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UniProtKB - Q6ZRQ5 (MMS22_HUMAN)

Entry version 120 (16 Oct 2019)
Sequence version 3 (15 Dec 2009)
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Protein

Protein MMS22-like

Gene

MMS22L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA.3 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDNA damage, DNA repair

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein MMS22-like
Alternative name(s):
Methyl methanesulfonate-sensitivity protein 22-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MMS22L
Synonyms:C6orf167
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:21475 MMS22L

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		615614 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6ZRQ5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		253714

Open Targets

More...OpenTargetsi		ENSG00000146263

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134878007

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6ZRQ5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MMS22L

Domain mapping of disease mutations (DMDM)

More...DMDMi		281185507

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002602161 – 1243Protein MMS22-likeAdd BLAST1243

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6ZRQ5

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6ZRQ5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6ZRQ5

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6ZRQ5

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6ZRQ5

PeptideAtlas

More...PeptideAtlasi		Q6ZRQ5

PRoteomics IDEntifications database

More...PRIDEi		Q6ZRQ5

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		68153

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6ZRQ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6ZRQ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000146263 Expressed in 93 organ(s), highest expression level in kidney

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6ZRQ5 baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA067042

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the MMS22L-TONSL complex, a complex at least composed of MMS22L and TONSL/NFKBIL2.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Q96HA75EBI-718662,EBI-1052467

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		128982, 29 interactors

Protein interaction database and analysis system

More...IntActi		Q6ZRQ5, 16 interactors

Molecular INTeraction database

More...MINTi		Q6ZRQ5

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000275053

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MMS22 family. MMS22L subfamily.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IEVD Eukaryota
ENOG410ZSY3 LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00390000011769

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6ZRQ5

Identification of Orthologs from Complete Genome Data

More...OMAi		CTKELWV

Database of Orthologous Groups

More...OrthoDBi		523276at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6ZRQ5

TreeFam database of animal gene trees

More...TreeFami		TF353832

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR042320 MMS22-like
IPR029424 MMS22L_C
IPR029425 MMS22L_N

The PANTHER Classification System

More...PANTHERi		PTHR28547 PTHR28547, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF14911 MMS22L_C, 1 hit
PF14910 MMS22L_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

Q6ZRQ5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENCSAASTF LTDSLELELG TEWCKPPYFS CAVDNRGGGK HFSGESYLCS 
        60         70         80         90        100
GALKRLILNL DPLPTNFEED TLEIFGIQWV TETALVNSSR ELFHLFRQQL 
       110        120        130        140        150
YNLETLLQSS CDFGKVSTLH CKADNIRQQC VLFLHYVKVF IFRYLKVQNA 
       160        170        180        190        200
ESHVPVHPYE ALEAQLPSVL IDELHGLLLY IGHLSELPSV NIGAFVNQNQ 
       210        220        230        240        250
IKLFPPSWHL LHLHLDIHWL VLEILYMLGE KLKQVVYGHQ FMNLASDNLT 
       260        270        280        290        300
NISLFEEHCE TLLCDLISLS LNRYDKVRSS ESLMSDQCPC LCIKELWVLL 
       310        320        330        340        350
IHLLDHRSKW FVSESFWNWL NKLLKTLLEK SSDRRRSSMP VIQSRDPLGF 
       360        370        380        390        400
SWWIITHVAS FYKFDRHGVP DEMRKVESNW NFVEELLKKS ISVQGVILEE 
       410        420        430        440        450
QLRMYLHCCL TLCDFWEPNI AIVTILWEYY SKNLNSSFSI SWLPFKGLAN 
       460        470        480        490        500
TMKSPLSMLE MVKTCCCDKQ DQELYKSSSS YTIFLCILAK VVKKAMKSNG 
       510        520        530        540        550
PHPWKQVKGR IYSKFHQKRM EELTEVGLQN FFSLFLLLAA VAEVEDVASH 
       560        570        580        590        600
VLDLLNFLKP AFVTSQRALI WKGHMAFLLM YAQKNLDIGV LAEKFSCAFR 
       610        620        630        640        650
EKAKEFLVSK NEEMVQRQTI WTLLSIYIDG VQEVFETSYC LYPSHEKLLN 
       660        670        680        690        700
DGFSMLLRAC RESELRTVLS FLQAVLARIR SMHQQLCQEL QRDNVDLFVQ 
       710        720        730        740        750
SSLSAKERHL AAVASALWRH FFSFLKSQRM SQVVPFSQLA DAAADFTLLA 
       760        770        780        790        800
MDMPSTAPSD FQPQPVISII QLFGWDDIIC PQVVARYLSH VLQNSTLCEA 
       810        820        830        840        850
LSHSGYVSFQ ALTVRSWIRC VLQMYIKNLS GPDDLLIDKN LEEAVEKEYM 
       860        870        880        890        900
KQLVKLTRLL FNLSEVKSIF SKAQVEYLSI SEDPKKALVR FFEAVGVTYG 
       910        920        930        940        950
NVQTLSDKSA MVTKSLEYLG EVLKYIKPYL GKKVFSAGLQ LTYGMMGILV 
       960        970        980        990       1000
KSWAQIFATS KAQKLLFRII DCLLLPHAVL QQEKELPAPM LSAIQKSLPL 
      1010       1020       1030       1040       1050
YLQGMCIVCC QSQNPNAYLN QLLGNVIEQY IGRFLPASPY VSDLGQHPVL 
      1060       1070       1080       1090       1100
LALRNTATIP PISSLKKCIV QVIRKSYLEY KGSSPPPRLA SILAFILQLF 
      1110       1120       1130       1140       1150
KETNTDIYEV ELLLPGILKC LVLVSEPQVK RLATENLQYM VKACQVGSEE 
      1160       1170       1180       1190       1200
EPSSQLTSVF RQFIQDYGMR YYYQVYSILE TVATLDQQVV IHLISTLTQS 
      1210       1220       1230       1240 
LKDSEQKWGL GRNIAQREAY SKLLSHLGQM GQDEMQRLEN DNT
Length:1,243
Mass (Da):142,321
Last modified:December 15, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB63CE3030701CD71
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E2QRD4E2QRD4_HUMAN
Protein MMS22-like
MMS22L
1,203Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H9KVD8H9KVD8_HUMAN
Protein MMS22-like
MMS22L
203Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y8J1H0Y8J1_HUMAN
Protein MMS22-like
MMS22L
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YAJ2H0YAJ2_HUMAN
Protein MMS22-like
MMS22L
322Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H9KVD7H9KVD7_HUMAN
Protein MMS22-like
MMS22L
140Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti292C → R in BAC87254 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_029013419N → D. Corresponds to variant dbSNP:rs9374435Ensembl.1
Natural variantiVAR_029014564T → M1 PublicationCorresponds to variant dbSNP:rs9481410Ensembl.1
Natural variantiVAR_029015875V → A1 PublicationCorresponds to variant dbSNP:rs1737145Ensembl.1
Natural variantiVAR_0290161015P → L. Corresponds to variant dbSNP:rs10484830Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK128060 mRNA Translation: BAC87254.1
AL023656 Genomic DNA No translation available.
AL353679 Genomic DNA No translation available.
AL590484 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48494.1
CH471051 Genomic DNA Translation: EAW48496.1
CR749603 mRNA Translation: CAH18398.1
CR749822 mRNA Translation: CAH18682.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS5039.1

NCBI Reference Sequences

More...RefSeqi		NP_940870.2, NM_198468.2
XP_006715493.1, XM_006715430.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000275053; ENSP00000275053; ENSG00000146263

Database of genes from NCBI RefSeq genomes

More...GeneIDi		253714

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:253714

UCSC genome browser

More...UCSCi		uc003ppb.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128060 mRNA Translation: BAC87254.1
AL023656 Genomic DNA No translation available.
AL353679 Genomic DNA No translation available.
AL590484 Genomic DNA No translation available.
CH471051 Genomic DNA Translation: EAW48494.1
CH471051 Genomic DNA Translation: EAW48496.1
CR749603 mRNA Translation: CAH18398.1
CR749822 mRNA Translation: CAH18682.1
CCDSiCCDS5039.1
RefSeqiNP_940870.2, NM_198468.2
XP_006715493.1, XM_006715430.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGridi128982, 29 interactors
IntActiQ6ZRQ5, 16 interactors
MINTiQ6ZRQ5
STRINGi9606.ENSP00000275053

PTM databases

iPTMnetiQ6ZRQ5
PhosphoSitePlusiQ6ZRQ5

Polymorphism and mutation databases

BioMutaiMMS22L
DMDMi281185507

Proteomic databases

EPDiQ6ZRQ5
jPOSTiQ6ZRQ5
MassIVEiQ6ZRQ5
MaxQBiQ6ZRQ5
PaxDbiQ6ZRQ5
PeptideAtlasiQ6ZRQ5
PRIDEiQ6ZRQ5
ProteomicsDBi68153

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		253714

Genome annotation databases

EnsembliENST00000275053; ENSP00000275053; ENSG00000146263
GeneIDi253714
KEGGihsa:253714
UCSCiuc003ppb.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		253714
DisGeNETi253714

GeneCards: human genes, protein and diseases

More...GeneCardsi		MMS22L
HGNCiHGNC:21475 MMS22L
HPAiHPA067042
MIMi615614 gene
neXtProtiNX_Q6ZRQ5
OpenTargetsiENSG00000146263
PharmGKBiPA134878007

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IEVD Eukaryota
ENOG410ZSY3 LUCA
GeneTreeiENSGT00390000011769
InParanoidiQ6ZRQ5
OMAiCTKELWV
OrthoDBi523276at2759
PhylomeDBiQ6ZRQ5
TreeFamiTF353832

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		MMS22L human

The Gene Wiki collection of pages on human genes and proteins

More...GeneWikii		MMS22L

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		253714
PharosiQ6ZRQ5

Protein Ontology

More...PROi		PR:Q6ZRQ5

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000146263 Expressed in 93 organ(s), highest expression level in kidney
ExpressionAtlasiQ6ZRQ5 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR042320 MMS22-like
IPR029424 MMS22L_C
IPR029425 MMS22L_N
PANTHERiPTHR28547 PTHR28547, 1 hit
PfamiView protein in Pfam
PF14911 MMS22L_C, 1 hit
PF14910 MMS22L_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMMS22_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZRQ5
Secondary accession number(s): D6R9Y8
, D6RBQ4, E1P529, Q5THT2, Q68CQ6, Q68D32
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: December 15, 2009
Last modified: October 16, 2019
This is version 120 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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