Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 70 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Linear gramicidin synthase subunit A

Gene

lgrA

Organism
Brevibacillus parabrevis
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide.

Miscellaneous

Linear gramicidin is a pentadecapeptide antibiotic produced during sporulation.

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateCuratedNote: Binds 2 phosphopantetheines covalently.Curated

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.84 mM for valine
  2. KM=2.40 mM for isoleucine

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionLigase, Multifunctional enzyme
    Biological processAntibiotic biosynthesis

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Linear gramicidin synthase subunit A
    Including the following 2 domains:
    ATP-dependent valine/leucine adenylase
    Short name:
    Val/LeuA
    Alternative name(s):
    Valine/leucine activase
    ATP-dependent glycine adenylase
    Short name:
    GlyA
    Alternative name(s):
    Glycine activase
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:lgrA
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBrevibacillus parabrevis
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri54914 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeBrevibacillus

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001930891 – 2273Linear gramicidin synthase subunit AAdd BLAST2273

    Amino acid modifications

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei728O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
    Modified residuei1759O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

    Keywords - PTMi

    Phosphopantetheine, Phosphoprotein

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    <p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

    Large multienzyme complex composed of 4 subunits; LgrA, LgrB, LgrC and LgrD.

    <p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

    Secondary structure

    12273
    Legend: HelixTurnBeta strandPDB Structure known for this area
    Show more details

    3D structure databases

    SWISS-MODEL Repository - a database of annotated 3D protein structure models

    More...
    SMRi
    Q70LM7

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    Protein Data Bank in Europe - Knowledge Base

    More...
    PDBe-KBi
    Search...

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini693 – 767Carrier 1PROSITE-ProRule annotationAdd BLAST75
    Domaini1724 – 1798Carrier 2PROSITE-ProRule annotationAdd BLAST75

    Region

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 144GARTAdd BLAST144

    <p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

    Two module-bearing peptide synthase with a C-terminal epimerization domain, which is probably inactive. Each module incorporates one amino acid into the peptide product and can be further subdivided into domains responsible for substrate adenylation, thiolation, condensation (not for the initiation module), and epimerization (optional). At the N-terminus, contains a N-formyltransferase domain that is probably responsible for the formylation of the first incorporated amino acid.

    <p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Repeat

    Family and domain databases

    Gene3D Structural and Functional Annotation of Protein Families

    More...
    Gene3Di
    1.10.1200.10, 2 hits
    3.30.559.10, 2 hits
    3.40.50.12780, 2 hits

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR010071, AA_adenyl_domain
    IPR036736, ACP-like_sf
    IPR025110, AMP-bd_C
    IPR020845, AMP-binding_CS
    IPR000873, AMP-dep_Synth/Lig
    IPR042099, AMP-dep_Synthh-like_sf
    IPR023213, CAT-like_dom_sf
    IPR001242, Condensatn
    IPR002376, Formyl_transf_N
    IPR036477, Formyl_transf_N_sf
    IPR010060, NRPS_synth
    IPR020806, PKS_PP-bd
    IPR009081, PP-bd_ACP
    IPR006162, Ppantetheine_attach_site

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF00501, AMP-binding, 2 hits
    PF13193, AMP-binding_C, 2 hits
    PF00668, Condensation, 2 hits
    PF00551, Formyl_trans_N, 1 hit
    PF00550, PP-binding, 2 hits

    Simple Modular Architecture Research Tool; a protein domain database

    More...
    SMARTi
    View protein in SMART
    SM00823, PKS_PP, 2 hits

    Superfamily database of structural and functional annotation

    More...
    SUPFAMi
    SSF47336, SSF47336, 2 hits
    SSF53328, SSF53328, 1 hit

    TIGRFAMs; a protein family database

    More...
    TIGRFAMsi
    TIGR01733, AA-adenyl-dom, 2 hits
    TIGR01720, NRPS-para261, 1 hit

