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UniProtKB - Q6W4T8 (Q6W4T8_DANRE)
Protein
Submitted name:
Hairy-related 11
Gene
her11
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein heterodimerization activity Source: ZFIN
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- anterior/posterior pattern specification Source: GO_Central
- midbrain-hindbrain boundary development Source: ZFIN
- negative regulation of neurogenesis Source: ZFIN
- negative regulation of transcription by RNA polymerase II Source: InterPro
- Notch signaling pathway Source: InterPro
- regulation of neurogenesis Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Hairy-related 11ImportedSubmitted name: Her11Imported |
Gene namesi | Name:her11Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-040824-4, her11 |
Expressioni
Gene expression databases
Bgeei | ENSDARG00000002707, Expressed in gastrula and 16 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 15 – 72 | BHLHInterPro annotationAdd BLAST | 58 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 178 – 202 | DisorderedSequence analysisAdd BLAST | 25 |
Phylogenomic databases
eggNOGi | ENOG502SZH4, Eukaryota |
GeneTreei | ENSGT00730000111282 |
OrthoDBi | 1172143at2759 |
TreeFami | TF323617 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR032644, HES-7 IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR10985:SF84, PTHR10985:SF84, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6W4T8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKSTPTFNMT KTEGIKRRLK PVIEKKRRDR INHNLDALRD LLFKNTADTR
60 70 80 90 100
LQNPKLEKAE ILDLAVQYIK KTIRKTETAR NSNQMDCKST QNQFVISPAG
110 120 130 140 150
PLYTSDYCRR FKTSEQNEVL LNLGVSQNLS GSSKTGNKLV SQKGFLLSPP
160 170 180 190 200
GQNYHQELLL HPESSLYGSS LLRQSTSPSI SSSSQYSSPP SSPTFTSTSC
210 220 230 240 250
SPSSSPPCPS TSCAAFPDQL SPLITPLSLQ RPVFVPQAIL PHMTRDLTPP
260 270
HSPVLALRQD PFPLPNQHAW RPWS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FP015860 Genomic DNA No translation available. BC162348 mRNA Translation: AAI62348.1 BC162354 mRNA Translation: AAI62354.1 AY312568 mRNA Translation: AAQ82052.1 |
RefSeqi | NP_001003886.1, NM_001003886.1 |
Genome annotation databases
Ensembli | ENSDART00000026907.6; ENSDARP00000017640.3; ENSDARG00000002707.10 |
GeneIDi | 445409 |
KEGGi | dre:445409 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FP015860 Genomic DNA No translation available. BC162348 mRNA Translation: AAI62348.1 BC162354 mRNA Translation: AAI62354.1 AY312568 mRNA Translation: AAQ82052.1 |
RefSeqi | NP_001003886.1, NM_001003886.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000026907.6; ENSDARP00000017640.3; ENSDARG00000002707.10 |
GeneIDi | 445409 |
KEGGi | dre:445409 |
Organism-specific databases
CTDi | 445409 |
ZFINi | ZDB-GENE-040824-4, her11 |
Phylogenomic databases
eggNOGi | ENOG502SZH4, Eukaryota |
GeneTreei | ENSGT00730000111282 |
OrthoDBi | 1172143at2759 |
TreeFami | TF323617 |
Gene expression databases
Bgeei | ENSDARG00000002707, Expressed in gastrula and 16 other tissues |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR032644, HES-7 IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR10985:SF84, PTHR10985:SF84, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q6W4T8_DANRE | |
Accessioni | Q6W4T8Primary (citable) accession number: Q6W4T8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | May 25, 2022 | |
This is version 120 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |