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Entry version 145 (17 Jun 2020)
Sequence version 2 (18 May 2010)
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Protein

Zinc finger protein 600

Gene

ZNF600

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri162 – 184C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri190 – 212C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri218 – 240C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 11; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 20PROSITE-ProRule annotationAdd BLAST23

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-212436 Generic Transcription Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 600
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF600
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000189190.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:30951 ZNF600

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6ZNG1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
162966

Open Targets

More...
OpenTargetsi
ENSG00000189190

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134977938

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6ZNG1 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ZNF600

Domain mapping of disease mutations (DMDM)

More...
DMDMi
296453048

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002345931 – 722Zinc finger protein 600Add BLAST722

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6ZNG1

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6ZNG1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6ZNG1

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6ZNG1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6ZNG1

PeptideAtlas

More...
PeptideAtlasi
Q6ZNG1

PRoteomics IDEntifications database

More...
PRIDEi
Q6ZNG1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
68023

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6ZNG1

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6ZNG1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000189190 Expressed in tendon and 192 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6ZNG1 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6ZNG1 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000189190 Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
127833, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q6ZNG1, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000344791

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6ZNG1 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6ZNG1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri162 – 184C2H2-type 1; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri190 – 212C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri218 – 240C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri246 – 268C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri274 – 296C2H2-type 5PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri302 – 324C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri330 – 352C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri358 – 380C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri386 – 408C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri414 – 436C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri442 – 464C2H2-type 11; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri470 – 492C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri498 – 520C2H2-type 13PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri526 – 548C2H2-type 14PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri554 – 576C2H2-type 15PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri582 – 604C2H2-type 16PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri610 – 632C2H2-type 17PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri638 – 660C2H2-type 18PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri666 – 688C2H2-type 19PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri694 – 716C2H2-type 20PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1721 Eukaryota
COG5048 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164431

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002678_17_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6ZNG1

KEGG Orthology (KO)

More...
KOi
K09228

Identification of Orthologs from Complete Genome Data

More...
OMAi
KQYLTCH

Database of Orthologous Groups

More...
OrthoDBi
925064at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6ZNG1

TreeFam database of animal gene trees

More...
TreeFami
TF341892

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 13 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 19 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 11 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 18 hits
PS50157 ZINC_FINGER_C2H2_2, 20 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q6ZNG1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMKEVLSTGQ GNTEVIHTGT LQRYQSYHIG DFCFQEIEKE IHDIEFQCQE
60 70 80 90 100
DERNGHEAPM TKIKKLTGST DQHDHRHAGN KPIKDQLGSS FYSHLPELHI
110 120 130 140 150
IQIKGKIGNQ FEKSTSDAPS VSTSQRISPR PQIHISNNYG NNSPNSSLLP
160 170 180 190 200
QKQEVYMREK SFQCNESGKA FNCSSLLRKH QIPHLGDKQY KCDVCGKLFN
210 220 230 240 250
HKQYLTCHCR CHTGEKPYKC NECGKSFSQV SSLTCHRRLH TAVKSHKCNE
260 270 280 290 300
CGKIFGQNSA LVIHKAIHTG EKPYKCNECD KAFNQQSNLA RHRRIHTGEK
310 320 330 340 350
PYKCEECDKV FSRKSTLESH KRIHTGEKPY KCKVCDTAFT WNSQLARHKR
360 370 380 390 400
IHTGEKTYKC NECGKTFSHK SSLVCHHRLH GGEKSYKCKV CDKAFAWNSH
410 420 430 440 450
LVRHTRIHSG GKPYKCNECG KTFGQNSDLL IHKSIHTGEQ PYKYEECEKV
460 470 480 490 500
FSCGSTLETH KIIHTGEKPY KCKVCDKAFA CHSYLAKHTR IHSGEKPYKC
510 520 530 540 550
NECSKTFRLR SYLASHRRVH SGEKPYKCNE CSKTFSQRSY LHCHRRLHSG
560 570 580 590 600
EKPYKCNECG KTFSHKPSLV HHRRLHTGEK SYKCTVCDKA FVRNSYLARH
610 620 630 640 650
TRIHTAEKPY KCNECGKAFN QQSQLSLHHR IHAGEKLYKC ETCDKVFSRK
660 670 680 690 700
SHLKRHRRIH PGKKPYKCKV CDKTFGSDSH LKQHTGLHTG EKPYKCNECG
710 720
KAFSKQSTLI HHQAVHGVGK LD
Length:722
Mass (Da):83,124
Last modified:May 18, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE316D2E12AFB59F9
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3B3IT03A0A3B3IT03_HUMAN
Zinc finger protein 600
ZNF600 hCG_2044038
791Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ITH4A0A3B3ITH4_HUMAN
Zinc finger protein 600
ZNF600
204Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3B3ITY9A0A3B3ITY9_HUMAN
Zinc finger protein 600
ZNF600
210Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti508R → H in BAD18414 (PubMed:14702039).Curated1
Sequence conflicti631I → V in CAE45968 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0574272M → V. Corresponds to variant dbSNP:rs7252818Ensembl.1
Natural variantiVAR_05992513T → R. Corresponds to variant dbSNP:rs7252128Ensembl.1
Natural variantiVAR_059926209C → R2 PublicationsCorresponds to variant dbSNP:rs1820128Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK131231 mRNA Translation: BAD18414.1
BX640933 mRNA Translation: CAE45968.1
AC008813 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12856.1