    PROSITE; a protein domain and family database

    More...
    PROSITEi
    View protein in PROSITE
    PS00455, AMP_BINDING, 2 hits
    PS50075, CARRIER, 2 hits
    PS00012, PHOSPHOPANTETHEINE, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    Q70LM7-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MRILFLTTFM SKGNKVVRYL ESLHHEVVIC QEKVHAQSAN LQEIDWIVSY
    60 70 80 90 100
    AYGYILDKEI VSRFRGRIIN LHPSLLPWNK GRDPVFWSVW DETPKGVTIH
    110 120 130 140 150
    LIDEHVDTGD ILVQEEIAFA DEDTLLDCYN KANQAIEELF IREWENIVHG
    160 170 180 190 200
    RIAPYRQTAG GTLHFKADRD FYKNLNMTTV RELLALKRLC AEPKRGEKPI
    210 220 230 240 250
    DKTFHQLFEQ QVEMTPDHVA VVDRGQSLTY KQLNERANQL AHHLRGKGVK
    260 270 280 290 300
    PDDQVAIMLD KSLDMIVSIL AVMKAGGAYV PIDPDYPGER IAYMLADSSA
    310 320 330 340 350
    AILLTNALHE EKANGACDII DVHDPDSYSE NTNNLPHVNR PDDLVYVMYT
    360 370 380 390 400
    SGSTGLAKGV MIEHHNLVNF CEWYRPYFGV TPADKALVYS SFSFDGSALD
    410 420 430 440 450
    IFTHLLAGAA LHIVPSERKY DLDALNDYCN QEGITISYLP TGAAEQFMQM
    460 470 480 490 500
    DNQSFRVVIT GGDVLKKIER NGTYKLYNGY GPTECTIMVT MFEVDKPYAN
    510 520 530 540 550
    IPIGKPIDRT RILILDEALA LQPIGVAGEL FIVGEGLGRG YLNRPELTAE
    560 570 580 590 600
    KFIVHPQTGE RMYRTGDRAR FLPDGNIEFL GRLDNLVKIR GYRIEPGEIE
    610 620 630 640 650
    PFLMNHPLIE LTTVLAKEQA DGRKYLVGYY VAPEEIPHGE LREWLGNDLP
    660 670 680 690 700
    DYMIPTYFVH MKAFPLTANG KVDRRALPDV QADAELLGED YVAPTDELEQ
    710 720 730 740 750
    QLAQVWSHVL GIPQMGIDDH FLERGGDSIK VMQLIHQLKN IGLSLRYDQL
    760 770 780 790 800
    FTHPTIRQLK RLLTEQKQVS LEPLRELDEQ AEYETSAVEK RMYIIQQQDV
    810 820 830 840 850
    ESIAYNVVYT INFPLTVDTE QIRVALEQLV LRHEGLRSTY HMRGDEIVKR
    860 870 880 890 900
    IVPRAELSFV RQTGEEESVQ SLLAEQIKPF DLAKAPLLRA GVIETADKKV
    910 920 930 940 950
    LWFDSHHILL DGLSKSILAR ELQALLGQQV LSPVEKTYKS FARWQNEWFA
    960 970 980 990 1000
    SDEYEQQIAY WKTLLQGELP AVQLPTKKRP PQLTFDGAIQ MYRVNPEITR
    1010 1020 1030 1040 1050
    KLKATAAKHD LTLYMLMLTI VSIWLSKMNS DSNQVILGTV TDGRQHPDTR
    1060 1070 1080 1090 1100
    ELLGMFVNTL PLLLSIDHEE SFLHNLQQVK AKLLPALQNQ YVPFDKILEA
    1110 1120 1130 1140 1150
    ARVKREGNRH PLFDVMFMMQ GAPETELESN MHHINAGISK FDLTLEVLER
    1160 1170 1180 1190 1200
    ENGLNIVFEY NTHLFDEGMI LRMVAQFEHL LLQAVHGLDQ QVKRFELVTE
    1210 1220 1230 1240 1250
    DEKRDLFLRV NDTAKAYPNK LIMSMLEDWA AATPDKTALV FREQRVTYRE
    1260 1270 1280 1290 1300
    LNERVNQLAH TLREKGVQPD DLVMLMAERS VEMMVAIFAV LKAGGAYLPI
    1310 1320 1330 1340 1350
    DPHSPAERIA YIFADSGAKL VLAQSPFVEK ASMAEVVLDL NSASSYAADT
    1360 1370 1380 1390 1400
    SNPPLVNQPG DLVYVMYTSG STGKPKGVMI EHGALLNVLH GMQDEYPLLQ
    1410 1420 1430 1440 1450
    DDAFLLKTTY IFDISVAEIF GWVPGRGKLV ILEPEAEKNP KAIWQAVVGA
    1460 1470 1480 1490 1500
    GITHINFVPS MLIPFVEYLE GRTEANRLRY ILACGEAMPD ELVPKVYEVL
    1510 1520 1530 1540 1550
    PEVKLENIYG PTEATIYASR YSLAKGSQES PVPIGKPLPN YRMYIINRHG
    1560 1570 1580 1590 1600
    QLQPIGVPGE LCIAGASLAR GYLNNPALTE EKFTPHPLEK GERIYRTGDL
    1610 1620 1630 1640 1650
    ARYREDGNIE YLGRMDHQVK IRGYRIELDE IRSKLIQEET IQDAVVVARN
    1660 1670 1680 1690 1700
    DQNGQAYLCA YLLSEQEWTV GQLRELLRRE LPEYMIPAHF VLLKQFPLTA
    1710 1720 1730 1740 1750
    NGKLDRKALP EPDGSVKAEA EYAAPRTELE ATLAHIWGEV LGIERIGIRD
    1760 1770 1780 1790 1800
    NFFELGGDSI KGLQIASRLQ RINWTMVINH LFLYPTIEQI APFVTSEQVV
    1810 1820 1830 1840 1850
    IEQGLVEGLV KLTPIQRDFF ERITADRHHW NQARMLFCRD GLEREWVVET
    1860 1870 1880 1890 1900
    LNALVLQHDA LRMRFRETEQ GIVQFHQGNE GKLFGFHVFD CTEELDIAKK
    1910 1920 1930 1940 1950
    VEEQANVLQS GMNLQEGPLV QAALFMTRTG DHLLLAIHQL VVDEASWRII
    1960 1970 1980 1990 2000
    LEDFQTAYKQ KAAGEPIALP NKTHSYQSWA EELHNAANSK KLTSELGYWR
    2010 2020 2030 2040 2050
    KIASSPTRPL PQDQEPLSRT EQSTATAAIR FAKAETANLL HEANHAYQTE
    2060 2070 2080 2090 2100
    AQELLLAALG MALRDWTRAD DVTVFLEKDG RESAAKGLDV SRTVGWFHSL
    2110 2120 2130 2140 2150
    FPVVLSAARS GDPGEQIKQV KEMLRAIPHQ GSGYSILKQL TDLRHKHPDD
    2160 2170 2180 2190 2200
    FTLQPKIVVH AWEQLDAGLE TDWLTLSHLP QGSVRGANAE RMQQLDVFSK
    2210 2220 2230 2240 2250
    ISNGELTIHI QYHRDEYRKA TIDKLLELYQ AHLNALLAHC LQKTETELTP
    2260 2270
    SDFVDKNLSR SELDDIMDLI SDL
    Length:2,273
    Mass (Da):257,859
    Last modified:July 5, 2004 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA2CAF8DF6CCE302C
    GO

