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Entry version 97 (10 Apr 2019)
Sequence version 2 (10 Aug 2010)
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Protein

Protein ITPRID1

Gene

ITPRID1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein ITPRID1Curated
Alternative name(s):
Coiled-coil domain-containing protein 129
ITPR-interacting domain-containing protein 1Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ITPRID1Imported
Synonyms:CCDC129Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000180347.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:27363 ITPRID1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZRS4

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
223075

Open Targets

More...
OpenTargetsi
ENSG00000180347

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162381298

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
CCDC129

Domain mapping of disease mutations (DMDM)

More...
DMDMi
302393683

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002709631 – 1044Protein ITPRID1Add BLAST1044

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZRS4

PeptideAtlas

More...
PeptideAtlasi
Q6ZRS4

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZRS4

ProteomicsDB human proteome resource

More...
ProteomicsDBi
68165
68166 [Q6ZRS4-2]
68167 [Q6ZRS4-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZRS4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZRS4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000180347 Expressed in 51 organ(s), highest expression level in minor salivary gland

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZRS4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZRS4 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA024103

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000395835

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
Q6ZRS4

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZRS4

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili896 – 937Sequence analysisAdd BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi793 – 834Cys-richAdd BLAST42

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IIRH Eukaryota
ENOG410YK4C LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161762

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000111385

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG080711

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZRS4

Identification of Orthologs from Complete Genome Data

More...
OMAi
LEFWEKD

Database of Orthologous Groups

More...
OrthoDBi
159347at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZRS4

TreeFam database of animal gene trees

More...
TreeFami
TF331566

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029325 ITPR-bd
IPR029326 SSFA2_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14722 KRAP_IP3R_bind, 1 hit
PF14723 SSFA2_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01257 KRAP_IP3R_bind, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6ZRS4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MMAQKSQGSD NLQEGQEKSK REILKCTKSA WAPLDEWLPP DPEEESQSLT
60 70 80 90 100
IPMLEDSKQE SIQQWLDSGF FVSANENFQQ VIDRTVSLYE QGMVQMTVKD
110 120 130 140 150
YMRSLHQFSE TPILSRGTSF NSCYSTASVP QSIPEWLEFW EIDPVEILLD
160 170 180 190 200
LGFGADEPDI CMQIPARFLG CGSAARGINI RVFLEAQKQR MDIENPNLYG
210 220 230 240 250
RFRQLEILDH VTNAFSSLLS DVSILPNRAE EKAGGESVQR TSVSAAKEHR
260 270 280 290 300
RRMGKLLRRA SKQNIRRDCN PEVSESFKVK DEVFVPFTKP WDCGAELAAT
310 320 330 340 350
SINHKQNHLS LSVEHQSLQA CDDLLPYPPH GLLSKQWPCS SMPAKQAPPS
360 370 380 390 400
CVSEGSVKGR TQKENLFQTN KLKSLSHLAG KGPDSFEMEE VQSFEEETGN
410 420 430 440 450
PLDMTSGTVG ARVDRANSCQ SDSSGFLEEP LEPLPLQMPS LPNSQSPAEN
460 470 480 490 500
GGRKPRDQSH SLVSSQDCQL ESDGPDSKSR ASMSFSSQEA NALEQRASVS
510 520 530 540 550
VMEEEFLLEA MEGPPELYIP DMACAKTTTR GECPRKDSHL WQLLPMPHAE
560 570 580 590 600
YEVTRPTATS KYDHPLGFMV THVTEMQDSF VRPEGAGKVQ SHHNESQRSP
610 620 630 640 650
GNDHTQDKFL HVDSEAPREE ESSGFCPHTN HSLLVPESSS QCIPKHSEIT
660 670 680 690 700
PYATDLAQTS EKLIPHLHKL PGDPAQVKSR SGTLGQILPG TEAEMENLPL
710 720 730 740 750
NTGSSRSVMT QMSSSLVSAA QRAVALGTGP RGTSLECTVC DPVTATETRL
760 770 780 790 800
GTKARQLNDA SIQTSALSNK TLTHGPQPLT KSVSLDSGFS SICPMGTCHA
810 820 830 840 850
IPAHCCICCH HHPHCHGERQ SPGPEPSVCR HCLCSLTGHQ EAQFMTTLKA
860 870 880 890 900
LQDTTVRELC SCTVHEMEAM KTICQSFREY LEEIEQHLMG QQALFSRDMS
910 920 930 940 950
EEEREEAEQL QTLREALRQQ VAELEFQLGD RAQQIREGIL LQLEVLTAEP
960 970 980 990 1000
PEHYSNLHQY NWIEESNGQT SCSKIHPGMA PRTVFPPDDG QEAPCSGGTQ
1010 1020 1030 1040
LAAFTPPTLE NSTRMSPSSS AWAKLGPTPL SNCPVGEKDA DVFL
Length:1,044
Mass (Da):115,403
Last modified:August 10, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAADC89ADA69B8B7B
GO
Isoform 2 (identifier: Q6ZRS4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     244-391: Missing.

