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UniProtKB - Q6ZQH8 (NU188_MOUSE)

Entry version 111 (10 Feb 2021)
Sequence version 2 (11 Sep 2007)
Previous versions | rss
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Protein

Nucleoporin NUP188

Gene

Nup188

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the nuclear pore complex (NPC), a complex required for the trafficking across the nuclear envelope. Required for proper protein transport into the nucleus.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-159227, Transport of the SLBP independent Mature mRNA
R-MMU-159230, Transport of the SLBP Dependant Mature mRNA
R-MMU-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859, snRNP Assembly
R-MMU-3108214, SUMOylation of DNA damage response and repair proteins
R-MMU-3232142, SUMOylation of ubiquitinylation proteins
R-MMU-3301854, Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453, Regulation of HSF1-mediated heat shock response
R-MMU-4085377, SUMOylation of SUMOylation proteins
R-MMU-4551638, SUMOylation of chromatin organization proteins
R-MMU-4570464, SUMOylation of RNA binding proteins
R-MMU-4615885, SUMOylation of DNA replication proteins
R-MMU-5578749, Transcriptional regulation by small RNAs
R-MMU-9615933, Postmitotic nuclear pore complex (NPC) reformation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleoporin NUP188Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nup188
Synonyms:Kiaa0169
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:2446190, Nup188

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nuclear pore complex, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002991732 – 1759Nucleoporin NUP188Add BLAST1758

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineBy similarity1
Modified residuei1719PhosphoserineCombined sources1
Modified residuei1727PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6ZQH8

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6ZQH8

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6ZQH8

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6ZQH8

PeptideAtlas

More...PeptideAtlasi		Q6ZQH8

PRoteomics IDEntifications database

More...PRIDEi		Q6ZQH8

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6ZQH8

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6ZQH8

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000052533, Expressed in embryonic stem cell and 231 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6ZQH8, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6ZQH8, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the nuclear pore complex (NPC).

By similarity

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		230667, 27 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-4474, Nuclear pore complex

Protein interaction database and analysis system

More...IntActi		Q6ZQH8, 23 interactors

Molecular INTeraction database

More...MINTi		Q6ZQH8

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000065836

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6ZQH8, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Nup188 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4833, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000005742

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_002623_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6ZQH8

Identification of Orthologs from Complete Genome Data

More...OMAi		MENCFYV

Database of Orthologous Groups

More...OrthoDBi		79804at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6ZQH8

TreeFam database of animal gene trees

More...TreeFami		TF101106

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016024, ARM-type_fold
IPR018864, Nucleoporin_Nup188

