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Entry version 68 (17 Jun 2020)
Sequence version 1 (05 Jul 2004)
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Protein
Submitted name:

Aec25

Gene

aec25

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Aec25Imported
Submitted name:
DewHImported
Submitted name:
EvfLImported
Submitted name:
Putative type VI secretion system proteinImported
Submitted name:
Type VI secretion system baseplate subunit TssKImported
Submitted name:
Type VI secretion system protein ImpJImported
Submitted name:
XmtHImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:aec25Imported
Synonyms:dewHImported, evfLImported, impJImported, tssKImported, xmtHImported
ORF Names:AWG78_006810Imported, C4K41_24440Imported, CT146_25965Imported, D9E13_20510Imported, DJ487_24530Imported, EA222_22855Imported, EA231_23840Imported, EA250_24740Imported, EA429_25170Imported, EYX99_16255Imported, FQU83_21600Imported, GFU47_20380Imported, GQE58_23165Imported, HmCmsJML146_00567Imported, MS8345_00225Imported, NCTC10767_04023Imported, NCTC9081_02222Imported, NCTC9434_02669Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000306171 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000233584 Componenti: Chromosome
  • UP000315141 Componenti: Chromosome
  • UP000254730 Componenti: Unassembled WGS sequence
  • UP000254647 Componenti: Unassembled WGS sequence
  • UP000413318 Componenti: Unassembled WGS sequence
  • UP000254716 Componenti: Unassembled WGS sequence
  • UP000408257 Componenti: Unassembled WGS sequence
  • UP000238807 Componenti: Unassembled WGS sequence
  • UP000429662 Componenti: Unassembled WGS sequence
  • UP000433651 Componenti: Unassembled WGS sequence
  • UP000430570 Componenti: Unassembled WGS sequence
  • UP000408798 Componenti: Unassembled WGS sequence
  • UP000076551 Componenti: Unassembled WGS sequence
  • UP000229602 Componenti: Unassembled WGS sequence
  • UP000304638 Componenti: Unassembled WGS sequence
  • UP000434743 Componenti: Unassembled WGS sequence
  • UP000323638 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105EG5 Bacteria
COG3522 LUCA

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR010263 VI_chp_4

The PANTHER Classification System

More...
PANTHERi
PTHR35566 PTHR35566, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05936 T6SS_VasE, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03353 VI_chp_4, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q6TKU3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATMKNKVIW QEGLFALPQH FQQQQRHCEY LLTRRLDALG DFFWGFTELS
60 70 80 90 100
INTELLAQGK IMIDRAAGCM PDGTVFSIPD QDLLPEPFQP GTLSSKESHN
110 120 130 140 150
IYLALPVISD VINEIQGLHS AGQGTERYRL THTRVRDFHT DEGDEQPVGL
160 170 180 190 200
GQLIPRIVSG ADDLSAMVTL PLCRILNKNA TGALVLDNTF IPTIQAVRVS
210 220 230 240 250
GLLGAFSGEV QGLLATRAAD LAGRIGSPEQ SGIADVAEFM MLQMLNRYQM
260 270 280 290 300
QFTHRSQLHT LHPEAFYRDL VGLLGELMTF TEGNRLPCTV EPYNHRDLTA
310 320 330 340 350
TFTRTVIPEL RRALNTVLVP RAQNLPLFFS EGTWIATIND PTLLQSCKLV
360 370 380 390 400
LAVRARMPYD QVQRQFIQQS KVAATDKIRS VVSVQVPGIP LHTLTAAPRQ
410 420 430 440
LPYHEGYVYF ELEKGTPAWQ DVIKAGALAL HISGSFPDLN LQLWAIRG
Length:448
Mass (Da):49,891
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC570290EF60560B9
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY395687 Genomic DNA Translation: AAQ96719.1
KF678350 Genomic DNA Translation: AHW84509.1
KF678352 Genomic DNA Translation: AHW84554.1
KM251715 Genomic DNA Translation: AIU68810.1
CP025401 Genomic DNA Translation: AUG91873.1
AAAHEN010000018 Genomic DNA Translation: EAC1992207.1
BFRA01000023 Genomic DNA Translation: GCZ96591.1
REBD01000034 Genomic DNA Translation: KAA1834136.1
RDVE01000012 Genomic DNA Translation: KAA2086413.1
RDVD01000035 Genomic DNA Translation: KAA2089987.1
RDVY01000032 Genomic DNA Translation: KAA2182398.1
WIKH01000053 Genomic DNA Translation: MQR36224.1
WSWB01000029 Genomic DNA Translation: MWE01001.1
PENJ01000028 Genomic DNA Translation: PIM20834.1
PSNQ01000034 Genomic DNA Translation: PPE25641.1
CP042246 Genomic DNA Translation: QDX38151.1
LVSP02000001 Genomic DNA Translation: RRO49277.1
UFXW01000004 Genomic DNA Translation: STC86464.1
UGCV01000008 Genomic DNA Translation: STJ16814.1
UGFV01000001 Genomic DNA Translation: STN17909.1
SSQV01000058 Genomic DNA Translation: TIJ88851.1
QFTS01000026 Genomic DNA Translation: TYD71484.1

NCBI Reference Sequences

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RefSeqi
WP_000224516.1, NZ_WJRI01000030.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ALD26662; ALD26662; AN206_20475
CRL89785; CRL89785; AL505_280018
OAO70118; OAO70118; OK10_23795

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.10853.peg.3464

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY395687 Genomic DNA Translation: AAQ96719.1
KF678350 Genomic DNA Translation: AHW84509.1
KF678352 Genomic DNA Translation: AHW84554.1
KM251715 Genomic DNA Translation: AIU68810.1
CP025401 Genomic DNA Translation: AUG91873.1
AAAHEN010000018 Genomic DNA Translation: EAC1992207.1
BFRA01000023 Genomic DNA Translation: GCZ96591.1
REBD01000034 Genomic DNA Translation: KAA1834136.1
RDVE01000012 Genomic DNA Translation: KAA2086413.1
RDVD01000035 Genomic DNA Translation: KAA2089987.1
RDVY01000032 Genomic DNA Translation: KAA2182398.1
WIKH01000053 Genomic DNA Translation: MQR36224.1
WSWB01000029 Genomic DNA Translation: MWE01001.1
PENJ01000028 Genomic DNA Translation: PIM20834.1
PSNQ01000034 Genomic DNA Translation: PPE25641.1
CP042246 Genomic DNA Translation: QDX38151.1
LVSP02000001 Genomic DNA Translation: RRO49277.1
UFXW01000004 Genomic DNA Translation: STC86464.1
UGCV01000008 Genomic DNA Translation: STJ16814.1
UGFV01000001 Genomic DNA Translation: STN17909.1
SSQV01000058 Genomic DNA Translation: TIJ88851.1
QFTS01000026 Genomic DNA Translation: TYD71484.1
RefSeqiWP_000224516.1, NZ_WJRI01000030.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiALD26662; ALD26662; AN206_20475
CRL89785; CRL89785; AL505_280018
OAO70118; OAO70118; OK10_23795
PATRICifig|562.10853.peg.3464

Phylogenomic databases

eggNOGiENOG4105EG5 Bacteria
COG3522 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR010263 VI_chp_4
PANTHERiPTHR35566 PTHR35566, 1 hit
PfamiView protein in Pfam
PF05936 T6SS_VasE, 1 hit
TIGRFAMsiTIGR03353 VI_chp_4, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ6TKU3_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6TKU3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2004
Last sequence update: July 5, 2004
Last modified: June 17, 2020
This is version 68 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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