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Entry version 113 (31 Jul 2019)
Sequence version 2 (24 Jul 2007)
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Protein

Ubinuclein-2

Gene

UBN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Ubinuclein-2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UBN2
Synonyms:KIAA2030
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21931 UBN2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613841 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZU65

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000157741

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA164727415

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
UBN2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
156630841

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002957251 – 1347Ubinuclein-2Add BLAST1347

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei13PhosphoserineCombined sources1
Modified residuei243PhosphothreonineCombined sources1
Modified residuei250PhosphoserineCombined sources1
Modified residuei252PhosphothreonineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki272Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residuei311PhosphoserineCombined sources1
Modified residuei416PhosphoserineBy similarity1
Modified residuei419PhosphoserineBy similarity1
Modified residuei422PhosphoserineBy similarity1
Modified residuei584PhosphoserineCombined sources1
Modified residuei1068N6-acetyllysineBy similarity1
Modified residuei1123PhosphoserineCombined sources1
Modified residuei1148N6-acetyllysineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6ZU65

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6ZU65

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZU65

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZU65

PeptideAtlas

More...
PeptideAtlasi
Q6ZU65

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZU65

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68313 [Q6ZU65-1]
68314 [Q6ZU65-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZU65

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZU65

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in several cell lines tested, including primary and transformed cell lines.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000157741 Expressed in 207 organ(s), highest expression level in pituitary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZU65 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZU65 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA019743
HPA020122
HPA020124

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129009, 16 interactors

Database of interacting proteins

More...
DIPi
DIP-47312N

Protein interaction database and analysis system

More...
IntActi
Q6ZU65, 8 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000418648

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZU65

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi23 – 123Pro-richAdd BLAST101
Compositional biasi262 – 345Lys-richAdd BLAST84
Compositional biasi884 – 1224Ser-richAdd BLAST341

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ubinuclein family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4786 Eukaryota
ENOG4110DA0 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155858

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000154754

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZU65

KEGG Orthology (KO)

More...
KOi
K17492

Identification of Orthologs from Complete Genome Data

More...
OMAi
FNDEHQE

Database of Orthologous Groups

More...
OrthoDBi
469344at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZU65

TreeFam database of animal gene trees

More...
TreeFami
TF326088

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014840 HRD
IPR026943 Ubinuclein-2
IPR026947 UBN_middle_dom

The PANTHER Classification System

More...
PANTHERi
PTHR21669:SF10 PTHR21669:SF10, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08729 HUN, 1 hit
PF14075 UBN_AB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6ZU65-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEPRRVAFI SLSPVRRREA EYPGPEREPE YPREPPRLEP QPYREPARAE
60 70 80 90 100
PPAPREPAPR SDAQPPSREK PLPQREVSRA EPPMSLQREP PRPEPPPPFP
110 120 130 140 150
PLPLQPPPPR ESASRAEQPP RPPRETVRLE LVLKDPTDES CVEFSYPELL
160 170 180 190 200
LCGEQRKKLI HTEDPFNDEH QERQEVEMLA KKFEMKYGGK PRKHRKDRLQ
210 220 230 240 250
DLIDIGFGYD ETDPFIDNSE AYDELVPASL TTKYGGFYIN TGTLQFRQAS
260 270 280 290 300
DTEEDDITDN QKHKPPKVPK IKEDDIEMKK RKRKEEGEKE KKPRKKVPKQ
310 320 330 340 350
LGVVALNSHK SEKKKKRYKD SLSLAAMIRK FQKEKDALKK ESNPKVPVTL
360 370 380 390 400
STPSLNKPPC AAAALGNDVP DLNLSSGDPD LPIFVSTNEH ELFQEAENAL
410 420 430 440 450
EMLDDFDFDR LLDAASDGSP LSESGGENGT TTQPTYTSQV MPKVVPTLPE
460 470 480 490 500
GLPVLLEKRI EDLRVAAKLF DEEGRKKFFT QDMNNILLDI ELQLQELGPV
510 520 530 540 550
IRSGVYSHLE AFVPCNKETL VKRLKKLHLN VQDDRLREPL QKLKLAVSNV
560 570 580 590 600
MPEQLFKYQE DCQARSQAKC AKLQTDEERE KNGSEEDDDE KPGKRVIGPR
610 620 630 640 650
KKFHWDDTIR TLLCNLVEIK LGCYELEPNK SQSAEDYLKS FMETEVKPLW
660 670 680 690 700
PKGWMQARML FKESRSVHNH LTSAPAKKKV IPAPKPKVKE VMVKTLPLHS
710 720 730 740 750
FPTMLKECSP KKDQKTPTSL VASVSGPPTS SSTAAIAAAS SSSAPAQETI
760 770 780 790 800
CLDDSLDEDL SFHSPSLDLV SEALAVINNG NKGPPVGSRI SMPTTKPRPG
810 820 830 840 850
LREEKLASIM SKLPLATPKK LDSTQTTHSS SLIAGHTGPV PKKPQDLAHT
860 870 880 890 900
GISSGLIAGS SIQNPKVSLE PLPARLLQQG LQRSSQIHTS SSSQTHVSSS
910 920 930 940 950
SQAQIAASSH ALGTSEAQDA SSLTQVTKVH QHSAVQQNYV SPLQATISKS
960 970 980 990 1000
QTNPVVKLSN NPQLSCSSSL IKTSDKPLMY RLPLSTPSPG NGSQGSHPLV
1010 1020 1030 1040 1050
SRTVPSTTTS SNYLAKAMVS QISTQGFKSP FSMAASPKLA ASPKPATSPK
1060 1070 1080 1090 1100
PLPSPKPSAS PKPSLSAKPS VSTKLISKSN PTPKPTVSPS SSSPNALVAQ
1110 1120 1130 1140 1150
GSHSSTNSPV HKQPSGMNIS RQSPTLNLLP SSRTSGLPPT KNLQAPSKLT
1160 1170 1180 1190 1200
NSSSTGTVGK NSLSGIAMNV PASRGSNLNS SGANRTSLSG GTGSGTQGAT
1210 1220 1230 1240 1250
KPLSTPHRPS TASGSSVVTA SVQSTAGASL LANASPLTLM TSPLSVTNQN
1260 1270 1280 1290 1300
VTPFGMLGGL VPVTMPFQFP LEIFGFGTDT AGVTTTSGST SAAFHHSLTQ
1310 1320 1330 1340
NLLKGLQPGG AQHAATLSHS PLPAHLQQAF HDGGQSKGDT KLPRKSQ
Length:1,347
Mass (Da):146,089
Last modified:July 24, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6B52672B860B18B5
GO
Isoform 2 (identifier: Q6ZU65-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     958-970: LSNNPQLSCSSSL → GPCLRDVSEQFGP
     971-1347: Missing.

Note: No experimental confirmation available.
Show »
Length:970
Mass (Da):108,070
Checksum:i20E88FEA63650CE2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C4P8H7C4P8_HUMAN
Ubinuclein-2
UBN2
444Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9J6Y5C9J6Y5_HUMAN
Ubinuclein-2
UBN2
137Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC05362 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence EAL24038 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0333471308P → A. Corresponds to variant dbSNP:rs17160850Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_027021958 – 970LSNNP…CSSSL → GPCLRDVSEQFGP in isoform 2. 1 PublicationAdd BLAST13
Alternative sequenceiVSP_027022971 – 1347Missing in isoform 2. 1 PublicationAdd BLAST377

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC009220 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24038.1 Sequence problems.
AK098644 mRNA Translation: BAC05362.1 Different initiation.
AK125956 mRNA Translation: BAC86361.1
BC065034 mRNA Translation: AAH65034.1
BC108249 mRNA Translation: AAI08250.1
AB107352 mRNA Translation: BAC67657.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS43655.2 [Q6ZU65-1]

NCBI Reference Sequences

More...
RefSeqi
NP_775840.3, NM_173569.3 [Q6ZU65-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000473989; ENSP00000418648; ENSG00000157741 [Q6ZU65-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
254048

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:254048

UCSC genome browser

More...
UCSCi
uc011kqr.2 human [Q6ZU65-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC009220 Genomic DNA No translation available.
CH236950 Genomic DNA Translation: EAL24038.1 Sequence problems.
AK098644 mRNA Translation: BAC05362.1 Different initiation.
AK125956 mRNA Translation: BAC86361.1
BC065034 mRNA Translation: AAH65034.1
BC108249 mRNA Translation: AAI08250.1
AB107352 mRNA Translation: BAC67657.1
CCDSiCCDS43655.2 [Q6ZU65-1]
RefSeqiNP_775840.3, NM_173569.3 [Q6ZU65-1]

3D structure databases

SMRiQ6ZU65
ModBaseiSearch...

Protein-protein interaction databases

BioGridi129009, 16 interactors
DIPiDIP-47312N
IntActiQ6ZU65, 8 interactors
STRINGi9606.ENSP00000418648

PTM databases

iPTMnetiQ6ZU65
PhosphoSitePlusiQ6ZU65

Polymorphism and mutation databases

BioMutaiUBN2
DMDMi156630841

Proteomic databases

EPDiQ6ZU65
jPOSTiQ6ZU65
MaxQBiQ6ZU65
PaxDbiQ6ZU65
PeptideAtlasiQ6ZU65
PRIDEiQ6ZU65
ProteomicsDBi68313 [Q6ZU65-1]
68314 [Q6ZU65-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000473989; ENSP00000418648; ENSG00000157741 [Q6ZU65-1]
GeneIDi254048
KEGGihsa:254048
UCSCiuc011kqr.2 human [Q6ZU65-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
254048

GeneCards: human genes, protein and diseases

More...
GeneCardsi
UBN2
HGNCiHGNC:21931 UBN2
HPAiHPA019743
HPA020122
HPA020124
MIMi613841 gene
neXtProtiNX_Q6ZU65
OpenTargetsiENSG00000157741
PharmGKBiPA164727415

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4786 Eukaryota
ENOG4110DA0 LUCA
GeneTreeiENSGT00940000155858
HOGENOMiHOG000154754
InParanoidiQ6ZU65
KOiK17492
OMAiFNDEHQE
OrthoDBi469344at2759
PhylomeDBiQ6ZU65
TreeFamiTF326088

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
UBN2 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
254048

Protein Ontology

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PROi
PR:Q6ZU65

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000157741 Expressed in 207 organ(s), highest expression level in pituitary gland
ExpressionAtlasiQ6ZU65 baseline and differential
GenevisibleiQ6ZU65 HS

Family and domain databases

InterProiView protein in InterPro
IPR014840 HRD
IPR026943 Ubinuclein-2
IPR026947 UBN_middle_dom
PANTHERiPTHR21669:SF10 PTHR21669:SF10, 1 hit
PfamiView protein in Pfam
PF08729 HUN, 1 hit
PF14075 UBN_AB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUBN2_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZU65
Secondary accession number(s): A4D1S2
, Q2YDY4, Q6P1K0, Q86XN9, Q8N7D1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: July 24, 2007
Last modified: July 31, 2019
This is version 113 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
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