Pfam protein domain database

More...Pfami		View protein in Pfam
PF10487, Nup188, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6ZQH8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAAAGGPCV RSSRELWTIL LGRSALRELN QIEAELNKYW QRLLEGLSYY 
        60         70         80         90        100
KPPSPSSAER VKANKDVASP LKELGLRVSK FLGLDEEQSV QLLQCYLQED 
       110        120        130        140        150
YRGTRDSLKT VLQDERQSQA LTLKIADYYY EERTCILRCV LHLLTYFQDE 
       160        170        180        190        200
RHPYRAEYAD CVDKLEKELV LKYRQQFEEL YRTEAPTWET HGNLMTERQV 
       210        220        230        240        250
SRWLVQCLRE QSMLLEIIFL YYAYFEMAPS DLLVLTKMFK EQGFGSRQTS 
       260        270        280        290        300
RHLVGGTMDP FVDRIGYFSA LILVEGMDIE SLHKYALDDR RELHQFAQDG 
       310        320        330        340        350
LICQDMDRAM LTLGDIPHHA PVLLAWALLR HTLSPEETSS VVRKIGGTAI 
       360        370        380        390        400
QLNVFQYLTR LLRSLASGGN DCTTSTACMC VYGLLSFALT SLELHTLGNQ 
       410        420        430        440        450
QDVIDTACEV LADPSLPELF WGTEPTSGLG IILDSVCGMF PHLLSPLLQL 
       460        470        480        490        500
LRALVSGKST AKKVYSFLDK MSFYNELHKH KPHDVLSHED GTLWRRQTPK 
       510        520        530        540        550
LLYPLGGQTN LRIPQGTVGQ VMLDDRAYLV RWEYSYSSWT LFTCEIEMLL 
       560        570        580        590        600
HVVSTADVIQ HCQRVKPIID LVHKVISTDL SIADCLLPIT SRIYMLLQRL 
       610        620        630        640        650
TTVISPPVNV IASCVNCLTV LAARNPAKVW TDLRHTGFLP FVAHPVSNMT 
       660        670        680        690        700
QMISAEGMNA GGYGSLLMNS EQPQGEYGVT IAFLRLVTTL VKGQLGSTQS 
       710        720        730        740        750
QGLVPCVMFV LKEMLPSYHK WRYNSHGVRE LIGCLILELI HAILNLCQET 
       760        770        780        790        800
ELHSSHTPSL PSLCICSLAY TEAGQTVISI MGIGVDTIDM VMAAQPRSDG 
       810        820        830        840        850
PEGQGQGQLL IKTVKLAFSV TNNVIRLKPP SNVVSPLEQA LTQHGAHGNN 
       860        870        880        890        900
LIAVLAKYIY HRHDPALPRL AIQLLKRLAT VAPMSVYACL GSDAAAIRDA 
       910        920        930        940        950
FLTRLQSKIE DMRIKVMILE FLTVAVETQP GLIELFLNLE VKDGSNGSKE 
       960        970        980        990       1000
FSLGVWSCLH VVLELIDSQQ QDRYWCPPLL HRAAIAFLHA LWQDRRDSAM 
      1010       1020       1030       1040       1050
LVLRTKPKFW ENLTSPLFGT LSPPSETSEP SVLETCALIM KIICLEIYYV 
      1060       1070       1080       1090       1100
VKGSLDQSLK DTLKKFSSEK RFAYWSGYVK SLAVYMADTE GSSCTSLLEY 
      1110       1120       1130       1140       1150
QMLVSAWRIL LIIAASHADV MHLTDMAVRR QLFLDVLDGT KALLLVAASV 
      1160       1170       1180       1190       1200
NCLRLGSMMC TLLLILLRQW KRELGAVEKI LGPLTEILEG VLQADQQLME 
      1210       1220       1230       1240       1250
KTKAKVFSAF ITVLQMKELR VGDIPQYSQL VLNVCETLQE EVIALFDQTR 
      1260       1270       1280       1290       1300
HSLASDSAAE DKDSMETDDC PRPRHKDQRD GVCVLGLHLA KELCEVDEDG 
      1310       1320       1330       1340       1350
DSWLQVTRRL PILPTLLTTL EVSLRMKQNL HFTEAALHLL LTLARTQQGA 
      1360       1370       1380       1390       1400
TAVAGAGITQ SICLPLLSVY QLSSNGTGQT PSTSRKSLDA PSWPGVYRLS 
      1410       1420       1430       1440       1450
MSLMERLLKT LRYNFLTEAL DFVGVHQERT LQCLNAVKTV QSLACLEEAD 
      1460       1470       1480       1490       1500
HTVGFILQLS HFRKEWHFHL PQLMRDVQVN LGYLCQACTS LLHSRKMLQH 
      1510       1520       1530       1540       1550
YLQNKNGDGL PSAVTPRAQR PSTTTTTTTT TTALATPAGC SSKQPTADTE 
      1560       1570       1580       1590       1600
ASEQRALHTV QYGLLKILSR TLAALRHFTP DVCQILLDQS LDLAEYNFLF 
      1610       1620       1630       1640       1650
ALSFTTPTFD SEVAPSFGTL LATVNVALNM LGELDKKKES LTQAVGLSTQ 
      1660       1670       1680       1690       1700
AEGTRTLKSL LMFTMENCFY LLISQAVRYL RDPAVHPRDK QRMKQELSSE 
      1710       1720       1730       1740       1750
LSTLLSSLSR YFRRGAPSSP AAGVLPSPQG KATSLSKASP ESQEPLIQLV 

