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Entry version 131 (31 Jul 2019)
Sequence version 2 (28 Jun 2011)
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Protein

Putative glycerol kinase 5

Gene

GK5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: glycerol degradation via glycerol kinase pathway

This protein is involved in step 1 of the subpathway that synthesizes sn-glycerol 3-phosphate from glycerol.
Proteins known to be involved in this subpathway in this organism are:
  1. Glycerol kinase 3 (GK3P), Glycerol kinase (GK), Glycerol kinase 2 (GK2), Putative glycerol kinase 5 (GK5)
This subpathway is part of the pathway glycerol degradation via glycerol kinase pathway, which is itself part of Polyol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes sn-glycerol 3-phosphate from glycerol, the pathway glycerol degradation via glycerol kinase pathway and in Polyol metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei28SubstrateBy similarity1
Binding sitei98SubstrateBy similarity1
Binding sitei275SubstrateBy similarity1
Binding sitei297ATPBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi439 – 444ATPBy similarity6

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Transferase
Biological processGlycerol metabolism
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00618;UER00672

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative glycerol kinase 5 (EC:2.7.1.30)
Short name:
GK 5
Short name:
Glycerokinase 5
Alternative name(s):
ATP:glycerol 3-phosphotransferase 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GK5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28635 GK5

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZS86

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
256356

Open Targets

More...
OpenTargetsi
ENSG00000175066

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162389723

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GK5

Domain mapping of disease mutations (DMDM)

More...
DMDMi
338817880

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003237541 – 529Putative glycerol kinase 5Add BLAST529

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6ZS86

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZS86

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZS86

PeptideAtlas

More...
PeptideAtlasi
Q6ZS86

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZS86

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68203 [Q6ZS86-1]
68204 [Q6ZS86-2]
68205 [Q6ZS86-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZS86

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZS86

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000175066 Expressed in 180 organ(s), highest expression level in C1 segment of cervical spinal cord

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZS86 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZS86 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA042606
HPA057998

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
129160, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000418001

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZS86

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FGGY kinase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2517 Eukaryota
COG0554 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182753

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000222134

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZS86

KEGG Orthology (KO)

More...
KOi
K19583

Identification of Orthologs from Complete Genome Data

More...
OMAi
GKPFHNF

Database of Orthologous Groups

More...
OrthoDBi
519426at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZS86

TreeFam database of animal gene trees

More...
TreeFami
TF321504

Family and domain databases

Conserved Domains Database

More...
CDDi
cd07793 FGGY_GK5_metazoa, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018483 Carb_kinase_FGGY_CS
IPR018484 Carb_kinase_FGGY_N
IPR037444 GK5_FGGY

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF000538 GlpK, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00445 FGGY_KINASES_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6ZS86-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSGLLTDPEQ RAQEPRYPGF VLGLDVGSSV IRCHVYDRAA RVCGSSVQKV
60 70 80 90 100
ENLYPQIGWV EIDPDVLWIQ FVAVIKEAVK AAGIQMNQIV GLGISTQRAT
110 120 130 140 150
FITWNKKTGN HFHNFISWQD LRAVELVKSW NNSLLMKIFH SSCRVLHFFT
160 170 180 190 200
RSKRLFTASL FTFTTQQTSL RLVWILQNLT EVQKAVEEEN CCFGTIDTWL
210 220 230 240 250
LYKLTKGSVY ATDFSNASTT GLFDPYKMCW SGMITSLISI PLSLLPPVRD
260 270 280 290 300
TSHNFGSVDE EIFGVPIPIV ALVADQQSAM FGECCFQTGD VKLTMGTGTF
310 320 330 340 350
LDINTGNSLQ QTTGGFYPLI GWKIGQEVVC LAESNAGDTG TAIKWAQQLD
360 370 380 390 400
LFTDAAETEK MAKSLEDSEG VCFVPSFSGL QAPLNDPWAC ASFMGLKPST
410 420 430 440 450
SKYHLVRAIL ESIAFRNKQL YEMMKKEIHI PVRKIRADGG VCKNGFVMQM
460 470 480 490 500
TSDLINENID RPADIDMSCL GAASLAGLAV GFWTDKEELK KLRQSEVVFK
510 520
PQKKCQEYEM SLENWAKAVK RSMNWYNKT
Length:529
Mass (Da):59,156
Last modified:June 28, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9ED7CB1DA4D9417D
GO
Isoform 2 (identifier: Q6ZS86-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     273-301: VADQQSAMFGECCFQTGDVKLTMGTGTFL → LKVPGYDQNICYIFGKGTIEPVFYHGSTL
     302-529: Missing.

Show »
Length:301
Mass (Da):33,916
Checksum:i12D1049F6270FF17
GO
Isoform 3 (identifier: Q6ZS86-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-279: Missing.

