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Entry version 129 (02 Dec 2020)
Sequence version 2 (31 Oct 2006)
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Protein

Aldehyde dehydrogenase family 3 member H1

Gene

ALDH3H1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long-chain saturated aldehydes are preferred substrates, while the short-chain aldehyde propanal is a weak substrate. Is strictely NAD+ specific.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Thiol-based regulation. Inactivation after dimerization under oxidizing conditions.1 Publication

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=510 µM for propionaldehyde1 Publication
  2. KM=71 µM for hexanal1 Publication
  3. KM=29 µM for octanal1 Publication
  4. KM=8 µM for nonanal1 Publication
  5. KM=5 µM for dodecanal1 Publication
  6. KM=180 µM for trans-2-hexenal1 Publication
  7. KM=3 µM for trans-2-nonenal1 Publication
  8. KM=40.3 µM for 4-hydroxynonenal1 Publication
  9. KM=421 µM for NAD+ (in the presence of hexanal as co-substrate)1 Publication
  10. KM=119 µM for NAD+ (in the presence of trans-2-nonenal as co-substrate)1 Publication
  1. Vmax=7.3 µmol/min/mg enzyme with propionaldehyde as substrate1 Publication
  2. Vmax=12 µmol/min/mg enzyme with hexanal as substrate1 Publication
  3. Vmax=18 µmol/min/mg enzyme with octanal as substrate1 Publication
  4. Vmax=19.2 µmol/min/mg enzyme with nonanal as substrate1 Publication
  5. Vmax=23.9 µmol/min/mg enzyme with dodecanal as substrate1 Publication
  6. Vmax=2.4 µmol/min/mg enzyme with trans-2-hexenal as substrate1 Publication
  7. Vmax=2.9 µmol/min/mg enzyme with trans-2-nonenal as substrate1 Publication
  8. Vmax=1.4 µmol/min/mg enzyme with 4-hydroxynonenal as substrate1 Publication

pH dependencei

Optimum pH is 8.0.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections ('Function', 'PTM / Processing', 'Pathology and Biotech') according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei123Transition state stabilizerBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei218Proton acceptorPROSITE-ProRule annotation1
Active sitei253NucleophilePROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi196 – 201NADBy similarity6

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase
Biological processStress response
LigandNAD

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT1G44170-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Aldehyde dehydrogenase family 3 member H1 (EC:1.2.1.3)
Short name:
AtALDH4
Short name:
Ath-ALDH4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ALDH3H1
Synonyms:ALDH4
Ordered Locus Names:At1g44170
ORF Names:T7O23.15
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G44170

The Arabidopsis Information Resource

More...
TAIRi
locus:2205851, AT1G44170

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Increased sensitivity to salt stress.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi45C → S: Decreased solubility, loss of dimerization and strongly decreased activity. 1 Publication1
Mutagenesisi149E → D: Small effect on NAD(+) interaction, but 40% loss of efficiency. Ability to use NADP(+). 70% loss of efficiency with NAD(+); when associated with V-200. Impaired affinity for both cofactors and decreased catalytic efficiency; when associated with G-200. 1 Publication1
Mutagenesisi149E → N: Ability to use NADP(+) and 33% decreased efficiency with NAD(+). 70% loss of efficiency with NAD(+); when associated with V-200. Impaired affinity for both cofactors and decreased catalytic efficiency; when associated with G-200. 1 Publication1
Mutagenesisi149E → Q: Loss of specificity for NAD(+) and loss of 25% efficiency. 15% efficiency with NAD(+); when associated with V-200. Impaired affinity for both cofactors and decreased catalytic efficiency; when associated with G-200. 1 Publication1
Mutagenesisi149E → T: Loss of specificity and increased NADP(+) binding. Decerased catalytic efficiency. Loss of cofactor specificity and same lower efficiency with both; when associated with V-200. Impaired affinity for both cofactors and decreased catalytic efficiency; when associated with G-200. Changed coenzyme preference from NAD(+) to NADP(+), but no effect on the catalytic efficiency; when associated with R-178 and V-200. 1 Publication1
Mutagenesisi178V → R: Changed coenzyme preference from NAD(+) to NADP(+), but no effect on the catalytic efficiency; when associated with T-149 and V-200. 1 Publication1
Mutagenesisi200I → G: Changed coenzyme preference from NAD(+) to NADP(+), but impaired affinities for both cofactors. No effect on the interaction with the substrate. Impaired affinities for both cofactors and decreased catalytic efficiencies; when associated with D-149, Q-149, N-149 or T-149. 2 Publications1
Mutagenesisi200I → V: Also able to use NADP(+) as coenzyme, but no effect on the interaction with the substrate. 15% efficiency with NAD(+); when associated with Q-149. 70% loss of efficiency with NAD(+); when associated with D-149 or N-149. Loss of cofactor specificity and same lower efficiency with both; when associated with T-149. Changed coenzyme preference from NAD(+) to NADP(+), but no effect on the catalytic efficiency; when associated with T-149 and R-178. 2 Publications1
Mutagenesisi247C → S: No effect on solubility, but 10% loss of activity. 1 Publication1
Mutagenesisi253C → S: No effect on solubility, but loss of activity. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002560601 – 484Aldehyde dehydrogenase family 3 member H1Add BLAST484

