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Entry version 55 (28 Feb 2018)
Sequence version 1 (05 Jul 2004)
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Protein
Submitted name:

NADH dehydrogenase subunit 6

Gene

ND6

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
NADH dehydrogenase subunit 6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ND6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniMitochondrionImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

MitochondrionImported

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IYM9 Eukaryota
ENOG410YP23 LUCA

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q6XBD3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30 
MMYALFLLSV GLVMGFVGFS SKPSPIYGGL VL
Length:32
Mass (Da):3,395
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i98EAF7E7B91FA743
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei32Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY243877 Genomic DNA Translation: AAP72377.1
AY243878 Genomic DNA Translation: AAP72378.1
AY243879 Genomic DNA Translation: AAP72380.1
AY243880 Genomic DNA Translation: AAP72382.1
AY243881 Genomic DNA Translation: AAP72384.1
AY243882 Genomic DNA Translation: AAP72386.1
AY243883 Genomic DNA Translation: AAP72388.1
AY243884 Genomic DNA Translation: AAP72390.1
AY243886 Genomic DNA Translation: AAP72394.1
AY243887 Genomic DNA Translation: AAP72396.1
AY243888 Genomic DNA Translation: AAP72398.1
AY243889 Genomic DNA Translation: AAP72400.1
AY243890 Genomic DNA Translation: AAP72402.1
AY243891 Genomic DNA Translation: AAP72404.1
AY243892 Genomic DNA Translation: AAP72406.1
AY243893 Genomic DNA Translation: AAP72408.1
AY243894 Genomic DNA Translation: AAP72410.1
AY243895 Genomic DNA Translation: AAP72412.1
AY243896 Genomic DNA Translation: AAP72414.1
AY243897 Genomic DNA Translation: AAP72416.1
AY243898 Genomic DNA Translation: AAP72418.1
AY243899 Genomic DNA Translation: AAP72420.1
AY243900 Genomic DNA Translation: AAP72422.1
AY243901 Genomic DNA Translation: AAP72424.1
AY243902 Genomic DNA Translation: AAP72426.1
AY243903 Genomic DNA Translation: AAP72428.1
AY243904 Genomic DNA Translation: AAP72430.1
AY243905 Genomic DNA Translation: AAP72432.1
AY243906 Genomic DNA Translation: AAP72434.1
AY243907 Genomic DNA Translation: AAP72436.1
AY243908 Genomic DNA Translation: AAP72438.1
AY243909 Genomic DNA Translation: AAP72440.1
AY243910 Genomic DNA Translation: AAP72442.1
AY243911 Genomic DNA Translation: AAP72444.1
AY243912 Genomic DNA Translation: AAP72446.1
AY243913 Genomic DNA Translation: AAP72448.1
AY243914 Genomic DNA Translation: AAP72450.1
AY243915 Genomic DNA Translation: AAP72452.1
AY243916 Genomic DNA Translation: AAP72454.1
AY243917 Genomic DNA Translation: AAP72456.1
AY243918 Genomic DNA Translation: AAP72458.1
AY243919 Genomic DNA Translation: AAP72460.1
AY243920 Genomic DNA Translation: AAP72462.1
AY243921 Genomic DNA Translation: AAP72464.1
AY243922 Genomic DNA Translation: AAP72466.1
AY243923 Genomic DNA Translation: AAP72468.1
AY243924 Genomic DNA Translation: AAP72470.1
AY243925 Genomic DNA Translation: AAP72472.1
AY243926 Genomic DNA Translation: AAP72474.1
AY243927 Genomic DNA Translation: AAP72476.1
AY243928 Genomic DNA Translation: AAP72478.1
AY243929 Genomic DNA Translation: AAP72480.1
AY243930 Genomic DNA Translation: AAP72482.1
AY243931 Genomic DNA Translation: AAP72484.1
AY243932 Genomic DNA Translation: AAP72486.1
AY243933 Genomic DNA Translation: AAP72488.1
AY243934 Genomic DNA Translation: AAP72490.1
