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Entry version 143 (07 Oct 2020)
Sequence version 2 (05 May 2009)
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Protein

Zinc finger protein 497

Gene

ZNF497

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri106 – 128C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri134 – 156C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri162 – 184C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri190 – 212C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri218 – 240C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6ZNH5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 497
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF497
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000174586.10

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23714, ZNF497

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZNH5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000174586

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134994387

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6ZNH5, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF497

Domain mapping of disease mutations (DMDM)

More...
DMDMi
229462815

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000476181 – 498Zinc finger protein 497Add BLAST498

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6ZNH5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6ZNH5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZNH5

PeptideAtlas

More...
PeptideAtlasi
Q6ZNH5

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZNH5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
68026

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZNH5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZNH5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000174586, Expressed in right uterine tube and 113 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZNH5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZNH5, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000174586, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127835, 41 interactors

Protein interaction database and analysis system

More...
IntActi
Q6ZNH5, 35 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000311183

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6ZNH5, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZNH5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri106 – 128C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri134 – 156C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri162 – 184C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri190 – 212C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri218 – 240C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 14PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000165876

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_44_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZNH5

Identification of Orthologs from Complete Genome Data

More...
OMAi
QMAPKEG

Database of Orthologous Groups

More...
OrthoDBi
1318335at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZNH5

TreeFam database of animal gene trees

More...
TreeFami
TF337005

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096, zf-C2H2, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355, ZnF_C2H2, 14 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667, SSF57667, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6ZNH5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESPRGWTLQ VAPEEGQVLC NVKTATRGLS EGAVSGGWGA WENSTEVPRE
60 70 80 90 100
AGDGQRQQAT LGAADEQGGP GRELGPADGG RDGAGPRSEP ADRALRPSPL
110 120 130 140 150
PEEPGCRCGE CGKAFSQGSY LLQHRRVHTG EKPYTCPECG KAFAWSSNLS
160 170 180 190 200
QHQRIHSGEK PYACRECGKA FRAHSQLIHH QETHSGLKPF RCPDCGKSFG
210 220 230 240 250
RSTTLVQHRR THTGEKPYEC PECGKAFSWN SNFLEHRRVH TGARPHACRD
260 270 280 290 300
CGKAFSQSSN LAEHLKIHAG ARPHACPDCG KAFVRVAGLR QHRRTHSSEK
310 320 330 340 350
PFPCAECGKA FRESSQLLQH QRTHTGERPF ECAECGQAFV MGSYLAEHRR
360 370 380 390 400
VHTGEKPHAC AQCGKAFSQR SNLLSHRRTH SGAKPFACAD CGKAFRGSSG
410 420 430 440 450
LAHHRLSHTG ERPFACAECG KAFRGSSELR QHQRLHSGER PFVCAHCSKA
460 470 480 490
FVRKSELLSH RRTHTGERPY ACGECGKPFS HRCNLNEHQK RHGGRAAP
Length:498
Mass (Da):54,721
Last modified:May 5, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAC4DD81A06CECFA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M0R159M0R159_HUMAN
Zinc finger protein 497
ZNF497
108Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti212 – 214HTG → RA in AAF16412 (Ref. 4) Curated3
Sequence conflicti241T → A in AAF16412 (Ref. 4) Curated1
Sequence conflicti320H → Y in AAF16412 (Ref. 4) Curated1
Sequence conflicti367F → S in BAC86660 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_055270174H → Q2 PublicationsCorresponds to variant dbSNP:rs12609654Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK126727 mRNA Translation: BAC86660.1
AK131209 mRNA Translation: BAD18400.1
CH471135 Genomic DNA Translation: EAW72578.1
BC118983 mRNA Translation: AAI18984.1
BC125273 mRNA Translation: AAI25274.1
AF064790 Genomic DNA Translation: AAF16412.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12977.1

NCBI Reference Sequences

More...
RefSeqi
NP_001193938.1, NM_001207009.1
NP_940860.2, NM_198458.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000311044; ENSP00000311183; ENSG00000174586
ENST00000425453; ENSP00000402815; ENSG00000174586

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
162968

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:162968

UCSC genome browser

More...
UCSCi
uc002qsh.3, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK126727 mRNA Translation: BAC86660.1
AK131209 mRNA Translation: BAD18400.1
CH471135 Genomic DNA Translation: EAW72578.1
BC118983 mRNA Translation: AAI18984.1
BC125273 mRNA Translation: AAI25274.1
AF064790 Genomic DNA Translation: AAF16412.1
CCDSiCCDS12977.1
RefSeqiNP_001193938.1, NM_001207009.1
NP_940860.2, NM_198458.2

3D structure databases

SMRiQ6ZNH5
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127835, 41 interactors
IntActiQ6ZNH5, 35 interactors
STRINGi9606.ENSP00000311183

PTM databases

iPTMnetiQ6ZNH5
PhosphoSitePlusiQ6ZNH5

Polymorphism and mutation databases

BioMutaiZNF497
DMDMi229462815

Proteomic databases

jPOSTiQ6ZNH5
MassIVEiQ6ZNH5
PaxDbiQ6ZNH5
PeptideAtlasiQ6ZNH5
PRIDEiQ6ZNH5
ProteomicsDBi68026

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
19686, 34 antibodies

Genome annotation databases

EnsembliENST00000311044; ENSP00000311183; ENSG00000174586
ENST00000425453; ENSP00000402815; ENSG00000174586
GeneIDi162968
KEGGihsa:162968
UCSCiuc002qsh.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
162968
EuPathDBiHostDB:ENSG00000174586.10

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF497
HGNCiHGNC:23714, ZNF497
HPAiENSG00000174586, Low tissue specificity
neXtProtiNX_Q6ZNH5
OpenTargetsiENSG00000174586
PharmGKBiPA134994387

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000165876
HOGENOMiCLU_002678_44_0_1
InParanoidiQ6ZNH5
OMAiQMAPKEG
OrthoDBi1318335at2759
PhylomeDBiQ6ZNH5
TreeFamiTF337005

Enzyme and pathway databases

PathwayCommonsiQ6ZNH5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
162968, 6 hits in 896 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
162968
PharosiQ6ZNH5, Tdark

Protein Ontology

More...
PROi
PR:Q6ZNH5
RNActiQ6ZNH5, protein

Gene expression databases

BgeeiENSG00000174586, Expressed in right uterine tube and 113 other tissues
ExpressionAtlasiQ6ZNH5, baseline and differential
GenevisibleiQ6ZNH5, HS

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 13 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 14 hits
SUPFAMiSSF57667, SSF57667, 8 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 14 hits
PS50157, ZINC_FINGER_C2H2_2, 14 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN497_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZNH5
Secondary accession number(s): Q05AG8
, Q0VF48, Q6ZTD2, Q9UIA8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 5, 2009
Last modified: October 7, 2020
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. SIMILARITY comments
    Index of protein domains and families
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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