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Entry version 74 (23 Feb 2022)
Sequence version 1 (05 Jul 2004)
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Protein

Linear gramicidin synthase subunit A

Gene

lgrA

Organism
Brevibacillus parabrevis
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.

Miscellaneous

Linear gramicidin is a pentadecapeptide antibiotic produced during sporulation.

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateCuratedNote: Binds 2 phosphopantetheines covalently.Curated

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.84 mM for valine
  2. KM=2.40 mM for isoleucine

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase, Multifunctional enzyme
Biological processAntibiotic biosynthesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Linear gramicidin synthase subunit A
Including the following 2 domains:
ATP-dependent valine/leucine adenylase
Short name:
Val/LeuA
Alternative name(s):
Valine/leucine activase
ATP-dependent glycine adenylase
Short name:
GlyA
Alternative name(s):
Glycine activase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:lgrA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBrevibacillus parabrevis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri54914 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001930891 – 2273Linear gramicidin synthase subunit AAdd BLAST2273

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei728O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei1759O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Large multienzyme complex composed of 4 subunits; LgrA, LgrB, LgrC and LgrD.

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
54914.AV540_01965

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12273
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q70LM7

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini693 – 767Carrier 1PROSITE-ProRule annotationAdd BLAST75
Domaini1724 – 1798Carrier 2PROSITE-ProRule annotationAdd BLAST75

