UniProtKB - Q6ZP53 (Q6ZP53_HUMAN)
Protein
Submitted name:
cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
GO - Biological processi
- innate immune response Source: UniProtKB-KW
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotationARBA annotation |
Biological process | Immunity, Innate immunityARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ26493 fis, clone KDN06317, highly similar to Ras-GTPase-activating protein binding protein 1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Stress granule ARBA annotation
Other locations
- cytoplasmic stress granule Source: UniProtKB-SubCell
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 11 – 64 | NTF2InterPro annotationAdd BLAST | 54 | |
Domaini | 181 – 256 | RRMInterPro annotationAdd BLAST | 76 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 56 – 168 | DisorderedSequence analysisAdd BLAST | 113 | |
Regioni | 254 – 307 | DisorderedSequence analysisAdd BLAST | 54 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 57 – 72 | PolyampholyteSequence analysisAdd BLAST | 16 | |
Compositional biasi | 96 – 114 | AcidicSequence analysisAdd BLAST | 19 | |
Compositional biasi | 254 – 271 | PolyampholyteSequence analysisAdd BLAST | 18 |
Phylogenomic databases
OrthoDBi | 1526879at2759 |
Family and domain databases
CDDi | cd12463, RRM_G3BP1, 1 hit |
InterProi | View protein in InterPro IPR034375, G3BP1 IPR034374, G3BP1_RRM IPR002075, NTF2 IPR032710, NTF2-like_dom_sf IPR018222, Nuclear_transport_factor_2_euk IPR039539, Ras_GTPase_bind_prot IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR10693, PTHR10693, 3 hits PTHR10693:SF21, PTHR10693:SF21, 3 hits |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit PS50102, RRM, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6ZP53-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVMEKPSPLL VGREFVRQYY TLLNQAPDML HRFYGKNSSY VHGGLDSNGK
60 70 80 90 100
PADAVYGQKE IQEEKPEPVL EETAPDDSGT FYDQAVVSND MEEHLEEPVA
110 120 130 140 150
EPEPDPEPEP EQEPVSEIQE EKPEPESKPE SQIPPQRPQR DQRVREQRIN
160 170 180 190 200
IPPQRGPRPI REAGEQGDIE PRRMVRHPDS HQLFIGNLPH EVDKSELKDF
210 220 230 240 250
FQSYGNVVEL RINSGGKLPN FGFVVFDDSE PVQKVLSNRP IMFRGEVRLN
260 270 280 290 300
VEEKKTRAAR EGDRRDNRLR GPGGPRGGLG GGMRGPPRGG MVQKPGFGVG
RGLAPRQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK130003 mRNA Translation: BAC85272.1 |
RefSeqi | NP_005745.1, NM_005754.2 NP_938405.1, NM_198395.1 |
Genome annotation databases
GeneIDi | 10146 |
KEGGi | hsa:10146 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK130003 mRNA Translation: BAC85272.1 |
RefSeqi | NP_005745.1, NM_005754.2 NP_938405.1, NM_198395.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | Q6ZP53 |
Protocols and materials databases
DNASUi | 10146 |
Genome annotation databases
GeneIDi | 10146 |
KEGGi | hsa:10146 |
Organism-specific databases
CTDi | 10146 |
PharmGKBi | PA162389105 |
Phylogenomic databases
OrthoDBi | 1526879at2759 |
Miscellaneous databases
BioGRID-ORCSi | 10146, 26 hits in 845 CRISPR screens |
GenomeRNAii | 10146 |
Gene expression databases
Genevisiblei | Q6ZP53, HS |
Family and domain databases
CDDi | cd12463, RRM_G3BP1, 1 hit |
InterProi | View protein in InterPro IPR034375, G3BP1 IPR034374, G3BP1_RRM IPR002075, NTF2 IPR032710, NTF2-like_dom_sf IPR018222, Nuclear_transport_factor_2_euk IPR039539, Ras_GTPase_bind_prot IPR035979, RBD_domain_sf IPR000504, RRM_dom |
PANTHERi | PTHR10693, PTHR10693, 3 hits PTHR10693:SF21, PTHR10693:SF21, 3 hits |
Pfami | View protein in Pfam PF02136, NTF2, 1 hit PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54427, SSF54427, 1 hit SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50177, NTF2_DOMAIN, 1 hit PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6ZP53_HUMAN | |
Accessioni | Q6ZP53Primary (citable) accession number: Q6ZP53 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |