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Protein

Protein FRA10AC1

Gene

FRA10AC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Expansion of a polymorphic CGG repeat within the 5'-UTR of this gene FRA10AC1 may be the cause of folate-sensitive fragile site FRA10A expression which is characterized by chromosomal breakage under specific cell culture conditions. No distinct phenotype has been associated with expression of FRA10A. Nevertheless, some studies have proposed that this fragile site expression might be associated with mental retardation, tumorigenesis, or neurological disorders. However, these associations can be attributed to ascertainment bias.

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FRA10AC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FRA10AC1
Synonyms:C10orf4
ORF Names:PRO2972
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000148690.11

Human Gene Nomenclature Database

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HGNCi
HGNC:1162 FRA10AC1

Online Mendelian Inheritance in Man (OMIM)

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MIMi
608866 gene+phenotype

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q70Z53

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

MIMi608866 gene+phenotype

Open Targets

More...
OpenTargetsi
ENSG00000148690

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25476

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FRA10AC1

Domain mapping of disease mutations (DMDM)

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DMDMi
296439361

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000871481 – 315Protein FRA10AC1Add BLAST315

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei9PhosphoserineBy similarity1
Modified residuei12PhosphoserineCombined sources1
Modified residuei36N6-acetyllysineBy similarity1
Modified residuei251PhosphoserineCombined sources1
Modified residuei252PhosphoserineCombined sources1
Modified residuei278PhosphoserineCombined sources1
Modified residuei283PhosphoserineBy similarity1
Modified residuei285PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q70Z53

MaxQB - The MaxQuant DataBase

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MaxQBi
Q70Z53

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
Q70Z53

PeptideAtlas

More...
PeptideAtlasi
Q70Z53

PRoteomics IDEntifications database

More...
PRIDEi
Q70Z53

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68583
68584 [Q70Z53-2]
68585 [Q70Z53-3]
68586 [Q70Z53-4]
68587 [Q70Z53-5]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q70Z53

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q70Z53

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed with higher expression in brain, heart, skeletal muscle, kidney and liver.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148690 Expressed in 203 organ(s), highest expression level in caudate nucleus

CleanEx database of gene expression profiles

More...
CleanExi
HS_C10orf4

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q70Z53 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039204

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
125626, 38 interactors

Protein interaction database and analysis system

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IntActi
Q70Z53, 26 interactors

Molecular INTeraction database

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MINTi
Q70Z53

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000360488

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q70Z53

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi129 – 269Lys-richAdd BLAST141

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1297 Eukaryota
ENOG410YN91 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000017833

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG059566

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
Q70Z53

KEGG Orthology (KO)

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KOi
K13121

Identification of Orthologs from Complete Genome Data

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OMAi
PECSFKL

Database of Orthologous Groups

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OrthoDBi
EOG091G115J

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q70Z53

TreeFam database of animal gene trees

More...
TreeFami
TF323667

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR019129 Folate-sensitive_fs_Fra10Ac1

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09725 Fra10Ac1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (5)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 5 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q70Z53-1) [UniParc]FASTAAdd to basket
Also known as: FRA10AC1-1

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHGHGGYDSD FSDDERCGES SKRKKRTVED DLLLQKPFQK EKHGKVAHKQ
60 70 80 90 100
VAAELLDREE ARNRRFHLIA MDAYQRHTKF VNDYILYYGG KKEDFKRLGE
110 120 130 140 150
NDKTDLDVIR ENHRFLWNEE DEMDMTWEKR LAKKYYDKLF KEYCIADLSK
160 170 180 190 200
YKENKFGFRW RVEKEVISGK GQFFCGNKYC DKKEGLKSWE VNFGYIEHGE
210 220 230 240 250
KRNALVKLRL CQECSIKLNF HHRRKEIKSK KRKDKTKKDC EESSHKKSRL
260 270 280 290 300
SSAEEASKKK DKGHSSSKKS EDSLLRNSDE EESASESELW KGPLPETDEK
310
SQEEEFDEYF QDLFL
Length:315
Mass (Da):37,548
Last modified:May 18, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i418963E63A34EE9E
GO
Isoform 2 (identifier: Q70Z53-2) [UniParc]FASTAAdd to basket
Also known as: FRA10AC1-2

The sequence of this isoform differs from the canonical sequence as follows:
     276-276: R → N
     277-315: Missing.

Show »
Length:276
Mass (Da):32,896
Checksum:iC49F4A55F0E34BB9
GO
Isoform 3 (identifier: Q70Z53-3) [UniParc]FASTAAdd to basket
Also known as: FRA10AC1-3.1

The sequence of this isoform differs from the canonical sequence as follows:
     276-315: RNSDEEESAS...FDEYFQDLFL → RRMLEELQMF...LSANVTTLKL

Show »
Length:315
Mass (Da):37,486
Checksum:iEDC0813749CAF011
GO
Isoform 4 (identifier: Q70Z53-4) [UniParc]FASTAAdd to basket
Also known as: FRA10AC1-3.2

The sequence of this isoform differs from the canonical sequence as follows:
     276-292: RNSDEEESASESELWKG → KTYFVGLLSESNEKTYM
     293-315: Missing.

Show »
Length:292
Mass (Da):34,774
Checksum:i86E2A92B6C2432B4
GO
Isoform 5 (identifier: Q70Z53-5) [UniParc]FASTAAdd to basket
Also known as: FRA10AC1-3.3

The sequence of this isoform differs from the canonical sequence as follows:
     276-315: RNSDEEESAS...FDEYFQDLFL → NGVMLFHPGW...NNHYWRGVVC

Show »
Length:313
Mass (Da):36,919
Checksum:iAF49C271FE914EAD
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAK55529 differs from that shown. Chimeric cDNA.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti81V → I in CAD24470 (PubMed:15203205).Curated1
Sequence conflicti81V → I in CAD24471 (PubMed:15203205).Curated1
Sequence conflicti81V → I in CAD24472 (PubMed:15203205).Curated1
Sequence conflicti81V → I in CAD24473 (PubMed:15203205).Curated1
Sequence conflicti81V → I in CAD24474 (PubMed:15203205).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_02323716R → HCombined sources2 PublicationsCorresponds to variant dbSNP:rs726817Ensembl.1
Natural variantiVAR_02323878T → R2 PublicationsCorresponds to variant dbSNP:rs2275438Ensembl.1
Natural variantiVAR_056872251S → F. Corresponds to variant dbSNP:rs11187583Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_015123276 – 315RNSDE…QDLFL → RRMLEELQMFTWEKSERMGG KRLIIIIGEELSANVTTLKL in isoform 3. 1 PublicationAdd BLAST40
Alternative sequenceiVSP_015124276 – 315RNSDE…QDLFL → NGVMLFHPGWSAVARSQLTA APASQVQTNNHYWRGVVC in isoform 5. 1 PublicationAdd BLAST40
Alternative sequenceiVSP_015125276 – 292RNSDE…ELWKG → KTYFVGLLSESNEKTYM in isoform 4. 1 PublicationAdd BLAST17
Alternative sequenceiVSP_015126276R → N in isoform 2. 1 Publication1
Alternative sequenceiVSP_015127277 – 315Missing in isoform 2. 1 PublicationAdd BLAST39
Alternative sequenceiVSP_015128293 – 315Missing in isoform 4. 1 PublicationAdd BLAST23

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ431721 mRNA Translation: CAD24470.1
AJ431722 mRNA Translation: CAD24471.1
AJ431723 mRNA Translation: CAD24472.1
AJ431724 mRNA Translation: CAD24473.1
AJ431725 mRNA Translation: CAD24474.1
AK090955 mRNA Translation: BAC03556.1
AL157396 Genomic DNA No translation available.
BC018007 mRNA Translation: AAH18007.1
AF305826 mRNA Translation: AAK55529.1 Sequence problems.

