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Protein

Protein unc-93 homolog A

Gene

Unc93a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein unc-93 homolog A
Short name:
Unc-93A
Gene namesi
Name:Unc93a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1933250 Unc93a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Transmembranei69 – 89HelicalSequence analysisAdd BLAST21
Transmembranei90 – 110HelicalSequence analysisAdd BLAST21
Transmembranei140 – 160HelicalSequence analysisAdd BLAST21
Transmembranei202 – 222HelicalSequence analysisAdd BLAST21
Transmembranei258 – 275HelicalSequence analysisAdd BLAST18
Transmembranei286 – 306HelicalSequence analysisAdd BLAST21
Transmembranei321 – 341HelicalSequence analysisAdd BLAST21
Transmembranei345 – 365HelicalSequence analysisAdd BLAST21
Transmembranei390 – 410HelicalSequence analysisAdd BLAST21
Transmembranei412 – 432HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001900371 – 458Protein unc-93 homolog AAdd BLAST458

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi190N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ710D3
PRIDEiQ710D3

Expressioni

Gene expression databases

BgeeiENSMUSG00000067049 Expressed in 14 organ(s), highest expression level in colon
CleanExiMM_UNC93A

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000082032

Structurei

3D structure databases

ProteinModelPortaliQ710D3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the unc-93 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3097 Eukaryota
ENOG410XTFP LUCA
GeneTreeiENSGT00530000063359
HOGENOMiHOG000007567
HOVERGENiHBG080785
InParanoidiQ710D3
OMAiKRFGCKW
OrthoDBiEOG091G07EN
PhylomeDBiQ710D3
TreeFamiTF314905

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR010291 Ion_channel_UNC-93
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF05978 UNC-93, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit

Sequencei

Sequence statusi: Complete.

Q710D3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MERSLKNVLV VSCGFLLLFT AYGGLQNLQS SLYSEQGLGV ATLSTLYASV
60 70 80 90 100
LLSSMFLPPI LIKKCGCKWT IVGSMCCYVV FSLGNFHANW YTLIPTSILL
110 120 130 140 150
GLGAAPLWSA QGTYLTTMGN LQAEKVGKLG KDVVNQYFGI FFLVFQSSGV
160 170 180 190 200
WGNLISSLVF GKMSMQEAIP EEQLMSCGAK DCLMGPAATN STHHPSQQLI
210 220 230 240 250
YTLLGIYTGC GVLAILLVAV FLESLEDKLE NEGERRPRPP PLWSTLLSTF
260 270 280 290 300
MLFRDKRLCL LMFLPLYSGF QQEFLSGEYT KSYVTCALGI HFVGYVMICF
310 320 330 340 350
SAMTALCSLL YGKISKYTGR AALYALGAAI HFSCIVVFLL WHPNTNQLPV
360 370 380 390 400
FFVLSGLWGM SDAVWQTQNN ALFGVLFEEN KEPAFANYRL GEAIGFVIAF
410 420 430 440 450
GYSSFLCVST KLYILLGVLS LAMVGYGTVE YLEVKAASKV LGAEKKNQAE

EEEMKTKI
Length:458
Mass (Da):50,370
Last modified:July 5, 2004 - v1
Checksum:iAB405CCA4E1BA9A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ422143 mRNA Translation: CAD19523.1
CCDSiCCDS28402.1
RefSeqiNP_954860.1, NM_199252.2
XP_011244517.1, XM_011246215.2
XP_011244518.1, XM_011246216.1
XP_011244519.1, XM_011246217.2
XP_011244520.1, XM_011246218.2
UniGeneiMm.390935

Genome annotation databases

EnsembliENSMUST00000084966; ENSMUSP00000082032; ENSMUSG00000067049
GeneIDi381058
KEGGimmu:381058
UCSCiuc008amc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ422143 mRNA Translation: CAD19523.1
CCDSiCCDS28402.1
RefSeqiNP_954860.1, NM_199252.2
XP_011244517.1, XM_011246215.2
XP_011244518.1, XM_011246216.1
XP_011244519.1, XM_011246217.2
XP_011244520.1, XM_011246218.2
UniGeneiMm.390935

3D structure databases

ProteinModelPortaliQ710D3
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000082032

Proteomic databases

PaxDbiQ710D3
PRIDEiQ710D3

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000084966; ENSMUSP00000082032; ENSMUSG00000067049
GeneIDi381058
KEGGimmu:381058
UCSCiuc008amc.1 mouse

Organism-specific databases

CTDi54346
MGIiMGI:1933250 Unc93a

Phylogenomic databases

eggNOGiKOG3097 Eukaryota
ENOG410XTFP LUCA
GeneTreeiENSGT00530000063359
HOGENOMiHOG000007567
HOVERGENiHBG080785
InParanoidiQ710D3
OMAiKRFGCKW
OrthoDBiEOG091G07EN
PhylomeDBiQ710D3
TreeFamiTF314905

Miscellaneous databases

PROiPR:Q710D3
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000067049 Expressed in 14 organ(s), highest expression level in colon
CleanExiMM_UNC93A

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR010291 Ion_channel_UNC-93
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
PfamiView protein in Pfam
PF05978 UNC-93, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUN93A_MOUSE
AccessioniPrimary (citable) accession number: Q710D3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 5, 2004
Last modified: November 7, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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