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Entry version 109 (07 Apr 2021)
Sequence version 2 (03 Apr 2007)
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Protein

Cardiac-enriched FHL2-interacting protein

Gene

CEFIP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q711Q0

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cardiac-enriched FHL2-interacting protein1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CEFIP1 Publication
Synonyms:C10orf71
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26973, C10orf71

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q711Q0

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000177354.11

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
118461

Open Targets

More...
OpenTargetsi
ENSG00000177354

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134920715

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q711Q0, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C10orf71

Domain mapping of disease mutations (DMDM)

More...
DMDMi
143955302

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002829791 – 1435Cardiac-enriched FHL2-interacting proteinAdd BLAST1435

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei120PhosphothreonineCombined sources1
Modified residuei323PhosphoserineCombined sources1
Modified residuei470PhosphoserineCombined sources1
Modified residuei816PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q711Q0

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q711Q0

PeptideAtlas

More...
PeptideAtlasi
Q711Q0

PRoteomics IDEntifications database

More...
PRIDEi
Q711Q0

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
68588 [Q711Q0-1]
68589 [Q711Q0-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q711Q0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q711Q0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the heart and skeletal muscle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000177354, Expressed in skeletal muscle tissue and 98 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q711Q0, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000177354, Group enriched (skeletal muscle, tongue)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FHL2.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
125609, 7 interactors

Protein interaction database and analysis system

More...
IntActi
Q711Q0, 6 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000363259

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q711Q0, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q711Q0

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QVE3, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111333

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_255771_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q711Q0

Identification of Orthologs from Complete Genome Data

More...
OMAi
HYSPPFN

Database of Orthologous Groups

More...
OrthoDBi
416362at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q711Q0

TreeFam database of animal gene trees

More...
TreeFami
TF336978

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR027838, DUF4585

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15232, DUF4585, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q711Q0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMQGNKKCTD AFSDSSSIGS VLDDADREVS SLTDRAFRSL CISEDTSFHD
60 70 80 90 100
SYLAVSPDIT RQVFGTFHQR TVGHTQRKSG IWSQLPSQGT EHSGWAATFQ
110 120 130 140 150
QLPKYVQGEE KYPKTSPPPT PVQRRLEVPV SGLRSSNKPV SKVSTLIKSF
160 170 180 190 200
DRTESQRCES RPTASKPPAL KNPPKFAPLP ENSVNFCFDS AFLTVRRVPA
210 220 230 240 250
EVSNTHQNSY QPGRKHGEQE SSKNPEMACH GSSSFLPAAN DTATLCESKF
260 270 280 290 300
PSPHHKPVTG EPGRGKGTFL HSENSAFESW NAHQPKLLER KDTAGTVPES
310 320 330 340 350
KAPKHYGDTT LLREPCPPER TVSPCQVQAS CSQEENRLAA GALSTSIPWG
360 370 380 390 400
CRDPGAQVFA VEGKAPSSQP DSQEKPAQPP WRKPKTGKKG KESLQDTLEE
410 420 430 440 450
KTQTNQRGPP LYTKHNPQEQ FSENNALDLP VEPNEHYDPP FNISKLLTPI
460 470 480 490 500
IPSKHALDSA DSQPAERTPS PPGQLNGYQE KEPSECQSRD SYKSKAPSLL
510 520 530 540 550
FNLKDVRKRV KSTYSSSPLL KVLDEKTRGK VDGKQEPVSN GVILPNGLEE
560 570 580 590 600
SPPNELSKER PADDPTASHI NPQKDPTADP SEPSADSYLT LSTAPTIAKA
610 620 630 640 650
PFYVNGEAAE RSSYENKEVE GELEMGPAGS SWCPDSREHR PRKHLSLRLC
660 670 680 690 700
NRDPEPGGAT EKMKTHQLEN GLSRSVSQET EPEREAGLQN THLNQKFFPG
710 720 730 740 750
PLSPEEEDVF YSDSQSDFMP SLKGKAKFST SSSDQSFASF DDQQKMWFTE
760 770 780 790 800
NQREDRRKDV SAGDSQKDEK ENVMRKDELQ YCALSNGHAC LENRSQGEAL
810 820 830 840 850
QRERESVSGG RTRKASAEEA NFRGSWIGEN KGTTFSQAKD LTPSPSSASN
860 870 880 890 900
RHMLFTIKDN TLRATPVIKP IMLPLLRTMS LEDSLSSGHK EEELPRPEWG
910 920 930 940 950
EDPGFCAPEN QDILGTSTPT NTRGTRVKCM ANEVMEDPGQ GSSMARMEAS
960 970 980 990 1000
QPAPKGNFPS MPLVGEGDRV KAPPDAAPGL VASNCKSGSA DSGKLAAPWH
1010 1020 1030 1040 1050
IPTIALPEGD IEDQPPPWQP ENCWEEQTPG FKSHFLSTPR AGPPGRRLVP
1060 1070 1080 1090 1100
SERANSPNPG SPGESSACSP AASNIWEESS QAPGGPELLP EEPNQASPWA
1110 1120 1130 1140 1150
SSSPARVTRR EDLTHALVWE GGSDPLLELS AEDLRTLSPR GSLLDVATSP
1160 1170 1180 1190 1200
AGTSGRLELP AQLERTASKP PAVPPKTEKA LRRAKKLASK RRKTDQAQEK
1210 1220 1230 1240 1250
HGESQEGKPC PEDLEQTQQR PLCPRERPRH NFPVVRSLPP PVHRHSVSGF
1260 1270 1280 1290 1300
SEPVGRRPGG PQSLTPLPAY PATQKVLQDP QSGEYFVFDL PLQVKIKTFY
1310 1320 1330 1340 1350
DPETGKYVKV SIPSSEGASP EPPPPDALAA PYVLYPGFQP VPVTALMPLR
1360 1370 1380 1390 1400
CSSQLSAPTF LRQGPRASAA RARTQSVHES GLQLDPGPHG DCTPHSAGQR
1410 1420 1430
PHGPPQSPGE EGVEAPGLGI ISTDDLEDFA TEGIS
Length:1,435
Mass (Da):156,477
Last modified:April 3, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD120E1F57AF30CEE
GO
Isoform 3 (identifier: Q711Q0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     693-719: LNQKFFPGPLSPEEEDVFYSDSQSDFM → THTHTHTHTHDHQHILSLFRSIKSRRQ
     720-1435: Missing.

