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Entry version 115 (18 Sep 2019)
Sequence version 1 (05 Jul 2004)
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Protein

Phospholipid phosphatase-related protein type 3

Gene

PLPPR3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.1.3.4 2681

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-419408 Lysosphingolipid and LPA receptors

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Phospholipid phosphatase-related protein type 3Curated (EC:3.1.3.4)
Alternative name(s):
Lipid phosphate phosphatase-related protein type 31 Publication
PAP-2-like protein 21 Publication
Plasticity-related gene 2 protein1 Publication
Short name:
PRG-21 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PLPPR3Imported
Synonyms:LPPR31 Publication, PHP21 Publication, PRG2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23497 PLPPR3

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610391 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q6T4P5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei18 – 38HelicalSequence analysisAdd BLAST21
Transmembranei70 – 90HelicalSequence analysisAdd BLAST21
Transmembranei133 – 153HelicalSequence analysisAdd BLAST21
Transmembranei207 – 227HelicalSequence analysisAdd BLAST21
Transmembranei233 – 253HelicalSequence analysisAdd BLAST21
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000129951

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
PLPPR3

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74723394

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003175291 – 718Phospholipid phosphatase-related protein type 3Add BLAST718

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi169N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi318N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei322PhosphoserineBy similarity1
Modified residuei353PhosphoserineBy similarity1
Modified residuei376PhosphothreonineBy similarity1
Modified residuei428PhosphoserineBy similarity1
Modified residuei508PhosphoserineBy similarity1
Modified residuei641PhosphoserineBy similarity1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q6T4P5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q6T4P5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q6T4P5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q6T4P5

PeptideAtlas

More...
PeptideAtlasi
Q6T4P5

PRoteomics IDEntifications database

More...
PRIDEi
Q6T4P5

ProteomicsDB human proteome resource

More...
ProteomicsDBi
67367 [Q6T4P5-1]
67368 [Q6T4P5-2]
67369 [Q6T4P5-3]
67370 [Q6T4P5-4]

PTM databases

DEPOD human dephosphorylation database

More...
DEPODi
Q6T4P5

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q6T4P5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q6T4P5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000129951 Expressed in 84 organ(s), highest expression level in right uterine tube

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q6T4P5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q6T4P5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA052293
HPA057034

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
123019, 7 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q6T4P5

Protein interaction database and analysis system

More...
IntActi
Q6T4P5, 9 interactors

Molecular INTeraction database

More...
MINTi
Q6T4P5

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000352962

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi437 – 461Glu-richAdd BLAST25
Compositional biasi558 – 567Poly-Ser10

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410ITB3 Eukaryota
ENOG410ZZ6F LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160280

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000043094

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q6T4P5

KEGG Orthology (KO)

More...
KOi
K19582

Identification of Orthologs from Complete Genome Data

More...
OMAi
GHDSVYH

Database of Orthologous Groups

More...
OrthoDBi
1621899at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q6T4P5

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028685 LPPR3
IPR036938 P_Acid_Pase_2/haloperoxi_sf
IPR000326 P_Acid_Pase_2/haloperoxidase

The PANTHER Classification System

More...
PANTHERi
PTHR10165:SF14 PTHR10165:SF14, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01569 PAP2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00014 acidPPc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48317 SSF48317, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (4+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 4 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 4 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q6T4P5-1) [UniParc]FASTAAdd to basket
Also known as: PRG-2a