AY243935 Genomic DNA Translation: AAP72492.1
AY243936 Genomic DNA Translation: AAP72494.1
AY243937 Genomic DNA Translation: AAP72496.1
AY243938 Genomic DNA Translation: AAP72498.1
AY243939 Genomic DNA Translation: AAP72500.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY243877 Genomic DNA Translation: AAP72377.1
AY243878 Genomic DNA Translation: AAP72378.1
AY243879 Genomic DNA Translation: AAP72380.1
AY243880 Genomic DNA Translation: AAP72382.1
AY243881 Genomic DNA Translation: AAP72384.1
AY243882 Genomic DNA Translation: AAP72386.1
AY243883 Genomic DNA Translation: AAP72388.1
AY243884 Genomic DNA Translation: AAP72390.1
AY243886 Genomic DNA Translation: AAP72394.1
AY243887 Genomic DNA Translation: AAP72396.1
AY243888 Genomic DNA Translation: AAP72398.1
AY243889 Genomic DNA Translation: AAP72400.1
AY243890 Genomic DNA Translation: AAP72402.1
AY243891 Genomic DNA Translation: AAP72404.1
AY243892 Genomic DNA Translation: AAP72406.1
AY243893 Genomic DNA Translation: AAP72408.1
AY243894 Genomic DNA Translation: AAP72410.1
AY243895 Genomic DNA Translation: AAP72412.1
AY243896 Genomic DNA Translation: AAP72414.1
AY243897 Genomic DNA Translation: AAP72416.1
AY243898 Genomic DNA Translation: AAP72418.1
AY243899 Genomic DNA Translation: AAP72420.1
AY243900 Genomic DNA Translation: AAP72422.1
AY243901 Genomic DNA Translation: AAP72424.1
AY243902 Genomic DNA Translation: AAP72426.1
AY243903 Genomic DNA Translation: AAP72428.1
AY243904 Genomic DNA Translation: AAP72430.1
AY243905 Genomic DNA Translation: AAP72432.1
AY243906 Genomic DNA Translation: AAP72434.1
AY243907 Genomic DNA Translation: AAP72436.1
AY243908 Genomic DNA Translation: AAP72438.1
AY243909 Genomic DNA Translation: AAP72440.1
AY243910 Genomic DNA Translation: AAP72442.1
AY243911 Genomic DNA Translation: AAP72444.1
AY243912 Genomic DNA Translation: AAP72446.1
AY243913 Genomic DNA Translation: AAP72448.1
AY243914 Genomic DNA Translation: AAP72450.1
AY243915 Genomic DNA Translation: AAP72452.1
AY243916 Genomic DNA Translation: AAP72454.1
AY243917 Genomic DNA Translation: AAP72456.1
AY243918 Genomic DNA Translation: AAP72458.1
AY243919 Genomic DNA Translation: AAP72460.1
AY243920 Genomic DNA Translation: AAP72462.1
AY243921 Genomic DNA Translation: AAP72464.1
AY243922 Genomic DNA Translation: AAP72466.1
AY243923 Genomic DNA Translation: AAP72468.1
AY243924 Genomic DNA Translation: AAP72470.1
AY243925 Genomic DNA Translation: AAP72472.1
AY243926 Genomic DNA Translation: AAP72474.1
AY243927 Genomic DNA Translation: AAP72476.1
AY243928 Genomic DNA Translation: AAP72478.1
AY243929 Genomic DNA Translation: AAP72480.1
AY243930 Genomic DNA Translation: AAP72482.1
AY243931 Genomic DNA Translation: AAP72484.1
AY243932 Genomic DNA Translation: AAP72486.1
AY243933 Genomic DNA Translation: AAP72488.1
AY243934 Genomic DNA Translation: AAP72490.1
AY243935 Genomic DNA Translation: AAP72492.1
AY243936 Genomic DNA Translation: AAP72494.1
AY243937 Genomic DNA Translation: AAP72496.1
AY243938 Genomic DNA Translation: AAP72498.1
AY243939 Genomic DNA Translation: AAP72500.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410IYM9 Eukaryota
ENOG410YP23 LUCA

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
MT-ND6 human

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6XBD3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6XBD3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: February 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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