Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 105 (08 May 2019)
Sequence version 1 (05 Jul 2004)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Glycerophosphodiester phosphodiesterase domain-containing protein 4

Gene

GDPD4

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi230Divalent metal cationSequence analysis1
Metal bindingi232Divalent metal cationSequence analysis1
Metal bindingi245Divalent metal cationSequence analysis1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
LigandMetal-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Glycerophosphodiester phosphodiesterase domain-containing protein 4 (EC:3.1.-.-)
Alternative name(s):
Glycerophosphodiester phosphodiesterase 6
UgpQ
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GDPD4
Synonyms:GDE6, UGPQ
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 11

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24849 GDPD4

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6W3E5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 17CytoplasmicSequence analysisAdd BLAST17
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Topological domaini39ExtracellularSequence analysis1
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Topological domaini61 – 69CytoplasmicSequence analysis9
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Topological domaini91 – 109ExtracellularSequence analysisAdd BLAST19
Transmembranei110 – 130HelicalSequence analysisAdd BLAST21
Topological domaini131 – 162CytoplasmicSequence analysisAdd BLAST32
Transmembranei163 – 183HelicalSequence analysisAdd BLAST21
Topological domaini184 – 468ExtracellularSequence analysisAdd BLAST285
Transmembranei469 – 489HelicalSequence analysisAdd BLAST21
Topological domaini490 – 623CytoplasmicSequence analysisAdd BLAST134

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000178795

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142671742

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
GDPD4

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74710342

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002519381 – 623Glycerophosphodiester phosphodiesterase domain-containing protein 4Add BLAST623

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi308N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi397N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6W3E5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6W3E5

PeptideAtlas

More...
PeptideAtlasi
Q6W3E5

PRoteomics IDEntifications database

More...
PRIDEi
Q6W3E5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
67742
67743 [Q6W3E5-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6W3E5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6W3E5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000178795 Expressed in 67 organ(s), highest expression level in right testis

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q6W3E5, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000320815

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini198 – 457GP-PDEAdd BLAST260

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2258 Eukaryota
COG0584 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156251

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000232101

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6W3E5

Identification of Orthologs from Complete Genome Data

More...
OMAi
RAQPGEC

Database of Orthologous Groups

More...
OrthoDBi
404866at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6W3E5

TreeFam database of animal gene trees

More...
TreeFami
TF313692

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.20.20.190, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030395 GP_PDE_dom
IPR017946 PLC-like_Pdiesterase_TIM-brl

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03009 GDPD, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51695 SSF51695, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51704 GP_PDE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6W3E5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLFLWIETS SEYFNFDWVT FLGTGYWFFW SIFILSLARI LTAYSSLLLL
60 70 80 90 100
LGFLLLWERI ELYLHLCHKI LILLVILLCV ILMFIICKFW KERWLVAGLS
110 120 130 140 150
MQIFAPYVHL VSITVMVILF WPVAFYVACL EREVRMRRYR MTHSEKKRLK
160 170 180 190 200
QCNVITRLRG LQVPVGLPFL LILLGLYLMP LGIYSPCIQE KENLGPKPTI
210 220 230 240 250
FGHRGAPMLG PENTMMSFEK AVEHGAHGLE TDIHLSYDHV PFLMHDFDLK
260 270 280 290 300
RTTNIGEVQP ESACENPAFF NWDFLSTLNA GKWFVKPELR PFYNMKPLSE
310 320 330 340 350
ADKERARNQS IPTLADLLTL AEKERKFVIF DLHRPPPKHP LRHTFVRQVV
360 370 380 390 400
SVILASKIEQ HLIFWLPAHD RQYVRSVAPG FQHVGRLVSI ETLAKNNISI
410 420 430 440 450
INVDYKKLFP NGLRDYKAAN IHINVYTVNE PWLFSLAWCS RINSVTTDNI
460 470 480 490 500
GLLSQLDHPH FFMTPKFYVF MWLLADIISV LFIVAIFCFH WRRETEKEKL
510 520 530 540 550
FETSSTRTDT QSGNLHIAMK PPVRVVEGPW TLAALYPALP KSGKEHQGHF
560 570 580 590 600
NFAAPSKKLL PIKNAVTPLK PGKHEIQPPM PTVVFELTQA PTRQATSEAT
610 620
FQTTLPTLKV DKPTMPSIEV PYP
Length:623
Mass (Da):71,996
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C8C81D1B735A365
GO
Isoform 2 (identifier: Q6W3E5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     514-520: NLHIAMK → SKNEEDR
     521-623: Missing.

