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Entry version 134 (16 Oct 2019)
Sequence version 1 (05 Jul 2004)
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Protein

E3 ubiquitin-protein ligase UPL3

Gene

UPL3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the repression of endoreduplication process and the cell morphogenesis in the trichomes.2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine. EC:2.3.2.26

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1855Glycyl thioester intermediatePROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase
Biological processUbl conjugation pathway

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
E3 ubiquitin-protein ligase UPL3 (EC:2.3.2.26)
Short name:
Ubiquitin-protein ligase 3
Alternative name(s):
HECT ubiquitin-protein ligase 3
HECT-type E3 ubiquitin transferase UPL3
Protein KAKTUS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:UPL3
Synonyms:KAK
Ordered Locus Names:At4g38600/At4g38610
ORF Names:F20M13.160/F20M13.170
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT4G38600

The Arabidopsis Information Resource

More...
TAIRi
locus:2121224 AT4G38600

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003120211 – 1888E3 ubiquitin-protein ligase UPL3Add BLAST1888

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6WWW4

PRoteomics IDEntifications database

More...
PRIDEi
Q6WWW4

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6WWW4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6WWW4 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6WWW4 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
15297, 2 interactors

STRING: functional protein association networks

More...
STRINGi
3702.AT4G38600.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati227 – 267ARM 1Add BLAST41
Repeati270 – 310ARM 2Add BLAST41
Repeati312 – 349ARM 3Add BLAST38
Repeati351 – 390ARM 4Add BLAST40
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1490 – 1888HECTPROSITE-ProRule annotationAdd BLAST399

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1377 – 1451K-boxAdd BLAST75

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi13 – 81Ser-richAdd BLAST69
Compositional biasi128 – 133Poly-Ala6
Compositional biasi1088 – 1136Asp-richAdd BLAST49
Compositional biasi1155 – 1160Poly-Ala6
Compositional biasi1181 – 1186Poly-Ala6
Compositional biasi1243 – 1248Poly-Asp6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPL family. K-HECT subfamily.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0168 Eukaryota
KOG0170 Eukaryota
COG5021 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000238707

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6WWW4

KEGG Orthology (KO)

More...
KOi
K10590

Identification of Orthologs from Complete Genome Data

More...
OMAi
HQESQAI

Database of Orthologous Groups

More...
OrthoDBi
34110at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6WWW4

