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Entry version 121 (11 Dec 2019)
Sequence version 1 (05 Jul 2004)
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Protein

Inter-alpha-trypsin inhibitor heavy chain H6

Gene

ITIH6

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inter-alpha-trypsin inhibitor heavy chain H6
Alternative name(s):
Inter-alpha-trypsin inhibitor heavy chain H5-like protein
Short name:
Inter-alpha inhibitor H5-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ITIH6
Synonyms:ITIH5L
ORF Names:UNQ6369/PRO21074
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000102313.8

Human Gene Nomenclature Database

More...
HGNCi
HGNC:28907 ITIH6

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6UXX5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
347365

Open Targets

More...
OpenTargetsi
ENSG00000102313

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134930661

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6UXX5 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
ITIH6

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74762375

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000028568024 – 1313Inter-alpha-trypsin inhibitor heavy chain H6Add BLAST1290

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi83N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi374N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi540N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi594N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi971N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1231N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6UXX5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6UXX5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6UXX5

PeptideAtlas

More...
PeptideAtlasi
Q6UXX5

PRoteomics IDEntifications database

More...
PRIDEi
Q6UXX5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
67671

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6UXX5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6UXX5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000102313 Expressed in 9 organ(s), highest expression level in gastrocnemius

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6UXX5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA000506

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
131428, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q6UXX5, 10 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000218436

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6UXX5 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6UXX5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini24 – 150VITPROSITE-ProRule annotationAdd BLAST127
Domaini283 – 469VWFAPROSITE-ProRule annotationAdd BLAST187

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi636 – 639Poly-Ser4
Compositional biasi738 – 994Pro-richAdd BLAST257
Compositional biasi917 – 920Poly-Thr4
Compositional biasi999 – 1002Poly-Leu4
Compositional biasi1192 – 1195Poly-Ala4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ITIH family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IEJB Eukaryota
COG2304 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162980

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113117

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6UXX5

Identification of Orthologs from Complete Genome Data

More...
OMAi
GQFQHAD

Database of Orthologous Groups

More...
OrthoDBi
955432at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6UXX5

TreeFam database of animal gene trees

More...
TreeFami
TF328982

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010600 ITI_HC_C
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06668 ITI_HC_C, 1 hit
PF08487 VIT, 1 hit
PF00092 VWA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00609 VIT, 1 hit
SM00327 VWA, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300 SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51468 VIT, 1 hit
PS50234 VWFA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6UXX5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGWRYLICV SFLLTILLEL TYQGPPVPAS SSTKLLMTSY SMRSTVVSRY
60 70 80 90 100
AHTLVTSVLF NPHAEAHEAI FDLDLPHLAF ISNFTMTINN KVYIAEVKEK
110 120 130 140 150
HQAKKIYEEA HQQGKTAAHV GIRDRESEKF RISTSLAAGT EVTFSLAYEE
160 170 180 190 200
LLQRHQGQYQ LVVSLRPGQL VKRLSIEVTV SERTGISYVH IPPLRTGRLR
210 220 230 240 250
TNAHASEVDS PPSTRIERGE TCVRITYCPT LQDQSSISGS GIMADFLVQY
260 270 280 290 300
DVVMEDIIGD VQIYDDYFIH YFAPRGLPPM EKNVVFVIDV SSSMFGTKME
310 320 330 340 350
QTKTAMNVIL SDLQANDYFN IISFSDTVNV WKAGGSIQAT IQNVHSAKDY
360 370 380 390 400
LHCMEADGWT DVNSALLAAA SVLNHSNQEP GRGPSVGRIP LIIFLTDGEP
410 420 430 440 450
TAGVTTPSVI LSNVRQALGH RVSLFSLAFG DDADFTLLRR LSLENRGIAR
460 470 480 490 500
RIYEDTDAAL QLKGLYEEIS MPLLADVRLN YLGGLVGASP WAVFPNYFGG
510 520 530 540 550
SELVVAGQVQ PGKQELGIHL AARGPKDQLL VAHHSEGATN NSQKAFGCPG
560 570 580 590 600
EPAPNVAHFI RRLWAYVTIG ELLDAHFQAR DTTTRHLLAA KVLNLSLEYN
610 620 630 640 650
FVTPLTSLVM VQPKQASEET RRQTSTSAGP DTIMPSSSSR HGLGVSTAQP
660 670 680 690 700
ALVPKVISPK SRPVKPKFYL SSTTTASTKK MLSSKELEPL GESPHTLSMP
710 720 730 740 750
TYPKAKIPAQ QDSGTLAQPT LRTKPTILVP SNSGTLLPLK PGSLSHQNPD
760 770 780 790 800
ILPTNSRTQV PPVKPGIPAS PKADTVKCVT PLHSKPGAPS HPQLGALTSQ
810 820 830 840 850
APKGLPQSRP GVSTLQVPKY PLHTRPRVPA PKTRNNMPHL GPGILLSKTP
860 870 880 890 900
KILLSLKPSA PPHQISTSIS LSKPETPNPH MPQTPLPPRP DRPRPPLPES
910 920 930 940 950
LSTFPNTISS STGPSSTTTT SVLGEPLPMP FTPTLPPGRF WHQYDLLPGP
960 970 980 990 1000
QRTRQVLGPS RPGVPTMSLL NSSRPTPEGS PPNLPILLPS SILPEAISLL
1010 1020 1030 1040 1050
LLPEELELLS ESMVESKFVE SLNPPAFYTF LTPDEDGSPN WDGNSEEILG
1060 1070 1080 1090 1100
GAGGSMESQG SSVGLAKGTL PSIFTFSSSV DGDPHFVIQI PHSEEKICFT
1110 1120 1130 1140 1150
LNGHPGDLLQ LIEDPKAGLH VSGKLLGAPP RPGHKDQTRT YFQIITVTTD
1160 1170 1180 1190 1200
KPRAYTITIS RSSISLRGEG TLRLSWDQPA LLKRPQLELY VAAAARLTLR
1210 1220 1230 1240 1250
LGPYLEFLVL RHRYRHPSTL QLPHLGFYVA NGSGLSPSAR GLIGQFQHAD
1260 1270 1280 1290 1300
IRLVTGPMGP CLRRHHGPDV PVILGKRLLK DSPRLLPRWA SCWLVKRSHV
1310
ELLLGHPYLS YVL
Length:1,313
Mass (Da):143,187
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4C63CF26AF187734
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_032042387G → R. Corresponds to variant dbSNP:rs34188213Ensembl.1
Natural variantiVAR_032043561R → C. Corresponds to variant dbSNP:rs34004499Ensembl.1
Natural variantiVAR_0320441041W → S. Corresponds to variant dbSNP:rs17316491Ensembl.1
Natural variantiVAR_0320451170G → A. Corresponds to variant dbSNP:rs35355718Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358170 mRNA Translation: AAQ88537.1
Z98046 Genomic DNA No translation available.
AL022575 Genomic DNA No translation available.
CH471154 Genomic DNA Translation: EAW93186.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS14361.1

