF7_HUMAN
Transmembrane and ubiquitin-like do...
TMUB2
61Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ESL5K7ESL5_HUMAN
Transmembrane and ubiquitin-like do...
TMUB2
75Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti265S → R in CAD38755 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_052695228R → H. Corresponds to variant dbSNP:rs9895154Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0197001 – 20Missing in isoform 2, isoform 3 and isoform 4. 5 PublicationsAdd BLAST20
Alternative sequenceiVSP_019701105 – 114GNDEKAEEAG → ANTSLDKKAR in isoform 4. 1 Publication10
Alternative sequenceiVSP_019702115 – 321Missing in isoform 4. 1 PublicationAdd BLAST207
Alternative sequenceiVSP_019703201S → R in isoform 3. 1 Publication1
Alternative sequenceiVSP_019704202 – 321Missing in isoform 3. 1 PublicationAdd BLAST120

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF370373 mRNA Translation: AAQ15209.1
AY358780 mRNA Translation: AAQ89140.1
AK021759 mRNA Translation: BAB13886.1
AK096631 mRNA Translation: BAG53343.1
CR622157 mRNA No translation available.
AL833899 mRNA Translation: CAD38755.1
BC001792 mRNA Translation: AAH01792.1
BC004306 mRNA Translation: AAH04306.1
BC063489 mRNA Translation: AAH63489.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11479.1 [Q71RG4-2]
CCDS54134.1 [Q71RG4-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001070142.1, NM_001076674.1 [Q71RG4-1]
NP_001317164.1, NM_001330235.1
NP_077012.2, NM_024107.2 [Q71RG4-2]
NP_803190.2, NM_177441.2 [Q71RG4-2]
XP_011523500.1, XM_011525198.2
XP_011523503.1, XM_011525201.2 [Q71RG4-1]
XP_011523507.1, XM_011525205.2 [Q71RG4-2]
XP_011523508.1, XM_011525206.2
XP_011523509.1, XM_011525207.2
XP_011523510.1, XM_011525208.2
XP_011523511.1, XM_011525209.2
XP_016880537.1, XM_017025048.1
XP_016880538.1, XM_017025049.1
XP_016880539.1, XM_017025050.1
XP_016880540.1, XM_017025051.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000319511; ENSP00000313214; ENSG00000168591 [Q71RG4-2]
ENST00000357984; ENSP00000350672; ENSG00000168591 [Q71RG4-2]
ENST00000538716; ENSP00000444565; ENSG00000168591 [Q71RG4-1]
ENST00000587172; ENSP00000465153; ENSG00000168591 [Q71RG4-4]
ENST00000587989; ENSP00000466971; ENSG00000168591 [Q71RG4-1]
ENST00000589785; ENSP00000467364; ENSG00000168591 [Q71RG4-2]
ENST00000589856; ENSP00000467960; ENSG00000168591 [Q71RG4-3]
ENST00000590235; ENSP00000465015; ENSG00000168591 [Q71RG4-4]
ENST00000592825; ENSP00000466189; ENSG00000168591 [Q71RG4-4]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79089

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79089

UCSC genome browser

More...
UCSCi
uc002ifo.4 human [Q71RG4-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF370373 mRNA Translation: AAQ15209.1
AY358780 mRNA Translation: AAQ89140.1
AK021759 mRNA Translation: BAB13886.1
AK096631 mRNA Translation: BAG53343.1
CR622157 mRNA No translation available.
AL833899 mRNA Translation: CAD38755.1
BC001792 mRNA Translation: AAH01792.1
BC004306 mRNA Translation: AAH04306.1
BC063489 mRNA Translation: AAH63489.1
CCDSiCCDS11479.1 [Q71RG4-2]
CCDS54134.1 [Q71RG4-1]
RefSeqiNP_001070142.1, NM_001076674.1 [Q71RG4-1]
NP_001317164.1, NM_001330235.1
NP_077012.2, NM_024107.2 [Q71RG4-2]
NP_803190.2, NM_177441.2 [Q71RG4-2]
XP_011523500.1, XM_011525198.2
XP_011523503.1, XM_011525201.2 [Q71RG4-1]
XP_011523507.1, XM_011525205.2 [Q71RG4-2]
XP_011523508.1, XM_011525206.2
XP_011523509.1, XM_011525207.2
XP_011523510.1, XM_011525208.2
XP_011523511.1, XM_011525209.2
XP_016880537.1, XM_017025048.1
XP_016880538.1, XM_017025049.1
XP_016880539.1, XM_017025050.1
XP_016880540.1, XM_017025051.1

