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Protein

KDEL motif-containing protein 1

Gene

KDELC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • glucosyltransferase activity Source: GO_Central

Protein family/group databases

Carbohydrate-Active enZymes

More...
CAZyi
GT90 Glycosyltransferase Family 90

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
KDEL motif-containing protein 1
Alternative name(s):
Endoplasmic reticulum resident protein 58
Short name:
ER protein 58
Short name:
ERp58
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KDELC1
Synonyms:EP58
ORF Names:UNQ1910/PRO4357
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 13

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000134901.12

Human Gene Nomenclature Database

More...
HGNCi
HGNC:19350 KDELC1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611613 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6UW63

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Endoplasmic reticulum

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79070

Open Targets

More...
OpenTargetsi
ENSG00000134901

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134974174

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
KDELC1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74749382

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000024716320 – 502KDEL motif-containing protein 1Add BLAST483

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi302N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi414N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6UW63

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q6UW63

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6UW63

PeptideAtlas

More...
PeptideAtlasi
Q6UW63

PRoteomics IDEntifications database

More...
PRIDEi
Q6UW63

ProteomicsDB human proteome resource

More...
ProteomicsDBi
67452

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
1430

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6UW63

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6UW63

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000134901 Expressed in 188 organ(s), highest expression level in kidney

CleanEx database of gene expression profiles

More...
CleanExi
HS_KDELC1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6UW63 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
CAB020780
HPA043946
HPA064398

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
122521, 12 interactors

Protein interaction database and analysis system

More...
IntActi
Q6UW63, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000365172

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1502
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q6UW63

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q6UW63

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q6UW63

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati24 – 130FilaminAdd BLAST107

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi499 – 502Prevents secretion from ERPROSITE-ProRule annotation4

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the KDELC family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2458 Eukaryota
ENOG410XT5U LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158318

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000286007

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG081852

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6UW63

Identification of Orthologs from Complete Genome Data

More...
OMAi
LYGPLVK

Database of Orthologous Groups

More...
OrthoDBi
EOG091G04SJ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6UW63

TreeFam database of animal gene trees

More...
TreeFami
TF323280

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR006598 LipoPS_modifying

The PANTHER Classification System

More...
PANTHERi
PTHR12203 PTHR12203, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00630 Filamin, 1 hit
PF05686 Glyco_transf_90, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00672 CAP10, 1 hit
SM00557 IG_FLMN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81296 SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00014 ER_TARGET, 1 hit
PS50194 FILAMIN_REPEAT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q6UW63-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGTLLLYCF FLATVPALAE TGGERQLSPE KSEIWGPGLK ADVVLPARYF
60 70 80 90 100
YIQAVDTSGN KFTSSPGEKV FQVKVSAPEE QFTRVGVQVL DRKDGSFIVR
110 120 130 140 150
YRMYASYKNL KVEIKFQGQH VAKSPYILKG PVYHENCDCP LQDSAAWLRE
160 170 180 190 200
MNCPETIAQI QRDLAHFPAV DPEKIAVEIP KRFGQRQSLC HYTLKDNKVY
210 220 230 240 250
IKTHGEHVGF RIFMDAILLS LTRKVKMPDV ELFVNLGDWP LEKKKSNSNI
260 270 280 290 300
HPIFSWCGST DSKDIVMPTY DLTDSVLETM GRVSLDMMSV QANTGPPWES
310 320 330 340 350
KNSTAVWRGR DSRKERLELV KLSRKHPELI DAAFTNFFFF KHDENLYGPI
360 370 380 390 400
VKHISFFDFF KHKYQINIDG TVAAYRLPYL LVGDSVVLKQ DSIYYEHFYN
410 420 430 440 450
ELQPWKHYIP VKSNLSDLLE KLKWAKDHDE EAKKIAKAGQ EFARNNLMGD
460 470 480 490 500
DIFCYYFKLF QEYANLQVSE PQIREGMKRV EPQTEDDLFP CTCHRKKTKD