QAFVRHVQR
Length:1,759
Mass (Da):196,696
Last modified:September 11, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9067785281A0BF98
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F2Z4A7F2Z4A7_MOUSE
Nucleoporin NUP188
Nup188
118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
J3JSA4J3JSA4_MOUSE
Nucleoporin NUP188
Nup188
119Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2AWI5A2AWI5_MOUSE
Nucleoporin NUP188
Nup188
155Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH25526 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC97883 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti798S → R in BAC34911 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AK129073 mRNA Translation: BAC97883.1 Different initiation.
AL954388 Genomic DNA No translation available.
BC025526 mRNA Translation: AAH25526.1 Different initiation.
BC050199 mRNA Translation: AAH50199.1
BC096591 mRNA Translation: AAH96591.1
AK052272 mRNA Translation: BAC34911.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS15878.1

NCBI Reference Sequences

More...RefSeqi		NP_938046.2, NM_198304.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000064447; ENSMUSP00000065836; ENSMUSG00000052533

Database of genes from NCBI RefSeq genomes

More...GeneIDi		227699

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:227699

UCSC genome browser

More...UCSCi		uc008jcb.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129073 mRNA Translation: BAC97883.1 Different initiation.
AL954388 Genomic DNA No translation available.
BC025526 mRNA Translation: AAH25526.1 Different initiation.
BC050199 mRNA Translation: AAH50199.1
BC096591 mRNA Translation: AAH96591.1
AK052272 mRNA Translation: BAC34911.1
CCDSiCCDS15878.1
RefSeqiNP_938046.2, NM_198304.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi230667, 27 interactors
ComplexPortaliCPX-4474, Nuclear pore complex
IntActiQ6ZQH8, 23 interactors
MINTiQ6ZQH8
STRINGi10090.ENSMUSP00000065836

PTM databases

iPTMnetiQ6ZQH8
PhosphoSitePlusiQ6ZQH8

Proteomic databases

EPDiQ6ZQH8
jPOSTiQ6ZQH8
MaxQBiQ6ZQH8
PaxDbiQ6ZQH8
PeptideAtlasiQ6ZQH8
PRIDEiQ6ZQH8

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		34836, 84 antibodies

Genome annotation databases

EnsembliENSMUST00000064447; ENSMUSP00000065836; ENSMUSG00000052533
GeneIDi227699
KEGGimmu:227699
UCSCiuc008jcb.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		23511
MGIiMGI:2446190, Nup188

Rodent Unidentified Gene-Encoded large proteins database

More...Rougei		Search...

Phylogenomic databases

eggNOGiKOG4833, Eukaryota
GeneTreeiENSGT00390000005742
HOGENOMiCLU_002623_1_0_1
InParanoidiQ6ZQH8
OMAiMENCFYV
OrthoDBi79804at2759
PhylomeDBiQ6ZQH8
TreeFamiTF101106

Enzyme and pathway databases

ReactomeiR-MMU-159227, Transport of the SLBP independent Mature mRNA
R-MMU-159230, Transport of the SLBP Dependant Mature mRNA
R-MMU-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859, snRNP Assembly
R-MMU-3108214, SUMOylation of DNA damage response and repair proteins
R-MMU-3232142, SUMOylation of ubiquitinylation proteins
R-MMU-3301854, Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453, Regulation of HSF1-mediated heat shock response
R-MMU-4085377, SUMOylation of SUMOylation proteins
R-MMU-4551638, SUMOylation of chromatin organization proteins
R-MMU-4570464, SUMOylation of RNA binding proteins
R-MMU-4615885, SUMOylation of DNA replication proteins
R-MMU-5578749, Transcriptional regulation by small RNAs
R-MMU-9615933, Postmitotic nuclear pore complex (NPC) reformation

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		227699, 7 hits in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Nup188, mouse

Protein Ontology

More...PROi		PR:Q6ZQH8
RNActiQ6ZQH8, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000052533, Expressed in embryonic stem cell and 231 other tissues
ExpressionAtlasiQ6ZQH8, baseline and differential
GenevisibleiQ6ZQH8, MM

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR018864, Nucleoporin_Nup188
PfamiView protein in Pfam
PF10487, Nup188, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNU188_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZQH8
Secondary accession number(s): Q4VA15
, Q80UL4, Q8C7A1, Q8R3F1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: February 10, 2021
This is version 111 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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