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Entry version 124 (08 May 2019)
Sequence version 2 (29 May 2007)
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Protein

TBC1 domain family member 9

Gene

TBC1D9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May act as a GTPase-activating protein for Rab family protein(s).

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection describes interesting single amino acid sites on the sequence that are not defined in any other subsection. This subsection can be displayed in different sections (‘Function’, ‘PTM / Processing’, ‘Pathology and Biotech’) according to its content.<p><a href='/help/site' target='_top'>More...</a></p>Sitei562Arginine fingerBy similarity1
Sitei601Glutamine fingerBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TBC1 domain family member 9
Alternative name(s):
TBC1 domain family member 9A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TBC1D9
Synonyms:KIAA0882, TBC1D9A
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:21710 TBC1D9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
618035 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZT07

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
23158

Open Targets

More...
OpenTargetsi
ENSG00000109436

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA128394607

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TBC1D9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
148887054

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002884991 – 1266TBC1 domain family member 9Add BLAST1266

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6ZT07

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6ZT07

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZT07

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZT07

PeptideAtlas

More...
PeptideAtlasi
Q6ZT07

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZT07

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68251

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZT07

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZT07

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000109436 Expressed in 231 organ(s), highest expression level in cerebellum

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZT07 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000262
HPA006317
HPA006503

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116771, 23 interactors

Protein interaction database and analysis system

More...
IntActi
Q6ZT07, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000411197

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZT07

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini146 – 213GRAM 1Add BLAST68
Domaini293 – 361GRAM 2Add BLAST69
Domaini515 – 702Rab-GAP TBCPROSITE-ProRule annotationAdd BLAST188
Domaini886 – 921EF-handPROSITE-ProRule annotationAdd BLAST36

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The arginine and glutamine fingers are critical for the GTPase-activating mechanism, they pull out Rab's 'switch 2' glutamine and insert in Rab's active site.By similarity

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4347 Eukaryota
COG5210 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157878

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000276905

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZT07

KEGG Orthology (KO)

More...
KOi
K19951

Identification of Orthologs from Complete Genome Data

More...
OMAi
WLEHNLL

Database of Orthologous Groups

More...
OrthoDBi
450360at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZT07

TreeFam database of animal gene trees

More...
TreeFami
TF313145

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13351 PH-GRAM1_TCB1D9_TCB1D9B, 1 hit
cd13354 PH-GRAM2_TCB1D9_TCB1D9B, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR036014 TCB1D9/TCB1D9B_PH-GRAM1
IPR036017 TCB1D9/TCB1D9B_PH-GRAM2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02893 GRAM, 2 hits
PF00566 RabGAP-TBC, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00568 GRAM, 2 hits
SM00164 TBC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47473 SSF47473, 1 hit
SSF47923 SSF47923, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50222 EF_HAND_2, 1 hit
PS50086 TBC_RABGAP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6ZT07-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWVNPEEVLL ANALWITERA NPYFILQRRK GHAGDGGGGG GLAGLLVGTL
60 70 80 90 100
DVVLDSSARV APYRILYQTP DSLVYWTIAC GGSRKEITEH WEWLEQNLLQ
110 120 130 140 150
TLSIFENEND ITTFVRGKIQ GIIAEYNKIN DVKEDDDTEK FKEAIVKFHR
160 170 180 190 200
LFGMPEEEKL VNYYSCSYWK GKVPRQGWMY LSINHLCFYS FLMGREAKLV
210 220 230 240 250
IRWVDITQLE KNATLLLPDV IKVSTRSSEH FFSVFLNINE TFKLMEQLAN
260 270 280 290 300
IAMRQLLDNE GFEQDRSLPK LKRKSPKKVS ALKRDLDARA KSERYRALFR
310 320 330 340 350
LPKDEKLDGH TDCTLWTPFN KMHILGQMFV STNYICFTSK EENLCSLIIP
360 370 380 390 400
LREVTIVEKA DSSSVLPSPL SISTRNRMTF LFANLKDRDF LVQRISDFLQ
410 420 430 440 450
QTTSKIYSDK EFAGSYNSSD DEVYSRPSSL VSSSPQRSTS SDADGERQFN
460 470 480 490 500
LNGNSVPTAT QTLMTMYRRR SPEEFNPKLA KEFLKEQAWK IHFAEYGQGI
510 520 530 540 550
CMYRTEKTRE LVLKGIPESM RGELWLLLSG AINEKATHPG YYEDLVEKSM
560 570 580 590 600
GKYNLATEEI ERDLHRSLPE HPAFQNEMGI AALRRVLTAY AFRNPNIGYC
610 620 630 640 650
QAMNIVTSVL LLYAKEEEAF WLLVALCERM LPDYYNTRVV GALVDQGVFE
660 670 680 690 700
ELARDYVPQL YDCMQDLGVI STISLSWFLT LFLSVMPFES AVVVVDCFFY
710 720 730 740 750
EGIKVIFQLA LAVLDANVDK LLNCKDDGEA MTVLGRYLDS VTNKDSTLPP
760 770 780 790 800
IPHLHSLLSD DVEPYPEVDI FRLIRTSYEK FGTIRADLIE QMRFKQRLKV
810 820 830 840 850
IQTLEDTTKR NVVRTIVTET SFTIDELEEL YALFKAEHLT SCYWGGSSNA
860 870 880 890 900
LDRHDPSLPY LEQYRIDFEQ FKGMFALLFP WACGTHSDVL ASRLFQLLDE
910 920 930 940 950
NGDSLINFRE FVSGLSAACH GDLTEKLKLL YKMHVLPEPS SDQDEPDSAF
960 970 980 990 1000
EATQYFFEDI TPECTHVVGL DSRSKQGADD GFVTVSLKPD KGKRANSQEN
1010 1020 1030 1040 1050
RNYLRLWTPE NKSKSKNAKD LPKLNQGQFI ELCKTMYNMF SEDPNEQELY
1060 1070 1080 1090 1100
HATAAVTSLL LEIGEVGKLF VAQPAKEGGS GGSGPSCHQG IPGVLFPKKG
1110 1120 1130 1140 1150
PGQPYVVESV EPLPASLAPD SEEHSLGGQM EDIKLEDSSP RDNGACSSML
1160 1170 1180 1190 1200
ISDDDTKDDS SMSSYSVLSA GSHEEDKLHC EDIGEDTVLV RSGQGTAALP
1210 1220 1230 1240 1250
RSTSLDRDWA ITFEQFLASL LTEPALVKYF DKPVCMMARI TSAKNIRMMG
1260
KPLTSASDYE ISAMSG
Length:1,266
Mass (Da):143,229
Last modified:May 29, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4A300EE192685088
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAA74905 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC86789 differs from that shown. Aberrant splicing.Curated
The sequence BAC86789 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti1204S → G in BAC86789 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0525397E → K. Corresponds to variant dbSNP:rs13108827Ensembl.1
Natural variantiVAR_052540779E → K. Corresponds to variant dbSNP:rs13118702Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB449892 mRNA Translation: BAH16635.1
AB020689 mRNA Translation: BAA74905.2 Different initiation.
CH471056 Genomic DNA Translation: EAX05092.1
CH471056 Genomic DNA Translation: EAX05094.1
BC146758 mRNA Translation: AAI46759.1
AK127020 mRNA Translation: BAC86789.1 Sequence problems.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS47136.1

