UniProtKB - Q6ZSJ8 (CA122_HUMAN)
Protein
Uncharacterized protein C1orf122
Gene
C1orf122
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized protein C1orf122Alternative name(s): Protein ALAESM |
Gene namesi | Name:C1orf122 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:24789, C1orf122 |
neXtProti | NX_Q6ZSJ8 |
VEuPathDBi | HostDB:ENSG00000197982.13 |
Pathology & Biotechi
Organism-specific databases
OpenTargetsi | ENSG00000197982 |
PharmGKBi | PA142672440 |
Miscellaneous databases
Pharosi | Q6ZSJ8, Tdark |
Genetic variation databases
BioMutai | C1orf122 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000254193 | 1 – 110 | Uncharacterized protein C1orf122Add BLAST | 110 |
Proteomic databases
EPDi | Q6ZSJ8 |
jPOSTi | Q6ZSJ8 |
MassIVEi | Q6ZSJ8 |
MaxQBi | Q6ZSJ8 |
PaxDbi | Q6ZSJ8 |
PeptideAtlasi | Q6ZSJ8 |
PRIDEi | Q6ZSJ8 |
ProteomicsDBi | 22883 68221 [Q6ZSJ8-1] |
TopDownProteomicsi | Q6ZSJ8-1 [Q6ZSJ8-1] |
PTM databases
iPTMneti | Q6ZSJ8 |
PhosphoSitePlusi | Q6ZSJ8 |
Expressioni
Gene expression databases
Bgeei | ENSG00000197982, Expressed in substantia nigra and 218 other tissues |
Genevisiblei | Q6ZSJ8, HS |
Organism-specific databases
HPAi | ENSG00000197982, Low tissue specificity |
Interactioni
Protein-protein interaction databases
BioGRIDi | 126077, 11 interactors |
IntActi | Q6ZSJ8, 10 interactors |
STRINGi | 9606.ENSP00000362133 |
Miscellaneous databases
RNActi | Q6ZSJ8, protein |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 36 – 68 | Sequence analysisAdd BLAST | 33 |
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | ENOG502TDYG, Eukaryota |
GeneTreei | ENSGT00570000079623 |
HOGENOMi | CLU_3175232_0_0_1 |
InParanoidi | Q6ZSJ8 |
OMAi | AREARPH |
OrthoDBi | 1560404at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR031714, DUF4726 |
PANTHERi | PTHR41401, PTHR41401, 1 hit |
Pfami | View protein in Pfam PF15855, DUF4726, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: Q6ZSJ8-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MEWGPGSDWS RGEAAGVDRG KAGLGLGGRP PPQPPREERA QQLLDAVEQR
60 70 80 90 100
QRQLLDTIAA CEEMLRQLGR RRPEPAGGGN VSAKPGAPPQ PAVSARGGFP
110
KDAGDGAAEP
Sequence cautioni
The sequence AAH57819 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
The sequence BAC86950 differs from that shown. Reason: Erroneous translation. Wrong choice of CDS.Curated
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_046648 | 1 – 63 | Missing in isoform 2. CuratedAdd BLAST | 63 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK127381 mRNA Translation: BAC86950.1 Sequence problems. AY517499 mRNA Translation: AAS76640.1 AL929472 Genomic DNA No translation available. BC057819 mRNA Translation: AAH57819.1 Sequence problems. |
CCDSi | CCDS427.2 [Q6ZSJ8-1] CCDS44112.1 [Q6ZSJ8-2] |
RefSeqi | NP_001136198.1, NM_001142726.1 [Q6ZSJ8-2] NP_940848.2, NM_198446.2 [Q6ZSJ8-1] |
Genome annotation databases
