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Protein

Transcription initiation factor TFIID subunit 5

Gene

TAF5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

TAFs are components of the transcription factor IID (TFIID) complex that is essential for mediating regulation of RNA polymerase transcription.By similarity

GO - Biological processi

Keywordsi

Molecular functionActivator
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-ATH-674695 RNA Polymerase II Pre-transcription Events
R-ATH-73776 RNA Polymerase II Promoter Escape
R-ATH-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
R-ATH-75953 RNA Polymerase II Transcription Initiation
R-ATH-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription initiation factor TFIID subunit 5
Alternative name(s):
TBP-associated factor 5
Short name:
AtTAF5
Gene namesi
Name:TAF5
Ordered Locus Names:At5g25150
ORF Names:F21J6
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G25150
TAIRilocus:2179300 AT5G25150

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004240381 – 669Transcription initiation factor TFIID subunit 5Add BLAST669

Proteomic databases

PaxDbiQ6S7B0
PRIDEiQ6S7B0

PTM databases

iPTMnetiQ6S7B0

Expressioni

Tissue specificityi

Expressed in roots, leaves and inflorescences.1 Publication

Gene expression databases

ExpressionAtlasiQ6S7B0 baseline and differential
GenevisibleiQ6S7B0 AT

Interactioni

Subunit structurei

Component of the TFIID complexe. TFIID is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs) whose MWs range from 14-217 kDa. May homodimerize to form the scaffold for the complex. Interacts with TAF4, TAF4B, TAF6B, TAF8, TAF9, TAF12B, TAF14 and TAF15B.1 Publication

Binary interactionsi

WithEntry#Exp.IntActNotes
TAF6BF4HVA63EBI-1247501,EBI-1245557

Protein-protein interaction databases

BioGridi17861, 11 interactors
IntActiQ6S7B0, 12 interactors
STRINGi3702.AT5G25150.1

Structurei

3D structure databases

ProteinModelPortaliQ6S7B0
SMRiQ6S7B0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati350 – 389WD 1Add BLAST40
Repeati416 – 455WD 2Add BLAST40
Repeati458 – 497WD 3Add BLAST40
Repeati500 – 541WD 4Add BLAST42
Repeati543 – 581WD 5Add BLAST39
Repeati584 – 623WD 6Add BLAST40

Sequence similaritiesi

Belongs to the TAF5 family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG0263 Eukaryota
ENOG410XPM5 LUCA
HOGENOMiHOG000212424
InParanoidiQ6S7B0
KOiK03130
OMAiDCVQFHP
OrthoDBiEOG0936047O
PhylomeDBiQ6S7B0

Family and domain databases

CDDicd08044 TAF5_NTD2, 1 hit
Gene3Di1.25.40.500, 1 hit
2.130.10.10, 3 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR007582 TFIID_NTD2
IPR037264 TFIID_NTD2_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF04494 TFIID_NTD2, 1 hit
PF00400 WD40, 6 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00320 WD40, 6 hits
SUPFAMiSSF160897 SSF160897, 1 hit
SSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 4 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.iShow all

Q6S7B0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDPEQINEFV VGYLKKKGFS SAAKDLESYH HQNNNGSSFT SVDYHNDPEL
60 70 80 90 100
TKLIRSFSQQ EDDPTRYREG YSKLRSWAYN SLDLYKHELL RVMYPVFIHC
110 120 130 140 150
YMDLVGKGHT QEARAFFNSF RKDHEMVHLR DLQKLEGVLS PSHLEEMEFA
160 170 180 190 200
RSLRKSKVNI KFCQYSYELL LQYLHSTVST LMLGIINEHI NFQVYSGQPT
210 220 230 240 250
SSSDDIEAVT IVGSFQDTAN HINQKEIQWG LLEDSLEDRL EKTGGLLSDS
260 270 280 290 300
EKGQGESKDG DADDSKKRST EIGKQGSSLK KLKKDKAGNA TAKVARLETI
310 320 330 340 350
TVSPAPRVKP ELALPVMSTD VEQSILEDLR NRVQLSSVAM PSVSFYTFVN
360 370 380 390 400
THNGLNCSSI SHDGSLVAGG FSDSSIKVWD MAKIGQAGSG ALQAENDSSD
410 420 430 440 450
QSIGPNGRRS YTLLLGHSGP VYSATFSPPG DFVLSSSADT TIRLWSTKLN
460 470 480 490 500
ANLVCYKGHN YPVWDAQFSP FGHYFASCSH DRTARIWSMD RIQPLRIMAG
510 520 530 540 550
HLSDVDCVQW HPNCNYIATG SSDKTVRLWD VQTGECVRIF IGHRSMVLSL
560 570 580 590 600
AMSPDGRYMA SGDEDGTIMM WDLSTARCIT PLMGHNSCVW SLSYSGEGSL
610 620 630 640 650
LASGSADCTV KLWDVTSSTK LTKAEEKNGN SNRLRSLRTF PTKSTPVHAL
660
RFSRRNLLFA AGAISKPAN
Length:669
Mass (Da):74,414
Last modified:July 5, 2004 - v1
Checksum:i0CFC6ED981CD85C7
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1P8BA79A0A1P8BA79_ARATH
TBP-associated factor 5
TAF5 TBP-associated factor 5, At5g25150, F21J6.5
665Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY463620 mRNA Translation: AAR28022.1
AC006259 Genomic DNA No translation available.
CP002688 Genomic DNA Translation: AED93406.1
RefSeqiNP_197897.3, NM_122424.4
UniGeneiAt.43447

Genome annotation databases

EnsemblPlantsiAT5G25150.1; AT5G25150.1; AT5G25150
GeneIDi832586
GrameneiAT5G25150.1; AT5G25150.1; AT5G25150
KEGGiath:AT5G25150

Similar proteinsi

Entry informationi

Entry nameiTAF5_ARATH
AccessioniPrimary (citable) accession number: Q6S7B0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 16, 2013
Last sequence update: July 5, 2004
Last modified: May 23, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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