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00078 HECTc, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00632 HECT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00185 ARM, 3 hits
SM00119 HECTc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit
SSF56204 SSF56204, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50237 HECT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6WWW4-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
METRSRKRAE ATSAAPSSSS SSPPPPPSAS GPTTRSKRAR LSSSSSSSLA
60 70 80 90 100
PTPPSSSTTT RSRSSRSAAA AAPMDTSTDS SGFRRGGRGN RGNNNDNSDK
110 120 130 140 150
GKEKEHDVRI RERERERDRA REQLNMDAAA AAARSADEDD DNDSEDGNGG
160 170 180 190 200
FMHPNMSSAS SALQGLLRKL GAGLDDLLPS SGIGSASSSH LNGRMKKILS
210 220 230 240 250
GLRAEGEEGK QVEALTQLCE MLSIGTEDSL STFSVDSFVP VLVGLLNHES
260 270 280 290 300
NPDIMLLAAR ALTHLCDVLP SSCAAVVHYG AVSCLVARLL TIEYMDLAEQ
310 320 330 340 350
SLQALKKISQ EHPTACLRAG ALMAVLSYLD FFSTGVQRVA LSTAANMCKK
360 370 380 390 400
LPSDASDYVM EAVPLLTNLL QYHDSKVLEY ASICLTRIAE AFAPYPEKLD
410 420 430 440 450
ELCNHGLVTQ AASLISTSNS GGGQASLSVS TYTGLIRLLS TCASGSPLGF
460 470 480 490 500
RTLLLLGISS ILKDILLGSG VSANASVSPA LSRPADQIYE IVNLANELLP
510 520 530 540 550
PLPEGVISLP TSTNALVKGS CQKKSSPSTS GKQEDILKIS PREKLLGDQP
560 570 580 590 600
ELLQQFGLDL LPVLVQIYGS SVNGTIRHKC LSVIGKLMYF SSSEMIQSLI
610 620 630 640 650
GDTNISSFLA GVLAWKDPQV LVPALQVAEI LMEKLPETFS KVFVREGVVH
660 670 680 690 700
AVDQLVLVGK PSHASPTDKD NDCVPGSARS RRYRRRSSNA NSDGNQSEEP
710 720 730 740 750
KNPASLTIGA NHNSLDTPTA SFMLRETVSS CAKAFKDKYF PSDGGDVDVG
760 770 780 790 800
VTDDLLHLKN LCTKLTAGID DHKVKGKGKS KASGPFLGDF SASKEEYLIG
810 820 830 840 850
VISEILGEIS KGDGVSTFEF IGSGVVAALL NYFSCGYFSK EKISELNLPK
860 870 880 890 900
LRQEGLRRFK AFLEVALPFD GNEGKVPPMT VLIQKLQNAL SSLERFPVVL
910 920 930 940 950
SHPSRSLSGS ARLSSGLSAL AHPLKLRLCR ASGEKTLRDY SSNIVLIDPL
960 970 980 990 1000
ASLAAVEEFL WPRVQRSESA LKPAAPIGNT EPGTLPSGAG VSSPSSSTPA
1010 1020 1030 1040 1050
STTRRHSSRS RSAINIGDTS KKDPVHEKGT SSSKGKGKGV MKPAQADKGP
1060 1070 1080 1090 1100
QTRSNAQKRA VLDKDTQMKP ASGDSSSEDE ELEISPVDID DALVIEEDDI
1110 1120 1130 1140 1150
SDDEDDDNED VLDDSLPMCT PDKVHDVKLA DSVDDDGLAT SGRQMNPASG
1160 1170 1180 1190 1200
GTSGAAAARA SDSIDTGIGN SYGSRGALSF AAAAMAGLGA ASGRGIRGSR
1210 1220 1230 1240 1250
DLHGRTLNRS SDEPSKLIFT AAGKQLSRHL TIYQAVQRQL MLDEDDDDRF
1260 1270 1280 1290 1300
GGSDLVSSDG SRFNDIYTIM YQRPDSQVNR LSVGGASSTT PSKSTKSATT
1310 1320 1330 1340 1350
NSSVESQSHR ASLLDSILQG ELPCDLEKSN STYNVLALLR VLEGLNQLCP
1360 1370 1380 1390 1400
RLRAQTLSDR FAEGKITSLD DLSTTAAKVP LDEFVNSKLT PKLARQIQDA
1410 1420 1430 1440 1450
LALCSGSLPS WCYQLTRACP FLFPFQTRRQ YFYSTAFGLS RALNRLQQQQ
1460 1470 1480 1490 1500
GADGSGSTNE REMRIGRLQR QKVRVSRNRI LDSAAKVMEM YSSQKAVLEV
1510 1520 1530 1540 1550
EYFGEVGTGL GPTLEFYTLL SHDLQKASLG MWRSSSGDKV SMQIGRDEIE
1560 1570 1580 1590 1600
DGKPSAANRD IVLAPLGLFP RPWPSTADIS EGGQFHKVIE YFRLLGRVMA
1610 1620 1630 1640 1650
KALQDGRLLD VPLSTAFYKL ILGQELDLHD IVLFDAELGK TLQELRVVVA
1660 1670 1680 1690 1700
RKHYLEGVGG DNSSTISDLC LRGCRIEDLS LEFTLPGYPE YILRSGDEIV
1710 1720 1730 1740 1750
DITNLEEYIS LVVDATVKRG VTRQIEAFRS GFNQVFDITS LQIFTPSELD
1760 1770 1780 1790 1800
YLLCGRRELW EVETLAEHIK FDHGYNAKSP AIINLLEIMG ELTADQQRAF
1810 1820 1830 1840 1850
CQFVTGAPRL PPGGLAVLNP KLTIVRKHSS TSSAAANGAG ASETADDDLP
1860 1870 1880
SVMTCANYLK LPPYSTKEIM YKKLLYAINE GQGSFDLS
Length:1,888
Mass (Da):202,928
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFB582F4E2510441
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
B3H700B3H700_ARATH
HECT ubiquitin protein ligase famil...
KAK KAKTUS, UBIQUITIN-PROTEIN LIGASE 3, UBIQUITIN_PROTEIN LIGASE, UPL3, At4g38600
1,794Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAB37516 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g38600 and At4g38610.Curated
The sequence CAB37517 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g38600 and At4g38610.Curated
The sequence CAB80524 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g38600 and At4g38610.Curated
The sequence CAB80525 differs from that shown. Reason: Erroneous gene model prediction. Was originally thought to correspond to two different genes At4g38600 and At4g38610.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY265959 mRNA Translation: AAP91821.1
AL035540 Genomic DNA Translation: CAB37516.1 Sequence problems.
AL035540 Genomic DNA Translation: CAB37517.1 Sequence problems.
AL161593 Genomic DNA Translation: CAB80524.1 Sequence problems.
AL161593 Genomic DNA Translation: CAB80525.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86954.1
CP002687 Genomic DNA Translation: ANM67531.1
AK229635 mRNA Translation: BAF01480.1
BN000268 mRNA Translation: CAE30362.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T05688
T05689