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi45Interchain

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q70DU8

PRoteomics IDEntifications database

More...
PRIDEi
Q70DU8

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
244811 [Q70DU8-1]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q70DU8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform alpha is expressed in expanded leaves and flowers. Detected in seedlings. Isoform beta is mainly expressed in flowers. Detected in leaves and seedlings.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By abscisic acid (ABA), dehydration and salt stress in roots. Isoform alpha is up-regulated in leaves but not in roots upon salt treatment. Isoforn beta is up-regulated by salt treatment in both roots and leaves.3 Publications

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q70DU8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q70DU8, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer and homomultimer.

1 Publication

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G44170.2

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q70DU8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2456, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005391_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q70DU8

Identification of Orthologs from Complete Genome Data

More...
OMAi
RHGKRWM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q70DU8

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.309.10, 1 hit
3.40.605.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016161, Ald_DH/histidinol_DH
IPR016163, Ald_DH_C
IPR029510, Ald_DH_CS_GLU
IPR016162, Ald_DH_N
IPR015590, Aldehyde_DH_dom
IPR012394, Aldehyde_DH_NAD(P)

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00171, Aldedh, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036492, ALDH, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53720, SSF53720, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative promoter usage and alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences. An alternative promoter within intron 1 may direct expression of several alternative transcripts, including isoform beta.
Isoform alpha (identifier: Q70DU8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAAKKVFGSA EASNLVTELR RSFDDGVTRG YEWRVTQLKK LMIICDNHEP
60 70 80 90 100
EIVAALRDDL GKPELESSVY EVSLLRNSIK LALKQLKNWM APEKAKTSLT
110 120 130 140 150
TFPASAEIVS EPLGVVLVIS AWNYPFLLSI DPVIGAISAG NAVVLKPSEL
160 170 180 190 200
APASSALLTK LLEQYLDPSA VRVVEGAVTE TSALLEQKWD KIFYTGSSKI
210 220 230 240 250
GRVIMAAAAK HLTPVVLELG GKSPVVVDSD TDLKVTVRRI IVGKWGCNNG
260 270 280 290 300
QACVSPDYIL TTKEYAPKLI DAMKLELEKF YGKNPIESKD MSRIVNSNHF
310 320 330 340 350
DRLSKLLDEK EVSDKIVYGG EKDRENLKIA PTILLDVPLD SLIMSEEIFG
360 370 380 390 400
PLLPILTLNN LEESFDVIRS RPKPLAAYLF THNKKLKERF AATVSAGGIV
410 420 430 440 450
VNDIAVHLAL HTLPFGGVGE SGMGAYHGKF SFDAFSHKKA VLYRSLFGDS
460 470 480
AVRYPPYSRG KLRLLKALVD SNIFDLFKVL LGLA
Note: Major isoform.
Length:484
Mass (Da):53,159
Last modified:October 31, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5D931EF77293F668
GO
Isoform beta (identifier: Q70DU8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-71: MAAKKVFGSA...KPELESSVYE → MFYQQRVL

Note: Produced by alternative splicing. Maybe not translated into a protein or accumulates at a level below detection.Curated
Show »
Length:421
Mass (Da):46,215
Checksum:i867A5F299A010773
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti200I → V in CAE51203 (PubMed:15830124).Curated1
Sequence conflicti272A → D in CAE51203 (PubMed:15830124).Curated1
Sequence conflicti300F → L in CAE51203 (PubMed:15830124).Curated1
Sequence conflicti391A → T in AAM61211 (Ref. 4) Curated1
Sequence conflicti435F → S in CAE51203 (PubMed:15830124).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0548691 – 71MAAKK…SSVYE → MFYQQRVL in isoform beta. CuratedAdd BLAST71