Note: No experimental confirmation available.
Show »
Length:896
Mass (Da):98,868
Checksum:iF0A45E42A3F5FA76
GO
Isoform 3 (identifier: Q6ZRS4-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-92: Missing.

Note: No experimental confirmation available.
Show »
Length:952
Mass (Da):104,885
Checksum:i27605E9AA15F2F61
GO
Isoform 4 (identifier: Q6ZRS4-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MPTTASCKTISLLKLLYSVSLQNYSPM
     998-1044: GTQLAAFTPP...VGEKDADVFL → ELLSAELDPF...FLKTQDSGLL

Note: No experimental confirmation available.
Show »
Length:1,062
Mass (Da):117,716
Checksum:iD141260E5E14596C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WUB1A0A087WUB1_HUMAN
Protein ITPRID1
ITPRID1
1,054Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7EQ43E7EQ43_HUMAN
Protein ITPRID1
ITPRID1
168Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ERG9E7ERG9_HUMAN
Protein ITPRID1
ITPRID1
163Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
B8ZZ49B8ZZ49_HUMAN
Protein ITPRID1
ITPRID1
142Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAG65223 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti802P → S in BAC87235 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03366032A → D2 PublicationsCorresponds to variant dbSNP:rs7811042Ensembl.1
Natural variantiVAR_035496105L → V in a colorectal cancer sample; somatic mutation. 1 Publication1
Natural variantiVAR_063505377H → R2 PublicationsCorresponds to variant dbSNP:rs10252720Ensembl.1
Natural variantiVAR_033661490A → V2 PublicationsCorresponds to variant dbSNP:rs4141001Ensembl.1
Natural variantiVAR_033662809C → Y2 PublicationsCorresponds to variant dbSNP:rs10247620Ensembl.1
Natural variantiVAR_033663887H → Y. Corresponds to variant dbSNP:rs7799540Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0395861 – 92Missing in isoform 3. 1 PublicationAdd BLAST92
Alternative sequenceiVSP_0450001M → MPTTASCKTISLLKLLYSVS LQNYSPM in isoform 4. 1 Publication1
Alternative sequenceiVSP_039587244 – 391Missing in isoform 2. 1 PublicationAdd BLAST148
Alternative sequenceiVSP_045001998 – 1044GTQLA…ADVFL → ELLSAELDPFFFSSKANNSA KDEKIKSKDFLKTQDSGLL in isoform 4. 1 PublicationAdd BLAST47

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AK095663 mRNA Translation: BAG53101.1
AK128026 mRNA Translation: BAC87235.1
AK295011 mRNA Translation: BAG58071.1
AK304387 mRNA Translation: BAG65223.1 Different initiation.
AC005090 Genomic DNA No translation available.
AC006044 Genomic DNA No translation available.
BC132719 mRNA Translation: AAI32720.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS5435.2 [Q6ZRS4-1]
CCDS59050.1 [Q6ZRS4-4]

NCBI Reference Sequences

More...
RefSeqi
NP_001244896.1, NM_001257967.2
NP_001244897.1, NM_001257968.2 [Q6ZRS4-4]
NP_919276.2, NM_194300.4 [Q6ZRS4-1]
XP_011513515.1, XM_011515213.1 [Q6ZRS4-1]
XP_016867360.1, XM_017011871.1 [Q6ZRS4-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.224269