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MISTKEKNKI PKDSMTLLPC FYFVELPIVA SSIVSLYFLE LTDLFKPAKV
60 70 80 90 100
GFQCYDRTLS MPYVETNEEL IPLLMLLSLA FAAPAASIMV AEGMLYCLQS
110 120 130 140 150
RLWGRAGGPA GAEGSINAGG CNFNSFLRRT VRFVGVHVFG LCATALVTDV
160 170 180 190 200
IQLATGYHTP FFLTVCKPNY TLLGTSCEVN PYITQDICSG HDIHAILSAR
210 220 230 240 250
KTFPSQHATL SAFAAVYVSM YFNSVISDTT KLLKPILVFA FAIAAGVCGL
260 270 280 290 300
TQITQYRSHP VDVYAGFLIG AGIAAYLACH AVGNFQAPPA EKPAAPAPAK
310 320 330 340 350
DALRALTQRG HDSVYQQNKS VSTDELGPPG RLEGAPRPVA REKTSLGSLK
360 370 380 390 400
RASVDVDLLA PRSPMAKENM VTFSHTLPRA SAPSLDDPAR RHMTIHVPLD
410 420 430 440 450
ASRSKQLISE WKQKSLEGRG LGLPDDASPG HLRAPAEPMA EEEEEEEDEE
460 470 480 490 500
EEEEEEEEED EGPAPPSLYP TVQARPGLGP RVILPPRAGP PPLVHIPEEG
510 520 530 540 550
AQTGAGLSPK SGAGVRAKWL MMAEKSGAAV ANPPRLLQVI AMSKAPGAPG
560 570 580 590 600
PKAAETASSS SASSDSSQYR SPSDRDSASI VTIDAHAPHH PVVHLSAGGA
610 620 630 640 650
PWEWKAAGGG AKAEADGGYE LGDLARGFRG GAKPPGVSPG SSVSDVDQEE
660 670 680 690 700
PRFGAVATVN LATGEGLPPL GAADGALGPG SRESTLRRHA GGLGLAEREA
710
EAEAEGYFRK MQARRFPD
Length:718
Mass (Da):76,037
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8F065B5D48D2447D
GO
Isoform 2 (identifier: Q6T4P5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     134-134: V → VG

Show »
Length:719
Mass (Da):76,094
Checksum:i1624D8A4139DAE6D
GO
Isoform 3 (identifier: Q6T4P5-3) [UniParc]FASTAAdd to basket
Also known as: PRG-2b

The sequence of this isoform differs from the canonical sequence as follows:
     219-219: S → SVSPAPHCPSQALLLTRGEPSLTPTPMPQ

Show »
Length:746
Mass (Da):78,946
Checksum:i4E34F82BA0A8C472
GO
Isoform 4 (identifier: Q6T4P5-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-392: Missing.

Show »
Length:326
Mass (Da):33,787
Checksum:i8B6A6F7C76CDDD5A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0YBY4H0YBY4_HUMAN
Phospholipid phosphatase-related pr...
PLPPR3
120Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ELK5K7ELK5_HUMAN
Phospholipid phosphatase-related pr...
PLPPR3
128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0J9YW95A0A0J9YW95_HUMAN
Phospholipid phosphatase-related pr...
PLPPR3
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_038544193I → T. Corresponds to variant dbSNP:rs1540615Ensembl.1
Natural variantiVAR_038545690A → V. Corresponds to variant dbSNP:rs3746136Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0310041 – 392Missing in isoform 4. 1 PublicationAdd BLAST392
Alternative sequenceiVSP_031005134V → VG in isoform 2. 1 Publication1
Alternative sequenceiVSP_031006219S → SVSPAPHCPSQALLLTRGEP SLTPTPMPQ in isoform 3. 3 Publications1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF541282 mRNA Translation: AAP57771.1
AY436785 mRNA Translation: AAR10818.1
AF357888 mRNA Translation: AAO85401.1
AY304517 mRNA Translation: AAP72154.1
AL136596 mRNA Translation: CAB66531.1
AK021597 mRNA Translation: BAB13851.1
BC012339 mRNA Translation: AAH12339.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS12043.1 [Q6T4P5-3]
CCDS58636.1 [Q6T4P5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001257295.1, NM_001270366.1 [Q6T4P5-1]
NP_079164.1, NM_024888.2 [Q6T4P5-3]
XP_011526619.1, XM_011528317.2 [Q6T4P5-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000359894; ENSP00000352962; ENSG00000129951 [Q6T4P5-3]
ENST00000520876; ENSP00000430297; ENSG00000129951 [Q6T4P5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79948

