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Entry version 71 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Xin actin-binding repeat-containing protein 2

Gene

Xirp2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protects actin filaments from depolymerization.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Xin actin-binding repeat-containing protein 2
Alternative name(s):
Beta-xin
Cardiomyopathy-associated protein 3
L-NAME-induced actin cytoskeletal protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Xirp2
Synonyms:Cmya3, Xin2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Rat genome database

More...
RGDi
1302980, Xirp2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell junction

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003169891 – 3302Xin actin-binding repeat-containing protein 2Add BLAST3302

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei565PhosphoserineCombined sources1
Modified residuei633PhosphoserineCombined sources1
Modified residuei813PhosphoserineBy similarity1
Modified residuei1210PhosphoserineCombined sources1
Modified residuei1573PhosphoserineCombined sources1
Modified residuei1930PhosphothreonineCombined sources1
Modified residuei1935PhosphoserineCombined sources1
Modified residuei2158PhosphoserineBy similarity1
Modified residuei2198PhosphoserineCombined sources1
Modified residuei2211PhosphoserineCombined sources1
Modified residuei2252PhosphoserineCombined sources1
Modified residuei2987PhosphoserineBy similarity1
Modified residuei3225PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q71LX6

PRoteomics IDEntifications database

More...
PRIDEi
Q71LX6

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q71LX6

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q71LX6

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ACTN2.

Interacts with F-actin (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
259825, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000048045

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati306 – 321Xin 1Add BLAST16
Repeati341 – 356Xin 2Add BLAST16
Repeati381 – 396Xin 3Add BLAST16
Repeati418 – 433Xin 4Add BLAST16
Repeati456 – 471Xin 5Add BLAST16
Repeati496 – 511Xin 6Add BLAST16
Repeati534 – 549Xin 7Add BLAST16
Repeati572 – 587Xin 8Add BLAST16
Repeati606 – 621Xin 9Add BLAST16
Repeati640 – 655Xin 10Add BLAST16
Repeati677 – 692Xin 11Add BLAST16
Repeati713 – 728Xin 12Add BLAST16
Repeati744 – 759Xin 13Add BLAST16
Repeati782 – 797Xin 14Add BLAST16
Repeati820 – 835Xin 15Add BLAST16
Repeati859 – 874Xin 16Add BLAST16
Repeati892 – 907Xin 17Add BLAST16
Repeati930 – 945Xin 18Add BLAST16
Repeati965 – 980Xin 19Add BLAST16
Repeati1004 – 1019Xin 20Add BLAST16
Repeati1040 – 1055Xin 21Add BLAST16
Repeati1077 – 1092Xin 22Add BLAST16
Repeati1115 – 1130Xin 23Add BLAST16
Repeati1152 – 1167Xin 24Add BLAST16
Repeati1186 – 1201Xin 25Add BLAST16
Repeati1217 – 1232Xin 26Add BLAST16
Repeati1254 – 1269Xin 27Add BLAST16
Repeati1289 – 1304Xin 28Add BLAST16

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2303 – 2328Sequence analysisAdd BLAST26
Coiled coili2696 – 2724Sequence analysisAdd BLAST29
Coiled coili2751 – 2777Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi222 – 226Poly-Pro5
Compositional biasi2052 – 2137Pro-richAdd BLAST86

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Xin repeats bind F-actin.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Xin family.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502SF50, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q71LX6

Database of Orthologous Groups

More...
OrthoDBi
30028at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q71LX6

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012510, Actin-binding_Xin_repeat
IPR030072, XIRP1/XIRP2
IPR030107, XIRP2

