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Entry version 80 (31 Jul 2019)
Sequence version 1 (05 Jul 2004)
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Protein
Submitted name:

Putative alpha-amylase

Gene

amyA

Organism
Butyrivibrio fibrisolvens
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidaseImported, Hydrolase

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
CBM26 Carbohydrate-Binding Module Family 26
GH13 Glycoside Hydrolase Family 13

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative alpha-amylaseImported (EC:3.2.1.1Imported)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:amyAImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiButyrivibrio fibrisolvensImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri831 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeButyrivibrio

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1307 – 1329HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 33Sequence analysisAdd BLAST33
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500428420734 – 1333Sequence analysisAdd BLAST1300

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 425AamyInterPro annotationAdd BLAST372
Domaini435 – 512Aamy_CInterPro annotationAdd BLAST78

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni927 – 963DisorderedSequence analysisAdd BLAST37
Regioni1031 – 1085DisorderedSequence analysisAdd BLAST55
Regioni1149 – 1198DisorderedSequence analysisAdd BLAST50
Regioni1234 – 1287DisorderedSequence analysisAdd BLAST54

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1041 – 1067PolyampholyteSequence analysisAdd BLAST27
Compositional biasi1068 – 1085AcidicSequence analysisAdd BLAST18
Compositional biasi1174 – 1198PolarSequence analysisAdd BLAST25
Compositional biasi1234 – 1251PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1252 – 1281AcidicSequence analysisAdd BLAST30

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105E54 Bacteria
COG0366 LUCA

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 3 hits
2.60.40.1180, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031319 A-amylase_C
IPR006046 Alpha_amylase
IPR031965 CBM26
IPR006047 Glyco_hydro_13_cat_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF16738 CBM26, 3 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00110 ALPHAAMYLASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00642 Aamy, 1 hit
SM00632 Aamy_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51445 SSF51445, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q70JA8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKMGKMAKR FVAVAMSLAM VAGIPGANLK AFATPGIDSV QAASAVSRSS
60 70 80 90 100
IHDGSILHAF CWNFNTIKEK MPEIAAAGYT AVQTSPINEC LSIHNGMALY
110 120 130 140 150
GDTEDEGRWY YHYQPTDWKI GNYQLGSRDE FKAMCDEADK YGIGVIVDID
160 170 180 190 200
PNHTTPVFDQ VSDDLKAAAG GEDSLYHIGA KDGGMAYDNR ISVTYDAMGG
210 220 230 240 250
LPDVDTENPG FQNYFYEFLQ DCIACGADGF RIDTAKHIAL PDDGVAEEYA
260 270 280 290 300
GQEGRNNFYP NMKASINEKA AKSYDDLFVY GEVLDGDAAR LAAYQDMLGG
310 320 330 340 350
TCASNYGGAI RNAASSGNVS VKKLLNYKIS DDTSTGTTYT ADSNKLVTWV
360 370 380 390 400
ESHDNYINDK SYNEVDDREV ILGWAIITAR ADGTPLFFSR PEGSSAENPW
410 420 430 440 450
GANRIGDAGS DIYKAPEVVA VNKFRTAMEG LSENLRNPGN NSSILMIERG
460 470 480 490 500
NKGVVIVNAS ENDFALDSET NLSDGTYVDS VEGRTGLYTV SDGNIYGTVP
510 520 530 540 550
AKSVVVLDTL ADGDYSTIFF HNTDGWNSVS AIACDNTFAC DYTQDNWWKV
560 570 580 590 600
TIPAKEFKVT FTDGEKQSAE FSIGADTGRF MTAKSDKIYG SKAEAEEALG
610 620 630 640 650
IVTKTVYFLN SEEWKSVYAY AWTDATQHLG GWPGAPIVNE EGYWWKADVK
660 670 680 690 700
MIGDQNFSII FNNNEGSQTV DIPMDDMSKN VITISAEQPG GNLVVDRYSS
710 720 730 740 750
KAEAEEATGI NGTSTTVHFY DAAGWGKVGV YTWGDVDLGG WPGAECEYEG
760 770 780 790 800
DGWWKKTINC GPSSNFNIIF NNMPTGDDDK RQTDDMKCDS LKKVYFIGAN
810 820 830 840 850
YKYGSKAAAL DALANDNLKL EKNLHPELNP VEEPTDRPVE EEPVLGEDEV
860 870 880 890 900
KIYYYNTANW DNVNMYAWTD GANTEYFGGW PGKAMQHIGG NWYSVSVNKA
910 920 930 940 950
ALTHEGLHLI ANNGDGEQIN DVALISERPN IEEKPSEPDK PAPSEPEEPT
960 970 980 990 1000
EPEKKLKPIQ EEEADKEGYT KIYIQLDVDK FPEAANLYAW AEGVGDIDGI
1010 1020 1030 1040 1050
GGWPGLSMTH IGNGWHSINF PDKYLNKAEE VSEEASEEKV EDEKSEVVTD
1060 1070 1080 1090 1100
DTTKEVVENN EVEETEKASD EVISEEESQE PEEDSLVEEV REILTSLVNL
1110 1120 1130 1140 1150
ITSAFNPLEV KAAEHQTFAD GIHLIVNNGN GYQEDDVNAR FTTVRPSAEE
1160 1170 1180 1190 1200
LKQEEELVVE PTPAPAPAPQ PGGASGNGGS SSGSSSSSGS SASSGSASAT
1210 1220 1230 1240 1250
PAQQIASIAE SQVPLGVSPV KVVEDSSVVK KVASKVRKST SKSKEVSAEE
1260 1270 1280 1290 1300
EAVDTTSEVE TEESVELPDA EIPEVDEAET TEPEKEEVRI VDEGVPEAAV
1310 1320 1330
DTGSSNLAVI ILIIVAAVVI IGGAGFVVVR KRK
Length:1,333
Mass (Da):144,616
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA1FF96014748D329
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ578026 Genomic DNA Translation: CAE17325.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ578026 Genomic DNA Translation: CAE17325.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

CAZyiCBM26 Carbohydrate-Binding Module Family 26
GH13 Glycoside Hydrolase Family 13

Phylogenomic databases

eggNOGiENOG4105E54 Bacteria
COG0366 LUCA

Family and domain databases

Gene3Di2.60.40.10, 3 hits
2.60.40.1180, 1 hit
InterProiView protein in InterPro
IPR031319 A-amylase_C
IPR006046 Alpha_amylase
IPR031965 CBM26
IPR006047 Glyco_hydro_13_cat_dom
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF16738 CBM26, 3 hits
PRINTSiPR00110 ALPHAAMYLASE
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SM00632 Aamy_C, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ70JA8_BUTFI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70JA8
Secondary accession number(s): D4J1R3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: July 31, 2019
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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