Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Uncharacterized protein C16orf86

Gene

C16orf86

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized protein C16orf86
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 16

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000159761.14

Human Gene Nomenclature Database

More...
HGNCi
HGNC:33755 C16orf86

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZW13

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000159761

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162378445

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C16orf86

Domain mapping of disease mutations (DMDM)

More...
DMDMi
313104092

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003189611 – 317Uncharacterized protein C16orf86Add BLAST317

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZW13

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZW13

PeptideAtlas

More...
PeptideAtlasi
Q6ZW13

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZW13

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68452

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZW13

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZW13

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000159761 Expressed in 141 organ(s), highest expression level in left testis

CleanEx database of gene expression profiles

More...
CleanExi
HS_C16orf86

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZW13 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZW13 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA073475

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q6ZW13

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410JA3Y Eukaryota
ENOG4111BZQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011138

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000074126

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG098407

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZW13

Identification of Orthologs from Complete Genome Data

More...
OMAi
VDINKML

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0QRM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZW13

TreeFam database of animal gene trees

More...
TreeFami
TF337136

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031516 DUF4691

The PANTHER Classification System

More...
PANTHERi
PTHR37867 PTHR37867, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15762 DUF4691, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6ZW13-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASAGAERRP GVQEATVVGQ GQLTEEPGSA QTSECPVAGD QFLVPAHEAR
60 70 80 90 100
GTQSEDQRPA GAASESELQE EGPKLGEERP KPHAGALEER GPRPVVSIVR
110 120 130 140 150
PRHGPKRKPV KSLSLPGLRA HLKAEAELPP KLPLQEEEPE DSQSEPSPSA
160 170 180 190 200
KQHKKAKKRK SLGAPVLHAV ASMVSAPLET LRLERKAQRL RPLYQYVNYC
210 220 230 240 250
NPELNQAGKG DGEAEVEAEA ELAPVPEEGG VEQLQALLPL AGELGPGLAL
260 270 280 290 300
PCPSPLVTPT HALAPLGEEA GEEPGGLPSL GVSDHKAEVD KSTQVDIDKM
310
LSVCTAPLVP PLSPQYK
Length:317
Mass (Da):33,511
Last modified:November 30, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7F42A5AC1B0A16F0
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087X1J0A0A087X1J0_HUMAN
Uncharacterized protein C16orf86
C16orf86
170Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
R4GNF0R4GNF0_HUMAN
Uncharacterized protein C16orf86
C16orf86
198Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WFD6F8WFD6_HUMAN
Uncharacterized protein C16orf86
C16orf86
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC85694 differs from that shown. Intron retention.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK123796 mRNA Translation: BAC85694.1 Sequence problems.
AC010530 Genomic DNA No translation available.
CH471092 Genomic DNA Translation: EAW83162.1
CH471092 Genomic DNA Translation: EAW83163.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS32468.2

NCBI Reference Sequences

More...
RefSeqi
NP_001013002.2, NM_001012984.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.632208

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000403458; ENSP00000384117; ENSG00000159761

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
388284

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:388284

UCSC genome browser

More...
UCSCi
uc002ety.4 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK123796 mRNA Translation: BAC85694.1 Sequence problems.
AC010530 Genomic DNA No translation available.
CH471092 Genomic DNA Translation: EAW83162.1
CH471092 Genomic DNA Translation: EAW83163.1
CCDSiCCDS32468.2
RefSeqiNP_001013002.2, NM_001012984.2
UniGeneiHs.632208

3D structure databases

ProteinModelPortaliQ6ZW13
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ6ZW13
PhosphoSitePlusiQ6ZW13

Polymorphism and mutation databases

BioMutaiC16orf86
DMDMi313104092

Proteomic databases

MaxQBiQ6ZW13
PaxDbiQ6ZW13
PeptideAtlasiQ6ZW13
PRIDEiQ6ZW13
ProteomicsDBi68452

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000403458; ENSP00000384117; ENSG00000159761
GeneIDi388284
KEGGihsa:388284
UCSCiuc002ety.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
388284
EuPathDBiHostDB:ENSG00000159761.14

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C16orf86
HGNCiHGNC:33755 C16orf86
HPAiHPA073475
neXtProtiNX_Q6ZW13
OpenTargetsiENSG00000159761
PharmGKBiPA162378445

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410JA3Y Eukaryota
ENOG4111BZQ LUCA
GeneTreeiENSGT00390000011138
HOGENOMiHOG000074126
HOVERGENiHBG098407
InParanoidiQ6ZW13
OMAiVDINKML
OrthoDBiEOG091G0QRM
PhylomeDBiQ6ZW13
TreeFamiTF337136

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
388284

Protein Ontology

More...
PROi
PR:Q6ZW13

Gene expression databases

BgeeiENSG00000159761 Expressed in 141 organ(s), highest expression level in left testis
CleanExiHS_C16orf86
ExpressionAtlasiQ6ZW13 baseline and differential
GenevisibleiQ6ZW13 HS

Family and domain databases

InterProiView protein in InterPro
IPR031516 DUF4691
PANTHERiPTHR37867 PTHR37867, 1 hit
PfamiView protein in Pfam
PF15762 DUF4691, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCP086_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZW13
Secondary accession number(s): B5MCW6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: November 30, 2010
Last modified: November 7, 2018
This is version 86 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again