The PANTHER Classification System

More...
PANTHERi
PTHR22591, PTHR22591, 1 hit
PTHR22591:SF1, PTHR22591:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08043, Xin, 19 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51389, XIN, 28 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q71LX6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARYQAAVSR GDTRSFSANV MEESDLCTVP GGLAKMKRQF EKDEMTSTCN
60 70 80 90 100
AFSEYQYQHE SRSEQEAIHN RQEIRRNEEE VSKGHRTDVF KAEMMSHLEK
110 120 130 140 150
HTEETNQASQ FRQYVQETVI DTPEDEEIPK VSTKILKEQF EKTAQENFLY
160 170 180 190 200
SDKETTTPAK CIKIENDSEE TLKPSSAMGT SSYTSARQSK ETSTSSYSNH
210 220 230 240 250
SLTSTILAQE KGTPSGKMEE FPPPPPDVFQ TPMDVTAFSQ SPEFPSPPRR
260 270 280 290 300
LPMPRDVYSK QRNLYELNRL YRHIHPELRK NLEKDYISEV SEIVSSHINS
310 320 330 340 350
GNSISAGVQQ ARYVFENTND SSQKDLSSER ENLEWDEILK GEVQSIRWIF
360 370 380 390 400
ENQPLDSINQ GFTDEAYTSK GIADQELIAG GDVKYTTWMF ETQPIDALGV
410 420 430 440 450
PSAGTEENTE KIPELAKGDV CTARWMFETR PLDSMNKMHE WEDETASTFI
460 470 480 490 500
KDITGGDVKT VRYMFETQQL DQLGQLHSVD EMNLLQLRSE LKEIKGNVKR
510 520 530 540 550
SIKCFETQPL YVIRDGSGQM LEIKTVQRED IEKGDVRTAR WMFETQPLDT
560 570 580 590 600
IKQDITEIKV VRGISMEENV KGEVGRARWL FETQPLEKIK EESGEAVLKT
610 620 630 640 650
EAVVGIDVSK KCWMFETQPL DTLKQSPDTE SVSPEERIGG DVKTTKHLLE
660 670 680 690 700
TLPIEALKDS PDVGKLQKIT ASEEEKGDVK HQKWVFETQR LEDIREDKKE
710 720 730 740 750
YTQTVKLEAV DRGHVKNYTH IFESNNLIKV DASHQIEVEG VTRGTVELNK
760 770 780 790 800
SLFETTPLYA IQDHLGKYHQ VKTVQQEEIV RGDVRSCRWL FETRPIDQFD
810 820 830 840 850
ESLHKFQIIR GISAQEIQAG NVKSARWLFE TQPLDSIKYF SNVEETDSKT
860 870 880 890 900
EQSTDIVKGD VKTCKWLFET QPMESLYEKA SLMTNSEDIH KGDVRTCMWL
910 920 930 940 950
FETQPLDAIK NDSEATVKLQ TVKQEEIQGG DVRTACLLFE TENLDNIQGG
960 970 980 990 1000
EGKETKPVEM DIESGDVSGM KYKFENQSLD SISCSSENVL NKIKTLKIED
1010 1020 1030 1040 1050
IQKGNVLNCR WLFENQPIDM IKENQEGDGL VKTVTDIQGG DVRKGCFIFE
1060 1070 1080 1090 1100
TFSLDEIKDE SDVISTRQTN TEEVIKGDVK SYKMLFETQP LYAIQDQEGF
1110 1120 1130 1140 1150
YHEVTTVKKE ETIHGDVRGT RWLFETKPLD SINASEDVYI IKSVTQEDIQ
1160 1170 1180 1190 1200
KGDVSSVRYR FETQPLDMIS DKSHNIMPTI DHIQGGNVQM NKQLFESEGG
1210 1220 1230 1240 1250
DKKNYVRTVS INEIQKGNVK TSTWLFETHS IDELGEVSTY ENIKTVTQED
1260 1270 1280 1290 1300
VQKGDVKQAV WLFENQTLDS IKELDESDTK ITKEEIPPSD VKTTTWLFET
1310 1320 1330 1340 1350
TPIHEFNETR IEKEEIIGKS IKETLEDLYS QRVVEAPGII IEADEVGDVR
1360 1370 1380 1390 1400
MAKYKLMNQR TPEIQKEEVI RADLGNIMMN LLSQRDCTKK EIFISEEEKG
1410 1420 1430 1440 1450
NVNFTKTQLL NRSMEFHAEK EEIVRGDVKQ AIQKLFSEER CAKRGILIQE
1460 1470 1480 1490 1500
DEKGDVNMTI YCLLHENAGD KTKREDILGG DVRRTIHNLL SSASNDKISE
1510 1520 1530 1540 1550
RTKIDASERG NVQFFTTCIE TGALDYLKQL QTGSNETLTA RKQEGEEEII
1560 1570 1580 1590 1600
