Rpl10

Functionⁱ

Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.By similarity

GO - Molecular functionⁱ

RNA binding Source: GO_Central
structural constituent of ribosome Source: UniProtKB
translation regulator activity Source: UniProtKB

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

embryonic brain development Source: UniProtKB
negative regulation of apoptotic process Source: MGI
negative regulation of transcription by RNA polymerase II Source: MGI
regulation of translation Source: UniProtKB
ribosomal large subunit assembly Source: GO_Central
translation Source: MGI

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental protein, Ribonucleoprotein, Ribosomal protein
Biological process	Translation regulation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: 60S ribosomal protein L10Curated Alternative name(s): Protein QM homolog Ribosomal protein L10Imported
Gene namesⁱ	Name:Rpl10Imported Synonyms:Qm
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentsⁱ: Chromosome 9, Chromosome X

Organism-specific databases

MGIⁱ	MGI:105943 Rpl10

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000147107	1 – 214	60S ribosomal protein L10Add BLAST		214

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	32	Citrulline1 Publication	1
Cross-linkⁱ	175	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	188	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)By similarity

Post-translational modificationⁱ

Citrullinated by PADI4.1 Publication

Keywords - PTMⁱ

Citrullination, Isopeptide bond, Ubl conjugation

Proteomic databases

EPDⁱ	Q6ZWV3
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q6ZWV3
PaxDbⁱ	Q6ZWV3
PeptideAtlas More...PeptideAtlasⁱ	Q6ZWV3
PRIDEⁱ	Q6ZWV3
TopDownProteomicsⁱ	Q6ZWV3

PTM databases

iPTMnetⁱ	Q6ZWV3
PhosphoSitePlusⁱ	Q6ZWV3
SwissPalmⁱ	Q6ZWV3

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000008682
CleanExⁱ	MM_RPL10
ExpressionAtlasⁱ	Q6ZWV3 baseline and differential
Genevisibleⁱ	Q6ZWV3 MM

Interactionⁱ

Subunit structureⁱ

Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).By similarity

Protein-protein interaction databases

BioGridⁱ	226050, 3 interactors
IntActⁱ	Q6ZWV3, 5 interactors
Molecular INTeraction database More...MINTⁱ	Q6ZWV3
STRINGⁱ	10090.ENSMUSP00000125806

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q6ZWV3
SMRⁱ	Q6ZWV3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the universal ribosomal protein uL16 family.Curated

Phylogenomic databases

eggNOGⁱ	KOG0857 Eukaryota COG0197 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000003897
HOVERGENⁱ	HBG002287
InParanoidⁱ	Q6ZWV3
KEGG Orthology (KO) More...KOⁱ	K02866
OMAⁱ	PYTRKEY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H9M
PhylomeDBⁱ	Q6ZWV3
TreeFamⁱ	TF300082

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01433 Ribosomal_L16_L10e, 1 hit
Gene3Dⁱ	3.90.1170.10, 1 hit
InterProⁱ	View protein in InterPro IPR001197 Ribosomal_L10e IPR016180 Ribosomal_L10e/L16 IPR036920 Ribosomal_L10e/L16_sf IPR018255 Ribosomal_L10e_CS
PANTHERⁱ	PTHR11726 PTHR11726, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00252 Ribosomal_L16, 1 hit
PIRSFⁱ	PIRSF005590 Ribosomal_L10, 1 hit
SUPFAMⁱ	SSF54686 SSF54686, 1 hit
TIGRFAMsⁱ	TIGR00279 uL16_euk_arch, 1 hit
PROSITEⁱ	View protein in PROSITE PS01257 RIBOSOMAL_L10E, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q6ZWV3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGRRPARCYR YCKNKPYPKS RFCRGVPDAK IRIFDLGRKK AKVDEFPLCG 
        60         70         80         90        100
HMVSDEYEQL SSEALEAARI CANKYMVKSC GKDGFHIRVR LHPFHVIRIN 
       110        120        130        140        150
KMLSCAGADR LQTGMRGAFG KPQGTVARVH IGQVIMSIRT KLQNKEHVIE 
       160        170        180        190        200
ALRRAKFKFP GRQKIHISKK WGFTKFNADE FEDMVAEKRL IPDGCGVKYI 
       210 
PNRGPLDKWR ALHS

