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Entry version 94 (11 Dec 2019)
Sequence version 2 (11 Sep 2007)
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Protein

Auxin response factor 5

Gene

ARF5

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi148 – 250TF-B3PROSITE-ProRule annotationAdd BLAST103

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processAuxin signaling pathway, Transcription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Auxin response factor 5
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ARF5
Ordered Locus Names:Os02g0141100, LOC_Os02g04810
ORF Names:OJ1679_B08.29, OsJ_005181
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryza sativa subsp. japonica (Rice)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39947 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000059680 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002992581 – 1142Auxin response factor 5Add BLAST1142

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6Z2W3

PRoteomics IDEntifications database

More...
PRIDEi
Q6Z2W3

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, culms, leaves and young panicles.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Down-regulated by auxin under light condition.1 Publication

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6Z2W3 OS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimers and heterodimers.

By similarity

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
4530.OS02T0141100-00

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6Z2W3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1009 – 1093PB1PROSITE-ProRule annotationAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi427 – 730Gln-richAdd BLAST304

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Interactions between auxin response factors (ARFs) and Aux/IAA proteins occur through their C-terminal dimerization domains III and IV.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ARF family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHYA Eukaryota
ENOG410YDIT LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000241141

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6Z2W3

Database of Orthologous Groups

More...
OrthoDBi
116399at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd10017 B3_DNA, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.330.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR033389 AUX/IAA_dom
IPR010525 Auxin_resp
IPR003340 B3_DNA-bd
IPR015300 DNA-bd_pseudobarrel_sf
IPR000270 PB1_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02309 AUX_IAA, 1 hit
PF06507 Auxin_resp, 1 hit
PF02362 B3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01019 B3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101936 SSF101936, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50863 B3, 1 hit
PS51745 PB1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6Z2W3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASMKQQQTP ASSAVTAAAA ASSSATAAVA ACEGERKAAA INSELWHACA
60 70 80 90 100
GPLVSLPPVG SLVVYFPQGH SEQVAASMQK DVDAHVPSYP NLPSKLICLL
110 120 130 140 150
HGVNLHADPD TDEVYAQMTL QPVNTYGKEA LQISELALKQ ARPQMEFFCK
160 170 180 190 200
TLTASDTSTH GGFSVPRRAA EKIFPPLDFS MQPPAQELQA RDIHDNVWTF
210 220 230 240 250
RHIYRGQPKR HLLTTGWSLF VSGKRLFAGD SVIVVRDEKH QLLLGIRRAN
260 270 280 290 300
RQPTNISSSV LSSDSMHIGV LAAAAHAAAN SSPFTIFYNP RASPTEFVIP
310 320 330 340 350
FAKYQKALYS NQISLGMRFR MMFETEELGT RRYMGTITGI SDLDPVRWKN
360 370 380 390 400
SQWRNLQVGW DESAAGERRN RVSIWEIEPV AAPFFLCPQP FFGVKRPRQL
410 420 430 440 450
DDESEMENLF KRAMPWLGEE VCIKDTQNQN STAPGLSLVQ WMNMNRQQSS
460 470 480 490 500
SLANTAAQSE YLQALGNPAM QNLAADELAR QLYVQNNLLQ QNCIQFNSPK
510 520 530 540 550
LPQQMQTMND LSKAAIPLNQ LGAIINPQDQ KQDAVNHQRQ QNSIQVIPLS
560 570 580 590 600
QAQSNLVQAQ VIVQNQMQQQ KPSPTQNPQR INGQRLLLSH QQKDQNLQLQ
610 620 630 640 650
QQLLLQQKQQ LQQQQQQQQQ NQQQLNKSLG QLVNLASQQS KLFDEELQLQ
660 670 680 690 700
ILQKLQQQSL MSQSTSTLSQ PPLIQEQQKL ITDMQKQLSN SHSLAQQQMM
710 720 730 740 750
PQQEIKPSLQ ATPLLPTVQQ EQQQKLLQKQ VSLADVSGVA FQPISSTNVI
760 770 780 790 800
PKTGGAMIIS GATQSVVTEE MPSCSTSPST ANGNHFTQST KNRHCINTER
810 820 830 840 850
LPPSTAPMLI PTSIDAVTAT PLMTKELPKP NNNVKQSVVN SKLPNVAPGP
860 870 880 890 900
QNCINHALQT DNLETSSSAT SLCPSRTDGL VHQGFPSSNF NQHQMFKDAL
910 920 930 940 950
PDVEMEGVDP SNSGLFGINN DNLLGFPIET EDLLINALDS VKYQNHISTD
960 970 980 990 1000
VENNYPMQKD ALQEISTSMV SQSFGQSDMA FNSIDSAIND GAFLNKNSWP
1010 1020 1030 1040 1050
AAPLLQRMRT FTKVYKRGAV GRSIDIGRYS GYEELKHALA RMFGIEGQLE
1060 1070 1080 1090 1100
DRQRIGWKLV YKDHEDDILL LGDDPWEEFV NCVRCIRILS PQEVQQMSLD
1110 1120 1130 1140
GDLGSNVLPN QACSSSDGVN GWRPRCDQNP GNPSIGPYDQ FE
Length:1,142
Mass (Da):126,760
Last modified:September 11, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4C10FD37F01D4953
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0P0VEL8A0A0P0VEL8_ORYSJ
Auxin response factor
Os02g0141100, OSNPB_020141100
1,116Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD10267 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAF07771 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP005294 Genomic DNA Translation: BAD10267.1 Different initiation.
AP008208 Genomic DNA Translation: BAF07771.2 Sequence problems.
AP014958 Genomic DNA No translation available.
CM000139 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_015627049.1, XM_015771563.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4328265

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
osa:4328265

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP005294 Genomic DNA Translation: BAD10267.1 Different initiation.
AP008208 Genomic DNA Translation: BAF07771.2 Sequence problems.
AP014958 Genomic DNA No translation available.
CM000139 Genomic DNA No translation available.
RefSeqiXP_015627049.1, XM_015771563.1

3D structure databases

SMRiQ6Z2W3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi4530.OS02T0141100-00

Proteomic databases

PaxDbiQ6Z2W3
PRIDEiQ6Z2W3

Genome annotation databases

GeneIDi4328265
KEGGiosa:4328265

Phylogenomic databases

eggNOGiENOG410IHYA Eukaryota
ENOG410YDIT LUCA
HOGENOMiHOG000241141
InParanoidiQ6Z2W3
OrthoDBi116399at2759

Gene expression databases

GenevisibleiQ6Z2W3 OS

Family and domain databases

CDDicd10017 B3_DNA, 1 hit
Gene3Di2.40.330.10, 1 hit
InterProiView protein in InterPro
IPR033389 AUX/IAA_dom
IPR010525 Auxin_resp
IPR003340 B3_DNA-bd
IPR015300 DNA-bd_pseudobarrel_sf
IPR000270 PB1_dom
PfamiView protein in Pfam
PF02309 AUX_IAA, 1 hit
PF06507 Auxin_resp, 1 hit
PF02362 B3, 1 hit
SMARTiView protein in SMART
SM01019 B3, 1 hit
SUPFAMiSSF101936 SSF101936, 1 hit
PROSITEiView protein in PROSITE
PS50863 B3, 1 hit
PS51745 PB1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiARFE_ORYSJ
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6Z2W3
Secondary accession number(s): A3A309, Q0E417
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: December 11, 2019
This is version 94 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
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