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Protein

60S ribosomal protein L10

Gene

Rpl10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, Ribonucleoprotein, Ribosomal protein
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L10Curated
Alternative name(s):
Protein QM homolog
Ribosomal protein L10Imported
Gene namesi
Name:Rpl10Imported
Synonyms:Qm
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componentsi: Chromosome 9, Chromosome X

Organism-specific databases

MGIiMGI:105943 Rpl10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001471071 – 21460S ribosomal protein L10Add BLAST214

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei32Citrulline1 Publication1
Cross-linki175Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki188Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Post-translational modificationi

Citrullinated by PADI4.1 Publication

Keywords - PTMi

Citrullination, Isopeptide bond, Ubl conjugation

Proteomic databases

EPDiQ6ZWV3
MaxQBiQ6ZWV3
PaxDbiQ6ZWV3
PeptideAtlasiQ6ZWV3
PRIDEiQ6ZWV3
TopDownProteomicsiQ6ZWV3

PTM databases

iPTMnetiQ6ZWV3
PhosphoSitePlusiQ6ZWV3
SwissPalmiQ6ZWV3

Expressioni

Gene expression databases

BgeeiENSMUSG00000008682
CleanExiMM_RPL10
ExpressionAtlasiQ6ZWV3 baseline and differential
GenevisibleiQ6ZWV3 MM

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).By similarity

Protein-protein interaction databases

BioGridi226050, 3 interactors
IntActiQ6ZWV3, 5 interactors
MINTiQ6ZWV3
STRINGi10090.ENSMUSP00000125806

Structurei

3D structure databases

ProteinModelPortaliQ6ZWV3
SMRiQ6ZWV3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0857 Eukaryota
COG0197 LUCA
GeneTreeiENSGT00390000003897
HOVERGENiHBG002287
InParanoidiQ6ZWV3
KOiK02866
OMAiPYTRKEY
OrthoDBiEOG091G0H9M
PhylomeDBiQ6ZWV3
TreeFamiTF300082

Family and domain databases

CDDicd01433 Ribosomal_L16_L10e, 1 hit
Gene3Di3.90.1170.10, 1 hit
InterProiView protein in InterPro
IPR001197 Ribosomal_L10e
IPR016180 Ribosomal_L10e/L16
IPR036920 Ribosomal_L10e/L16_sf
IPR018255 Ribosomal_L10e_CS
PANTHERiPTHR11726 PTHR11726, 1 hit
PfamiView protein in Pfam
PF00252 Ribosomal_L16, 1 hit
PIRSFiPIRSF005590 Ribosomal_L10, 1 hit
SUPFAMiSSF54686 SSF54686, 1 hit
TIGRFAMsiTIGR00279 uL16_euk_arch, 1 hit
PROSITEiView protein in PROSITE
PS01257 RIBOSOMAL_L10E, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ZWV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG
60 70 80 90 100
HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN
110 120 130 140 150
KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE
160 170 180 190 200
ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI
210
PNRGPLDKWR ALHS
Length:214
Mass (Da):24,604
Last modified:January 23, 2007 - v3
Checksum:i0860CECC91DF74FE
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti150E → G in AAH86917 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M93980 mRNA Translation: AAA16894.1
X75312 mRNA Translation: CAA53061.1
AK011022 mRNA Translation: BAB27339.1
AK012561 mRNA Translation: BAB28316.1
AK014054 mRNA Translation: BAB29134.1
AK088777 mRNA Translation: BAC40566.1
AK144831 mRNA Translation: BAE26087.1
AK146217 mRNA Translation: BAE26985.1
AK151416 mRNA Translation: BAE30381.1
AK151655 mRNA Translation: BAE30584.1
AK151736 mRNA Translation: BAE30650.1
AK152123 mRNA Translation: BAE30965.1
AK152854 mRNA Translation: BAE31547.1
AK153345 mRNA Translation: BAE31921.1
AK160618 mRNA Translation: BAE35918.1
AK166610 mRNA Translation: BAE38892.1
AK167239 mRNA Translation: BAE39361.1
AK167966 mRNA Translation: BAE39963.1
AK168854 mRNA Translation: BAE40675.1
CH466519 Genomic DNA Translation: EDL27744.1
CH466650 Genomic DNA Translation: EDL29836.1
BC024901 mRNA Translation: AAH24901.1
BC048872 mRNA Translation: AAH48872.1
BC082293 mRNA Translation: AAH82293.1
BC083327 mRNA Translation: AAH83327.1
BC086917 mRNA Translation: AAH86917.1
BC092383 mRNA Translation: AAH92383.1
BC098204 mRNA Translation: AAH98204.1
BC099437 mRNA Translation: AAH99437.1
CCDSiCCDS41019.1
PIRiJC2013
RefSeqiNP_443067.1, NM_052835.3
UniGeneiMm.100113
Mm.315052
Mm.352201
Mm.472707

Genome annotation databases

EnsembliENSMUST00000008826; ENSMUSP00000008826; ENSMUSG00000008682
ENSMUST00000074085; ENSMUSP00000082055; ENSMUSG00000008682
ENSMUST00000076364; ENSMUSP00000125806; ENSMUSG00000058443
GeneIDi110954
KEGGimmu:110954
UCSCiuc009toc.2 mouse

Similar proteinsi

Entry informationi

Entry nameiRL10_MOUSE
AccessioniPrimary (citable) accession number: Q6ZWV3
Secondary accession number(s): P45634, Q569M8, Q5M9K8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 137 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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