Length:214

Mass (Da):24,604

Last modified:January 23, 2007 - v3

Checksum:ⁱ0860CECC91DF74FE

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	150	E → G in AAH86917 (PubMed:15489334).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M93980 mRNA Translation: AAA16894.1 X75312 mRNA Translation: CAA53061.1 AK011022 mRNA Translation: BAB27339.1 AK012561 mRNA Translation: BAB28316.1 AK014054 mRNA Translation: BAB29134.1 AK088777 mRNA Translation: BAC40566.1 AK144831 mRNA Translation: BAE26087.1 AK146217 mRNA Translation: BAE26985.1 AK151416 mRNA Translation: BAE30381.1 AK151655 mRNA Translation: BAE30584.1 AK151736 mRNA Translation: BAE30650.1 AK152123 mRNA Translation: BAE30965.1 AK152854 mRNA Translation: BAE31547.1 AK153345 mRNA Translation: BAE31921.1 AK160618 mRNA Translation: BAE35918.1 AK166610 mRNA Translation: BAE38892.1 AK167239 mRNA Translation: BAE39361.1 AK167966 mRNA Translation: BAE39963.1 AK168854 mRNA Translation: BAE40675.1 CH466519 Genomic DNA Translation: EDL27744.1 CH466650 Genomic DNA Translation: EDL29836.1 BC024901 mRNA Translation: AAH24901.1 BC048872 mRNA Translation: AAH48872.1 BC082293 mRNA Translation: AAH82293.1 BC083327 mRNA Translation: AAH83327.1 BC086917 mRNA Translation: AAH86917.1 BC092383 mRNA Translation: AAH92383.1 BC098204 mRNA Translation: AAH98204.1 BC099437 mRNA Translation: AAH99437.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41019.1
PIRⁱ	JC2013
NCBI Reference Sequences More...RefSeqⁱ	NP_443067.1, NM_052835.3
UniGeneⁱ	Mm.100113 Mm.315052 Mm.352201 Mm.472707

Genome annotation databases

Ensemblⁱ	ENSMUST00000008826; ENSMUSP00000008826; ENSMUSG00000008682 ENSMUST00000074085; ENSMUSP00000082055; ENSMUSG00000008682 ENSMUST00000076364; ENSMUSP00000125806; ENSMUSG00000058443
GeneIDⁱ	110954
KEGGⁱ	mmu:110954
UCSC genome browser More...UCSCⁱ	uc009toc.2 mouse

Protein	Similar proteins		Species	Score	Length
Q6ZWV3	60S ribosomal protein L10	)	HUMAN		214
60S ribosomal protein L10		PAPAN		214
60S ribosomal protein L10		RAT		214
60S ribosomal protein L10		Daphnia magna		214
Ribosomal protein L10 (Predicted)		CALJA		214
+43

Protein	Similar proteins		Species	Score	Length
Q6ZWV3	60S ribosomal protein L10	)	HUMAN		214
60S ribosomal protein L10		PAPAN		214
60S ribosomal protein L10		RAT		214
60S ribosomal protein L10		Daphnia magna		214
Ribosomal protein L10 (Predicted)		CALJA		214
+92

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M93980 mRNA Translation: AAA16894.1 X75312 mRNA Translation: CAA53061.1 AK011022 mRNA Translation: BAB27339.1 AK012561 mRNA Translation: BAB28316.1 AK014054 mRNA Translation: BAB29134.1 AK088777 mRNA Translation: BAC40566.1 AK144831 mRNA Translation: BAE26087.1 AK146217 mRNA Translation: BAE26985.1 AK151416 mRNA Translation: BAE30381.1 AK151655 mRNA Translation: BAE30584.1 AK151736 mRNA Translation: BAE30650.1 AK152123 mRNA Translation: BAE30965.1 AK152854 mRNA Translation: BAE31547.1 AK153345 mRNA Translation: BAE31921.1 AK160618 mRNA Translation: BAE35918.1 AK166610 mRNA Translation: BAE38892.1 AK167239 mRNA Translation: BAE39361.1 AK167966 mRNA Translation: BAE39963.1 AK168854 mRNA Translation: BAE40675.1 CH466519 Genomic DNA Translation: EDL27744.1 CH466650 Genomic DNA Translation: EDL29836.1 BC024901 mRNA Translation: AAH24901.1 BC048872 mRNA Translation: AAH48872.1 BC082293 mRNA Translation: AAH82293.1 BC083327 mRNA Translation: AAH83327.1 BC086917 mRNA Translation: AAH86917.1 BC092383 mRNA Translation: AAH92383.1 BC098204 mRNA Translation: AAH98204.1 BC099437 mRNA Translation: AAH99437.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS41019.1
PIRⁱ	JC2013
NCBI Reference Sequences More...RefSeqⁱ	NP_443067.1, NM_052835.3
UniGeneⁱ	Mm.100113 Mm.315052 Mm.352201 Mm.472707

