UniProtKB - Q6ZV29 (PLPL7_HUMAN)
Patatin-like phospholipase domain-containing protein 7
PNPLA7
Functioni
Lysophospholipase which preferentially deacylates unsaturated lysophosphatidylcholine (C18:1), generating glycerophosphocholine. Also can deacylate, to a lesser extent, lysophosphatidylethanolamine (C18:1), lysophosphatidyl-L-serine (C18:1) and lysophosphatidic acid (C16:0).
By similarityCatalytic activityi
- a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid + H+ + sn-glycerol 3-phosphocholineBy similarityEC:3.1.1.5By similarityThis reaction proceeds in the forwardBy similarity direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H2O = (9Z)-octadecenoate + H+ + sn-glycerol 3-phosphocholineBy similarityThis reaction proceeds in the forwardBy similarity direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H2O = (9Z)-octadecenoate + H+ + sn-glycero-3-phosphoethanolamineBy similarityThis reaction proceeds in the forwardBy similarity direction.
- 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = (9Z)-octadecenoate + H+ + sn-glycero-3-phospho-L-serineBy similarityThis reaction proceeds in the forwardBy similarity direction.
- 1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = H+ + hexadecanoate + sn-glycerol 3-phosphocholineBy similarityThis reaction proceeds in the forwardBy similarity direction.
- 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = H+ + hexadecanoate + sn-glycerol 3-phosphateBy similarityThis reaction proceeds in the forwardBy similarity direction.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 961 | NucleophilePROSITE-ProRule annotation | 1 | |
Active sitei | 1081 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 145 – 272 | cNMP 1PROSITE-ProRule annotationAdd BLAST | 128 | |
Nucleotide bindingi | 458 – 563 | cNMP 2PROSITE-ProRule annotationAdd BLAST | 106 | |
Nucleotide bindingi | 591 – 696 | cNMP 3PROSITE-ProRule annotationAdd BLAST | 106 |
GO - Molecular functioni
- lysophospholipase activity Source: GO_Central
- phosphatidyl phospholipase B activity Source: UniProtKB-EC
GO - Biological processi
- phosphatidylcholine catabolic process Source: Ensembl
Keywordsi
Molecular function | Hydrolase |
Biological process | Lipid degradation, Lipid metabolism |
Enzyme and pathway databases
PathwayCommonsi | Q6ZV29 |
Reactomei | R-HSA-6814848, Glycerophospholipid catabolism |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:PNPLA7 Synonyms:C9orf111 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:24768, PNPLA7 |
MIMi | 612122, gene |
neXtProti | NX_Q6ZV29 |
VEuPathDBi | HostDB:ENSG00000130653 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane By similarity; Single-pass type III membrane protein By similarity
Other locations
- Lipid droplet By similarity
Endoplasmic reticulum
- endoplasmic reticulum Source: GO_Central
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
- lipid droplet Source: UniProtKB-SubCell
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 12 | LumenalCuratedAdd BLAST | 12 | |
Transmembranei | 13 – 33 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 34 – 1317 | CytoplasmicCuratedAdd BLAST | 1284 |
Keywords - Cellular componenti
Endoplasmic reticulum, Lipid droplet, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 375775 |
OpenTargetsi | ENSG00000130653 |
PharmGKBi | PA134935962 |
Miscellaneous databases
Pharosi | Q6ZV29, Tdark |
Genetic variation databases
BioMutai | PNPLA7 |
DMDMi | 296452996 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000293489 | 1 – 1317 | Patatin-like phospholipase domain-containing protein 7Add BLAST | 1317 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 355 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1258 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1262 | PhosphothreonineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q6ZV29 |
jPOSTi | Q6ZV29 |
MassIVEi | Q6ZV29 |
MaxQBi | Q6ZV29 |
PaxDbi | Q6ZV29 |
PeptideAtlasi | Q6ZV29 |
PRIDEi | Q6ZV29 |
ProteomicsDBi | 68378 [Q6ZV29-1] 68379 [Q6ZV29-2] 68380 [Q6ZV29-3] 68381 [Q6ZV29-4] 68382 [Q6ZV29-5] |
PTM databases
iPTMneti | Q6ZV29 |
PhosphoSitePlusi | Q6ZV29 |
Expressioni
Gene expression databases
Bgeei | ENSG00000130653, Expressed in prostate gland and 133 other tissues |
ExpressionAtlasi | Q6ZV29, baseline and differential |
Genevisiblei | Q6ZV29, HS |
Organism-specific databases
HPAi | ENSG00000130653, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 131999, 6 interactors |
STRINGi | 9606.ENSP00000384610 |
Miscellaneous databases
RNActi | Q6ZV29, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 928 – 1094 | PNPLAPROSITE-ProRule annotationAdd BLAST | 167 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 320 – 357 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 370 – 392 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 659 – 945 | Involved in the binding to lipid dropletsBy similarityAdd BLAST | 287 | |
Regioni | 1271 – 1317 | DisorderedSequence analysisAdd BLAST | 47 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 932 – 937 | GXGXXGPROSITE-ProRule annotation | 6 | |
Motifi | 959 – 963 | GXSXGPROSITE-ProRule annotation | 5 | |
Motifi | 1081 – 1083 | DGA/GPROSITE-ProRule annotation | 3 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 320 – 336 | Basic and acidic residuesSequence analysisAdd BLAST | 17 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2968, Eukaryota |
GeneTreei | ENSGT00940000156763 |
HOGENOMi | CLU_000960_1_0_1 |
InParanoidi | Q6ZV29 |
OMAi | FTMNFTT |
OrthoDBi | 253518at2759 |
PhylomeDBi | Q6ZV29 |
TreeFami | TF300519 |
Family and domain databases
CDDi | cd00038, CAP_ED, 3 hits |
Gene3Di | 2.60.120.10, 3 hits |
InterProi | View protein in InterPro IPR016035, Acyl_Trfase/lysoPLipase IPR018490, cNMP-bd-like IPR000595, cNMP-bd_dom IPR002641, PNPLA_dom IPR014710, RmlC-like_jellyroll |
Pfami | View protein in Pfam PF00027, cNMP_binding, 3 hits PF01734, Patatin, 1 hit |
SMARTi | View protein in SMART SM00100, cNMP, 3 hits |
SUPFAMi | SSF51206, SSF51206, 3 hits SSF52151, SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50042, CNMP_BINDING_3, 3 hits PS51635, PNPLA, 1 hit |
s (5+)i Sequence
Sequence statusi: Complete.
This entry describes 5 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 5 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEEEKDDSPQ LTGIAVGALL ALALVGVLIL FMFRRLRQFR QAQPTPQYRF
60 70 80 90 100
RKRDKVMFYG RKIMRKVTTL PNTLVENTAL PRQRARKRTK VLSLAKRILR
110 120 130 140 150
FKKEYPALQP KEPPPSLLEA DLTEFDVKNS HLPSEVLYML KNVRVLGHFE
160 170 180 190 200
KPLFLELCKH IVFVQLQEGE HVFQPREPDP SICVVQDGRL EVCIQDTDGT
210 220 230 240 250
EVVVKEVLAG DSVHSLLSIL DIITGHAAPY KTVSVRAAIP STILRLPAAA
260 270 280 290 300
FHGVFEKYPE TLVRVVQIIM VRLQRVTFLA LHNYLGLTTE LFNAESQAIP
310 320 330 340 350
LVSVASVAAG KAKKQVFYGE EERLKKPPRL QESCDSDHGG GRPAAAGPLL
360 370 380 390 400
KRSHSVPAPS IRKQILEELE KPGAGDPDPS APQGGPGSAT SDLGMACDRA
410 420 430 440 450
RVFLHSDEHP GSSVASKSRK SVMVAEIPST VSQHSESHTD ETLASRKSDA
460 470 480 490 500
IFRAAKKDLL TLMKLEDSSL LDGRVALLHV PAGTVVSRQG DQDASILFVV
510 520 530 540 550
SGLLHVYQRK IGSQEDTCLF LTRPGEMVGQ LAVLTGEPLI FTVKANRDCS
560 570 580 590 600
FLSISKAHFY EIMRKQPTVV LGVAHTVVKR MSSFVRQIDF ALDWVEVEAG
610 620 630 640 650
RAIYRQGDKS DCTYIMLSGR LRSVIRKDDG KKRLAGEYGR GDLVGVVETL
660 670 680 690 700
THQARATTVH AVRDSELAKL PAGALTSIKR RYPQVVTRLI HLLGEKILGS
710 720 730 740 750
LQQGPVTGHQ LGLPTEGSKW DLGNPAVNLS TVAVMPVSEE VPLTAFALEL
760 770 780 790 800
EHALSAIGPT LLLTSDNIKR RLGSAALDSV HEYRLSSWLG QQEDTHRIVL
810 820 830 840 850
YQADGTLTPW TQRCVRQADC ILIVGLGDQE PTVGELERML ESTAVRAQKQ
860 870 880 890 900
LILLHREEGP APARTVEWLN MRSWCSGHLH LCCPRRVFSR RSLPKLVEMY
910 920 930 940 950
KHVFQRPPDR HSDFSRLARV LTGNAIALVL GGGGARGCAQ VGVLKALAEC
960 970 980 990 1000
GIPVDMVGGT SIGAFVGALY SEERNYSQMR IRAKQWAEGM TSLMKAALDL
1010 1020 1030 1040 1050
TYPITSMFSG AGFNSSIFSV FKDQQIEDLW IPYFAITTDI TASAMRVHTD
1060 1070 1080 1090 1100
GSLWWYVRAS MSLSGYMPPL CDPKDGHLLM DGGYINNLPA DVARSMGAKV
1110 1120 1130 1140 1150
VIAIDVGSRD ETDLTNYGDA LSGWWLLWKR WNPLATKVKV LNMAEIQTRL
1160 1170 1180 1190 1200
AYVCCVRQLE VVKSSDYCEY LRPPIDSYST LDFGKFNEIC EVGYQHGRTV
1210 1220 1230 1240 1250
FDIWGRSGVL EKMLRDQQGP SKKPASAVLT CPNASFTDLA EIVSRIEPAK
1260 1270 1280 1290 1300
PAMVDDESDY QTEYEEELLD VPRDAYADFQ STSAQQGSDL EDESSLRHRH
1310
PSLAFPKLSE GSSDQDG
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF2Z2D4 | F2Z2D4_HUMAN | Patatin-like phospholipase domain-c... | PNPLA7 | 200 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 173 | F → L in BAC86509 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 326 | K → M in BAC86036 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 384 – 399 | Missing in BAC86509 (PubMed:14702039).CuratedAdd BLAST | 16 | |
Sequence conflicti | 403 – 473 | FLHSD…SLLDG → LCLLPQCLGGLPPTDTSVYS SASSDCCGCSMPVLCIMGHK PHVTVDT in BAC86509 (PubMed:14702039).CuratedAdd BLAST | 71 | |
Sequence conflicti | 409 | H → D in BAC86036 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 874 | W → S in BAB71033 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 892 – 896 | SLPKL → RLLPQ in BAC56931 (PubMed:14702039).Curated | 5 | |
Sequence conflicti | 1016 – 1027 | SIFSV…DQQIE → WERAHLSPVRPQ in BAB15733 (PubMed:14702039).CuratedAdd BLAST | 12 | |
Sequence conflicti | 1027 | E → EQ in CAH56483 (PubMed:17974005).Curated | 1 | |
Sequence conflicti | 1055 | W → R in BAB15733 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1055 | W → R in BAB71033 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1055 | W → R in BAC56931 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1055 | W → R in BAC86036 (PubMed:14702039).Curated | 1 | |
Sequence conflicti | 1055 | W → R in AAH25663 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 1055 | W → R in CAH56322 (PubMed:17974005).Curated | 1 | |
Sequence conflicti | 1055 | W → R in CAH56483 (PubMed:17974005).Curated | 1 | |
Sequence conflicti | 1140 | V → VV in CAH56483 (PubMed:17974005).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_061139 | 236 | R → H. Corresponds to variant dbSNP:rs12788Ensembl. | 1 | |
Natural variantiVAR_055696 | 286 | G → S. Corresponds to variant dbSNP:rs2298171Ensembl. | 1 | |
Natural variantiVAR_033060 | 323 | R → Q. Corresponds to variant dbSNP:rs11137410Ensembl. | 1 | |
Natural variantiVAR_033061 | 364 | Q → E. Corresponds to variant dbSNP:rs3750378Ensembl. | 1 | |
Natural variantiVAR_033062 | 368 | E → D. Corresponds to variant dbSNP:rs3750379Ensembl. | 1 | |
Natural variantiVAR_060409 | 387 | G → S. Corresponds to variant dbSNP:rs11791683Ensembl. | 1 | |
Natural variantiVAR_033063 | 803 | A → V. Corresponds to variant dbSNP:rs1891630Ensembl. | 1 | |
Natural variantiVAR_033064 | 824 | V → M. Corresponds to variant dbSNP:rs34938599Ensembl. | 1 | |
Natural variantiVAR_033065 | 908 | P → L1 PublicationCorresponds to variant dbSNP:rs3812499Ensembl. | 1 | |
Natural variantiVAR_033066 | 993 | L → M. Corresponds to variant dbSNP:rs35177111Ensembl. | 1 | |
Natural variantiVAR_055697 | 1050 | D → N1 PublicationCorresponds to variant dbSNP:rs4962237Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_026500 | 10 | Q → QADFCLGTALHSWGLWFTEE GSPSTM in isoform 2 and isoform 5. 1 Publication | 1 | |
Alternative sequenceiVSP_026501 | 384 – 433 | GGPGS…STVSQ → ARVLCLLPQCLGGLPPTDTS VYSSASSDCCGCSMPVLCIM GHKPHVTVDT in isoform 2. 1 PublicationAdd BLAST | 50 | |
Alternative sequenceiVSP_026502 | 434 – 1317 | Missing in isoform 2. 1 PublicationAdd BLAST | 884 | |
Alternative sequenceiVSP_026503 | 1191 – 1255 | EVGYQ…PAMVD → VP in isoform 3. 1 PublicationAdd BLAST | 65 | |
Alternative sequenceiVSP_026504 | 1256 – 1268 | DESDY…YEEEL → GEWRRKTKPWRRA in isoform 4. 1 PublicationAdd BLAST | 13 | |
Alternative sequenceiVSP_026505 | 1269 – 1317 | Missing in isoform 4. 1 PublicationAdd BLAST | 49 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK024443 mRNA Translation: BAB15733.1 AK055880 mRNA Translation: BAB71033.1 Different initiation. AK122590 mRNA Translation: BAC56931.1 AK125060 mRNA Translation: BAC86036.1 AK126267 mRNA Translation: BAC86509.1 AL365502 Genomic DNA No translation available. BC025663 mRNA Translation: AAH25663.1 AL832944 mRNA Translation: CAH56322.1 AL832856 mRNA Translation: CAH56483.1 |
CCDSi | CCDS48070.1 [Q6ZV29-5] CCDS7045.1 [Q6ZV29-1] |
RefSeqi | NP_001092007.2, NM_001098537.2 [Q6ZV29-5] NP_689499.4, NM_152286.4 [Q6ZV29-1] |
Genome annotation databases
Ensembli | ENST00000277531.8; ENSP00000277531.4; ENSG00000130653.16 ENST00000406427.6; ENSP00000384610.1; ENSG00000130653.16 [Q6ZV29-5] |
GeneIDi | 375775 |
KEGGi | hsa:375775 |
MANE-Selecti | ENST00000406427.6; ENSP00000384610.1; NM_001098537.3; NP_001092007.2 [Q6ZV29-5] |
UCSCi | uc004cnf.3, human [Q6ZV29-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK024443 mRNA Translation: BAB15733.1 AK055880 mRNA Translation: BAB71033.1 Different initiation. AK122590 mRNA Translation: BAC56931.1 AK125060 mRNA Translation: BAC86036.1 AK126267 mRNA Translation: BAC86509.1 AL365502 Genomic DNA No translation available. BC025663 mRNA Translation: AAH25663.1 AL832944 mRNA Translation: CAH56322.1 AL832856 mRNA Translation: CAH56483.1 |
CCDSi | CCDS48070.1 [Q6ZV29-5] CCDS7045.1 [Q6ZV29-1] |
RefSeqi | NP_001092007.2, NM_001098537.2 [Q6ZV29-5] NP_689499.4, NM_152286.4 [Q6ZV29-1] |
3D structure databases
AlphaFoldDBi | Q6ZV29 |
SMRi | Q6ZV29 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 131999, 6 interactors |
STRINGi | 9606.ENSP00000384610 |
PTM databases
iPTMneti | Q6ZV29 |
PhosphoSitePlusi | Q6ZV29 |
Genetic variation databases
BioMutai | PNPLA7 |
DMDMi | 296452996 |
Proteomic databases
EPDi | Q6ZV29 |
jPOSTi | Q6ZV29 |
MassIVEi | Q6ZV29 |
MaxQBi | Q6ZV29 |
PaxDbi | Q6ZV29 |
PeptideAtlasi | Q6ZV29 |
PRIDEi | Q6ZV29 |
ProteomicsDBi | 68378 [Q6ZV29-1] 68379 [Q6ZV29-2] 68380 [Q6ZV29-3] 68381 [Q6ZV29-4] 68382 [Q6ZV29-5] |
Protocols and materials databases
Antibodypediai | 2428, 9 antibodies from 7 providers |
DNASUi | 375775 |
Genome annotation databases
Ensembli | ENST00000277531.8; ENSP00000277531.4; ENSG00000130653.16 ENST00000406427.6; ENSP00000384610.1; ENSG00000130653.16 [Q6ZV29-5] |
GeneIDi | 375775 |
KEGGi | hsa:375775 |
MANE-Selecti | ENST00000406427.6; ENSP00000384610.1; NM_001098537.3; NP_001092007.2 [Q6ZV29-5] |
UCSCi | uc004cnf.3, human [Q6ZV29-1] |
Organism-specific databases
CTDi | 375775 |
DisGeNETi | 375775 |
GeneCardsi | PNPLA7 |
HGNCi | HGNC:24768, PNPLA7 |
HPAi | ENSG00000130653, Low tissue specificity |
MIMi | 612122, gene |
neXtProti | NX_Q6ZV29 |
OpenTargetsi | ENSG00000130653 |
PharmGKBi | PA134935962 |
VEuPathDBi | HostDB:ENSG00000130653 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG2968, Eukaryota |
GeneTreei | ENSGT00940000156763 |
HOGENOMi | CLU_000960_1_0_1 |
InParanoidi | Q6ZV29 |
OMAi | FTMNFTT |
OrthoDBi | 253518at2759 |
PhylomeDBi | Q6ZV29 |
TreeFami | TF300519 |
Enzyme and pathway databases
PathwayCommonsi | Q6ZV29 |
Reactomei | R-HSA-6814848, Glycerophospholipid catabolism |
Miscellaneous databases
BioGRID-ORCSi | 375775, 15 hits in 1074 CRISPR screens |
ChiTaRSi | PNPLA7, human |
GenomeRNAii | 375775 |
Pharosi | Q6ZV29, Tdark |
PROi | PR:Q6ZV29 |
RNActi | Q6ZV29, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000130653, Expressed in prostate gland and 133 other tissues |
ExpressionAtlasi | Q6ZV29, baseline and differential |
Genevisiblei | Q6ZV29, HS |
Family and domain databases
CDDi | cd00038, CAP_ED, 3 hits |
Gene3Di | 2.60.120.10, 3 hits |
InterProi | View protein in InterPro IPR016035, Acyl_Trfase/lysoPLipase IPR018490, cNMP-bd-like IPR000595, cNMP-bd_dom IPR002641, PNPLA_dom IPR014710, RmlC-like_jellyroll |
Pfami | View protein in Pfam PF00027, cNMP_binding, 3 hits PF01734, Patatin, 1 hit |
SMARTi | View protein in SMART SM00100, cNMP, 3 hits |
SUPFAMi | SSF51206, SSF51206, 3 hits SSF52151, SSF52151, 1 hit |
PROSITEi | View protein in PROSITE PS50042, CNMP_BINDING_3, 3 hits PS51635, PNPLA, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PLPL7_HUMAN | |
Accessioni | Q6ZV29Primary (citable) accession number: Q6ZV29 Secondary accession number(s): B5MDD3 Q9H7N5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 10, 2007 |
Last sequence update: | March 28, 2018 | |
Last modified: | May 25, 2022 | |
This is version 151 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families