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Protein

Spermatogenesis-associated protein 31D4

Gene

SPATA31D4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in spermatogenesis.By similarity

GO - Biological processi

Keywordsi

Biological processDifferentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Spermatogenesis-associated protein 31D4
Alternative name(s):
Protein FAM75D4
Gene namesi
Name:SPATA31D4
Synonyms:FAM75D4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000189357.8
HGNCiHGNC:38601 SPATA31D4
neXtProtiNX_Q6ZUB0

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000189357

Polymorphism and mutation databases

BioMutaiSPATA31D4
DMDMi74711931

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003322891 – 917Spermatogenesis-associated protein 31D4Add BLAST917

Proteomic databases

PeptideAtlasiQ6ZUB0
PRIDEiQ6ZUB0
ProteomicsDBi68325

PTM databases

iPTMnetiQ6ZUB0
PhosphoSitePlusiQ6ZUB0

Expressioni

Gene expression databases

BgeeiENSG00000189357 Expressed in 4 organ(s), highest expression level in right testis

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi187 – 247Pro-richAdd BLAST61
Compositional biasi542 – 592Pro-richAdd BLAST51

Sequence similaritiesi

Belongs to the SPATA31 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000063191
HOGENOMiHOG000155575
HOVERGENiHBG097810
InParanoidiQ6ZUB0
OMAiCFHKPQN

Family and domain databases

InterProiView protein in InterPro
IPR027970 DUF4599
PfamiView protein in Pfam
PF15371 DUF4599, 1 hit

Sequencei

Sequence statusi: Complete.

Q6ZUB0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENILCFLNS YTETGLSPDS HCLDIDLNFI CLSGLGLFIL YLFYMVLTLY
60 70 80 90 100
SSPTEKNNDT QKHQGRARRK RKSVTFKDRK SLQKEAEEER KLHSFLKSFG
110 120 130 140 150
PPVSCSPLGQ HHDTTLFRRL LCPDPVCRVC NRATADIQRL LSWESLKDAA
160 170 180 190 200
PSVSPLASSA SGAESSFTLA STPSATTPED LILSSRPKPS PPPPLILSPD
210 220 230 240 250
LITTLADLFS PSPLRDPLPP QPVSPLDSKF PIDHSPPQQL PFPLLPPHHI
260 270 280 290 300
ERVEPSLQPE ASLSLNTIFS FGSTLCQDIS QAVNRTDSCA RHHGPPTPSA
310 320 330 340 350
LPPEDCTVTQ SKSNLTVLKT FPEMLSLGGS GGSSTSAPTT KGIDHSCPAS
360 370 380 390 400
SEFSWWQPHA KDSFSSNFVP SDFMEELLTL HSSEASLGGH SVANIIQPVN
410 420 430 440 450
ISFLSHDIPA LLERQVKRRG DFLMWKENGK KPGSFPTQLR PNYQLNSSRN
460 470 480 490 500
MLTSTAVKHD LAESFPFWAS KGKLEWQHIH QQPPYSKCFE DHLEQKYVQL
510 520 530 540 550
FWGLPSLHSE SLHPTVFVQH GRSSMFVFFN GITNTSMSHE SPVLPPPQPL
560 570 580 590 600
FLPSTQPLPL PQTLPRGQSL HLTQVKSLAQ PQSPFPALPP SPLFLIRVCG
610 620 630 640 650
VCFHRPQNEA RSLMPSEINH LEWNVLQKVQ ESVWGLPSVV QKSQEDFCPP
660 670 680 690 700
APNPVLVRKS FKVHVPISII PGDFPLSSEV RKKLEQHIRK RLIQRRWGLP
710 720 730 740 750
RRIHESLSLL RPQNKISELS VSESIHGPLN ISLVEGQRCN VLKKSASSFP
760 770 780 790 800
RSFHERSSNM LSMENVGNYQ GCSQETAPKN HLLHDPETSS DEDLRSNSER
810 820 830 840 850
DLGTHMMHLS GNDSGVRLGQ KQLENALTVH LSKKFEEINE GRMPGTVHSS
860 870 880 890 900
WHSVKQTICL PEKSHSQIKH RNLAALVSED HGVDTSQEMS FLSSNKQKML
910
EAHIKSFHMK PILNLSI
Length:917
Mass (Da):102,306
Last modified:March 28, 2018 - v2
Checksum:iDA2FB7A5B7814392
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15G → V in BAC86316 (PubMed:14702039).1
Sequence conflicti690K → R in BAC86316 (PubMed:14702039).1
Sequence conflicti791D → E in BAC86316 (PubMed:14702039).1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK125847 mRNA Translation: BAC86316.1
AL158154 Genomic DNA No translation available.
CCDSiCCDS83379.1
RefSeqiNP_001138669.1, NM_001145197.1
UniGeneiHs.722630

Genome annotation databases

EnsembliENST00000419782; ENSP00000488251; ENSG00000189357
GeneIDi389761
KEGGihsa:389761

Similar proteinsi

Entry informationi

Entry nameiS31D4_HUMAN
AccessioniPrimary (citable) accession number: Q6ZUB0
Secondary accession number(s): A0A0J9YX51
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 29, 2008
Last sequence update: March 28, 2018
Last modified: September 12, 2018
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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