NCBI Reference Sequences

More...
RefSeqi
NP_001308795.1, NM_001321866.1
NP_001308796.1, NM_001321867.1
NP_940859.3, NM_198457.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000338230; ENSP00000344791; ENSG00000189190

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
162966

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:162966

UCSC genome browser

More...
UCSCi
uc002qab.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK131231 mRNA Translation: BAD18414.1
BX640933 mRNA Translation: CAE45968.1
AC008813 Genomic DNA No translation available.
CCDSiCCDS12856.1
RefSeqiNP_001308795.1, NM_001321866.1
NP_001308796.1, NM_001321867.1
NP_940859.3, NM_198457.3

3D structure databases

SMRiQ6ZNG1
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi127833, 1 interactor
IntActiQ6ZNG1, 2 interactors
STRINGi9606.ENSP00000344791

PTM databases

iPTMnetiQ6ZNG1
PhosphoSitePlusiQ6ZNG1

Polymorphism and mutation databases

BioMutaiZNF600
DMDMi296453048

Proteomic databases

EPDiQ6ZNG1
jPOSTiQ6ZNG1
MassIVEiQ6ZNG1
MaxQBiQ6ZNG1
PaxDbiQ6ZNG1
PeptideAtlasiQ6ZNG1
PRIDEiQ6ZNG1
ProteomicsDBi68023

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
56950 35 antibodies

Genome annotation databases

EnsembliENST00000338230; ENSP00000344791; ENSG00000189190
GeneIDi162966
KEGGihsa:162966
UCSCiuc002qab.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
162966
DisGeNETi162966
EuPathDBiHostDB:ENSG00000189190.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ZNF600
HGNCiHGNC:30951 ZNF600
HPAiENSG00000189190 Low tissue specificity
neXtProtiNX_Q6ZNG1
OpenTargetsiENSG00000189190
PharmGKBiPA134977938

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
GeneTreeiENSGT00940000164431
HOGENOMiCLU_002678_17_0_1
InParanoidiQ6ZNG1
KOiK09228
OMAiKQYLTCH
OrthoDBi925064at2759
PhylomeDBiQ6ZNG1
TreeFamiTF341892

Enzyme and pathway databases

ReactomeiR-HSA-212436 Generic Transcription Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
162966 1 hit in 805 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
162966
PharosiQ6ZNG1 Tdark

Protein Ontology

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PROi
PR:Q6ZNG1
RNActiQ6ZNG1 protein

Gene expression databases

BgeeiENSG00000189190 Expressed in tendon and 192 other tissues
ExpressionAtlasiQ6ZNG1 baseline and differential
GenevisibleiQ6ZNG1 HS

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 13 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 19 hits
SUPFAMiSSF57667 SSF57667, 11 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 18 hits
PS50157 ZINC_FINGER_C2H2_2, 20 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN600_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZNG1
Secondary accession number(s): Q6MZR0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 18, 2010
Last modified: June 17, 2020
This is version 145 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
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