GGDVEGTKFL LKKRQSSIER TVSETDIIPG DVRNTVKVFM TEPQSASFKT
1610 1620 1630 1640 1650
AKEEIVKGDL KSTLNSLNQA MNQKVVAKTE DIMKDDKAAI LKSLKESGGR
1660 1670 1680 1690 1700
QKEHKQSASI SSDIGQAIEC LEKATNTRTE ILKKELILDD LKTSLRSLKE
1710 1720 1730 1740 1750
EQYSFKEVGK QGMVKDVLGF SERQELGIHP AAVQREKKSL LQPVPGPCEP
1760 1770 1780 1790 1800
AIRQQAGPGP LDEATQKSCH RSLTEERTEA NLPKAPKGTV KIVIDREQNN
1810 1820 1830 1840 1850
DALEKSLRKM SNSEHRAMKN VLDMGDRRGV WTESKECLCS DDHMSKYVSA
1860 1870 1880 1890 1900
SMSRKKSLKT KESENVRESK DDVSSTQSVD KTFRKQQTQN CELGKDHQKS
1910 1920 1930 1940 1950
QFQDSYAKNQ KNTQNISMSA ETQSYRPDPT QHPVSNPAGE TLEMTRDFQK
1960 1970 1980 1990 2000
QALIRQEKQN SNKDMRKNDM GLQPLPVGKD AHSAPGVTVS GKNHKRTQAP
2010 2020 2030 2040 2050
DKKQRIDVCL ESQDFLMKTN TSKELKMAME RSFNPVNLYP DCGVKENEDA
2060 2070 2080 2090 2100
LPPPSPPPPP PSNASSEIEF PLPPPPPIML LPEKNEFPPS SPTEKSRAEL
2110 2120 2130 2140 2150
ESLPTLPLPP PPGDEKSDQE CLPTSLPPPP PTAPSQPAHL LSSSVLEHHS
2160 2170 2180 2190 2200
EAFLQQYSRK ETLDSHQLHS QAKILTGKSP PPTLPKPKLP ERIKAKMSQD
2210 2220 2230 2240 2250
SPSGELERSL SDVEIKTTLS KDQKSSLVAE SREHTEAKQE VFRKSLGRKQ
2260 2270 2280 2290 2300
LSISSANSLS QTVPEIPAPK EKQTAPLVKS HSFPSGSEQQ SPKPYMRKFK
2310 2320 2330 2340 2350
TPLMIAEEKY RQQREELEKQ RRESSCHSII KTETQHRSLS EKEKETELQK
2360 2370 2380 2390 2400
AAEAMSTPRK DSDFTRAQPN LEPKSKAVIA SECSESQLST ASALTVATER
2410 2420 2430 2440 2450
LQHVLAASDD KLTLRREGTQ NSSDTLQSKT ACEINQSHKE CRTEQTFEQH
2460 2470 2480 2490 2500
VEKLPFPQTK PISPSFKVKT IRLPALDHTL TETDLSSERR VKQSEIDVQT
2510 2520 2530 2540 2550
STKEMNKEIK KTEVSTQCDN KQSVAEKYFQ LPKTEKRVTV QMPKDYAAKS
2560 2570 2580 2590 2600
HQSKLQTVPK KHGGLGEFDR GNVLGREGKN QDSSMSSTKE SRVIVERKQE
2610 2620 2630 2640 2650
HLQDQSVPRL VQQKIIGESL DSRVQNFQQT QTQTSRIEHK ELSQPYSEKK
2660 2670 2680 2690 2700
CLRDKDKQQK QVSSNTDDSK QEITQKQSSF SSVRESQQDG EKCAINILEF
2710 2720 2730 2740 2750
LRKREELQQI LSRVKQFEAD SNKSGLKTFQ TLLNIAPVWL ISEEKREYGV
2760 2770 2780 2790 2800
RVAMENNLEK VKEEIIHIKT QAEEMLVHCE HVIRTAMMAS QTGKQKDKPT
2810 2820 2830 2840 2850
NLNEMPLKVS NVNLSSHKGT EQKESKIVEE KLASRQVATH SEAATHNPAK
2860 2870 2880 2890 2900
TYQEAKGDDS KMAPPSLKTR PPSPTFITIE STARRAETST KSELSQSPKN
2910 2920 2930 2940 2950
NSCVEPLPRR PMEHTSRLPR TSTSPSPPRS RSEQLVRLKD TTARLAKGTI
2960 2970 2980 2990 3000
PCSPGTPVPV VEKRSEVVMS PATLRRQIKI ESRGGDSPPT ITIPVSVNHH
3010 3020 3030 3040 3050
VVSGSFRESV DAQEAVKKTE KTETYVHKDK KNSVSSAMPE TESYDAVEII
3060 3070 3080 3090 3100
RKVEGPHLSE HRERFEATNQ TVQMAEHFLN GHENEVNRWF REFENGPVFG
3110 3120 3130 3140 3150
AKTERRAYAN GEINHNMKQE SHTFCKEEFG LESSETANFT GFSYRHPREH
3160 3170 3180 3190 3200
RAKAPATQPR VHSEARALNE HFLSVDAFDS QIVESQVATS SSRSSEAGRS
3210 3220 3230 3240 3250
GFDFKHAPPT YEDVIAGHIL DIADSPTNLR RNFQKTWQES ERVFKSVGYE
3260 3270 3280 3290 3300
TSDAHATEMS RAFQEELAFL SETVGPRQGN LHNLSKDGLS NGVPRSRPAE

