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UniProtKB - Q6ZWT7 (MBOA2_HUMAN)

Entry version 111 (11 Dec 2019)
Sequence version 2 (03 Apr 2007)
Previous versions | rss
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Protein

Lysophospholipid acyltransferase 2

Gene

MBOAT2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidic acid (LPA) into phosphatidic acid (PA) (LPAAT activity). Has also a very weak lysophosphatidylcholine acyltransferase (LPCAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Partially inhibited by thimerosal.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: phospholipid metabolism

This protein is involved in the pathway phospholipid metabolism, which is part of Lipid metabolism.
View all proteins of this organism that are known to be involved in the pathway phospholipid metabolism and in Lipid metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei342By similarity1
Active sitei373By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.3.1.23 2681

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-HSA-1482788 Acyl chain remodelling of PC
R-HSA-1482839 Acyl chain remodelling of PE

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00085

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...SwissLipidsi		SLP:000000134

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lysophospholipid acyltransferase 2 (EC:2.3.1.-)
Short name:
LPLAT 2
Alternative name(s):
1-acylglycerophosphate O-acyltransferase (EC:2.3.1.51)
1-acylglycerophosphoethanolamine O-acyltransferase (EC:2.3.1.n7)
Lysophosphatidic acid acyltransferase
Short name:
LPAAT
Short name:
Lyso-PA acyltransferase
Lysophosphatidylethanolamine acyltransferase
Short name:
LPEAT
Short name:
Lyso-PE acyltransferase
Membrane-bound O-acyltransferase domain-containing protein 2
Short name:
O-acyltransferase domain-containing protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MBOAT2
Synonyms:OACT2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000143797.11

Human Gene Nomenclature Database

More...HGNCi		HGNC:25193 MBOAT2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		611949 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6ZWT7

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei22 – 42HelicalSequence analysisAdd BLAST21
Transmembranei61 – 81HelicalSequence analysisAdd BLAST21
Transmembranei88 – 108HelicalSequence analysisAdd BLAST21
Transmembranei184 – 204HelicalSequence analysisAdd BLAST21
Transmembranei237 – 257HelicalSequence analysisAdd BLAST21
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Transmembranei366 – 386HelicalSequence analysisAdd BLAST21
Transmembranei416 – 436HelicalSequence analysisAdd BLAST21
Transmembranei444 – 464HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		129642

Open Targets

More...OpenTargetsi		ENSG00000143797

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134987740

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6ZWT7 Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MBOAT2

Domain mapping of disease mutations (DMDM)

More...DMDMi		143811417

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002730201 – 520Lysophospholipid acyltransferase 2Add BLAST520

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6ZWT7

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6ZWT7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6ZWT7

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6ZWT7

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6ZWT7

PeptideAtlas

More...PeptideAtlasi		Q6ZWT7

PRoteomics IDEntifications database

More...PRIDEi		Q6ZWT7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		68497

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6ZWT7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6ZWT7

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q6ZWT7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in neutrophils.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000143797 Expressed in 222 organ(s), highest expression level in corpus callosum

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6ZWT7 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6ZWT7 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA014836

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		126201, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q6ZWT7, 3 interactors

Molecular INTeraction database

More...MINTi		Q6ZWT7

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000302177

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6ZWT7 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the membrane-bound acyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2704 Eukaryota
COG5202 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00950000182735

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000015994

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6ZWT7

KEGG Orthology (KO)

More...KOi		K13517

Identification of Orthologs from Complete Genome Data

More...OMAi		SFLDNWN

Database of Orthologous Groups

More...OrthoDBi		881262at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6ZWT7

TreeFam database of animal gene trees

More...TreeFami		TF314906

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004299 MBOAT_fam

Pfam protein domain database

More...Pfami		View protein in Pfam
PF03062 MBOAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6ZWT7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATTSTTGST LLQPLSNAVQ LPIDQVNFVV CQLFALLAAI WFRTYLHSSK 
        60         70         80         90        100
TSSFIRHVVA TLLGLYLALF CFGWYALHFL VQSGISYCIM IIIGVENMHN 
       110        120        130        140        150
YCFVFALGYL TVCQVTRVYI FDYGQYSADF SGPMMIITQK ITSLACEIHD 
       160        170        180        190        200
GMFRKDEELT SSQRDLAVRR MPSLLEYLSY NCNFMGILAG PLCSYKDYIT 
       210        220        230        240        250
FIEGRSYHIT QSGENGKEET QYERTEPSPN TAVVQKLLVC GLSLLFHLTI 
       260        270        280        290        300
CTTLPVEYNI DEHFQATASW PTKIIYLYIS LLAARPKYYF AWTLADAINN 
       310        320        330        340        350
AAGFGFRGYD ENGAARWDLI SNLRIQQIEM STSFKMFLDN WNIQTALWLK 
       360        370        380        390        400
RVCYERTSFS PTIQTFILSA IWHGVYPGYY LTFLTGVLMT LAARAMRNNF 
       410        420        430        440        450
RHYFIEPSQL KLFYDVITWI VTQVAISYTV VPFVLLSIKP SLTFYSSWYY 
       460        470        480        490        500
CLHILGILVL LLLPVKKTQR RKNTHENIQL SQSKKFDEGE NSLGQNSFST 
       510        520
TNNVCNQNQE IASRHSSLKQ
Length:520
Mass (Da):59,527
Last modified:April 3, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i27FFC44815B21288
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C5D1H7C5D1_HUMAN
Lysophospholipid acyltransferase 2
MBOAT2
158Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J2H7C9J2H7_HUMAN
Lysophospholipid acyltransferase 2
MBOAT2
176Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WDJ6F8WDJ6_HUMAN
Lysophospholipid acyltransferase 2
MBOAT2
46Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC11204 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti402H → R in BAC11204 (PubMed:16303743).Curated1
Sequence conflicti484K → R in BAC85105 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_030068501T → A. Corresponds to variant dbSNP:rs16866827Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB305044 mRNA Translation: BAF93900.1
AK027321 mRNA Translation: BAC85105.1
AC012495 Genomic DNA No translation available.
AC112723 Genomic DNA No translation available.
BC016005 mRNA Translation: AAH16005.1
BC146871 mRNA Translation: AAI46872.1
BC157827 mRNA Translation: AAI57828.1
AK074779 mRNA Translation: BAC11204.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS1660.1

NCBI Reference Sequences

More...RefSeqi		NP_001308194.1, NM_001321265.1
NP_001308195.1, NM_001321266.1
NP_001308196.1, NM_001321267.1
NP_620154.2, NM_138799.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000305997; ENSP00000302177; ENSG00000143797

Database of genes from NCBI RefSeq genomes

More...GeneIDi		129642

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:129642

UCSC genome browser

More...UCSCi		uc002qzg.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB305044 mRNA Translation: BAF93900.1
AK027321 mRNA Translation: BAC85105.1
AC012495 Genomic DNA No translation available.
AC112723 Genomic DNA No translation available.
BC016005 mRNA Translation: AAH16005.1
BC146871 mRNA Translation: AAI46872.1
BC157827 mRNA Translation: AAI57828.1
AK074779 mRNA Translation: BAC11204.1 Different initiation.
CCDSiCCDS1660.1
RefSeqiNP_001308194.1, NM_001321265.1
NP_001308195.1, NM_001321266.1
NP_001308196.1, NM_001321267.1
NP_620154.2, NM_138799.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi126201, 3 interactors
IntActiQ6ZWT7, 3 interactors
MINTiQ6ZWT7
STRINGi9606.ENSP00000302177

Chemistry databases

SwissLipidsiSLP:000000134

PTM databases

iPTMnetiQ6ZWT7
PhosphoSitePlusiQ6ZWT7
SwissPalmiQ6ZWT7

Polymorphism and mutation databases

BioMutaiMBOAT2
DMDMi143811417

Proteomic databases

EPDiQ6ZWT7
jPOSTiQ6ZWT7
MassIVEiQ6ZWT7
MaxQBiQ6ZWT7
PaxDbiQ6ZWT7
PeptideAtlasiQ6ZWT7
PRIDEiQ6ZWT7
ProteomicsDBi68497

Genome annotation databases

EnsembliENST00000305997; ENSP00000302177; ENSG00000143797
GeneIDi129642
KEGGihsa:129642
UCSCiuc002qzg.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		129642
DisGeNETi129642
EuPathDBiHostDB:ENSG00000143797.11

GeneCards: human genes, protein and diseases

More...GeneCardsi		MBOAT2
HGNCiHGNC:25193 MBOAT2
HPAiHPA014836
MIMi611949 gene
neXtProtiNX_Q6ZWT7
OpenTargetsiENSG00000143797
PharmGKBiPA134987740

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2704 Eukaryota
COG5202 LUCA
GeneTreeiENSGT00950000182735
HOGENOMiHOG000015994
InParanoidiQ6ZWT7
KOiK13517
OMAiSFLDNWN
OrthoDBi881262at2759
PhylomeDBiQ6ZWT7
TreeFamiTF314906

Enzyme and pathway databases

UniPathwayiUPA00085
BRENDAi2.3.1.23 2681
ReactomeiR-HSA-1482788 Acyl chain remodelling of PC
R-HSA-1482839 Acyl chain remodelling of PE

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MBOAT2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		129642
PharosiQ6ZWT7 Tbio

Protein Ontology

More...PROi		PR:Q6ZWT7
RNActiQ6ZWT7 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000143797 Expressed in 222 organ(s), highest expression level in corpus callosum
ExpressionAtlasiQ6ZWT7 baseline and differential
GenevisibleiQ6ZWT7 HS

Family and domain databases

InterProiView protein in InterPro
IPR004299 MBOAT_fam
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMBOA2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZWT7
Secondary accession number(s): A9EDR2, Q8NCE7, Q96KY4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: April 3, 2007
Last modified: December 11, 2019
This is version 111 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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