Show »
Length:520
Mass (Da):60,820
Checksum:iC5B585895177409A
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_055872220K → R. Corresponds to variant dbSNP:rs2729772Ensembl.1
Natural variantiVAR_055873383H → Y. Corresponds to variant dbSNP:rs11237146Ensembl.1
Natural variantiVAR_055874390I → V. Corresponds to variant dbSNP:rs11237145Ensembl.1
Natural variantiVAR_064764396N → K1 Publication1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_020811514 – 520NLHIAMK → SKNEEDR in isoform 2. 1 Publication7
Alternative sequenceiVSP_020812521 – 623Missing in isoform 2. 1 PublicationAdd BLAST103

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY313782 mRNA Translation: AAQ72549.1
AY326450 mRNA Translation: AAP92403.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS8249.1 [Q6W3E5-2]

NCBI Reference Sequences

More...
RefSeqi
NP_878253.1, NM_182833.1 [Q6W3E5-2]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000315938; ENSP00000320815; ENSG00000178795 [Q6W3E5-2]
ENST00000376217; ENSP00000365390; ENSG00000178795 [Q6W3E5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
220032

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:220032

UCSC genome browser

More...
UCSCi
uc001oyf.3 human [Q6W3E5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY313782 mRNA Translation: AAQ72549.1
AY326450 mRNA Translation: AAP92403.1
CCDSiCCDS8249.1 [Q6W3E5-2]
RefSeqiNP_878253.1, NM_182833.1 [Q6W3E5-2]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiQ6W3E5, 1 interactor
STRINGi9606.ENSP00000320815

PTM databases

iPTMnetiQ6W3E5
PhosphoSitePlusiQ6W3E5

Polymorphism and mutation databases

BioMutaiGDPD4
DMDMi74710342

Proteomic databases

jPOSTiQ6W3E5
PaxDbiQ6W3E5
PeptideAtlasiQ6W3E5
PRIDEiQ6W3E5
ProteomicsDBi67742
67743 [Q6W3E5-2]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
220032
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000315938; ENSP00000320815; ENSG00000178795 [Q6W3E5-2]
ENST00000376217; ENSP00000365390; ENSG00000178795 [Q6W3E5-1]
GeneIDi220032
KEGGihsa:220032
UCSCiuc001oyf.3 human [Q6W3E5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
220032

GeneCards: human genes, protein and diseases

More...
GeneCardsi
GDPD4

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0035940
HGNCiHGNC:24849 GDPD4
neXtProtiNX_Q6W3E5
OpenTargetsiENSG00000178795
PharmGKBiPA142671742

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2258 Eukaryota
COG0584 LUCA
GeneTreeiENSGT00940000156251
HOGENOMiHOG000232101
InParanoidiQ6W3E5
OMAiRAQPGEC
OrthoDBi404866at2759
PhylomeDBiQ6W3E5
TreeFamiTF313692

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
220032

Protein Ontology

More...
PROi
PR:Q6W3E5

Gene expression databases

BgeeiENSG00000178795 Expressed in 67 organ(s), highest expression level in right testis

Family and domain databases

Gene3Di3.20.20.190, 1 hit
InterProiView protein in InterPro
IPR030395 GP_PDE_dom
IPR017946 PLC-like_Pdiesterase_TIM-brl
PfamiView protein in Pfam
PF03009 GDPD, 1 hit
SUPFAMiSSF51695 SSF51695, 1 hit
PROSITEiView protein in PROSITE
PS51704 GP_PDE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGDPD4_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6W3E5
Secondary accession number(s): Q7Z5B0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: July 5, 2004
Last modified: May 8, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again