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC074228 Genomic DNA Translation: AAG50550.1
CP002684 Genomic DNA Translation: AEE32025.1
CP002684 Genomic DNA Translation: AEE32026.1
CP002684 Genomic DNA Translation: AEE32027.1
AY072122 mRNA Translation: AAL59944.1
AY084648 mRNA Translation: AAM61211.1
AJ585241 mRNA Translation: CAE51203.1

Protein sequence database of the Protein Information Resource

More...
PIRi
H96505

NCBI Reference Sequences

More...
RefSeqi
NP_001077676.1, NM_001084207.1 [Q70DU8-2]
NP_175081.1, NM_103541.3 [Q70DU8-1]
NP_849770.1, NM_179439.4 [Q70DU8-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G44170.1; AT1G44170.1; AT1G44170 [Q70DU8-1]
AT1G44170.2; AT1G44170.2; AT1G44170 [Q70DU8-1]
AT1G44170.3; AT1G44170.3; AT1G44170 [Q70DU8-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
841020

Gramene; a comparative resource for plants

More...
Gramenei
AT1G44170.1; AT1G44170.1; AT1G44170 [Q70DU8-1]
AT1G44170.2; AT1G44170.2; AT1G44170 [Q70DU8-1]
AT1G44170.3; AT1G44170.3; AT1G44170 [Q70DU8-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G44170

Keywords - Coding sequence diversityi

Alternative promoter usage, Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC074228 Genomic DNA Translation: AAG50550.1
CP002684 Genomic DNA Translation: AEE32025.1
CP002684 Genomic DNA Translation: AEE32026.1
CP002684 Genomic DNA Translation: AEE32027.1
AY072122 mRNA Translation: AAL59944.1
AY084648 mRNA Translation: AAM61211.1
AJ585241 mRNA Translation: CAE51203.1
PIRiH96505
RefSeqiNP_001077676.1, NM_001084207.1 [Q70DU8-2]
NP_175081.1, NM_103541.3 [Q70DU8-1]
NP_849770.1, NM_179439.4 [Q70DU8-1]

3D structure databases

SMRiQ70DU8
ModBaseiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G44170.2

PTM databases

iPTMnetiQ70DU8

Proteomic databases

PaxDbiQ70DU8
PRIDEiQ70DU8
ProteomicsDBi244811 [Q70DU8-1]

Genome annotation databases

EnsemblPlantsiAT1G44170.1; AT1G44170.1; AT1G44170 [Q70DU8-1]
AT1G44170.2; AT1G44170.2; AT1G44170 [Q70DU8-1]
AT1G44170.3; AT1G44170.3; AT1G44170 [Q70DU8-2]
GeneIDi841020
GrameneiAT1G44170.1; AT1G44170.1; AT1G44170 [Q70DU8-1]
AT1G44170.2; AT1G44170.2; AT1G44170 [Q70DU8-1]
AT1G44170.3; AT1G44170.3; AT1G44170 [Q70DU8-2]
KEGGiath:AT1G44170

Organism-specific databases

AraportiAT1G44170
TAIRilocus:2205851, AT1G44170

Phylogenomic databases

eggNOGiKOG2456, Eukaryota
HOGENOMiCLU_005391_3_1_1
InParanoidiQ70DU8
OMAiRHGKRWM
PhylomeDBiQ70DU8

Enzyme and pathway databases

BioCyciARA:AT1G44170-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q70DU8

Gene expression databases

ExpressionAtlasiQ70DU8, baseline and differential
GenevisibleiQ70DU8, AT

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 1 hit
InterProiView protein in InterPro
IPR016161, Ald_DH/histidinol_DH
IPR016163, Ald_DH_C
IPR029510, Ald_DH_CS_GLU
IPR016162, Ald_DH_N
IPR015590, Aldehyde_DH_dom
IPR012394, Aldehyde_DH_NAD(P)
PfamiView protein in Pfam
PF00171, Aldedh, 1 hit
PIRSFiPIRSF036492, ALDH, 1 hit
SUPFAMiSSF53720, SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAL3H1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q70DU8
Secondary accession number(s): A8MQF0, Q8LFT7, Q9C6Y7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: October 31, 2006
Last modified: December 2, 2020
This is version 129 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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