UniProtKB - Q6WDN9 (Q6WDN9_CAVPO)
Protein
Submitted name:
Preproalbumin
Gene
Alb
Organism
Cavia porcellus (Guinea pig)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 223 | Aspirin-acetylated lysineUniRule annotation | 1 | |
Binding sitei | 264 | BilirubinUniRule annotation | 1 | |
Metal bindingi | 271 | ZincUniRule annotation | 1 | |
Metal bindingi | 273 | ZincUniRule annotation | 1 |
GO - Molecular functioni
- chaperone binding Source: Ensembl
- DNA binding Source: Ensembl
- enterobactin binding Source: Ensembl
- exogenous protein binding Source: Ensembl
- fatty acid binding Source: Ensembl
- identical protein binding Source: Ensembl
- metal ion binding Source: UniProtKB-KW
- oxygen binding Source: Ensembl
- pyridoxal phosphate binding Source: Ensembl
- toxic substance binding Source: Ensembl
GO - Biological processi
- cellular response to starvation Source: Ensembl
- maintenance of mitochondrion location Source: Ensembl
- negative regulation of apoptotic process Source: Ensembl
Keywordsi
Ligand | Metal-bindingUniRule annotation, ZincUniRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: PreproalbuminImported |
Gene namesi | Name:AlbImported |
Organismi | Cavia porcellus (Guinea pig)Imported |
Taxonomic identifieri | 10141 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Hystricomorpha › Caviidae › Cavia |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- Secreted ARBA annotation
Endoplasmic reticulum
- endoplasmic reticulum Source: Ensembl
Extracellular region or secreted
- extracellular exosome Source: Ensembl
Golgi apparatus
- Golgi apparatus Source: Ensembl
Other locations
- protein-containing complex Source: Ensembl
Keywords - Cellular componenti
SecretedARBA annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 18 | Sequence analysisAdd BLAST | 18 | |
ChainiPRO_5015098578 | 19 – 608 | Sequence analysisAdd BLAST | 590 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 77 ↔ 86 | UniRule annotation | ||
Disulfide bondi | 99 ↔ 115 | UniRule annotation | ||
Disulfide bondi | 114 ↔ 125 | UniRule annotation | ||
Disulfide bondi | 148 ↔ 193 | UniRule annotation | ||
Disulfide bondi | 192 ↔ 201 | UniRule annotation | ||
Disulfide bondi | 224 ↔ 270 | UniRule annotation | ||
Disulfide bondi | 269 ↔ 277 | UniRule annotation | ||
Disulfide bondi | 289 ↔ 303 | UniRule annotation | ||
Disulfide bondi | 302 ↔ 313 | UniRule annotation | ||
Disulfide bondi | 340 ↔ 385 | UniRule annotation | ||
Disulfide bondi | 384 ↔ 393 | UniRule annotation | ||
Disulfide bondi | 416 ↔ 462 | UniRule annotation | ||
Disulfide bondi | 461 ↔ 472 | UniRule annotation | ||
Disulfide bondi | 485 ↔ 501 | UniRule annotation | ||
Disulfide bondi | 500 ↔ 511 | UniRule annotation | ||
Disulfide bondi | 538 ↔ 583 | UniRule annotation | ||
Disulfide bondi | 582 ↔ 591 | UniRule annotation |
Keywords - PTMi
Disulfide bondUniRule annotationARBA annotationExpressioni
Gene expression databases
Bgeei | ENSCPOG00000003072, Expressed in liver and 3 other tissues |
Interactioni
GO - Molecular functioni
- chaperone binding Source: Ensembl
- identical protein binding Source: Ensembl
Protein-protein interaction databases
STRINGi | 10141.ENSCPOP00000002781 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 19 – 211 | AlbuminInterPro annotationAdd BLAST | 193 | |
Domaini | 212 – 403 | AlbuminInterPro annotationAdd BLAST | 192 | |
Domaini | 404 – 601 | AlbuminInterPro annotationAdd BLAST | 198 |
Keywords - Domaini
RepeatARBA annotation, SignalSequence analysisARBA annotationPhylogenomic databases
eggNOGi | ENOG502R7EA, Eukaryota |
GeneTreei | ENSGT00390000000113 |
HOGENOMi | CLU_030161_0_0_1 |
OrthoDBi | 906547at2759 |
Family and domain databases
CDDi | cd00015, ALBUMIN, 3 hits |
InterProi | View protein in InterPro IPR000264, ALB/AFP/VDB IPR020858, Serum_albumin-like IPR021177, Serum_albumin/AFP/Afamin IPR020857, Serum_albumin_CS IPR014760, Serum_albumin_N |
PANTHERi | PTHR11385, PTHR11385, 1 hit |
Pfami | View protein in Pfam PF00273, Serum_albumin, 3 hits |
PIRSFi | PIRSF002520, Serum_albumin_subgroup, 1 hit |
PRINTSi | PR00802, SERUMALBUMIN |
SMARTi | View protein in SMART SM00103, ALBUMIN, 3 hits |
SUPFAMi | SSF48552, SSF48552, 3 hits |
PROSITEi | View protein in PROSITE PS00212, ALBUMIN_1, 2 hits PS51438, ALBUMIN_2, 3 hits |
i Sequence
Sequence statusi: Complete.
