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Entry version 92 (02 Dec 2020)
Sequence version 1 (05 Jul 2004)
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Protein
Submitted name:

MKIAA0791 protein

Gene

Nup155

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
MKIAA0791 proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nup155Imported
Synonyms:mKIAA0791Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2181182, Nup155

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nuclear pore complexARBA annotation, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZQ45

PeptideAtlas

More...
PeptideAtlasi
Q6ZQ45

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZQ45

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZQ45, MM

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini111 – 540Nucleoporin_NInterPro annotationAdd BLAST430
Domaini837 – 1209Nucleoporin_CInterPro annotationAdd BLAST373

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni636 – 662DisorderedSequence analysisAdd BLAST27
Regioni1017 – 1044DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili48 – 68Sequence analysisAdd BLAST21
Coiled coili1173 – 1193Sequence analysisAdd BLAST21

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the non-repetitive/WGA-negative nucleoporin family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
140051at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.1880, 1 hit
1.25.40.440, 1 hit
1.25.40.450, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007187, Nucleoporin_Nup133/Nup155_C
IPR014908, Nucleoporin_Nup133/Nup155_N
IPR004870, Nucleoporin_Nup155
IPR042533, Nucleoporin_Nup155_C_1
IPR042537, Nucleoporin_Nup155_C_2
IPR042538, Nucleoporin_Nup155_C_3

The PANTHER Classification System

More...
PANTHERi
PTHR10350, PTHR10350, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03177, Nucleoporin_C, 1 hit
PF08801, Nucleoporin_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q6ZQ45-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
RVPRSGFGLS SFFSRFSTGL ECFYKAVATI ADMPSVLGSM MVASTSAAAS
60 70 80 90 100
LQEALENAGR LIDRQLQEDR MYPDLSELLM VSAPNSPTVS GMSDMDYPLQ
110 120 130 140 150
GPGLLSVPSL PEISTIRRVP LPPELVEQFG HMQCNCMMGV FPPISRAWLT
160 170 180 190 200
IDSDIFMWNY EDGGDLAYFD GLSETILAVG LVKPKAGIFQ PHVRHLLVLA
210 220 230 240 250
TPVDIVILGL SYANVQTGSG ILNDSMCGGM QLLPDPLYSL PTDNTYLLTI
260 270 280 290 300
TSTDNGRIFL AGKDGCLYEV AYQAEAGWFS QRCRKINHSK SSLSFLVPSL
310 320 330 340 350
LQFTFSEDDP IVQIEIDNSR NILYTRSEKG VIQVYDLGHD GQGMSRVASV
360 370 380 390 400
SQNAIVSAAG NIARTIDRSV FKPIVQIAVI ESSESLDCQL LAVTHAGVRL
410 420 430 440 450
YFSTCPFRQP LARPNTLTLV HVRLPPGFSA SSTVEKPSKV HKALYSKGIL
460 470 480 490 500
LMTASENEDN DILWCVNHDT FPFQKPMMET QMTTRVDGHS WALSAIDELK
510 520 530 540 550
VDKIITPLNK DHIPITDSPV VVQQHMLPPK KFVLLSAQGS LMFHKLRPVD
560 570 580 590 600
QLRHLLVSNV GGDGEEIERF FKLHQEDQAC ATCLILACST AACDREVSAW
610 620 630 640 650
ATRAFFRYGG EAQMRFPATL PTPSNVGPIL GSPMYSSSPV PSGSPYPNPS
660 670 680 690 700
SLGTPSHGAQ PPTMSTPMCA VGSPAMQAAS MSGLTGPEIV YSGKHNGICI
710 720 730 740 750
YFSRIMGNIW DASLVVERVF KSSNREITAI ESSVPVQLLE SVLQELKGLQ
760 770 780 790 800
EFLDRNSQFS GGPLGNPNTT ARVQQRLVGF MRPENGNTQQ MQQELQRKFQ
810 820 830 840 850
EAQLSEKISL QAIQQLVRKS YQALALWKLL CEHQFSVIVG ELQKEFQEQL
860 870 880 890 900
KITTFKDLVI RDKEVTGALI ASLINCYIRD NAAVDGISLH LQDTCPLLYS
910 920 930 940 950
TDDAVCSKAN ELLQRSRQVQ SKTERERMLR ESLKEYQKIS NQVDLPSVCA
960 970 980 990 1000
QYRQVRFYEG VVELSLTAAE KKDPQGLGLH FYKHGEPEED VVGLQTFQER
1010 1020 1030 1040 1050
LNSYKCITDT LQELVNQSKA APQSPSVPKK PGPPVLSSDP NMLSNEEAGH
1060 1070 1080 1090 1100
HFEQMLKLAQ RSKDELFSIA LYNWLIQADL ADKLLQIASP FLEPHLVRMA
1110 1120 1130 1140 1150
RVDQNRVRYM DLLWRYYEKN RSFSSAARVL SKLADMHSTE ISLQQRLEYI
1160 1170 1180 1190 1200
ARAILSAKSS TAISSIAADG EFLHELEEKM EVARIQLQIQ ETLQRQYSHH
1210 1220 1230 1240 1250
SSVQDAISQL DSELMDITKL YGEFADPFKL AECKLAVIHC AGYSDPILVH
1260 1270 1280 1290 1300
TLWQDIIEKE LNDSVALSSS DRMHALSLKL VLLGKIYAGT PRFFPLDFIV
1310 1320 1330 1340 1350
QFLEQQVCTL NWDVGFVIQT MNEIGVPLPR LLEVYDQLFK SRDPFWNRVK
1360 1370 1380 1390 1400
SPLHLLDCIH VLLTRYVENP SLVLNCERRR FTNLCLDAVC GYLVELQSMS
1410 1420
SSVAVQAITG NFKSLQAKLE RLH
Length:1,423
Mass (Da):158,618
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA848C1FCA903B6D0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK129217 mRNA Translation: BAC98027.1

NCBI Reference Sequences

More...
RefSeqi
NP_573490.3, NM_133227.3

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
170762

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:170762

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK129217 mRNA Translation: BAC98027.1
RefSeqiNP_573490.3, NM_133227.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

MaxQBiQ6ZQ45
PeptideAtlasiQ6ZQ45
PRIDEiQ6ZQ45

Genome annotation databases

GeneIDi170762
KEGGimmu:170762

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9631
MGIiMGI:2181182, Nup155

Phylogenomic databases

OrthoDBi140051at2759

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
170762, 10 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Nup155, mouse

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

GenevisibleiQ6ZQ45, MM

Family and domain databases

Gene3Di1.20.120.1880, 1 hit
1.25.40.440, 1 hit
1.25.40.450, 1 hit
InterProiView protein in InterPro
IPR007187, Nucleoporin_Nup133/Nup155_C
IPR014908, Nucleoporin_Nup133/Nup155_N
IPR004870, Nucleoporin_Nup155
IPR042533, Nucleoporin_Nup155_C_1
IPR042537, Nucleoporin_Nup155_C_2
IPR042538, Nucleoporin_Nup155_C_3
PANTHERiPTHR10350, PTHR10350, 1 hit
PfamiView protein in Pfam
PF03177, Nucleoporin_C, 1 hit
PF08801, Nucleoporin_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6ZQ45_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZQ45
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: December 2, 2020
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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