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 144GARTAdd BLAST144

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Two module-bearing peptide synthase with a C-terminal epimerization domain, which is probably inactive. Each module incorporates one amino acid into the peptide product and can be further subdivided into domains responsible for substrate adenylation, thiolation, condensation (not for the initiation module), and epimerization (optional). At the N-terminus, contains a N-formyltransferase domain that is probably responsible for the formylation of the first incorporated amino acid.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1200.10, 2 hits
3.30.300.30, 2 hits
3.30.559.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR002376, Formyl_transf_N
IPR036477, Formyl_transf_N_sf
IPR010060, NRPS_synth
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00501, AMP-binding, 2 hits
PF13193, AMP-binding_C, 2 hits
PF00668, Condensation, 2 hits
PF00551, Formyl_trans_N, 1 hit
PF00550, PP-binding, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00823, PKS_PP, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47336, SSF47336, 2 hits
SSF53328, SSF53328, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01733, AA-adenyl-dom, 2 hits
TIGR01720, NRPS-para261, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00455, AMP_BINDING, 2 hits
PS50075, CARRIER, 2 hits
PS00012, PHOSPHOPANTETHEINE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q70LM7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRILFLTTFM SKGNKVVRYL ESLHHEVVIC QEKVHAQSAN LQEIDWIVSY
60 70 80 90 100
AYGYILDKEI VSRFRGRIIN LHPSLLPWNK GRDPVFWSVW DETPKGVTIH
110 120 130 140 150
LIDEHVDTGD ILVQEEIAFA DEDTLLDCYN KANQAIEELF IREWENIVHG
160 170 180 190 200
RIAPYRQTAG GTLHFKADRD FYKNLNMTTV RELLALKRLC AEPKRGEKPI
210 220 230 240 250
DKTFHQLFEQ QVEMTPDHVA VVDRGQSLTY KQLNERANQL AHHLRGKGVK
260 270 280 290 300
PDDQVAIMLD KSLDMIVSIL AVMKAGGAYV PIDPDYPGER IAYMLADSSA
310 320 330 340 350
AILLTNALHE EKANGACDII DVHDPDSYSE NTNNLPHVNR PDDLVYVMYT
360 370 380 390 400
SGSTGLAKGV MIEHHNLVNF CEWYRPYFGV TPADKALVYS SFSFDGSALD
410 420 430 440 450
IFTHLLAGAA LHIVPSERKY DLDALNDYCN QEGITISYLP TGAAEQFMQM
460 470 480 490 500
DNQSFRVVIT GGDVLKKIER NGTYKLYNGY GPTECTIMVT MFEVDKPYAN
510 520 530 540 550
IPIGKPIDRT RILILDEALA LQPIGVAGEL FIVGEGLGRG YLNRPELTAE
560 570 580 590 600
KFIVHPQTGE RMYRTGDRAR FLPDGNIEFL GRLDNLVKIR GYRIEPGEIE
610 620 630 640 650
PFLMNHPLIE LTTVLAKEQA DGRKYLVGYY VAPEEIPHGE LREWLGNDLP
660 670 680 690 700
DYMIPTYFVH MKAFPLTANG KVDRRALPDV QADAELLGED YVAPTDELEQ
710 720 730 740 750
QLAQVWSHVL GIPQMGIDDH FLERGGDSIK VMQLIHQLKN IGLSLRYDQL
760 770 780 790 800
FTHPTIRQLK RLLTEQKQVS LEPLRELDEQ AEYETSAVEK RMYIIQQQDV
810 820 830 840 850
ESIAYNVVYT INFPLTVDTE QIRVALEQLV LRHEGLRSTY HMRGDEIVKR
860 870 880 890 900
IVPRAELSFV RQTGEEESVQ SLLAEQIKPF DLAKAPLLRA GVIETADKKV
910 920 930 940 950
LWFDSHHILL DGLSKSILAR ELQALLGQQV LSPVEKTYKS FARWQNEWFA
960 970 980 990 1000
SDEYEQQIAY WKTLLQGELP AVQLPTKKRP PQLTFDGAIQ MYRVNPEITR
1010 1020 1030 1040 1050
KLKATAAKHD LTLYMLMLTI VSIWLSKMNS DSNQVILGTV TDGRQHPDTR
1060 1070 1080 1090 1100
ELLGMFVNTL PLLLSIDHEE SFLHNLQQVK AKLLPALQNQ YVPFDKILEA
1110 1120 1130 1140 1150
ARVKREGNRH PLFDVMFMMQ GAPETELESN MHHINAGISK FDLTLEVLER
1160 1170 1180 1190 1200
ENGLNIVFEY NTHLFDEGMI LRMVAQFEHL LLQAVHGLDQ QVKRFELVTE
1210 1220 1230 1240 1250
DEKRDLFLRV NDTAKAYPNK LIMSMLEDWA AATPDKTALV FREQRVTYRE
1260 1270 1280 1290 1300
LNERVNQLAH TLREKGVQPD DLVMLMAERS VEMMVAIFAV LKAGGAYLPI
1310 1320 1330 1340 1350
DPHSPAERIA YIFADSGAKL VLAQSPFVEK ASMAEVVLDL NSASSYAADT
1360 1370 1380 1390 1400
SNPPLVNQPG DLVYVMYTSG STGKPKGVMI EHGALLNVLH GMQDEYPLLQ
1410 1420 1430 1440 1450
DDAFLLKTTY IFDISVAEIF GWVPGRGKLV ILEPEAEKNP KAIWQAVVGA
1460 1470 1480 1490 1500
GITHINFVPS MLIPFVEYLE GRTEANRLRY ILACGEAMPD ELVPKVYEVL
1510 1520 1530 1540 1550
PEVKLENIYG PTEATIYASR YSLAKGSQES PVPIGKPLPN YRMYIINRHG
1560 1570 1580 1590 1600
QLQPIGVPGE LCIAGASLAR GYLNNPALTE EKFTPHPLEK GERIYRTGDL
1610 1620 1630 1640 1650
ARYREDGNIE YLGRMDHQVK IRGYRIELDE IRSKLIQEET IQDAVVVARN
1660 1670 1680 1690 1700
DQNGQAYLCA YLLSEQEWTV GQLRELLRRE LPEYMIPAHF VLLKQFPLTA
1710 1720 1730 1740 1750
NGKLDRKALP EPDGSVKAEA EYAAPRTELE ATLAHIWGEV LGIERIGIRD
1760 1770 1780 1790 1800
NFFELGGDSI KGLQIASRLQ RINWTMVINH LFLYPTIEQI APFVTSEQVV
1810 1820 1830 1840 1850
IEQGLVEGLV KLTPIQRDFF ERITADRHHW NQARMLFCRD GLEREWVVET
1860 1870 1880 1890 1900
LNALVLQHDA LRMRFRETEQ GIVQFHQGNE GKLFGFHVFD CTEELDIAKK
1910 1920 1930 1940 1950
VEEQANVLQS GMNLQEGPLV QAALFMTRTG DHLLLAIHQL VVDEASWRII
1960 1970 1980 1990 2000
LEDFQTAYKQ KAAGEPIALP NKTHSYQSWA EELHNAANSK KLTSELGYWR
2010 2020 2030 2040 2050
KIASSPTRPL PQDQEPLSRT EQSTATAAIR FAKAETANLL HEANHAYQTE
2060 2070 2080 2090 2100
AQELLLAALG MALRDWTRAD DVTVFLEKDG RESAAKGLDV SRTVGWFHSL
2110 2120 2130 2140 2150
FPVVLSAARS GDPGEQIKQV KEMLRAIPHQ GSGYSILKQL TDLRHKHPDD
2160 2170 2180 2190 2200
FTLQPKIVVH AWEQLDAGLE TDWLTLSHLP QGSVRGANAE RMQQLDVFSK
2210 2220 2230 2240 2250
ISNGELTIHI QYHRDEYRKA TIDKLLELYQ AHLNALLAHC LQKTETELTP
2260 2270
SDFVDKNLSR SELDDIMDLI SDL
Length:2,273
Mass (Da):257,859
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2CAF8DF6CCE302C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ566197 Genomic DNA Translation: CAD92849.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ566197 Genomic DNA Translation: CAD92849.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5ES5X-ray2.80A/B2-766[»]
5ES6X-ray2.46A2-684[»]
5ES7X-ray2.81A2-684[»]
5ES8X-ray2.55A/B2-766[»]
5ES9X-ray3.77A/B2-766[»]
5JNFX-ray2.75A/B/C/D2-584[»]
6MFWX-ray2.50A2-1198[»]
6MFXX-ray2.20A2-1198[»]
6MFYX-ray2.50A2-1716[»]
6MFZX-ray6.00A/B2-1802[»]
6MG0X-ray6.00A/B2-1716[»]
6ULZX-ray3.10A2-684[»]
SMRiQ70LM7
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

STRINGi54914.AV540_01965

Family and domain databases

Gene3Di1.10.1200.10, 2 hits
3.30.300.30, 2 hits
3.30.559.10, 2 hits
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR002376, Formyl_transf_N
IPR036477, Formyl_transf_N_sf
IPR010060, NRPS_synth
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
PfamiView protein in Pfam
PF00501, AMP-binding, 2 hits
PF13193, AMP-binding_C, 2 hits
PF00668, Condensation, 2 hits
PF00551, Formyl_trans_N, 1 hit
PF00550, PP-binding, 2 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 2 hits
SUPFAMiSSF47336, SSF47336, 2 hits
SSF53328, SSF53328, 1 hit
TIGRFAMsiTIGR01733, AA-adenyl-dom, 2 hits
TIGR01720, NRPS-para261, 1 hit
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 2 hits
PS50075, CARRIER, 2 hits
PS00012, PHOSPHOPANTETHEINE, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLGRA_BREPA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70LM7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
Last sequence update: July 5, 2004
Last modified: February 23, 2022
This is version 74 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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