The Consensus CDS (CCDS) project

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CCDSi
CCDS7430.1 [Q70Z53-1]

NCBI Reference Sequences

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RefSeqi
NP_001334641.1, NM_001347712.1 [Q70Z53-1]
NP_001334642.1, NM_001347713.1 [Q70Z53-1]
NP_001334643.1, NM_001347714.1 [Q70Z53-1]
NP_001334644.1, NM_001347715.1 [Q70Z53-1]
NP_660289.2, NM_145246.4 [Q70Z53-1]
XP_016871150.1, XM_017015661.1

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.586650

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359204; ENSP00000360488; ENSG00000148690 [Q70Z53-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
118924

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:118924

UCSC genome browser

More...
UCSCi
uc001kiz.2 human [Q70Z53-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ431721 mRNA Translation: CAD24470.1
AJ431722 mRNA Translation: CAD24471.1
AJ431723 mRNA Translation: CAD24472.1
AJ431724 mRNA Translation: CAD24473.1
AJ431725 mRNA Translation: CAD24474.1
AK090955 mRNA Translation: BAC03556.1
AL157396 Genomic DNA No translation available.
BC018007 mRNA Translation: AAH18007.1
AF305826 mRNA Translation: AAK55529.1 Sequence problems.
CCDSiCCDS7430.1 [Q70Z53-1]
RefSeqiNP_001334641.1, NM_001347712.1 [Q70Z53-1]
NP_001334642.1, NM_001347713.1 [Q70Z53-1]
NP_001334643.1, NM_001347714.1 [Q70Z53-1]
NP_001334644.1, NM_001347715.1 [Q70Z53-1]
NP_660289.2, NM_145246.4 [Q70Z53-1]
XP_016871150.1, XM_017015661.1
UniGeneiHs.586650

3D structure databases

ProteinModelPortaliQ70Z53
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125626, 38 interactors
IntActiQ70Z53, 26 interactors
MINTiQ70Z53
STRINGi9606.ENSP00000360488

PTM databases

iPTMnetiQ70Z53
PhosphoSitePlusiQ70Z53

Polymorphism and mutation databases

BioMutaiFRA10AC1
DMDMi296439361

Proteomic databases

EPDiQ70Z53
MaxQBiQ70Z53
PaxDbiQ70Z53
PeptideAtlasiQ70Z53
PRIDEiQ70Z53
ProteomicsDBi68583
68584 [Q70Z53-2]
68585 [Q70Z53-3]
68586 [Q70Z53-4]
68587 [Q70Z53-5]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
118924
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359204; ENSP00000360488; ENSG00000148690 [Q70Z53-1]
GeneIDi118924
KEGGihsa:118924
UCSCiuc001kiz.2 human [Q70Z53-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
118924
EuPathDBiHostDB:ENSG00000148690.11

GeneCards: human genes, protein and diseases

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GeneCardsi
FRA10AC1

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0009048
HGNCiHGNC:1162 FRA10AC1
HPAiHPA039204
MIMi608866 gene+phenotype
neXtProtiNX_Q70Z53
OpenTargetsiENSG00000148690
PharmGKBiPA25476

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1297 Eukaryota
ENOG410YN91 LUCA
GeneTreeiENSGT00390000017833
HOVERGENiHBG059566
InParanoidiQ70Z53
KOiK13121
OMAiPECSFKL
OrthoDBiEOG091G115J
PhylomeDBiQ70Z53
TreeFamiTF323667

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FRA10AC1 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
C10orf4

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
118924

Protein Ontology

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PROi
PR:Q70Z53

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000148690 Expressed in 203 organ(s), highest expression level in caudate nucleus
CleanExiHS_C10orf4
GenevisibleiQ70Z53 HS

Family and domain databases

InterProiView protein in InterPro
IPR019129 Folate-sensitive_fs_Fra10Ac1
PfamiView protein in Pfam
PF09725 Fra10Ac1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF10C1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70Z53
Secondary accession number(s): C9JCR4
, C9JCR5, C9JMY4, Q70Z49, Q70Z50, Q70Z51, Q70Z52, Q8N293, Q8WVH5, Q96JQ8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 16, 2005
Last sequence update: May 18, 2010
Last modified: November 7, 2018
This is version 124 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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