Ensembli | ENST00000373042; ENSP00000362133; ENSG00000197982 [Q6ZSJ8-1] ENST00000373043; ENSP00000362134; ENSG00000197982 [Q6ZSJ8-2] ENST00000468084; ENSP00000434520; ENSG00000197982 [Q6ZSJ8-2] |
GeneIDi | 127687 |
KEGGi | hsa:127687 |
UCSCi | uc001ccd.3, human [Q6ZSJ8-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK127381 mRNA Translation: BAC86950.1 Sequence problems. AY517499 mRNA Translation: AAS76640.1 AL929472 Genomic DNA No translation available. BC057819 mRNA Translation: AAH57819.1 Sequence problems. |
CCDSi | CCDS427.2 [Q6ZSJ8-1] CCDS44112.1 [Q6ZSJ8-2] |
RefSeqi | NP_001136198.1, NM_001142726.1 [Q6ZSJ8-2] NP_940848.2, NM_198446.2 [Q6ZSJ8-1] |
3D structure databases
SMRi | Q6ZSJ8 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 126077, 11 interactors |
IntActi | Q6ZSJ8, 10 interactors |
STRINGi | 9606.ENSP00000362133 |
PTM databases
iPTMneti | Q6ZSJ8 |
PhosphoSitePlusi | Q6ZSJ8 |
Genetic variation databases
BioMutai | C1orf122 |
Proteomic databases
EPDi | Q6ZSJ8 |
jPOSTi | Q6ZSJ8 |
MassIVEi | Q6ZSJ8 |
MaxQBi | Q6ZSJ8 |
PaxDbi | Q6ZSJ8 |
PeptideAtlasi | Q6ZSJ8 |
PRIDEi | Q6ZSJ8 |
ProteomicsDBi | 22883 68221 [Q6ZSJ8-1] |
TopDownProteomicsi | Q6ZSJ8-1 [Q6ZSJ8-1] |
Protocols and materials databases
Antibodypediai | 54370, 51 antibodies |
Genome annotation databases
Ensembli | ENST00000373042; ENSP00000362133; ENSG00000197982 [Q6ZSJ8-1] ENST00000373043; ENSP00000362134; ENSG00000197982 [Q6ZSJ8-2] ENST00000468084; ENSP00000434520; ENSG00000197982 [Q6ZSJ8-2] |
GeneIDi | 127687 |
KEGGi | hsa:127687 |
UCSCi | uc001ccd.3, human [Q6ZSJ8-1] |
Organism-specific databases
CTDi | 127687 |
GeneCardsi | C1orf122 |
HGNCi | HGNC:24789, C1orf122 |
HPAi | ENSG00000197982, Low tissue specificity |
neXtProti | NX_Q6ZSJ8 |
OpenTargetsi | ENSG00000197982 |
PharmGKBi | PA142672440 |
VEuPathDBi | HostDB:ENSG00000197982.13 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502TDYG, Eukaryota |
GeneTreei | ENSGT00570000079623 |
HOGENOMi | CLU_3175232_0_0_1 |
InParanoidi | Q6ZSJ8 |
OMAi | AREARPH |
OrthoDBi | 1560404at2759 |
Enzyme and pathway databases
PathwayCommonsi | Q6ZSJ8 |
Miscellaneous databases
BioGRID-ORCSi | 127687, 5 hits in 858 CRISPR screens |
ChiTaRSi | C1orf122, human |
GenomeRNAii | 127687 |
Pharosi | Q6ZSJ8, Tdark |
PROi | PR:Q6ZSJ8 |
RNActi | Q6ZSJ8, protein |
Gene expression databases
Bgeei | ENSG00000197982, Expressed in substantia nigra and 218 other tissues |
Genevisiblei | Q6ZSJ8, HS |
Family and domain databases
InterProi | View protein in InterPro IPR031714, DUF4726 |
PANTHERi | PTHR41401, PTHR41401, 1 hit |
Pfami | View protein in Pfam PF15855, DUF4726, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CA122_HUMAN | |
Accessioni | Q6ZSJ8Primary (citable) accession number: Q6ZSJ8 Secondary accession number(s): A2RQF4, E9PQ13, Q56A71 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | September 22, 2009 | |
Last modified: | February 10, 2021 | |
This is version 110 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 1
Human chromosome 1: entries, gene names and cross-references to MIM