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Entry version 113 (11 Dec 2019)
Sequence version 1 (05 Jul 2004)
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Protein

Alkylglycerol monooxygenase

Gene

AGMO

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids. Ether lipids are essential components of brain membranes.1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Fe cation1 Publication

<p>This subsection of the ‘Function’ section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=11 µM for 1-O pyrenedecyl glycerol (in presence of ALDH3A2)1 Publication
  2. KM=2.58 µM for tetrahydrobiopterin (in presence of ALDH3A2)1 Publication

    <p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

    GO - Biological processi

    <p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

    Molecular functionOxidoreductase
    LigandIron

    Enzyme and pathway databases

    Reactome - a knowledgebase of biological pathways and processes

    More...
    Reactomei
    R-HSA-75109 Triglyceride biosynthesis

    Chemistry databases

    SwissLipids knowledge resource for lipid biology

    More...
    SwissLipidsi
    SLP:000000633

    <p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
    Recommended name:
    Alkylglycerol monooxygenase (EC:1.14.16.51 Publication)
    Alternative name(s):
    Transmembrane protein 195
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
    Name:AGMO
    Synonyms:TMEM195
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
    • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

    Organism-specific databases

    Eukaryotic Pathogen Database Resources

    More...
    EuPathDBi
    HostDB:ENSG00000187546.13

    Human Gene Nomenclature Database

    More...
    HGNCi
    HGNC:33784 AGMO

    Online Mendelian Inheritance in Man (OMIM)

    More...
    MIMi
    613738 gene

    neXtProt; the human protein knowledge platform

    More...
    neXtProti
    NX_Q6ZNB7

    <p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

    Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

    Topology

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei43 – 63HelicalSequence analysisAdd BLAST21
    Transmembranei111 – 131HelicalSequence analysisAdd BLAST21
    Transmembranei334 – 354HelicalSequence analysisAdd BLAST21
    Transmembranei363 – 383HelicalSequence analysisAdd BLAST21
    Transmembranei413 – 433HelicalSequence analysisAdd BLAST21

    Keywords - Cellular componenti

    Endoplasmic reticulum, Membrane

    <p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi132H → A: Loss of function; when associated with A-136; A-145; A-148; A-149; A-221; A-224 and A-225. 1 Publication1
    Mutagenesisi136H → A: Loss of function; when associated with A-132; A-145; A-148; A-149; A-221; A-224 and A-225. 1 Publication1
    Mutagenesisi145H → A: Loss of function; when associated with A-132; A-136; A-148; A-149; A-221; A-224 and A-225. 1 Publication1
    Mutagenesisi148H → A: Loss of function; when associated with A-132; A-136; A-145; A-149; A-221; A-224 and A-225. 1 Publication1
    Mutagenesisi149H → A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-221; A-224 and A-225. 1 Publication1
    Mutagenesisi221H → A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-224 and A-225. 1 Publication1
    Mutagenesisi224H → A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-221 and A-225. 1 Publication1
    Mutagenesisi225H → A: Loss of function; when associated with A-132; A-136; A-145; A-148; A-149; A-221 and A-224. 1 Publication1

    Organism-specific databases

    DisGeNET

    More...
    DisGeNETi
    392636

    Open Targets

    More...
    OpenTargetsi
    ENSG00000187546

    The Pharmacogenetics and Pharmacogenomics Knowledge Base

    More...
    PharmGKBi
    PA162406334

    Miscellaneous databases

    Pharos NIH Druggable Genome Knowledgebase

    More...
    Pharosi
    Q6ZNB7 Tbio

    Polymorphism and mutation databases

    BioMuta curated single-nucleotide variation and disease association database

    More...
    BioMutai
    AGMO

    Domain mapping of disease mutations (DMDM)

    More...
    DMDMi
    74710656

    <p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

    Molecule processing

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002993001 – 445Alkylglycerol monooxygenaseAdd BLAST445

    Proteomic databases

    MassIVE - Mass Spectrometry Interactive Virtual Environment

    More...
    MassIVEi
    Q6ZNB7

    PaxDb, a database of protein abundance averages across all three domains of life

    More...
    PaxDbi
    Q6ZNB7

    PeptideAtlas

    More...
    PeptideAtlasi
    Q6ZNB7

    PRoteomics IDEntifications database

    More...
    PRIDEi
    Q6ZNB7

    ProteomicsDB: a multi-organism proteome resource

    More...
    ProteomicsDBi
    68010

    Consortium for Top Down Proteomics

    More...
    TopDownProteomicsi
    Q6ZNB7

    PTM databases

    iPTMnet integrated resource for PTMs in systems biology context

    More...
    iPTMneti
    Q6ZNB7

    Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

    More...
    PhosphoSitePlusi
    Q6ZNB7

    <p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

    Gene expression databases

    Bgee dataBase for Gene Expression Evolution

    More...
    Bgeei
    ENSG00000187546 Expressed in 77 organ(s), highest expression level in liver

    ExpressionAtlas, Differential and Baseline Expression

    More...
    ExpressionAtlasi
    Q6ZNB7 baseline and differential

    Organism-specific databases

    Human Protein Atlas

    More...
    HPAi
    HPA057900

    <p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

    Protein-protein interaction databases

    Protein interaction database and analysis system

    More...
    IntActi
    Q6ZNB7, 1 interactor

    STRING: functional protein association networks

    More...
    STRINGi
    9606.ENSP00000341662

    Miscellaneous databases

    RNAct, Protein-RNA interaction predictions for model organisms.