Q6WDN9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKWVTFISLL FLFSSVYSRG VFRREAHKSE IAHRFNDLGE GHFKGLVLIT
60 70 80 90 100
LSQHLQKSPF EEHVKLVNEV TDFAKACVAD ESAQNCGKAI ATLFGDKVCA
110 120 130 140 150
IPSLRETYGE LADCCAKEDP DRVECFLQHK DDNPNLPPFE RPEPEALCTA
160 170 180 190 200
FKENNDRFIG HYLYEVSRRH PYFYAPELLY YAEKYKNALT ECCEAADKAA
210 220 230 240 250
CLTPKLDAIK EKALVSSAQQ RLKCASLQKF GERAFKAWSV ARLSQKFPKA
260 270 280 290 300
EFAEISTIVT SLTKVTKECC HGDLLECADD RQELAKYMCE HQDSISSKLK
310 320 330 340 350
ECCVKPTLQK AHCILEIQRD ELPTELPDLA VDFVEDKEVC KNFAEAKDVF
360 370 380 390 400
LGTFLYEYSR RHPEYSIGML LRIAKGYEAK LEKCCAEADP HACYAKVFDE
410 420 430 440 450
LQPLIDEPKK LVQQNCELFD KLGEYGFQNA LAVRYTQKAP QVSTPTLVEY
460 470 480 490 500
ARKLGSVGTK CCSLPETERL SCTENYLALI LNRLCILHEK TPVSERVTKC
510 520 530 540 550
CTESLVNRRP CFSALHVDET YVPKPFHADS FTFHADICTL PEKEKQVKKQ
560 570 580 590 600
MALVELVKHK PKASEEQMKT VMGDFAAFLK KCCDADNKEA CFTEDGPKLV
AKCQATLA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAKN02040158 Genomic DNA No translation available. AAKN02040159 Genomic DNA No translation available. AY294645 mRNA Translation: AAQ20088.1 |
RefSeqi | NP_001166576.1, NM_001173105.1 XP_005002728.1, XM_005002671.2 |
Genome annotation databases
Ensembli | ENSCPOT00000003114; ENSCPOP00000002782; ENSCPOG00000003072 |
GeneIDi | 100379232 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAKN02040158 Genomic DNA No translation available. AAKN02040159 Genomic DNA No translation available. AY294645 mRNA Translation: AAQ20088.1 |
RefSeqi | NP_001166576.1, NM_001173105.1 XP_005002728.1, XM_005002671.2 |
3D structure databases
SMRi | Q6WDN9 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10141.ENSCPOP00000002781 |
Protein family/group databases
Allergomei | 10416, Cav p 4.0101 762, Cav p 4 |
Genome annotation databases
Ensembli | ENSCPOT00000003114; ENSCPOP00000002782; ENSCPOG00000003072 |
GeneIDi | 100379232 |
Organism-specific databases
CTDi | 213 |
Phylogenomic databases
eggNOGi | ENOG502R7EA, Eukaryota |
GeneTreei | ENSGT00390000000113 |
HOGENOMi | CLU_030161_0_0_1 |
OrthoDBi | 906547at2759 |
Gene expression databases
Bgeei | ENSCPOG00000003072, Expressed in liver and 3 other tissues |
Family and domain databases
CDDi | cd00015, ALBUMIN, 3 hits |
InterProi | View protein in InterPro IPR000264, ALB/AFP/VDB IPR020858, Serum_albumin-like IPR021177, Serum_albumin/AFP/Afamin IPR020857, Serum_albumin_CS IPR014760, Serum_albumin_N |
PANTHERi | PTHR11385, PTHR11385, 1 hit |
Pfami | View protein in Pfam PF00273, Serum_albumin, 3 hits |
PIRSFi | PIRSF002520, Serum_albumin_subgroup, 1 hit |
PRINTSi | PR00802, SERUMALBUMIN |
SMARTi | View protein in SMART SM00103, ALBUMIN, 3 hits |
SUPFAMi | SSF48552, SSF48552, 3 hits |
PROSITEi | View protein in PROSITE PS00212, ALBUMIN_1, 2 hits PS51438, ALBUMIN_2, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6WDN9_CAVPO | |
Accessioni | Q6WDN9Primary (citable) accession number: Q6WDN9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | December 2, 2020 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |