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Entry version 119 (02 Dec 2020)
Sequence version 1 (21 Dec 2004)
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Protein

Bombesin receptor-activated protein C6orf89

Gene

C6orf89

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exhibits histone deacetylase (HDAC) enhancer properties (PubMed:23460338). May play a role in cell cycle progression and wound repair of bronchial epithelial cells (PubMed:21857995).2 Publications

Miscellaneous

Named amfion, after 'the 4 Amfion heroes in Greek mythology and their deeds in different locations within the mother land.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q6UWU4

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Bombesin receptor-activated protein C6orf89
Alternative name(s):
Amfion1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:C6orf89
Synonyms:BRAP
ORF Names:UNQ177/PRO203
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...
EuPathDBi
HostDB:ENSG00000198663.16

Human Gene Nomenclature Database

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HGNCi
HGNC:21114, C6orf89

Online Mendelian Inheritance in Man (OMIM)

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MIMi
616642, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6UWU4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 58Cytoplasmic1 PublicationAdd BLAST58
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei59 – 79HelicalSequence analysisAdd BLAST21
Topological domaini80 – 347Extracellular1 PublicationAdd BLAST268

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Membrane, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
221477

Open Targets

More...
OpenTargetsi
ENSG00000198663

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134986915

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q6UWU4, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
C6orf89

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002376211 – 347Bombesin receptor-activated protein C6orf89Add BLAST347

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6UWU4

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
Q6UWU4

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6UWU4

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6UWU4

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6UWU4

PeptideAtlas

More...
PeptideAtlasi
Q6UWU4

PRoteomics IDEntifications database

More...
PRIDEi
Q6UWU4

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
65011
67525 [Q6UWU4-1]
67526 [Q6UWU4-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6UWU4

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6UWU4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000198663, Expressed in amniotic fluid and 220 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6UWU4, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6UWU4, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000198663, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer (PubMed:23460338).

Interacts with BRS3 (PubMed:21857995).

Interacts (via N-terminus) with SIN3B (PubMed:23460338).

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
128732, 6 interactors

Protein interaction database and analysis system

More...
IntActi
Q6UWU4, 3 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000347322

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q6UWU4, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502S363, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014270

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_796829_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6UWU4

Identification of Orthologs from Complete Genome Data

More...
OMAi
TTSEPCI

Database of Orthologous Groups

More...
OrthoDBi
1010604at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6UWU4

TreeFam database of animal gene trees

More...
TreeFami
TF335525

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038757, BRAP

The PANTHER Classification System

More...
PANTHERi
PTHR35259, PTHR35259, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q6UWU4-1) [UniParc]FASTAAdd to basket
Also known as: 42/116mp

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLAANEISI YDKLSETVDL VRQTGHQCGM SEKAIEKFIR QLLEKNEPQR
60 70 80 90 100
PPPQYPLLIV VYKVLATLGL ILLTAYFVIQ PFSPLAPEPV LSGAHTWRSL
110 120 130 140 150
IHHIRLMSLP IAKKYMSENK GVPLHGGDED RPFPDFDPWW TNDCEQNESE
160 170 180 190 200
PIPANCTGCA QKHLKVMLLE DAPRKFERLH PLVIKTGKPL LEEEIQHFLC
210 220 230 240 250
QYPEATEGFS EGFFAKWWRC FPERWFPFPY PWRRPLNRSQ MLRELFPVFT
260 270 280 290 300
HLPFPKDASL NKCSFLHPEP VVGSKMHKMP DLFIIGSGEA MLQLIPPFQC
310 320 330 340
RRHCQSVAMP IEPGDIGYVD TTHWKVYVIA RGVQPLVICD GTAFSEL
Length:347
Mass (Da):39,870
Last modified:December 21, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEFE39F1A9A514595
GO
Isoform 2 (identifier: Q6UWU4-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MDFILEDM

Show »
Length:354
Mass (Da):40,734
Checksum:i737E3B396D0BE209
GO
Isoform 3 (identifier: Q6UWU4-3) [UniParc]FASTAAdd to basket
Also known as: 34/64sp

The sequence of this isoform differs from the canonical sequence as follows:
     1-106: Missing.

Show »
Length:241
Mass (Da):27,857
Checksum:i9B477916B1427416
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH23605 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
The sequence CAD98021 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti5A → V in CAD98021 (PubMed:17974005).Curated1
Sequence conflicti171D → H in CCA30148 (PubMed:23460338).Curated1
Sequence conflicti171D → H in CCA30149 (PubMed:23460338).Curated1
Sequence conflicti189P → A in BAH14355 (PubMed:14702039).Curated1
Sequence conflicti327Y → C in CAD98021 (PubMed:17974005).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0581111 – 106Missing in isoform 3. Add BLAST106
Alternative sequenceiVSP_0185981M → MDFILEDM in isoform 2. 4 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FR832871 mRNA Translation: CCA30148.1
FR832872 mRNA Translation: CCA30149.1
AY358637 mRNA Translation: AAQ89000.1
AK172780 mRNA Translation: BAD18761.1
AK300351 mRNA Translation: BAG62093.1
AK315984 mRNA Translation: BAH14355.1
BX538108 mRNA Translation: CAD98021.1 Different initiation.
AL122034 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03920.1
CH471081 Genomic DNA Translation: EAX03919.1
BC023605 mRNA Translation: AAH23605.2 Different initiation.
BC095423 mRNA Translation: AAH95423.1
BC105947 mRNA Translation: AAI05948.1
BC107489 mRNA Translation: AAI07490.1
BC105946 mRNA Translation: AAI05947.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS4827.1 [Q6UWU4-2]
CCDS69100.1 [Q6UWU4-1]
CCDS75444.1 [Q6UWU4-3]