NCBI Reference Sequences

More...
RefSeqi
NP_940912.1, NM_198510.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000218436; ENSP00000218436; ENSG00000102313

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
347365

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:347365

UCSC genome browser

More...
UCSCi
uc004dtj.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358170 mRNA Translation: AAQ88537.1
Z98046 Genomic DNA No translation available.
AL022575 Genomic DNA No translation available.
CH471154 Genomic DNA Translation: EAW93186.1
CCDSiCCDS14361.1
RefSeqiNP_940912.1, NM_198510.2

3D structure databases

SMRiQ6UXX5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi131428, 1 interactor
IntActiQ6UXX5, 10 interactors
STRINGi9606.ENSP00000218436

PTM databases

iPTMnetiQ6UXX5
PhosphoSitePlusiQ6UXX5

Polymorphism and mutation databases

BioMutaiITIH6
DMDMi74762375

Proteomic databases

EPDiQ6UXX5
MassIVEiQ6UXX5
PaxDbiQ6UXX5
PeptideAtlasiQ6UXX5
PRIDEiQ6UXX5
ProteomicsDBi67671

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
347365

Genome annotation databases

EnsembliENST00000218436; ENSP00000218436; ENSG00000102313
GeneIDi347365
KEGGihsa:347365
UCSCiuc004dtj.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
347365
DisGeNETi347365
EuPathDBiHostDB:ENSG00000102313.8

GeneCards: human genes, protein and diseases

More...
GeneCardsi
ITIH6
HGNCiHGNC:28907 ITIH6
HPAiHPA000506
neXtProtiNX_Q6UXX5
OpenTargetsiENSG00000102313
PharmGKBiPA134930661

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IEJB Eukaryota
COG2304 LUCA
GeneTreeiENSGT00940000162980
HOGENOMiHOG000113117
InParanoidiQ6UXX5
OMAiGQFQHAD
OrthoDBi955432at2759
PhylomeDBiQ6UXX5
TreeFamiTF328982

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
347365
PharosiQ6UXX5 Tdark

Protein Ontology

More...
PROi
PR:Q6UXX5
RNActiQ6UXX5 protein

Gene expression databases

BgeeiENSG00000102313 Expressed in 9 organ(s), highest expression level in gastrocnemius
GenevisibleiQ6UXX5 HS

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR010600 ITI_HC_C
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF06668 ITI_HC_C, 1 hit
PF08487 VIT, 1 hit
PF00092 VWA, 1 hit
SMARTiView protein in SMART
SM00609 VIT, 1 hit
SM00327 VWA, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS51468 VIT, 1 hit
PS50234 VWFA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiITIH6_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6UXX5
Secondary accession number(s): A6NN03
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: July 5, 2004
Last modified: December 11, 2019
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
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