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UniProtKB - Q6UW68 (TM205_HUMAN)

Entry version 123 (07 Oct 2020)
Sequence version 1 (05 Jul 2004)
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Protein

Transmembrane protein 205

Gene

TMEM205

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin.1 Publication

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6UW68

Protein family/group databases

Transport Classification Database

More...TCDBi		9.A.55.1.1, the tmem205 (tmem205) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transmembrane protein 205
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMEM205
ORF Names:UNQ501/PRO1018
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000105518.13

Human Gene Nomenclature Database

More...HGNCi		HGNC:29631, TMEM205

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		613771, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6UW68

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Transmembranei53 – 73HelicalSequence analysisAdd BLAST21
Transmembranei81 – 101HelicalSequence analysisAdd BLAST21
Transmembranei166 – 186HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		374882

Open Targets

More...OpenTargetsi		ENSG00000105518

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA162406385

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6UW68, Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TMEM205

Domain mapping of disease mutations (DMDM)

More...DMDMi		74749383

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003175011 – 189Transmembrane protein 205Add BLAST189

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6UW68

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6UW68

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6UW68

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6UW68

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6UW68

PeptideAtlas

More...PeptideAtlasi		Q6UW68

PRoteomics IDEntifications database

More...PRIDEi		Q6UW68

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		67453

Consortium for Top Down Proteomics

More...TopDownProteomicsi		Q6UW68

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6UW68

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6UW68

SwissPalm database of S-palmitoylation events

More...SwissPalmi		Q6UW68

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Widely expressed with highest levels in pancreas, followed by adrenal gland, thyroid, liver, mammary gland, prostate, kidney, and retina; lowest levels in skeletal muscle. Overexpressed in cisplatin-resistant cancer cells (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000105518, Expressed in right lobe of liver and 211 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6UW68, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q6UW68, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000105518, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TMEM205 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2886, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000016298

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6UW68

Identification of Orthologs from Complete Genome Data

More...OMAi		WEASQLC

Database of Orthologous Groups

More...OrthoDBi		1785664at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6UW68

TreeFam database of animal gene trees

More...TreeFami		TF323838

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR025423, DUF4149
IPR042623, TMEM205

The PANTHER Classification System

More...PANTHERi		PTHR46916, PTHR46916, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF13664, DUF4149, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

Q6UW68-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEGGNLGGL IKMVHLLVLS GAWGMQMWVT FVSGFLLFRS LPRHTFGLVQ 
        60         70         80         90        100
SKLFPFYFHI SMGCAFINLC ILASQHAWAQ LTFWEASQLY LLFLSLTLAT 
       110        120        130        140        150
VNARWLEPRT TAAMWALQTV EKERGLGGEV PGSHQGPDPY RQLREKDPKY 
       160        170        180 
SALRQNFFRY HGLSSLCNLG CVLSNGLCLA GLALEIRSL
Length:189
Mass (Da):21,198
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFCC1C48C5B1601B5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7ELQ9K7ELQ9_HUMAN
Transmembrane protein 205
TMEM205
170Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EJQ9K7EJQ9_HUMAN
Transmembrane protein 205
TMEM205
107Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ER05K7ER05_HUMAN
Transmembrane protein 205
TMEM205
88Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EM09K7EM09_HUMAN
Transmembrane protein 205
TMEM205
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPR0K7EPR0_HUMAN
Transmembrane protein 205
TMEM205
128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EMV9K7EMV9_HUMAN
Transmembrane protein 205
TMEM205
123Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY358949 mRNA Translation: AAQ89308.1
AK291979 mRNA Translation: BAF84668.1
CH471106 Genomic DNA Translation: EAW84191.1
BC064948 mRNA Translation: AAH64948.1
BC091472 mRNA Translation: AAH91472.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS32909.1

NCBI Reference Sequences

More...RefSeqi		NP_001138888.1, NM_001145416.1
NP_001308041.1, NM_001321112.1
NP_001308042.1, NM_001321113.1
NP_001308043.1, NM_001321114.1
NP_212133.1, NM_033408.3
NP_940938.1, NM_198536.2
XP_005259956.1, XM_005259899.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000354882; ENSP00000346954; ENSG00000105518
ENST00000447337; ENSP00000398258; ENSG00000105518
ENST00000586590; ENSP00000466986; ENSG00000105518
ENST00000586956; ENSP00000465483; ENSG00000105518
ENST00000587948; ENSP00000465149; ENSG00000105518
ENST00000588560; ENSP00000466495; ENSG00000105518
ENST00000589555; ENSP00000465553; ENSG00000105518
ENST00000593256; ENSP00000468733; ENSG00000105518

Database of genes from NCBI RefSeq genomes

More...GeneIDi		374882

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:374882

UCSC genome browser

More...UCSCi		uc002mqz.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358949 mRNA Translation: AAQ89308.1
AK291979 mRNA Translation: BAF84668.1
CH471106 Genomic DNA Translation: EAW84191.1
BC064948 mRNA Translation: AAH64948.1
BC091472 mRNA Translation: AAH91472.1
CCDSiCCDS32909.1
RefSeqiNP_001138888.1, NM_001145416.1
NP_001308041.1, NM_001321112.1
NP_001308042.1, NM_001321113.1
NP_001308043.1, NM_001321114.1
NP_212133.1, NM_033408.3
NP_940938.1, NM_198536.2
XP_005259956.1, XM_005259899.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi131930, 48 interactors
IntActiQ6UW68, 27 interactors
MINTiQ6UW68
STRINGi9606.ENSP00000346954

Protein family/group databases

TCDBi9.A.55.1.1, the tmem205 (tmem205) family

PTM databases

iPTMnetiQ6UW68
PhosphoSitePlusiQ6UW68
SwissPalmiQ6UW68

Polymorphism and mutation databases

BioMutaiTMEM205
DMDMi74749383

Proteomic databases

EPDiQ6UW68
jPOSTiQ6UW68
MassIVEiQ6UW68
MaxQBiQ6UW68
PaxDbiQ6UW68
PeptideAtlasiQ6UW68
PRIDEiQ6UW68
ProteomicsDBi67453
TopDownProteomicsiQ6UW68

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		52091, 109 antibodies

The DNASU plasmid repository

More...DNASUi		374882

Genome annotation databases

EnsembliENST00000354882; ENSP00000346954; ENSG00000105518
ENST00000447337; ENSP00000398258; ENSG00000105518
ENST00000586590; ENSP00000466986; ENSG00000105518
ENST00000586956; ENSP00000465483; ENSG00000105518
ENST00000587948; ENSP00000465149; ENSG00000105518
ENST00000588560; ENSP00000466495; ENSG00000105518
ENST00000589555; ENSP00000465553; ENSG00000105518
ENST00000593256; ENSP00000468733; ENSG00000105518
GeneIDi374882
KEGGihsa:374882
UCSCiuc002mqz.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		374882
DisGeNETi374882
EuPathDBiHostDB:ENSG00000105518.13

GeneCards: human genes, protein and diseases

More...GeneCardsi		TMEM205
HGNCiHGNC:29631, TMEM205
HPAiENSG00000105518, Low tissue specificity
MIMi613771, gene
neXtProtiNX_Q6UW68
OpenTargetsiENSG00000105518
PharmGKBiPA162406385

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG2886, Eukaryota
GeneTreeiENSGT00390000016298
InParanoidiQ6UW68
OMAiWEASQLC
OrthoDBi1785664at2759
PhylomeDBiQ6UW68
TreeFamiTF323838

Enzyme and pathway databases

PathwayCommonsiQ6UW68

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		374882, 5 hits in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TMEM205, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		374882
PharosiQ6UW68, Tdark

Protein Ontology

More...PROi		PR:Q6UW68
RNActiQ6UW68, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000105518, Expressed in right lobe of liver and 211 other tissues
ExpressionAtlasiQ6UW68, baseline and differential
GenevisibleiQ6UW68, HS

Family and domain databases

InterProiView protein in InterPro
IPR025423, DUF4149
IPR042623, TMEM205
PANTHERiPTHR46916, PTHR46916, 1 hit
PfamiView protein in Pfam
PF13664, DUF4149, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTM205_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6UW68
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: October 7, 2020
This is version 123 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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