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UniProtKB - Q6U1Z4 (CMT1_CRYNJ)
Protein
Alpha-1,3-mannosyltransferase CMT1
Gene
CMT1
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Functioni
Responsible for addition of mannose residues in an alpha-1,3 linkage to a polymannosly precursor. May be involved in synthesis of capsule glucuronoxylomannan.
1 PublicationCofactori
: protein glycosylation Pathwayi
This protein is involved in the pathway protein glycosylation, which is part of Protein modification.View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.
GO - Molecular functioni
- glycosyltransferase activity Source: UniProtKB-KW
GO - Biological processi
- protein glycosylation Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Enzyme and pathway databases
UniPathwayi | UPA00378 |
Protein family/group databases
CAZyi | GT69, Glycosyltransferase Family 69 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:CMT1Imported Ordered Locus Names:CNG04090 |
Organismi | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
Taxonomic identifieri | 214684 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Cryptococcaceae › Cryptococcus › Cryptococcus neoformans species complex › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:CNG04090 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane 1 Publication; Single-pass type II membrane protein 1 Publication
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 33 | CytoplasmicSequence analysisAdd BLAST | 33 | |
Transmembranei | 34 – 54 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 55 – 466 | LumenalSequence analysisAdd BLAST | 412 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000080584 | 1 – 466 | Alpha-1,3-mannosyltransferase CMT1Add BLAST | 466 |
Proteomic databases
PaxDbi | Q6U1Z4 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 23 | DisorderedSequence analysisAdd BLAST | 23 |
Keywords - Domaini
Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QRBX, Eukaryota |
HOGENOMi | CLU_036740_0_0_1 |
InParanoidi | Q6U1Z4 |
OMAi | WNGAVAF |
OrthoDBi | 841960at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR021047, Mannosyltransferase_CMT1 |
PANTHERi | PTHR34144, PTHR34144, 1 hit |
Pfami | View protein in Pfam PF11735, CAP59_mtransfer, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6U1Z4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFRNTLRTFP RPATPSLPTS SHSPIARASL SKSPLFVLSL VLVCIFFLSF
60 70 80 90 100
LSHPDPSARK LQWPGLFPSP SPSVIHTKDL FLERALNATS EAFREICPSA
110 120 130 140 150
GDPVHLDPDL TEAQKKRYLP LKRSKRGRYL LVTNTRQIEA HLPDLLNTLI
160 170 180 190 200
VLLRYLAPEH LAVSILEGPS SDCTQKAIEQ VLKPMLDDQG LESAWTRIET
210 220 230 240 250
GESKIDWGKH NRIEKIAELR NTALAPLWQG EGDQKWEDEI EAVVFFNDVY
260 270 280 290 300
LHAADILELV YQHVKNGAGI TTAMDWWKKR PEYYYDVWVG RTIDTGDLFY
310 320 330 340 350
PIDNPWWSPS SDLFPNSPNS RNAYSRLEPF QVFSSWNALA VLSPKPFLPP
360 370 380 390 400
HNVRFRRGDV EKGECAASEC TLIATDFWKA GFGKVAVVPS VQLAYERDVA
410 420 430 440 450
KDIIEDVGKQ KEQLGWIDGV PPEHLDDKIE WSTKPPKKVR CHPWPEVNGL
460
SANVWEETRW VQPWLE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY380340 mRNA Translation: AAQ86764.1 AE017347 Genomic DNA Translation: AAW44851.1 |
RefSeqi | XP_572158.1, XM_572158.1 |
Genome annotation databases
EnsemblFungii | AAW44851; AAW44851; CNG04090 |
GeneIDi | 3258835 |
KEGGi | cne:CNG04090 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY380340 mRNA Translation: AAQ86764.1 AE017347 Genomic DNA Translation: AAW44851.1 |
RefSeqi | XP_572158.1, XM_572158.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
CAZyi | GT69, Glycosyltransferase Family 69 |
Proteomic databases
PaxDbi | Q6U1Z4 |
Genome annotation databases
EnsemblFungii | AAW44851; AAW44851; CNG04090 |
GeneIDi | 3258835 |
KEGGi | cne:CNG04090 |
Organism-specific databases
VEuPathDBi | FungiDB:CNG04090 |
Phylogenomic databases
eggNOGi | ENOG502QRBX, Eukaryota |
HOGENOMi | CLU_036740_0_0_1 |
InParanoidi | Q6U1Z4 |
OMAi | WNGAVAF |
OrthoDBi | 841960at2759 |
Enzyme and pathway databases
UniPathwayi | UPA00378 |
Family and domain databases
InterProi | View protein in InterPro IPR021047, Mannosyltransferase_CMT1 |
PANTHERi | PTHR34144, PTHR34144, 1 hit |
Pfami | View protein in Pfam PF11735, CAP59_mtransfer, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CMT1_CRYNJ | |
Accessioni | Q6U1Z4Primary (citable) accession number: Q6U1Z4 Secondary accession number(s): Q5KDG4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 27, 2004 |
Last sequence update: | July 5, 2004 | |
Last modified: | September 29, 2021 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways