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Protein

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9

Gene

B3GNT9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Enzyme and pathway databases

ReactomeiR-HSA-913709 O-linked glycosylation of mucins

Protein family/group databases

CAZyiGT31 Glycosyltransferase Family 31

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9Imported (EC:2.4.1.-)
Short name:
BGnT-9Imported
Short name:
Beta-1,3-Gn-T9
Short name:
Beta-1,3-N-acetylglucosaminyltransferase 9
Short name:
Beta3Gn-T9Imported
Gene namesi
Name:B3GNT9Imported
ORF Names:UNQ1922/PRO4397
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 16

Organism-specific databases

EuPathDBiHostDB:ENSG00000237172.3
HGNCiHGNC:28714 B3GNT9
neXtProtiNX_Q6UX72

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 10CytoplasmicSequence analysis10
Transmembranei11 – 27Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST17
Topological domaini28 – 402LumenalSequence analysisAdd BLAST375

Keywords - Cellular componenti

Golgi apparatus, Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi84752
OpenTargetsiENSG00000237172
PharmGKBiPA164716431

Polymorphism and mutation databases

BioMutaiB3GNT9
DMDMi74738184

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003527621 – 402UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9Add BLAST402

Proteomic databases

PaxDbiQ6UX72
PeptideAtlasiQ6UX72
PRIDEiQ6UX72
ProteomicsDBi67574
TopDownProteomicsiQ6UX72

PTM databases

iPTMnetiQ6UX72
PhosphoSitePlusiQ6UX72

Expressioni

Gene expression databases

BgeeiENSG00000237172
CleanExiHS_B3GNT9
GenevisibleiQ6UX72 HS

Organism-specific databases

HPAiHPA052743
HPA062734

Interactioni

Protein-protein interaction databases

BioGridi124240, 2 interactors
IntActiQ6UX72, 2 interactors
STRINGi9606.ENSP00000400157

Structurei

3D structure databases

ProteinModelPortaliQ6UX72
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 31 family.Sequence analysis

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2287 Eukaryota
ENOG410ZZ1B LUCA
GeneTreeiENSGT00760000118879
HOGENOMiHOG000232195
HOVERGENiHBG050653
InParanoidiQ6UX72
KOiK18705
OMAiFRTFGIP
OrthoDBiEOG091G0AXM
PhylomeDBiQ6UX72
TreeFamiTF318639

Family and domain databases

InterProiView protein in InterPro
IPR002659 Glyco_trans_31
PANTHERiPTHR11214 PTHR11214, 1 hit
PfamiView protein in Pfam
PF01762 Galactosyl_T, 1 hit

Sequencei

Sequence statusi: Complete.

Q6UX72-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRRRLRLRRD ALLTLLLGAS LGLLLYAQRD GAAPTASAPR GRGRAAPRPT
60 70 80 90 100
PGPRAFQLPD AGAAPPAYEG DTPAPPTPTG PFDFARYLRA KDQRRFPLLI
110 120 130 140 150
NQPHKCRGDG APGGRPDLLI AVKSVAEDFE RRQAVRQTWG AEGRVQGALV
160 170 180 190 200
RRVFLLGVPR GAGSGGADEV GEGARTHWRA LLRAESLAYA DILLWAFDDT
210 220 230 240 250
FFNLTLKEIH FLAWASAFCP DVRFVFKGDA DVFVNVGNLL EFLAPRDPAQ
260 270 280 290 300
DLLAGDVIVH ARPIRTRASK YYIPEAVYGL PAYPAYAGGG GFVLSGATLH
310 320 330 340 350
RLAGACAQVE LFPIDDVFLG MCLQRLRLTP EPHPAFRTFG IPQPSAAPHL
360 370 380 390 400
STFDPCFYRE LVVVHGLSAA DIWLMWRLLH GPHGPACAHP QPVAAGPFQW

DS
Length:402
Mass (Da):43,751
Last modified:July 5, 2004 - v1
Checksum:iE4FFEBDFD5F8F2FB
GO

Sequence cautioni

The sequence BC012191 differs from that shown. Reason: Frameshift at position 81.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358485 mRNA Translation: AAQ88849.1
CH471092 Genomic DNA Translation: EAW83079.1
BC012191 mRNA No translation available.
CCDSiCCDS45509.1
RefSeqiNP_171608.2, NM_033309.2
UniGeneiHs.744158

Genome annotation databases

EnsembliENST00000449549; ENSP00000400157; ENSG00000237172
GeneIDi84752
KEGGihsa:84752
UCSCiuc002erf.4 human

Similar proteinsi

Entry informationi

Entry nameiB3GN9_HUMAN
AccessioniPrimary (citable) accession number: Q6UX72
Secondary accession number(s): Q96EK0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2008
Last sequence update: July 5, 2004
Last modified: June 20, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 16
    Human chromosome 16: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

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