3D structure databases

SMRiQ71RG4
ModBaseiSearch...

Protein-protein interaction databases

BioGridi122537, 13 interactors
DIPiDIP-60896N
IntActiQ71RG4, 30 interactors
MINTiQ71RG4
STRINGi9606.ENSP00000466971

PTM databases

iPTMnetiQ71RG4
PhosphoSitePlusiQ71RG4

Polymorphism and mutation databases

BioMutaiTMUB2
DMDMi110287995

Proteomic databases

EPDiQ71RG4
jPOSTiQ71RG4
MassIVEiQ71RG4
MaxQBiQ71RG4
PaxDbiQ71RG4
PeptideAtlasiQ71RG4
PRIDEiQ71RG4
ProteomicsDBi68616 [Q71RG4-1]
68617 [Q71RG4-2]
68618 [Q71RG4-3]
68619 [Q71RG4-4]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
79089

Genome annotation databases

EnsembliENST00000319511; ENSP00000313214; ENSG00000168591 [Q71RG4-2]
ENST00000357984; ENSP00000350672; ENSG00000168591 [Q71RG4-2]
ENST00000538716; ENSP00000444565; ENSG00000168591 [Q71RG4-1]
ENST00000587172; ENSP00000465153; ENSG00000168591 [Q71RG4-4]
ENST00000587989; ENSP00000466971; ENSG00000168591 [Q71RG4-1]
ENST00000589785; ENSP00000467364; ENSG00000168591 [Q71RG4-2]
ENST00000589856; ENSP00000467960; ENSG00000168591 [Q71RG4-3]
ENST00000590235; ENSP00000465015; ENSG00000168591 [Q71RG4-4]
ENST00000592825; ENSP00000466189; ENSG00000168591 [Q71RG4-4]
GeneIDi79089
KEGGihsa:79089
UCSCiuc002ifo.4 human [Q71RG4-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79089
EuPathDBiHostDB:ENSG00000168591.15

GeneCards: human genes, protein and diseases

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GeneCardsi
TMUB2
HGNCiHGNC:28459 TMUB2
HPAiHPA043137
neXtProtiNX_Q71RG4
OpenTargetsiENSG00000168591
PharmGKBiPA145147917

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IG1T Eukaryota
ENOG4111WH7 LUCA
GeneTreeiENSGT00390000014069
HOGENOMiHOG000232067
InParanoidiQ71RG4
KOiK23340
OMAiMKFIYQG
OrthoDBi1164744at2759
PhylomeDBiQ71RG4
TreeFamiTF329265

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TMUB2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
TMUB2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79089
PharosiQ71RG4 Tdark

Protein Ontology

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PROi
PR:Q71RG4
RNActiQ71RG4 protein

Gene expression databases

BgeeiENSG00000168591 Expressed in 223 organ(s), highest expression level in vagina
ExpressionAtlasiQ71RG4 baseline and differential
GenevisibleiQ71RG4 HS

Family and domain databases

InterProiView protein in InterPro
IPR040352 TMUB1/2
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf
PANTHERiPTHR14557 PTHR14557, 1 hit
PfamiView protein in Pfam
PF00240 ubiquitin, 1 hit
SMARTiView protein in SMART
SM00213 UBQ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50053 UBIQUITIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMUB2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q71RG4
Secondary accession number(s): B3KU81
, Q8NDI2, Q9BPZ5, Q9HAG3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2006
Last sequence update: July 11, 2006
Last modified: December 11, 2019
This is version 125 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
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