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AJ566197 Genomic DNA Translation: CAD92849.1

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AJ566197 Genomic DNA Translation: CAD92849.1

    3D structure databases

    Select the link destinations:

    Protein Data Bank Europe

    More...
    PDBei

    Protein Data Bank RCSB

    More...
    RCSB PDBi

    Protein Data Bank Japan

    More...
    PDBji
    Links Updated
    PDB entryMethodResolution (Å)ChainPositionsPDBsum
    5ES5X-ray2.80A/B2-766[»]
    5ES6X-ray2.46A2-684[»]
    5ES7X-ray2.81A2-684[»]
    5ES8X-ray2.55A/B2-766[»]
    5ES9X-ray3.77A/B2-766[»]
    5JNFX-ray2.75A/B/C/D2-584[»]
    6MFWX-ray2.50A2-1198[»]
    6MFXX-ray2.20A2-1198[»]
    6MFYX-ray2.50A2-1716[»]
    6MFZX-ray6.00A/B2-1802[»]
    6MG0X-ray6.00A/B2-1716[»]
    6ULZX-ray3.10A2-684[»]
    SMRiQ70LM7
    ModBaseiSearch...
    PDBe-KBiSearch...

    Family and domain databases

    Gene3Di1.10.1200.10, 2 hits
    3.30.559.10, 2 hits
    3.40.50.12780, 2 hits
    InterProiView protein in InterPro
    IPR010071, AA_adenyl_domain
    IPR036736, ACP-like_sf
    IPR025110, AMP-bd_C
    IPR020845, AMP-binding_CS
    IPR000873, AMP-dep_Synth/Lig
    IPR042099, AMP-dep_Synthh-like_sf
    IPR023213, CAT-like_dom_sf
    IPR001242, Condensatn
    IPR002376, Formyl_transf_N
    IPR036477, Formyl_transf_N_sf
    IPR010060, NRPS_synth
    IPR020806, PKS_PP-bd
    IPR009081, PP-bd_ACP
    IPR006162, Ppantetheine_attach_site
    PfamiView protein in Pfam
    PF00501, AMP-binding, 2 hits
    PF13193, AMP-binding_C, 2 hits
    PF00668, Condensation, 2 hits
    PF00551, Formyl_trans_N, 1 hit
    PF00550, PP-binding, 2 hits
    SMARTiView protein in SMART
    SM00823, PKS_PP, 2 hits
    SUPFAMiSSF47336, SSF47336, 2 hits
    SSF53328, SSF53328, 1 hit
    TIGRFAMsiTIGR01733, AA-adenyl-dom, 2 hits
    TIGR01720, NRPS-para261, 1 hit
    PROSITEiView protein in PROSITE
    PS00455, AMP_BINDING, 2 hits
    PS50075, CARRIER, 2 hits
    PS00012, PHOSPHOPANTETHEINE, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLGRA_BREPA
    <p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70LM7
    <p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 6, 2005
    Last sequence update: July 5, 2004
    Last modified: October 7, 2020
    This is version 70 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    <p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. SIMILARITY comments
      Index of protein domains and families
    UniProt is an ELIXIR core data resource
    Main funding by: National Institutes of Health

    We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

    Do not show this banner again