3D structure databases

ProteinModelPortalⁱ	Q6ZWV3
SMRⁱ	Q6ZWV3
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	226050, 3 interactors
IntActⁱ	Q6ZWV3, 5 interactors
Molecular INTeraction database More...MINTⁱ	Q6ZWV3
STRINGⁱ	10090.ENSMUSP00000125806

PTM databases

iPTMnetⁱ	Q6ZWV3
PhosphoSitePlusⁱ	Q6ZWV3
SwissPalmⁱ	Q6ZWV3

Proteomic databases

EPDⁱ	Q6ZWV3
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q6ZWV3
PaxDbⁱ	Q6ZWV3
PeptideAtlas More...PeptideAtlasⁱ	Q6ZWV3
PRIDEⁱ	Q6ZWV3
TopDownProteomicsⁱ	Q6ZWV3

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000008826; ENSMUSP00000008826; ENSMUSG00000008682 ENSMUST00000074085; ENSMUSP00000082055; ENSMUSG00000008682 ENSMUST00000076364; ENSMUSP00000125806; ENSMUSG00000058443
GeneIDⁱ	110954
KEGGⁱ	mmu:110954
UCSC genome browser More...UCSCⁱ	uc009toc.2 mouse

Organism-specific databases

CTDⁱ	6134
MGIⁱ	MGI:105943 Rpl10

Phylogenomic databases

eggNOGⁱ	KOG0857 Eukaryota COG0197 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000003897
HOVERGENⁱ	HBG002287
InParanoidⁱ	Q6ZWV3
KEGG Orthology (KO) More...KOⁱ	K02866
OMAⁱ	PYTRKEY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0H9M
PhylomeDBⁱ	Q6ZWV3
TreeFamⁱ	TF300082

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q6ZWV3
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000008682
CleanExⁱ	MM_RPL10
ExpressionAtlasⁱ	Q6ZWV3 baseline and differential
Genevisibleⁱ	Q6ZWV3 MM

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd01433 Ribosomal_L16_L10e, 1 hit
Gene3Dⁱ	3.90.1170.10, 1 hit
InterProⁱ	View protein in InterPro IPR001197 Ribosomal_L10e IPR016180 Ribosomal_L10e/L16 IPR036920 Ribosomal_L10e/L16_sf IPR018255 Ribosomal_L10e_CS
PANTHERⁱ	PTHR11726 PTHR11726, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00252 Ribosomal_L16, 1 hit
PIRSFⁱ	PIRSF005590 Ribosomal_L10, 1 hit
SUPFAMⁱ	SSF54686 SSF54686, 1 hit
TIGRFAMsⁱ	TIGR00279 uL16_euk_arch, 1 hit
PROSITEⁱ	View protein in PROSITE PS01257 RIBOSOMAL_L10E, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RL10_MOUSE
Accessionⁱ	Q6ZWV3Primary (citable) accession number: Q6ZWV3 Secondary accession number(s): P45634, Q569M8, Q5M9K8
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 19, 2004
	Last sequence update:	January 23, 2007
	Last modified:	May 23, 2018
	This is version 137 of the entry and version 3 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
Ribosomal proteins
Ribosomal proteins families and list of entries
SIMILARITY comments
Index of protein domains and families

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q6ZWV3 (RL10_MOUSE)

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60S ribosomal protein L10

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

Endoplasmic reticulum

Nucleus

Other locations

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