Show »
Length:719
Mass (Da):79,378
Checksum:iABE1B529179AF351
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAC85340 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti339A → E in AL833265 (PubMed:17974005).Curated1
Sequence conflicti339A → E in AAI26414 (PubMed:15489334).Curated1
Sequence conflicti382R → G in AL833265 (PubMed:17974005).Curated1
Sequence conflicti503L → H in AL833265 (PubMed:17974005).Curated1
Sequence conflicti663M → V in AK127811 (PubMed:14702039).Curated1
Sequence conflicti870 – 871PI → RL in CAC85340 (Ref. 5) Curated2
Sequence conflicti1269A → T in AL833265 (PubMed:17974005).Curated1
Sequence conflicti1281Q → H in CAC85340 (Ref. 5) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_031441208N → K1 PublicationCorresponds to variant dbSNP:rs4838383Ensembl.1
Natural variantiVAR_061604320R → L2 PublicationsCorresponds to variant dbSNP:rs56206226Ensembl.1
Natural variantiVAR_061605461D → A2 PublicationsCorresponds to variant dbSNP:rs45554335Ensembl.1
Natural variantiVAR_061606522V → G. Corresponds to variant dbSNP:rs61453891EnsemblClinVar.1
Natural variantiVAR_031442666H → Q. Corresponds to variant dbSNP:rs10857469Ensembl.1
Natural variantiVAR_059608698F → S1 PublicationCorresponds to variant dbSNP:rs7921186Ensembl.1
Natural variantiVAR_059609741D → G. Corresponds to variant dbSNP:rs11101093Ensembl.1
Natural variantiVAR_059610883D → N1 PublicationCorresponds to variant dbSNP:rs12217617Ensembl.1
Natural variantiVAR_059611958F → Y. Corresponds to variant dbSNP:rs10857470Ensembl.1
Natural variantiVAR_0596121084G → A. Corresponds to variant dbSNP:rs11101094Ensembl.1
Natural variantiVAR_0596131254V → I. Corresponds to variant dbSNP:rs11101095Ensembl.1
Natural variantiVAR_0596141337G → S. Corresponds to variant dbSNP:rs10857472Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_024267693 – 719LNQKF…QSDFM → THTHTHTHTHDHQHILSLFR SIKSRRQ in isoform 3. 2 PublicationsAdd BLAST27
Alternative sequenceiVSP_024268720 – 1435Missing in isoform 3. 2 PublicationsAdd BLAST716