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79948

UCSC genome browser

More...
UCSCi
uc002lpx.3 human [Q6T4P5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF541282 mRNA Translation: AAP57771.1
AY436785 mRNA Translation: AAR10818.1
AF357888 mRNA Translation: AAO85401.1
AY304517 mRNA Translation: AAP72154.1
AL136596 mRNA Translation: CAB66531.1
AK021597 mRNA Translation: BAB13851.1
BC012339 mRNA Translation: AAH12339.1
CCDSiCCDS12043.1 [Q6T4P5-3]
CCDS58636.1 [Q6T4P5-1]
RefSeqiNP_001257295.1, NM_001270366.1 [Q6T4P5-1]
NP_079164.1, NM_024888.2 [Q6T4P5-3]
XP_011526619.1, XM_011528317.2 [Q6T4P5-3]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi123019, 7 interactors
CORUMiQ6T4P5
IntActiQ6T4P5, 9 interactors
MINTiQ6T4P5
STRINGi9606.ENSP00000352962

PTM databases

DEPODiQ6T4P5
iPTMnetiQ6T4P5
PhosphoSitePlusiQ6T4P5

Polymorphism and mutation databases

BioMutaiPLPPR3
DMDMi74723394

Proteomic databases

EPDiQ6T4P5
jPOSTiQ6T4P5
MassIVEiQ6T4P5
PaxDbiQ6T4P5
PeptideAtlasiQ6T4P5
PRIDEiQ6T4P5
ProteomicsDBi67367 [Q6T4P5-1]
67368 [Q6T4P5-2]
67369 [Q6T4P5-3]
67370 [Q6T4P5-4]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000359894; ENSP00000352962; ENSG00000129951 [Q6T4P5-3]
ENST00000520876; ENSP00000430297; ENSG00000129951 [Q6T4P5-1]
GeneIDi79948
KEGGihsa:79948
UCSCiuc002lpx.3 human [Q6T4P5-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79948

GeneCards: human genes, protein and diseases

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GeneCardsi
PLPPR3
HGNCiHGNC:23497 PLPPR3
HPAiHPA052293
HPA057034
MIMi610391 gene
neXtProtiNX_Q6T4P5
OpenTargetsiENSG00000129951

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410ITB3 Eukaryota
ENOG410ZZ6F LUCA
GeneTreeiENSGT00940000160280
HOGENOMiHOG000043094
InParanoidiQ6T4P5
KOiK19582
OMAiGHDSVYH
OrthoDBi1621899at2759
PhylomeDBiQ6T4P5

Enzyme and pathway databases

BRENDAi3.1.3.4 2681
ReactomeiR-HSA-419408 Lysosphingolipid and LPA receptors

Miscellaneous databases

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79948

Pharos

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Pharosi
Q6T4P5

Protein Ontology

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PROi
PR:Q6T4P5

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000129951 Expressed in 84 organ(s), highest expression level in right uterine tube
ExpressionAtlasiQ6T4P5 baseline and differential
GenevisibleiQ6T4P5 HS

Family and domain databases

InterProiView protein in InterPro
IPR028685 LPPR3
IPR036938 P_Acid_Pase_2/haloperoxi_sf
IPR000326 P_Acid_Pase_2/haloperoxidase
PANTHERiPTHR10165:SF14 PTHR10165:SF14, 1 hit
PfamiView protein in Pfam
PF01569 PAP2, 1 hit
SMARTiView protein in SMART
SM00014 acidPPc, 1 hit
SUPFAMiSSF48317 SSF48317, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPLPR3_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6T4P5
Secondary accession number(s): Q86XQ4
, Q96EH1, Q9BQF9, Q9HAJ4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: September 18, 2019
This is version 115 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 19
    Human chromosome 19: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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