NCBI Reference Sequences

More...
RefSeqi
NP_001329354.1, NM_001342508.1 [Q6WWW4-1]
NP_849567.2, NM_179236.3 [Q6WWW4-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT4G38600.1; AT4G38600.1; AT4G38600 [Q6WWW4-1]
AT4G38600.3; AT4G38600.3; AT4G38600 [Q6WWW4-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
830017

Gramene; a comparative resource for plants

More...
Gramenei
AT4G38600.1; AT4G38600.1; AT4G38600 [Q6WWW4-1]
AT4G38600.3; AT4G38600.3; AT4G38600 [Q6WWW4-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT4G38600

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY265959 mRNA Translation: AAP91821.1
AL035540 Genomic DNA Translation: CAB37516.1 Sequence problems.
AL035540 Genomic DNA Translation: CAB37517.1 Sequence problems.
AL161593 Genomic DNA Translation: CAB80524.1 Sequence problems.
AL161593 Genomic DNA Translation: CAB80525.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE86954.1
CP002687 Genomic DNA Translation: ANM67531.1
AK229635 mRNA Translation: BAF01480.1
BN000268 mRNA Translation: CAE30362.1
PIRiT05688
T05689
RefSeqiNP_001329354.1, NM_001342508.1 [Q6WWW4-1]
NP_849567.2, NM_179236.3 [Q6WWW4-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi15297, 2 interactors
STRINGi3702.AT4G38600.1

PTM databases

iPTMnetiQ6WWW4

Proteomic databases

PaxDbiQ6WWW4
PRIDEiQ6WWW4

Genome annotation databases

EnsemblPlantsiAT4G38600.1; AT4G38600.1; AT4G38600 [Q6WWW4-1]
AT4G38600.3; AT4G38600.3; AT4G38600 [Q6WWW4-1]
GeneIDi830017
GrameneiAT4G38600.1; AT4G38600.1; AT4G38600 [Q6WWW4-1]
AT4G38600.3; AT4G38600.3; AT4G38600 [Q6WWW4-1]
KEGGiath:AT4G38600

Organism-specific databases

AraportiAT4G38600
TAIRilocus:2121224 AT4G38600

Phylogenomic databases

eggNOGiKOG0168 Eukaryota
KOG0170 Eukaryota
COG5021 LUCA
HOGENOMiHOG000238707
InParanoidiQ6WWW4
KOiK10590
OMAiHQESQAI
OrthoDBi34110at2759
PhylomeDBiQ6WWW4

Enzyme and pathway databases

UniPathwayiUPA00143

Miscellaneous databases

Protein Ontology

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PROi
PR:Q6WWW4

Gene expression databases

ExpressionAtlasiQ6WWW4 baseline and differential
GenevisibleiQ6WWW4 AT

Family and domain databases

CDDicd00078 HECTc, 1 hit
Gene3Di1.25.10.10, 1 hit
InterProiView protein in InterPro
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR000569 HECT_dom
IPR035983 Hect_E3_ubiquitin_ligase
PfamiView protein in Pfam
PF00632 HECT, 1 hit
SMARTiView protein in SMART
SM00185 ARM, 3 hits
SM00119 HECTc, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
SSF56204 SSF56204, 1 hit
PROSITEiView protein in PROSITE
PS50237 HECT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiUPL3_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6WWW4
Secondary accession number(s): Q0WN20, Q9SZN9, Q9SZP0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: July 5, 2004
Last modified: October 16, 2019
This is version 134 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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