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK127811 mRNA No translation available.
AL833265 mRNA No translation available.
AC027674 Genomic DNA No translation available.
BC126413 mRNA Translation: AAI26414.1
AJ311357 mRNA Translation: CAC85340.1 Frameshift.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS44387.1 [Q711Q0-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001128668.1, NM_001135196.1 [Q711Q0-1]
XP_005269533.1, XM_005269476.4 [Q711Q0-1]
XP_005269534.1, XM_005269477.3 [Q711Q0-1]
XP_005269535.1, XM_005269478.4 [Q711Q0-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000374144; ENSP00000363259; ENSG00000177354 [Q711Q0-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
118461

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:118461

UCSC genome browser

More...
UCSCi
uc021pqa.3, human [Q711Q0-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK127811 mRNA No translation available.
AL833265 mRNA No translation available.
AC027674 Genomic DNA No translation available.
BC126413 mRNA Translation: AAI26414.1
AJ311357 mRNA Translation: CAC85340.1 Frameshift.
CCDSiCCDS44387.1 [Q711Q0-1]
RefSeqiNP_001128668.1, NM_001135196.1 [Q711Q0-1]
XP_005269533.1, XM_005269476.4 [Q711Q0-1]
XP_005269534.1, XM_005269477.3 [Q711Q0-1]
XP_005269535.1, XM_005269478.4 [Q711Q0-1]

3D structure databases

SMRiQ711Q0
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi125609, 7 interactors
IntActiQ711Q0, 6 interactors
STRINGi9606.ENSP00000363259

PTM databases

iPTMnetiQ711Q0
PhosphoSitePlusiQ711Q0

Genetic variation databases

BioMutaiC10orf71
DMDMi143955302

Proteomic databases

MassIVEiQ711Q0
PaxDbiQ711Q0
PeptideAtlasiQ711Q0
PRIDEiQ711Q0
ProteomicsDBi68588 [Q711Q0-1]
68589 [Q711Q0-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
50031, 22 antibodies

The DNASU plasmid repository

More...
DNASUi
118461

Genome annotation databases

EnsembliENST00000374144; ENSP00000363259; ENSG00000177354 [Q711Q0-1]
GeneIDi118461
KEGGihsa:118461
UCSCiuc021pqa.3, human [Q711Q0-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
118461
DisGeNETi118461

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C10orf71
HGNCiHGNC:26973, C10orf71
HPAiENSG00000177354, Group enriched (skeletal muscle, tongue)
neXtProtiNX_Q711Q0
OpenTargetsiENSG00000177354
PharmGKBiPA134920715
VEuPathDBiHostDB:ENSG00000177354.11

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502QVE3, Eukaryota
GeneTreeiENSGT00730000111333
HOGENOMiCLU_255771_0_0_1
InParanoidiQ711Q0
OMAiHYSPPFN
OrthoDBi416362at2759
PhylomeDBiQ711Q0
TreeFamiTF336978

Enzyme and pathway databases

PathwayCommonsiQ711Q0

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
118461, 4 hits in 975 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
C10orf71, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
118461
PharosiQ711Q0, Tdark

Protein Ontology

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PROi
PR:Q711Q0
RNActiQ711Q0, protein

Gene expression databases

BgeeiENSG00000177354, Expressed in skeletal muscle tissue and 98 other tissues
GenevisibleiQ711Q0, HS

Family and domain databases

InterProiView protein in InterPro
IPR027838, DUF4585
PfamiView protein in Pfam
PF15232, DUF4585, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCEFIP_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q711Q0
Secondary accession number(s): A0AVL8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: April 3, 2007
Last modified: April 7, 2021
This is version 109 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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