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000319386; ENSP00000313062; ENSG00000180347 [Q6ZRS4-2]
ENST00000407970; ENSP00000384416; ENSG00000180347 [Q6ZRS4-1]
ENST00000409210; ENSP00000387214; ENSG00000180347 [Q6ZRS4-3]
ENST00000451887; ENSP00000395835; ENSG00000180347 [Q6ZRS4-4]

Database of genes from NCBI RefSeq genomes

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GeneIDi
223075

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:223075

UCSC genome browser

More...
UCSCi
uc003tci.2 human [Q6ZRS4-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK095663 mRNA Translation: BAG53101.1
AK128026 mRNA Translation: BAC87235.1
AK295011 mRNA Translation: BAG58071.1
AK304387 mRNA Translation: BAG65223.1 Different initiation.
AC005090 Genomic DNA No translation available.
AC006044 Genomic DNA No translation available.
BC132719 mRNA Translation: AAI32720.1
CCDSiCCDS5435.2 [Q6ZRS4-1]
CCDS59050.1 [Q6ZRS4-4]
RefSeqiNP_001244896.1, NM_001257967.2
NP_001244897.1, NM_001257968.2 [Q6ZRS4-4]
NP_919276.2, NM_194300.4 [Q6ZRS4-1]
XP_011513515.1, XM_011515213.1 [Q6ZRS4-1]
XP_016867360.1, XM_017011871.1 [Q6ZRS4-1]
UniGeneiHs.224269

3D structure databases

ProteinModelPortaliQ6ZRS4
SMRiQ6ZRS4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000395835

PTM databases

iPTMnetiQ6ZRS4
PhosphoSitePlusiQ6ZRS4

Polymorphism and mutation databases

BioMutaiCCDC129
DMDMi302393683

Proteomic databases

PaxDbiQ6ZRS4
PeptideAtlasiQ6ZRS4
PRIDEiQ6ZRS4
ProteomicsDBi68165
68166 [Q6ZRS4-2]
68167 [Q6ZRS4-3]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000319386; ENSP00000313062; ENSG00000180347 [Q6ZRS4-2]
ENST00000407970; ENSP00000384416; ENSG00000180347 [Q6ZRS4-1]
ENST00000409210; ENSP00000387214; ENSG00000180347 [Q6ZRS4-3]
ENST00000451887; ENSP00000395835; ENSG00000180347 [Q6ZRS4-4]
GeneIDi223075
KEGGihsa:223075
UCSCiuc003tci.2 human [Q6ZRS4-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
223075
DisGeNETi223075
EuPathDBiHostDB:ENSG00000180347.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
CCDC129

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0006576
HGNCiHGNC:27363 ITPRID1
HPAiHPA024103
neXtProtiNX_Q6ZRS4
OpenTargetsiENSG00000180347
PharmGKBiPA162381298

GenAtlas: human gene database

More...
GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IIRH Eukaryota
ENOG410YK4C LUCA
GeneTreeiENSGT00940000161762
HOGENOMiHOG000111385
HOVERGENiHBG080711
InParanoidiQ6ZRS4
OMAiLEFWEKD
OrthoDBi159347at2759
PhylomeDBiQ6ZRS4
TreeFamiTF331566

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CCDC129 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
223075

Protein Ontology

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PROi
PR:Q6ZRS4

Gene expression databases

BgeeiENSG00000180347 Expressed in 51 organ(s), highest expression level in minor salivary gland
ExpressionAtlasiQ6ZRS4 baseline and differential
GenevisibleiQ6ZRS4 HS

Family and domain databases

InterProiView protein in InterPro
IPR029325 ITPR-bd
IPR029326 SSFA2_C
PfamiView protein in Pfam
PF14722 KRAP_IP3R_bind, 1 hit
PF14723 SSFA2_C, 1 hit
SMARTiView protein in SMART
SM01257 KRAP_IP3R_bind, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiITPI1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZRS4
Secondary accession number(s): A2RU17
, B3KTI9, B4DHB0, B4E2R1, F5H3V5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: August 10, 2010
Last modified: April 10, 2019
This is version 97 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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