FS
Length:3,302
Mass (Da):373,982
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i65EFEFEED1778ECB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1LMC2F1LMC2_RAT
Xin actin-binding repeat-containing...
Xirp2
3,302Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF466694 mRNA Translation: AAQ05020.1

NCBI Reference Sequences

More...
RefSeqi
NP_973718.1, NM_201989.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
311098

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:311098

UCSC genome browser

More...
UCSCi
RGD:1302980, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF466694 mRNA Translation: AAQ05020.1
RefSeqiNP_973718.1, NM_201989.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi259825, 1 interactor
STRINGi10116.ENSRNOP00000048045

PTM databases

iPTMnetiQ71LX6
PhosphoSitePlusiQ71LX6

Proteomic databases

PaxDbiQ71LX6
PRIDEiQ71LX6

Genome annotation databases

GeneIDi311098
KEGGirno:311098
UCSCiRGD:1302980, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
129446
RGDi1302980, Xirp2

Phylogenomic databases

eggNOGiENOG502SF50, Eukaryota
InParanoidiQ71LX6
OrthoDBi30028at2759
PhylomeDBiQ71LX6

Miscellaneous databases

Protein Ontology

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PROi
PR:Q71LX6

Family and domain databases

InterProiView protein in InterPro
IPR012510, Actin-binding_Xin_repeat
IPR030072, XIRP1/XIRP2
IPR030107, XIRP2
PANTHERiPTHR22591, PTHR22591, 1 hit
PTHR22591:SF1, PTHR22591:SF1, 1 hit
PfamiView protein in Pfam
PF08043, Xin, 19 hits
PROSITEiView protein in PROSITE
PS51389, XIN, 28 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiXIRP2_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q71LX6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 71 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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