NCBI Reference Sequences

More...
RefSeqi
NP_001273564.1, NM_001286635.1 [Q6UWU4-1]
NP_001273565.1, NM_001286636.1 [Q6UWU4-3]
NP_001273566.1, NM_001286637.1 [Q6UWU4-3]
NP_689947.2, NM_152734.3 [Q6UWU4-2]
XP_011512679.1, XM_011514377.2 [Q6UWU4-1]
XP_016865921.1, XM_017010432.1 [Q6UWU4-1]
XP_016865922.1, XM_017010433.1 [Q6UWU4-1]
XP_016865923.1, XM_017010434.1 [Q6UWU4-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000355190; ENSP00000347322; ENSG00000198663 [Q6UWU4-2]
ENST00000359359; ENSP00000352316; ENSG00000198663 [Q6UWU4-3]
ENST00000373685; ENSP00000362789; ENSG00000198663 [Q6UWU4-1]
ENST00000480824; ENSP00000475947; ENSG00000198663 [Q6UWU4-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
221477

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:221477

UCSC genome browser

More...
UCSCi
uc003omw.4, human [Q6UWU4-1]
uc063oez.1, human

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR832871 mRNA Translation: CCA30148.1
FR832872 mRNA Translation: CCA30149.1
AY358637 mRNA Translation: AAQ89000.1
AK172780 mRNA Translation: BAD18761.1
AK300351 mRNA Translation: BAG62093.1
AK315984 mRNA Translation: BAH14355.1
BX538108 mRNA Translation: CAD98021.1 Different initiation.
AL122034 Genomic DNA No translation available.
CH471081 Genomic DNA Translation: EAX03920.1
CH471081 Genomic DNA Translation: EAX03919.1
BC023605 mRNA Translation: AAH23605.2 Different initiation.
BC095423 mRNA Translation: AAH95423.1
BC105947 mRNA Translation: AAI05948.1
BC107489 mRNA Translation: AAI07490.1
BC105946 mRNA Translation: AAI05947.1
CCDSiCCDS4827.1 [Q6UWU4-2]
CCDS69100.1 [Q6UWU4-1]
CCDS75444.1 [Q6UWU4-3]
RefSeqiNP_001273564.1, NM_001286635.1 [Q6UWU4-1]
NP_001273565.1, NM_001286636.1 [Q6UWU4-3]
NP_001273566.1, NM_001286637.1 [Q6UWU4-3]
NP_689947.2, NM_152734.3 [Q6UWU4-2]
XP_011512679.1, XM_011514377.2 [Q6UWU4-1]
XP_016865921.1, XM_017010432.1 [Q6UWU4-1]
XP_016865922.1, XM_017010433.1 [Q6UWU4-1]
XP_016865923.1, XM_017010434.1 [Q6UWU4-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi128732, 6 interactors
IntActiQ6UWU4, 3 interactors
STRINGi9606.ENSP00000347322

PTM databases

iPTMnetiQ6UWU4
PhosphoSitePlusiQ6UWU4

Polymorphism and mutation databases

BioMutaiC6orf89

Proteomic databases

EPDiQ6UWU4
jPOSTiQ6UWU4
MassIVEiQ6UWU4
MaxQBiQ6UWU4
PaxDbiQ6UWU4
PeptideAtlasiQ6UWU4
PRIDEiQ6UWU4
ProteomicsDBi65011
67525 [Q6UWU4-1]
67526 [Q6UWU4-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
2729, 32 antibodies

The DNASU plasmid repository

More...
DNASUi
221477

Genome annotation databases

EnsembliENST00000355190; ENSP00000347322; ENSG00000198663 [Q6UWU4-2]
ENST00000359359; ENSP00000352316; ENSG00000198663 [Q6UWU4-3]
ENST00000373685; ENSP00000362789; ENSG00000198663 [Q6UWU4-1]
ENST00000480824; ENSP00000475947; ENSG00000198663 [Q6UWU4-1]
GeneIDi221477
KEGGihsa:221477
UCSCiuc003omw.4, human [Q6UWU4-1]
uc063oez.1, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
221477
DisGeNETi221477
EuPathDBiHostDB:ENSG00000198663.16

GeneCards: human genes, protein and diseases

More...
GeneCardsi
C6orf89
HGNCiHGNC:21114, C6orf89
HPAiENSG00000198663, Low tissue specificity
MIMi616642, gene
neXtProtiNX_Q6UWU4
OpenTargetsiENSG00000198663
PharmGKBiPA134986915

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG502S363, Eukaryota
GeneTreeiENSGT00390000014270
HOGENOMiCLU_796829_0_0_1
InParanoidiQ6UWU4
OMAiTTSEPCI
OrthoDBi1010604at2759
PhylomeDBiQ6UWU4
TreeFamiTF335525

Enzyme and pathway databases

PathwayCommonsiQ6UWU4

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
221477, 41 hits in 843 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
C6orf89, human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
C6orf89

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
221477
PharosiQ6UWU4, Tbio

Protein Ontology

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PROi
PR:Q6UWU4
RNActiQ6UWU4, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000198663, Expressed in amniotic fluid and 220 other tissues
ExpressionAtlasiQ6UWU4, baseline and differential
GenevisibleiQ6UWU4, HS

Family and domain databases

InterProiView protein in InterPro
IPR038757, BRAP
PANTHERiPTHR35259, PTHR35259, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCF089_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6UWU4
Secondary accession number(s): B4DTT1
, B7Z9L9, F4NAR0, F4NAR1, Q5TDC5, Q6ZMG5, Q7Z356, Q8IZ35
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 21, 2004
Last modified: December 2, 2020
This is version 119 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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