NCBI Reference Sequences

More...
RefSeqi
NP_055945.2, NM_015130.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000442267; ENSP00000411197; ENSG00000109436

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23158

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:23158

UCSC genome browser

More...
UCSCi
uc010ioj.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB449892 mRNA Translation: BAH16635.1
AB020689 mRNA Translation: BAA74905.2 Different initiation.
CH471056 Genomic DNA Translation: EAX05092.1
CH471056 Genomic DNA Translation: EAX05094.1
BC146758 mRNA Translation: AAI46759.1
AK127020 mRNA Translation: BAC86789.1 Sequence problems.
CCDSiCCDS47136.1
RefSeqiNP_055945.2, NM_015130.2

3D structure databases

SMRiQ6ZT07
ModBaseiSearch...

Protein-protein interaction databases

BioGridi116771, 23 interactors
IntActiQ6ZT07, 7 interactors
STRINGi9606.ENSP00000411197

PTM databases

iPTMnetiQ6ZT07
PhosphoSitePlusiQ6ZT07

Polymorphism and mutation databases

BioMutaiTBC1D9
DMDMi148887054

Proteomic databases

EPDiQ6ZT07
jPOSTiQ6ZT07
MaxQBiQ6ZT07
PaxDbiQ6ZT07
PeptideAtlasiQ6ZT07
PRIDEiQ6ZT07
ProteomicsDBi68251

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000442267; ENSP00000411197; ENSG00000109436
GeneIDi23158
KEGGihsa:23158
UCSCiuc010ioj.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23158
DisGeNETi23158

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TBC1D9
HGNCiHGNC:21710 TBC1D9
HPAiHPA000262
HPA006317
HPA006503
MIMi618035 gene
neXtProtiNX_Q6ZT07
OpenTargetsiENSG00000109436
PharmGKBiPA128394607

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG4347 Eukaryota
COG5210 LUCA
GeneTreeiENSGT00940000157878
HOGENOMiHOG000276905
InParanoidiQ6ZT07
KOiK19951
OMAiWLEHNLL
OrthoDBi450360at2759
PhylomeDBiQ6ZT07
TreeFamiTF313145

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TBC1D9 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TBC1D9

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
23158

Protein Ontology

More...
PROi
PR:Q6ZT07

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000109436 Expressed in 231 organ(s), highest expression level in cerebellum
GenevisibleiQ6ZT07 HS

Family and domain databases

CDDicd13351 PH-GRAM1_TCB1D9_TCB1D9B, 1 hit
cd13354 PH-GRAM2_TCB1D9_TCB1D9B, 1 hit
Gene3Di2.30.29.30, 2 hits
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR004182 GRAM
IPR011993 PH-like_dom_sf
IPR000195 Rab-GTPase-TBC_dom
IPR035969 Rab-GTPase_TBC_sf
IPR036014 TCB1D9/TCB1D9B_PH-GRAM1
IPR036017 TCB1D9/TCB1D9B_PH-GRAM2
PfamiView protein in Pfam
PF02893 GRAM, 2 hits
PF00566 RabGAP-TBC, 1 hit
SMARTiView protein in SMART
SM00568 GRAM, 2 hits
SM00164 TBC, 1 hit
SUPFAMiSSF47473 SSF47473, 1 hit
SSF47923 SSF47923, 2 hits
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
PS50086 TBC_RABGAP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBCD9_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZT07
Secondary accession number(s): A6H8U8, D3DNZ1, O94958
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: May 29, 2007
Last modified: May 8, 2019
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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