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UniProtKB - Q6SJ96 (TBPL2_HUMAN)

Entry version 129 (12 Aug 2020)
Sequence version 1 (05 Jul 2004)
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Protein

TATA box-binding protein-like 2

Gene

TBPL2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		Q6SJ96

SIGNOR Signaling Network Open Resource

More...SIGNORi		Q6SJ96

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TATA box-binding protein-like 2
Short name:
TBP-like 2
Alternative name(s):
TATA box-binding protein-related factor 3
Short name:
TBP-related factor 3
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TBPL2Imported
Synonyms:TBP2, TRF3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...EuPathDBi		HostDB:ENSG00000182521.5

Human Gene Nomenclature Database

More...HGNCi		HGNC:19841, TBPL2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		608964, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q6SJ96

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		387332

Open Targets

More...OpenTargetsi		ENSG00000182521

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134990291

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q6SJ96, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TBPL2

Domain mapping of disease mutations (DMDM)

More...DMDMi		74749326

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003181181 – 375TATA box-binding protein-like 2Add BLAST375

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q6SJ96

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		Q6SJ96

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q6SJ96

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q6SJ96

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q6SJ96

PeptideAtlas

More...PeptideAtlasi		Q6SJ96

PRoteomics IDEntifications database

More...PRIDEi		Q6SJ96

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		67358

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q6SJ96

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q6SJ96

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.2 Publications

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000182521, Expressed in sural nerve and 26 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q6SJ96, baseline and differential

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000182521, Tissue enhanced (skeletal)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with TAF3.

By similarity

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		132286, 10 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000247219

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q6SJ96, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q6SJ96

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi22 – 26Poly-ProSequence analysis5

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TBP family.Sequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3302, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000159561

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_060161_1_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q6SJ96

KEGG Orthology (KO)

More...KOi		K03120

Identification of Orthologs from Complete Genome Data

More...OMAi		MEQEETY

Database of Orthologous Groups

More...OrthoDBi		1219067at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q6SJ96

TreeFam database of animal gene trees

More...TreeFami		TF300102

Family and domain databases

Conserved Domains Database

More...CDDi		cd04516, TBP_eukaryotes, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.310.10, 2 hits

HAMAP database of protein families

More...HAMAPi		MF_00408, TATA_bind_prot_arch, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000814, TBP
IPR030491, TBP_CS
IPR012295, TBP_dom_sf
IPR033710, TBP_eukaryotic

The PANTHER Classification System

More...PANTHERi		PTHR10126, PTHR10126, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00352, TBP, 2 hits

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00686, TIFACTORIID

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00351, TFIID, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q6SJ96-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASAPWPERV PRLLAPRLPS YPPPPPTVGL RSMEQEETYL ELYLDQCAAQ 
        60         70         80         90        100
DGLAPPRSPL FSPVVPYDMY ILNASNPDTA FNSNPEVKET SGDFSSVDLS 
       110        120        130        140        150
FLPDEVTQEN KDQPVISKHE TEENSESQSP QSRLPSPSEQ DVGLGLNSSS 
       160        170        180        190        200
LSNSHSQLHP GDTDSVQPSP EKPNSDSLSL ASITPMTPMT PISECCGIVP 
       210        220        230        240        250
QLQNIVSTVN LACKLDLKKI ALHAKNAEYN PKRFAAVIMR IREPRTTALI 
       260        270        280        290        300
FSSGKMVCTG AKSEEQSRLA ARKYARVVQK LGFPARFLDF KIQNMVGSCD 
       310        320        330        340        350
VRFPIRLEGL VLTHQQFSSY EPELFPGLIY RMVKPRIVLL IFVSGKVVLT 
       360        370 
GAKERSEIYE AFENIYPILK GFKKA
Length:375
Mass (Da):41,524
Last modified:July 5, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE55539A49FE76704
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3V454G3V454_HUMAN
TATA box-binding protein-like prote...
TBPL2
22Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_03869231R → P1 PublicationCorresponds to variant dbSNP:rs8019270Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AY457923 mRNA Translation: AAR24281.1
DQ448593 mRNA Translation: ABD93323.1
BC117159 mRNA Translation: AAI17160.1
BC117185 mRNA Translation: AAI17186.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS9724.1

NCBI Reference Sequences

More...RefSeqi		NP_950248.1, NM_199047.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000247219; ENSP00000247219; ENSG00000182521

Database of genes from NCBI RefSeq genomes

More...GeneIDi		387332

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:387332

UCSC genome browser

More...UCSCi		uc001xby.5, human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY457923 mRNA Translation: AAR24281.1
DQ448593 mRNA Translation: ABD93323.1
BC117159 mRNA Translation: AAI17160.1
BC117185 mRNA Translation: AAI17186.1
CCDSiCCDS9724.1
RefSeqiNP_950248.1, NM_199047.2

3D structure databases

SMRiQ6SJ96
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi132286, 10 interactors
STRINGi9606.ENSP00000247219

PTM databases

iPTMnetiQ6SJ96
PhosphoSitePlusiQ6SJ96

Polymorphism and mutation databases

BioMutaiTBPL2
DMDMi74749326

Proteomic databases

EPDiQ6SJ96
jPOSTiQ6SJ96
MassIVEiQ6SJ96
MaxQBiQ6SJ96
PaxDbiQ6SJ96
PeptideAtlasiQ6SJ96
PRIDEiQ6SJ96
ProteomicsDBi67358

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		61077, 117 antibodies

The DNASU plasmid repository

More...DNASUi		387332

Genome annotation databases

EnsembliENST00000247219; ENSP00000247219; ENSG00000182521
GeneIDi387332
KEGGihsa:387332
UCSCiuc001xby.5, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		387332
DisGeNETi387332
EuPathDBiHostDB:ENSG00000182521.5

GeneCards: human genes, protein and diseases

More...GeneCardsi		TBPL2
HGNCiHGNC:19841, TBPL2
HPAiENSG00000182521, Tissue enhanced (skeletal)
MIMi608964, gene
neXtProtiNX_Q6SJ96
OpenTargetsiENSG00000182521
PharmGKBiPA134990291

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG3302, Eukaryota
GeneTreeiENSGT00940000159561
HOGENOMiCLU_060161_1_2_1
InParanoidiQ6SJ96
KOiK03120
OMAiMEQEETY
OrthoDBi1219067at2759
PhylomeDBiQ6SJ96
TreeFamiTF300102

Enzyme and pathway databases

PathwayCommonsiQ6SJ96
SIGNORiQ6SJ96

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		387332, 6 hits in 868 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TBPL2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		387332
PharosiQ6SJ96, Tbio

Protein Ontology

More...PROi		PR:Q6SJ96
RNActiQ6SJ96, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000182521, Expressed in sural nerve and 26 other tissues
ExpressionAtlasiQ6SJ96, baseline and differential

Family and domain databases

CDDicd04516, TBP_eukaryotes, 1 hit
Gene3Di3.30.310.10, 2 hits
HAMAPiMF_00408, TATA_bind_prot_arch, 1 hit
InterProiView protein in InterPro
IPR000814, TBP
IPR030491, TBP_CS
IPR012295, TBP_dom_sf
IPR033710, TBP_eukaryotic
PANTHERiPTHR10126, PTHR10126, 1 hit
PfamiView protein in Pfam
PF00352, TBP, 2 hits
PRINTSiPR00686, TIFACTORIID
PROSITEiView protein in PROSITE
PS00351, TFIID, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTBPL2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q6SJ96
Secondary accession number(s): Q17RU8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: July 5, 2004
Last modified: August 12, 2020
This is version 129 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families
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