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UniProtKB - Q6ZQX7 (LIAT1_HUMAN)

Entry version 110 (25 May 2022)
Sequence version 2 (05 Apr 2011)
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Protein

Protein LIAT1

Gene

LIAT1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in ATE1-mediated N-terminal arginylation.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Complete GO annotation on QuickGO ...

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6ZQX7

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...SignaLinki		Q6ZQX7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein LIAT1Curated
Alternative name(s):
Ligand of ATE1 proteinCurated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LIAT1Curated
Synonyms:C17orf97Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Chromosome 17, Unplaced

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:33800, C17orf97

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6ZQX7

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSG00000187624

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		400566

Open Targets

More...OpenTargetsi		ENSG00000187624

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162378582

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6ZQX7, Tdark

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		C17orf97

Domain mapping of disease mutations (DMDM)

More...DMDMi		327478504

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003402331 – 453Protein LIAT1Add BLAST453

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6ZQX7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6ZQX7

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6ZQX7

PeptideAtlas

More...PeptideAtlasi		Q6ZQX7

PRoteomics IDEntifications database

More...PRIDEi		Q6ZQX7

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		68096 [Q6ZQX7-1]
68097 [Q6ZQX7-2]
68098 [Q6ZQX7-3]
68099 [Q6ZQX7-4]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6ZQX7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6ZQX7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000187624, Expressed in testis and 176 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6ZQX7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6ZQX7, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000187624, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ATE1; it is not a substrate of LIAT1.

Interacts with JMJD6 and MRPS14 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		134634, 3 interactors

Protein interaction database and analysis system

More...IntActi		Q6ZQX7, 12 interactors

Molecular INTeraction database

More...MINTi		Q6ZQX7

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000353245

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6ZQX7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		Q6ZQX7

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati201 – 210110
Repeati211 – 220210
Repeati221 – 230310
Repeati231 – 240410
Repeati241 – 250510
Repeati251 – 260610
Repeati261 – 270710
Repeati271 – 280810
Repeati281 – 290910
Repeati291 – 3001010
Repeati301 – 3101110
Repeati311 – 3201210
Repeati321 – 3301310
Repeati331 – 3401410
Repeati341 – 3501510
Repeati351 – 3601610
Repeati361 – 3701710
Repeati371 – 3801810
Repeati381 – 3901910
Repeati391 – 4002010

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 152DisorderedSequence analysisAdd BLAST152
Regioni145 – 197Interaction with ATE1By similarityAdd BLAST53
Regioni201 – 40020 X 10 AA approximate tandem repeat of A-L-K-G-F-H-P-D-P-EAdd BLAST200
Regioni225 – 306DisorderedSequence analysisAdd BLAST82
Regioni320 – 432DisorderedSequence analysisAdd BLAST113

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi43 – 63Basic and acidic residuesSequence analysisAdd BLAST21
Compositional biasi82 – 97Basic residuesSequence analysisAdd BLAST16
Compositional biasi124 – 145Basic and acidic residuesSequence analysisAdd BLAST22
Compositional biasi320 – 400Basic and acidic residuesSequence analysisAdd BLAST81
Compositional biasi412 – 426Polar residuesSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

LIAT1 proteins of some primates, from macaques to humans, contain tandem repeats of a 10-residue sequence, whereas LIAT1 proteins of other mammals contain a single copy of this motif. Quantities of these repeats are, in general, different in LIAT1 of different primates. For example, there are 1, 4, 13, 13, 17, and 17 repeats in the gibbon, gorilla, orangutan, bonobo, neanderthal, and human LIAT1, respectively.1 Publication

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502SC86, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00440000038370

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_049741_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6ZQX7

Identification of Orthologs from Complete Genome Data

More...OMAi		LKGFHTD

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6ZQX7

TreeFam database of animal gene trees

More...TreeFami		TF337007

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR038794, LIAT1

The PANTHER Classification System

More...PANTHERi		PTHR36474, PTHR36474, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6ZQX7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
METRGPGLAV RAESRRLVGI GPRAPPGRVG LQPSGRLDRR GGAGTMGYKD 
        60         70         80         90        100
NDGEEEEREG GAAGPRGSRL PPITGGASEL AKRKVKKKKR KKKTKGSGKG 
       110        120        130        140        150
DDKHQSQSLK SQPLSSSFHD ILSPCKERGP KPEHRQSKVE KKHLPSDSST 
       160        170        180        190        200
VSLPDFAEIE NLANRINESL RWDGILADPE AEKERIRIYK LNRRKRYRCL 
       210        220        230        240        250
ALKGFHPDPE ALKGFHPDPD ALKGFHPDPE ALKGFHPDPE ALKGFHPDPE 
       260        270        280        290        300
ALKGFHPDPE ALKGIHPDPE ALKGIHPDPE ALKGFHPDPE ALKGFHPDPE 
       310        320        330        340        350
ALKGFHTDPE ALKGFHIDPE ALKGFHPDPK ALKGFHPDPK ALKGFHTDPE 
       360        370        380        390        400
ALKGFHPDPK ALKGFHPDPE ALKGFHPDPE ALKGFHPDPE ALKGFHTDPN 
       410        420        430        440        450
AEEAPENLPY LSDKDGSSSH RQPTSKAECP NLCFEGNLTP KLLHSDLAPT 

LLE
Length:453
Mass (Da):49,656
Last modified:April 5, 2011 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB6EB88592B0ED514
GO
Isoform 2 (identifier: Q6ZQX7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     256-265: Missing.
     348-367: Missing.

Show »
Length:423
Mass (Da):46,414
Checksum:iADA8A85C29D031A7
GO
Isoform 3 (identifier: Q6ZQX7-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     201-220: Missing.

Show »
Length:433
Mass (Da):47,486
Checksum:i36C094BE419E942D
GO
Isoform 4 (identifier: Q6ZQX7-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     236-265: Missing.

Show »
Length:423
Mass (Da):46,413
Checksum:i2011EBEE9EDE9001
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C5B9H7C5B9_HUMAN
Chromosome 17 open reading frame 97
C17orf97
209Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
I3L0T0I3L0T0_HUMAN
Chromosome 17 open reading frame 97
C17orf97
153Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti105Q → L in AAI41807 (PubMed:15489334).Curated1
Sequence conflicti114L → P in AAH57385 (PubMed:15489334).Curated1
Sequence conflicti240E → D in AAH57385 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_04400856E → K1 PublicationCorresponds to variant dbSNP:rs4581766Ensembl.1
Natural variantiVAR_044009220D → E2 PublicationsCorresponds to variant dbSNP:rs35229416Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_034195201 – 220Missing in isoform 3. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_034196236 – 265Missing in isoform 4. 1 PublicationAdd BLAST30
Alternative sequenceiVSP_034197256 – 265Missing in isoform 2. 1 Publication10
Alternative sequenceiVSP_034198348 – 367Missing in isoform 2. 1 PublicationAdd BLAST20

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK128660 mRNA Translation: BAC87555.1
AC141424 Genomic DNA No translation available.
BC057385 mRNA Translation: AAH57385.1
BC070116 mRNA Translation: AAH70116.2
BC141806 mRNA Translation: AAI41807.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32519.2 [Q6ZQX7-4]

NCBI Reference Sequences

More...RefSeqi		NP_001013694.4, NM_001013672.4 [Q6ZQX7-4]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000360127.7; ENSP00000353245.6; ENSG00000187624.9 [Q6ZQX7-4]
ENST00000639297.2; ENSP00000491943.1; ENSG00000283985.2 [Q6ZQX7-4]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		400566

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:400566

Matched Annotation from NCBI and EMBL-EBI (MANE) - Phase one

More...MANE-Selecti		ENST00000360127.7; ENSP00000353245.6; NM_001013672.5; NP_001013694.4 [Q6ZQX7-4]

UCSC genome browser

More...UCSCi		uc021tna.1, human [Q6ZQX7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128660 mRNA Translation: BAC87555.1
AC141424 Genomic DNA No translation available.
BC057385 mRNA Translation: AAH57385.1
BC070116 mRNA Translation: AAH70116.2
BC141806 mRNA Translation: AAI41807.1
CCDSiCCDS32519.2 [Q6ZQX7-4]
RefSeqiNP_001013694.4, NM_001013672.4 [Q6ZQX7-4]

3D structure databases

AlphaFoldDBiQ6ZQX7
ModBaseiSearch...
SWISS-MODEL-WorkspaceiSubmit a new modelling project...

Protein-protein interaction databases

BioGRIDi134634, 3 interactors
IntActiQ6ZQX7, 12 interactors
MINTiQ6ZQX7
STRINGi9606.ENSP00000353245

PTM databases

iPTMnetiQ6ZQX7
PhosphoSitePlusiQ6ZQX7

Genetic variation databases

BioMutaiC17orf97
DMDMi327478504

Proteomic databases

EPDiQ6ZQX7
MassIVEiQ6ZQX7
MaxQBiQ6ZQX7
PeptideAtlasiQ6ZQX7
PRIDEiQ6ZQX7
ProteomicsDBi68096 [Q6ZQX7-1]
68097 [Q6ZQX7-2]
68098 [Q6ZQX7-3]
68099 [Q6ZQX7-4]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		10251, 46 antibodies from 12 providers

The DNASU plasmid repository

More...DNASUi		400566

Genome annotation databases

EnsembliENST00000360127.7; ENSP00000353245.6; ENSG00000187624.9 [Q6ZQX7-4]
ENST00000639297.2; ENSP00000491943.1; ENSG00000283985.2 [Q6ZQX7-4]
GeneIDi400566
KEGGihsa:400566
MANE-SelectiENST00000360127.7; ENSP00000353245.6; NM_001013672.5; NP_001013694.4 [Q6ZQX7-4]
UCSCiuc021tna.1, human [Q6ZQX7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		400566
DisGeNETi400566

GeneCards: human genes, protein and diseases

More...GeneCardsi		C17orf97
HGNCiHGNC:33800, C17orf97
HPAiENSG00000187624, Tissue enriched (testis)
neXtProtiNX_Q6ZQX7
OpenTargetsiENSG00000187624
PharmGKBiPA162378582
VEuPathDBiHostDB:ENSG00000187624

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG502SC86, Eukaryota
GeneTreeiENSGT00440000038370
HOGENOMiCLU_049741_0_0_1
InParanoidiQ6ZQX7
OMAiLKGFHTD
PhylomeDBiQ6ZQX7
TreeFamiTF337007

Enzyme and pathway databases

PathwayCommonsiQ6ZQX7
SignaLinkiQ6ZQX7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		400566, 14 hits in 1042 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		400566
PharosiQ6ZQX7, Tdark

Protein Ontology

More...PROi		PR:Q6ZQX7
RNActiQ6ZQX7, protein

Gene expression databases

BgeeiENSG00000187624, Expressed in testis and 176 other tissues
ExpressionAtlasiQ6ZQX7, baseline and differential
GenevisibleiQ6ZQX7, HS

Family and domain databases

InterProiView protein in InterPro
IPR038794, LIAT1
PANTHERiPTHR36474, PTHR36474, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLIAT1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZQX7
Secondary accession number(s): A5D8T6, Q6NSI2, Q6PFW9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: April 5, 2011
Last modified: May 25, 2022
This is version 110 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human entries with genetic variants
    List of human entries with genetic variants
  3. Human variants curated from literature reports
    Index of human variants curated from literature reports
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