    More...
    RNActi
    Q6ZNB7 protein

    <p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini120 – 249Fatty acid hydroxylaseSequence analysisAdd BLAST130

    Motif

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi132 – 136Histidine box-15
    Motifi145 – 149Histidine box-25
    Motifi221 – 225Histidine box-35

    <p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    evolutionary genealogy of genes: Non-supervised Orthologous Groups

    More...
    eggNOGi
    KOG0872 Eukaryota
    COG3000 LUCA

    Ensembl GeneTree

    More...
    GeneTreei
    ENSGT00440000033807

    InParanoid: Eukaryotic Ortholog Groups

    More...
    InParanoidi
    Q6ZNB7

    KEGG Orthology (KO)

    More...
    KOi
    K15537

    Identification of Orthologs from Complete Genome Data

    More...
    OMAi
    FMPTGWR

    Database of Orthologous Groups

    More...
    OrthoDBi
    1446475at2759

    Database for complete collections of gene phylogenies

    More...
    PhylomeDBi
    Q6ZNB7

    TreeFam database of animal gene trees

    More...
    TreeFami
    TF314881

    Family and domain databases

    Integrated resource of protein families, domains and functional sites

    More...
    InterProi
    View protein in InterPro
    IPR006694 Fatty_acid_hydroxylase

    Pfam protein domain database

    More...
    Pfami
    View protein in Pfam
    PF04116 FA_hydroxylase, 1 hit

    <p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

    <p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

    This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

    Q6ZNB7-1 [UniParc]FASTAAdd to basket
    « Hide
            10         20         30         40         50
    MKNPEAQQDV SVSQGFRMLF YTMKPSETSF QTLEEVPDYV KKATPFFISL
    60 70 80 90 100
    MLLELVVSWI LKGKPPGRLD DALTSISAGV LSRLPSLFFR SIELTSYIYI
    110 120 130 140 150
    WENYRLFNLP WDSPWTWYSA FLGVDFGYYW FHRMAHEVNI MWAGHQTHHS
    160 170 180 190 200
    SEDYNLSTAL RQSVLQIYTS WIFYSPLALF IPPSVYAVHL QFNLLYQFWI
    210 220 230 240 250
    HTEVINNLGP LELILNTPSH HRVHHGRNRY CIDKNYAGVL IIWDKIFGTF
    260 270 280 290 300
    EAENEKVVYG LTHPINTFEP IKVQFHHLFS IWTTFWATPG FFNKFSVIFK
    310 320 330 340 350
    GPGWGPGKPR LGLSEEIPEV TGKEVPFSSS SSQLLKIYTV VQFALMLAFY
    360 370 380 390 400
    EETFADTAAL SQVTLLLRVC FIILTLTSIG FLLDQRPKAA IMETLRCLMF
    410 420 430 440
    LMLYRFGHLK PLVPSLSSAF EIVFSICIAF WGVRSMKQLT SHPWK
    Length:445
    Mass (Da):51,500
    Last modified:July 5, 2004 - v1
    <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD6C8705DF1A8E043
    GO

    <p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

    There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
    EntryEntry nameProtein names
    Gene namesLengthAnnotation
    H7C0E0H7C0E0_HUMAN
    Alkylglycerol monooxygenase
    AGMO
    74Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
    H0Y3V1H0Y3V1_HUMAN
    Alkylglycerol monooxygenase
    AGMO
    87Annotation score:

    Annotation score:1 out of 5

    <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

    <p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

    The sequence EAL24290 differs from that shown. Reason: Erroneous gene model prediction.Curated

    Natural variant

    Feature keyPosition(s)DescriptionActionsGraphical viewLength
    <p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_062201279F → L. Corresponds to variant dbSNP:rs58564185Ensembl.1
    Natural variantiVAR_062202280S → Y. Corresponds to variant dbSNP:rs59160822Ensembl.1

    Sequence databases

    Select the link destinations:

