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Entry version 123 (08 May 2019)
Sequence version 1 (05 Jul 2004)
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Protein

von Willebrand factor A domain-containing protein 2

Gene

Vwa2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • identical protein binding Source: MGI

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
von Willebrand factor A domain-containing protein 2
Alternative name(s):
A domain-containing protein similar to matrilin and collagen
Short name:
AMACO
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Vwa2
Synonyms:Amaco
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2684334 Vwa2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500007039724 – 791von Willebrand factor A domain-containing protein 2Add BLAST768

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi146N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi298 ↔ 309PROSITE-ProRule annotation
Disulfide bondi303 ↔ 319PROSITE-ProRule annotation
Disulfide bondi321 ↔ 331PROSITE-ProRule annotation
Disulfide bondi715 ↔ 726PROSITE-ProRule annotation
Disulfide bondi720 ↔ 735PROSITE-ProRule annotation
Disulfide bondi737 ↔ 746PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q70UZ7

PRoteomics IDEntifications database

More...
PRIDEi
Q70UZ7

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q70UZ7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in uterus, kidney, and skin. Also detected in intestine and lung of adult mice, and in calvaria, femur, brain, heart, intestine, skeletal muscle, and lung of newborn mice.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

First detected at days 7.5-8 dpc, when it is weakly expressed around the developing mesodermal cells. At day 10.5 dpc it is detected in the heart and the condensing somites, and at day 14.5 dpc it is present in the choroid plexus, the cochlea, the terminal bronchii of the lung, the heart, the skin, and in the cartilage primordium of the developing skeleton as well as in the interdigital spaces. Strong staining is seen in the condensed mesenchyme forming the edge of the developing teeth budding into the branchial arch and coinciding with the basement membrane that underlies the stratified squamous epithelia in the oral cavity.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000025082 Expressed in 73 organ(s), highest expression level in ear vesicle

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q70UZ7 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms monomers and multimers.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000026068

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q70UZ7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini51 – 221VWFA 1PROSITE-ProRule annotationAdd BLAST171
Domaini295 – 332EGF-like 1PROSITE-ProRule annotationAdd BLAST38
Domaini342 – 516VWFA 2PROSITE-ProRule annotationAdd BLAST175
Domaini530 – 704VWFA 3PROSITE-ProRule annotationAdd BLAST175
Domaini711 – 747EGF-like 2PROSITE-ProRule annotationAdd BLAST37

Keywords - Domaini

EGF-like domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3544 Eukaryota
ENOG410XNMM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159040

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154835

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q70UZ7

Identification of Orthologs from Complete Genome Data

More...
OMAi
AASKMMW

Database of Orthologous Groups

More...
OrthoDBi
350336at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q70UZ7

TreeFam database of animal gene trees

More...
TreeFami
TF318242

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.410, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR030755 VWA2
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR24020:SF37 PTHR24020:SF37, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00008 EGF, 2 hits
PF00092 VWA, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 2 hits
SM00179 EGF_CA, 2 hits
SM00327 VWA, 3 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300 SSF53300, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 2 hits
PS50234 VWFA, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q70UZ7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MPPLLLLPAI YMLLFFRVSP TISLQEVHVN RETMGKIAVA SKLMWCSAAV
60 70 80 90 100
DILFLLDGSH SIGKGSFERS KRFAIAACDA LDISPGRVRV GALQFGSTPH
110 120 130 140 150
LEFPLDSFST RQEVKESIKG IVFKGGRTET GLALKRLSRG FPGGRNGSVP
160 170 180 190 200
QILIIVTDGK SQGPVALPAK QLRERGIVVF AVGVRFPRWD ELLTLASEPK
210 220 230 240 250
DRHVLLAEQV EDATNGLLST LSSSALCTTA DPDCRVEPHP CERRTLETVR
260 270 280 290 300
ELAGNALCWR GSRQADTVLA LPCPFYSWKR VFQTHPANCY RTICPGPCDS
310 320 330 340 350
QPCQNGGTCI PEGVDRYHCL CPLAFGGEVN CAPKLSLECR IDVLFLLDSS
360 370 380 390 400
AGTTLGGFRR AKAFVKRFVQ AVLREDSRAR VGIASYGRNL MVAVPVGEYQ
410 420 430 440 450
HVPDLIRSLD SIPFSGGPTL TGSALLQVAE HGFGSASRTG QDRPRRVVVL
460 470 480 490 500
LTESRSQDEV SGPAAHARAR ELLLLGVGSE ILQAELVKIT GSPKHVMVHT
510 520 530 540 550
DPQDLFSQIP ELQRRLCSQP RPGCQAQSLD LVFLLDASAS VGRENFAQMQ
560 570 580 590 600
SFIRKCTLRF DVNPDVTQVG LVVYGSRVQT AFGLDTHPTR AAVLRAMSQA
610 620 630 640 650
PYLGGVGSAG TALLHIEDKV MTVQRGARPG VPKAVVMLTG GSGAEDAAVP
660 670 680 690 700
AQKLRGNGIS VLVMSVGAVL REAVRRLAGP RDSLIHVAAY TDLPYHQDML
710 720 730 740 750
IEWLCREARL PVNLCKPSPC MNEGTCVLKN GSYRCECRGG WEGPHCENRI
760 770 780 790
LRGDAPMARS FHQEPAGLQG PTPSQQAPKH LRIGKALSSA K
Length:791
Mass (Da):85,639
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i863CEDEA32983790
GO
Isoform 2 (identifier: Q70UZ7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-218: Missing.
     219-268: STLSSSALCT...WRGSRQADTV → MCCWLSKWRM...GGRWRPSGSS

