UniProtKB - Q6Z6S1 (API5_ORYSJ)
Protein
Apoptosis inhibitor 5-like protein API5
Gene
API5
Organism
Oryza sativa subsp. japonica (Rice)
Status
Functioni
Putative anti-apoptotic factor involved in the regulation of tapetal programmed cell death (PCD) and degeneration during anther development. Interacts directly with the DEAD-box ATP-dependent RNA helicases AIP1 and AIP2 that form dimers and bind the promoter region of the cysteine protease CP1 involved in tapetum PCD.1 Publication
GO - Molecular functioni
- mRNA binding Source: GO_Central
- RNA binding Source: GO_Central
GO - Biological processi
- pollen development Source: UniProtKB
- regulation of programmed cell death Source: UniProtKB
Keywordsi
Molecular function | Developmental protein |
Biological process | Apoptosis |
Names & Taxonomyi
Protein namesi | Recommended name: Apoptosis inhibitor 5-like protein API5Alternative name(s): Protein APOPTOSIS INHIBITOR 51 Publication |
Gene namesi | Name:API51 Publication Ordered Locus Names:Os02g0313400Imported, LOC_Os02g20930Curated ORF Names:OsJ_06432Imported, P0705A04.11Imported |
Organismi | Oryza sativa subsp. japonica (Rice) |
Taxonomic identifieri | 39947 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Oryzoideae › Oryzeae › Oryzinae › Oryza › Oryza sativa |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Nucleus
- nucleus Source: UniProtKB
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
Male sterility due to lack of tapetal programmed cell death (PCD) and degeneration, leading to defects in formation of male gametophytes.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000436460 | 1 – 537 | Apoptosis inhibitor 5-like protein API5Add BLAST | 537 |
Proteomic databases
PRIDEi | Q6Z6S1 |
Expressioni
Developmental stagei
During anther development, expressed in tapetal cells, parietal anther wall layers and microsporocytes from late stages 8 to stage 10.1 Publication
Interactioni
Subunit structurei
Interacts with AIP1 and AIP2.
1 PublicationProtein-protein interaction databases
STRINGi | 4530.OS02T0313400-01 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 9 – 363 | ARM-like and Heat-like helical repeatsCuratedAdd BLAST | 355 |
Sequence similaritiesi
Belongs to the API5 family.Curated
Phylogenomic databases
eggNOGi | KOG2213, Eukaryota |
InParanoidi | Q6Z6S1 |
OMAi | MEVQREG |
OrthoDBi | 1385954at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR008383, API5 IPR016024, ARM-type_fold |
PANTHERi | PTHR12758, PTHR12758, 1 hit |
Pfami | View protein in Pfam PF05918, API5, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6Z6S1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAASDADAAE VERLYELGER LSSAKDKSQH AADYEAIISA VKGQSVKAKQ
60 70 80 90 100
LAAQLIPRFF RSFPALAPRA MEAMFDLVDM EELATRIQAI RGFPLLAKDA
110 120 130 140 150
EFVSKIADIL GQLLASEENV ERDAVHKALM SLIRQDVKSS LQPLFKHVES
160 170 180 190 200
GSEIREKVIC FLKDKVFPVK AELLKPQAEM ERYITDLIKK SVLDVTGLEF
210 220 230 240 250
KLFMDFLRSL SIFGDSAPRE SFQELIEIIQ AQADLDAQFN VSDIDHIERW
260 270 280 290 300
TSCMYMALPI FMRGGSSSKF LNYFVKQIVP VFDKIPEEKK LDLLKTVAAS
310 320 330 340 350
SPYATAQDAR QLLPPVVQLL KKYMPGKKVE DINHNYVECL MYIFHHLAHK
360 370 380 390 400
TPNTTNSLCG YKIVTGQPSD RLGEDFSEHY KDFTERLTGT EETVRAVSKR
410 420 430 440 450
LTQGMADFNK AISSAKTEEE KTKIKSDQQK STMTMRAYNN ILAMAQPLRA
460 470 480 490 500
KSPLFIGDKK ITLSWMEQPK KPAPTTTGGK RSQPATNGNT PASKKGRGEG
510 520 530
AARNQLVNRA FEGLSRGGRG SGRGRGRGGR GRGWGYR
Sequence cautioni
The sequence BAF08570 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence BAS78330 differs from that shown. Reason: Erroneous gene model prediction.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP004891 Genomic DNA Translation: BAD15974.1 AP008208 Genomic DNA Translation: BAF08570.1 Sequence problems. AP014958 Genomic DNA Translation: BAS78330.1 Sequence problems. CM000139 Genomic DNA Translation: EAZ22757.1 |
RefSeqi | XP_015627484.1, XM_015771998.1 |
Genome annotation databases
GeneIDi | 4329135 |
KEGGi | osa:4329135 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AP004891 Genomic DNA Translation: BAD15974.1 AP008208 Genomic DNA Translation: BAF08570.1 Sequence problems. AP014958 Genomic DNA Translation: BAS78330.1 Sequence problems. CM000139 Genomic DNA Translation: EAZ22757.1 |
RefSeqi | XP_015627484.1, XM_015771998.1 |
3D structure databases
SMRi | Q6Z6S1 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4530.OS02T0313400-01 |
Proteomic databases
PRIDEi | Q6Z6S1 |
Genome annotation databases
GeneIDi | 4329135 |
KEGGi | osa:4329135 |
Phylogenomic databases
eggNOGi | KOG2213, Eukaryota |
InParanoidi | Q6Z6S1 |
OMAi | MEVQREG |
OrthoDBi | 1385954at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR008383, API5 IPR016024, ARM-type_fold |
PANTHERi | PTHR12758, PTHR12758, 1 hit |
Pfami | View protein in Pfam PF05918, API5, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | API5_ORYSJ | |
Accessioni | Q6Z6S1Primary (citable) accession number: Q6Z6S1 Secondary accession number(s): Q0E1R8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 8, 2016 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 100 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Oryza sativa (rice)
Index of Oryza sativa entries and their corresponding gene designations - SIMILARITY comments
Index of protein domains and families