    EMBL nucleotide sequence database

    More...
    EMBLi

    GenBank nucleotide sequence database

    More...
    GenBanki

    DNA Data Bank of Japan; a nucleotide sequence database

    More...
    DDBJi
    Links Updated
    AK131284 mRNA Translation: BAD18458.1
    CH236948 Genomic DNA Translation: EAL24290.1 Sequence problems.
    BC108676 mRNA Translation: AAI08677.1

    The Consensus CDS (CCDS) project

    More...
    CCDSi
    CCDS34604.1

    NCBI Reference Sequences

    More...
    RefSeqi
    NP_001004320.1, NM_001004320.1

    Genome annotation databases

    Ensembl eukaryotic genome annotation project

    More...
    Ensembli
    ENST00000342526; ENSP00000341662; ENSG00000187546

    Database of genes from NCBI RefSeq genomes

    More...
    GeneIDi
    392636

    KEGG: Kyoto Encyclopedia of Genes and Genomes

    More...
    KEGGi
    hsa:392636

    Keywords - Coding sequence diversityi

    Polymorphism

    <p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

    <p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBLi
    GenBanki
    DDBJi
    Links Updated
    AK131284 mRNA Translation: BAD18458.1
    CH236948 Genomic DNA Translation: EAL24290.1 Sequence problems.
    BC108676 mRNA Translation: AAI08677.1
    CCDSiCCDS34604.1
    RefSeqiNP_001004320.1, NM_001004320.1

    3D structure databases

    Database of comparative protein structure models

    More...
    ModBasei
    Search...

    SWISS-MODEL Interactive Workspace

    More...
    SWISS-MODEL-Workspacei
    Submit a new modelling project...

    Protein-protein interaction databases

    IntActiQ6ZNB7, 1 interactor
    STRINGi9606.ENSP00000341662

    Chemistry databases

    SwissLipidsiSLP:000000633

    PTM databases

    iPTMnetiQ6ZNB7
    PhosphoSitePlusiQ6ZNB7

    Polymorphism and mutation databases

    BioMutaiAGMO
    DMDMi74710656

    Proteomic databases

    MassIVEiQ6ZNB7
    PaxDbiQ6ZNB7
    PeptideAtlasiQ6ZNB7
    PRIDEiQ6ZNB7
    ProteomicsDBi68010
    TopDownProteomicsiQ6ZNB7

    Genome annotation databases

    EnsembliENST00000342526; ENSP00000341662; ENSG00000187546
    GeneIDi392636
    KEGGihsa:392636

    Organism-specific databases

    Comparative Toxicogenomics Database

    More...
    CTDi
    392636
    DisGeNETi392636
    EuPathDBiHostDB:ENSG00000187546.13

    GeneCards: human genes, protein and diseases

    More...
    GeneCardsi
    AGMO
    HGNCiHGNC:33784 AGMO
    HPAiHPA057900
    MIMi613738 gene
    neXtProtiNX_Q6ZNB7
    OpenTargetsiENSG00000187546
    PharmGKBiPA162406334

    GenAtlas: human gene database

    More...
    GenAtlasi
    Search...

    Phylogenomic databases

    eggNOGiKOG0872 Eukaryota
    COG3000 LUCA
    GeneTreeiENSGT00440000033807
    InParanoidiQ6ZNB7
    KOiK15537
    OMAiFMPTGWR
    OrthoDBi1446475at2759
    PhylomeDBiQ6ZNB7
    TreeFamiTF314881

    Enzyme and pathway databases

    ReactomeiR-HSA-75109 Triglyceride biosynthesis

    Miscellaneous databases

    ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

    More...
    ChiTaRSi
    AGMO human

    Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

    More...
    GenomeRNAii
    392636
    PharosiQ6ZNB7 Tbio

    Protein Ontology

    More...
    PROi
    PR:Q6ZNB7
    RNActiQ6ZNB7 protein

    The Stanford Online Universal Resource for Clones and ESTs

    More...
    SOURCEi
    Search...

    Gene expression databases

    BgeeiENSG00000187546 Expressed in 77 organ(s), highest expression level in liver
    ExpressionAtlasiQ6ZNB7 baseline and differential

    Family and domain databases

    InterProiView protein in InterPro
    IPR006694 Fatty_acid_hydroxylase
    PfamiView protein in Pfam
    PF04116 FA_hydroxylase, 1 hit

    ProtoNet; Automatic hierarchical classification of proteins

    More...
    ProtoNeti
    Search...

    MobiDB: a database of protein disorder and mobility annotations

    More...
    MobiDBi
    Search...

    <p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

    <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiALKMO_HUMAN
    <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6ZNB7
    Secondary accession number(s): A4D114, A6NCH5
    <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: July 5, 2004
    Last modified: December 11, 2019
    This is version 113 of the entry and version 1 of the sequence. See complete history.
    <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    <p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

    Keywords - Technical termi

    Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Human chromosome 7
      Human chromosome 7: entries, gene names and cross-references to MIM
    3. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    4. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    5. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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