Note: No experimental confirmation available.
Show »
Length:573
Mass (Da):61,773
Checksum:i3753A8EA6E27B62B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti18V → A in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti156V → I in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti202R → Q in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti225A → E in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti356G → E in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti482L → V in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti487V → G in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti511E → K in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti713N → D in BAE26210 (PubMed:16141072).Curated1
Sequence conflicti730N → I in AAI16637 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0287401 – 218Missing in isoform 2. 1 PublicationAdd BLAST218
Alternative sequenceiVSP_028741219 – 268STLSS…QADTV → MCCWLSKWRMPPMASSAPSA APHSAPLLIQTAGWNLIPVS GGRWRPSGSS in isoform 2. 1 PublicationAdd BLAST50

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ536329 mRNA Translation: CAD60277.1
AK133486 mRNA Translation: BAE21683.1
AK145058 mRNA Translation: BAE26210.1
BC115868 mRNA Translation: AAI15869.1
BC116636 mRNA Translation: AAI16637.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS29923.1 [Q70UZ7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_766428.2, NM_172840.2 [Q70UZ7-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000026068; ENSMUSP00000026068; ENSMUSG00000025082 [Q70UZ7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
240675

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:240675

UCSC genome browser

More...
UCSCi
uc008hzl.1 mouse [Q70UZ7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ536329 mRNA Translation: CAD60277.1
AK133486 mRNA Translation: BAE21683.1
AK145058 mRNA Translation: BAE26210.1
BC115868 mRNA Translation: AAI15869.1
BC116636 mRNA Translation: AAI16637.1
CCDSiCCDS29923.1 [Q70UZ7-1]
RefSeqiNP_766428.2, NM_172840.2 [Q70UZ7-1]

3D structure databases

SMRiQ70UZ7
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026068

PTM databases

PhosphoSitePlusiQ70UZ7

Proteomic databases

PaxDbiQ70UZ7
PRIDEiQ70UZ7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026068; ENSMUSP00000026068; ENSMUSG00000025082 [Q70UZ7-1]
GeneIDi240675
KEGGimmu:240675
UCSCiuc008hzl.1 mouse [Q70UZ7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
340706
MGIiMGI:2684334 Vwa2

Phylogenomic databases

eggNOGiKOG3544 Eukaryota
ENOG410XNMM LUCA
GeneTreeiENSGT00940000159040
HOGENOMiHOG000154835
InParanoidiQ70UZ7
OMAiAASKMMW
OrthoDBi350336at2759
PhylomeDBiQ70UZ7
TreeFamiTF318242

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q70UZ7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000025082 Expressed in 73 organ(s), highest expression level in ear vesicle
GenevisibleiQ70UZ7 MM

Family and domain databases

Gene3Di3.40.50.410, 3 hits
InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR030755 VWA2
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PANTHERiPTHR24020:SF37 PTHR24020:SF37, 1 hit
PfamiView protein in Pfam
PF00008 EGF, 2 hits
PF00092 VWA, 3 hits
SMARTiView protein in SMART
SM00181 EGF, 2 hits
SM00179 EGF_CA, 2 hits
SM00327 VWA, 3 hits
SUPFAMiSSF53300 SSF53300, 3 hits
PROSITEiView protein in PROSITE
PS00022 EGF_1, 1 hit
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 2 hits
PS50234 VWFA, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiVWA2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70UZ7
Secondary accession number(s): Q14AY2, Q14BI0, Q3UM88
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: July 5, 2004
Last modified: May 8, 2019
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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