EL
Length:502
Mass (Da):58,043
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i82633729E373E116
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti109N → S in BAD96287 (Ref. 2) Curated1
Sequence conflicti163D → G in BAD96287 (Ref. 2) Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_027080114I → V1 PublicationCorresponds to variant dbSNP:rs1047740Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY358959 mRNA Translation: AAQ89318.1
AK222567 mRNA Translation: BAD96287.1
AL157769 Genomic DNA No translation available.
BC001297 mRNA Translation: AAH01297.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS9504.1

NCBI Reference Sequences

More...
RefSeqi
NP_001305661.1, NM_001318732.1
NP_076994.2, NM_024089.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.408629

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000376004; ENSP00000365172; ENSG00000134901

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79070

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79070

UCSC genome browser

More...
UCSCi
uc001vpq.5 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY358959 mRNA Translation: AAQ89318.1
AK222567 mRNA Translation: BAD96287.1
AL157769 Genomic DNA No translation available.
BC001297 mRNA Translation: AAH01297.1
CCDSiCCDS9504.1
RefSeqiNP_001305661.1, NM_001318732.1
NP_076994.2, NM_024089.2
UniGeneiHs.408629

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DI7NMR-A20-130[»]
ProteinModelPortaliQ6UW63
SMRiQ6UW63
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122521, 12 interactors
IntActiQ6UW63, 1 interactor
STRINGi9606.ENSP00000365172

Protein family/group databases

CAZyiGT90 Glycosyltransferase Family 90

PTM databases

GlyConnecti1430
iPTMnetiQ6UW63
PhosphoSitePlusiQ6UW63

Polymorphism and mutation databases

BioMutaiKDELC1
DMDMi74749382

Proteomic databases

EPDiQ6UW63
MaxQBiQ6UW63
PaxDbiQ6UW63
PeptideAtlasiQ6UW63
PRIDEiQ6UW63
ProteomicsDBi67452

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
79070
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000376004; ENSP00000365172; ENSG00000134901
GeneIDi79070
KEGGihsa:79070
UCSCiuc001vpq.5 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
79070
DisGeNETi79070
EuPathDBiHostDB:ENSG00000134901.12

GeneCards: human genes, protein and diseases

More...
GeneCardsi
KDELC1
HGNCiHGNC:19350 KDELC1
HPAiCAB020780
HPA043946
HPA064398
MIMi611613 gene
neXtProtiNX_Q6UW63
OpenTargetsiENSG00000134901
PharmGKBiPA134974174

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2458 Eukaryota
ENOG410XT5U LUCA
GeneTreeiENSGT00940000158318
HOGENOMiHOG000286007
HOVERGENiHBG081852
InParanoidiQ6UW63
OMAiLYGPLVK
OrthoDBiEOG091G04SJ
PhylomeDBiQ6UW63
TreeFamiTF323280

Miscellaneous databases

EvolutionaryTraceiQ6UW63

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
79070

Protein Ontology

More...
PROi
PR:Q6UW63

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000134901 Expressed in 188 organ(s), highest expression level in kidney
CleanExiHS_KDELC1
GenevisibleiQ6UW63 HS

Family and domain databases

Gene3Di2.60.40.10, 1 hit
InterProiView protein in InterPro
IPR017868 Filamin/ABP280_repeat-like
IPR001298 Filamin/ABP280_rpt
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR006598 LipoPS_modifying
PANTHERiPTHR12203 PTHR12203, 1 hit
PfamiView protein in Pfam
PF00630 Filamin, 1 hit
PF05686 Glyco_transf_90, 1 hit
SMARTiView protein in SMART
SM00672 CAP10, 1 hit
SM00557 IG_FLMN, 1 hit
SUPFAMiSSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00014 ER_TARGET, 1 hit
PS50194 FILAMIN_REPEAT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKDEL1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6UW63
Secondary accession number(s): Q53HL3, Q9BVD2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 5, 2004
Last modified: December 5, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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