Show »
Length:250
Mass (Da):27,801
Checksum:iD8A63C70DCD93D7D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C5R4H7C5R4_HUMAN
Putative glycerol kinase 5
GK5
172Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F8WBF0F8WBF0_HUMAN
Putative glycerol kinase 5
GK5
153Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C4F2H7C4F2_HUMAN
Putative glycerol kinase 5
GK5
17Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti339T → I in BAC87068 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0321211 – 279Missing in isoform 3. 1 PublicationAdd BLAST279
Alternative sequenceiVSP_032122273 – 301VADQQ…TGTFL → LKVPGYDQNICYIFGKGTIE PVFYHGSTL in isoform 2. 2 PublicationsAdd BLAST29
Alternative sequenceiVSP_032123302 – 529Missing in isoform 2. 2 PublicationsAdd BLAST228

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK090901 mRNA Translation: BAC03542.1
AK127641 mRNA Translation: BAC87068.1
AK313792 mRNA Translation: BAG36529.1
AC108679 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW78974.1
CH471052 Genomic DNA Translation: EAW78975.1
BC032470 mRNA Translation: AAH32470.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS33871.1 [Q6ZS86-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001034636.1, NM_001039547.2 [Q6ZS86-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000392993; ENSP00000418001; ENSG00000175066 [Q6ZS86-1]
ENST00000480757; ENSP00000419031; ENSG00000175066 [Q6ZS86-2]
ENST00000492097; ENSP00000420312; ENSG00000175066 [Q6ZS86-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
256356

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:256356

UCSC genome browser

More...
UCSCi
uc003euq.2 human [Q6ZS86-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK090901 mRNA Translation: BAC03542.1
AK127641 mRNA Translation: BAC87068.1
AK313792 mRNA Translation: BAG36529.1
AC108679 Genomic DNA No translation available.
CH471052 Genomic DNA Translation: EAW78974.1
CH471052 Genomic DNA Translation: EAW78975.1
BC032470 mRNA Translation: AAH32470.1
CCDSiCCDS33871.1 [Q6ZS86-1]
RefSeqiNP_001034636.1, NM_001039547.2 [Q6ZS86-1]

3D structure databases

SMRiQ6ZS86
ModBaseiSearch...

Protein-protein interaction databases

BioGridi129160, 1 interactor
STRINGi9606.ENSP00000418001

PTM databases

iPTMnetiQ6ZS86
PhosphoSitePlusiQ6ZS86

Polymorphism and mutation databases

BioMutaiGK5
DMDMi338817880

Proteomic databases

EPDiQ6ZS86
MaxQBiQ6ZS86
PaxDbiQ6ZS86
PeptideAtlasiQ6ZS86
PRIDEiQ6ZS86
ProteomicsDBi68203 [Q6ZS86-1]
68204 [Q6ZS86-2]
68205 [Q6ZS86-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
256356
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000392993; ENSP00000418001; ENSG00000175066 [Q6ZS86-1]
ENST00000480757; ENSP00000419031; ENSG00000175066 [Q6ZS86-2]
ENST00000492097; ENSP00000420312; ENSG00000175066 [Q6ZS86-2]
GeneIDi256356
KEGGihsa:256356
UCSCiuc003euq.2 human [Q6ZS86-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
256356
DisGeNETi256356

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GK5
HGNCiHGNC:28635 GK5
HPAiHPA042606
HPA057998
neXtProtiNX_Q6ZS86
OpenTargetsiENSG00000175066
PharmGKBiPA162389723

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2517 Eukaryota
COG0554 LUCA
GeneTreeiENSGT00950000182753
HOGENOMiHOG000222134
InParanoidiQ6ZS86
KOiK19583
OMAiGKPFHNF
OrthoDBi519426at2759
PhylomeDBiQ6ZS86
TreeFamiTF321504

Enzyme and pathway databases

UniPathwayiUPA00618;UER00672

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
GK5 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
256356

Protein Ontology

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PROi
PR:Q6ZS86

Gene expression databases

BgeeiENSG00000175066 Expressed in 180 organ(s), highest expression level in C1 segment of cervical spinal cord
ExpressionAtlasiQ6ZS86 baseline and differential
GenevisibleiQ6ZS86 HS

Family and domain databases

CDDicd07793 FGGY_GK5_metazoa, 1 hit
InterProiView protein in InterPro
IPR000577 Carb_kinase_FGGY
IPR018485 Carb_kinase_FGGY_C
IPR018483 Carb_kinase_FGGY_CS
IPR018484 Carb_kinase_FGGY_N
IPR037444 GK5_FGGY
PfamiView protein in Pfam
PF02782 FGGY_C, 1 hit
PF00370 FGGY_N, 1 hit
PIRSFiPIRSF000538 GlpK, 1 hit
PROSITEiView protein in PROSITE
PS00445 FGGY_KINASES_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGLPK5_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZS86
Secondary accession number(s): B2R9I2
, D3DNG2, Q8N2A7, Q8N5E6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: June 28, 2011
Last modified: July 31, 2019
This is version 131 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
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