UniProtKB - Q6S5I3 (S115A_MOUSE)
Protein
Protein S100-A15A
Gene
S100a15a
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Calcium bindingi | 66 – 77 | 1; high affinityPROSITE-ProRule annotationAdd BLAST | 12 |
GO - Molecular functioni
- calcium-dependent protein binding Source: GO_Central
- calcium ion binding Source: GO_Central
- chemoattractant activity Source: MGI
- protein self-association Source: MGI
- transition metal ion binding Source: InterPro
GO - Biological processi
- inflammatory response Source: MGI
Keywordsi
Ligand | Calcium, Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Protein S100-A15AAlternative name(s): Protein S100-A7A S100 calcium-binding protein A15A S100 calcium-binding protein A7A |
Gene namesi | Name:S100a15a Synonyms:S100a15, S100a7, S100a7a |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2687194, S100a7a |
Subcellular locationi
Extracellular region or secreted
- extracellular space Source: MGI
Other locations
- cytoplasm Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000320087 | 1 – 108 | Protein S100-A15AAdd BLAST | 108 |
Proteomic databases
PaxDbi | Q6S5I3 |
PRIDEi | Q6S5I3 |
ProteomicsDBi | 255436 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000063767, Expressed in esophagus and 42 other tissues |
Interactioni
GO - Molecular functioni
- calcium-dependent protein binding Source: GO_Central
- chemoattractant activity Source: MGI
- protein self-association Source: MGI
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000078268 |
Miscellaneous databases
RNActi | Q6S5I3, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 53 – 88 | EF-handPROSITE-ProRule annotationAdd BLAST | 36 |
Sequence similaritiesi
Belongs to the S-100 family.Curated
Phylogenomic databases
eggNOGi | ENOG502SXYF, Eukaryota |
GeneTreei | ENSGT00910000144375 |
HOGENOMi | CLU_138624_5_0_1 |
InParanoidi | Q6S5I3 |
OMAi | FQIIHCF |
OrthoDBi | 1486203at2759 |
PhylomeDBi | Q6S5I3 |
TreeFami | TF341148 |
Family and domain databases
CDDi | cd00213, S-100, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR034325, S-100_dom IPR013787, S100_Ca-bd_sub IPR028495, S100A15A |
PANTHERi | PTHR11639:SF29, PTHR11639:SF29, 1 hit |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit PF01023, S_100, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 1 hit SM01394, S_100, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q6S5I3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPDTPVEDSL FQIIHCFHHY AAREGDKETL SLEELKALLL DSVPRFMDTL
60 70 80 90 100
GRRQPYYITE LFRAADKNKD NQICFDEFLY ILGKLVKDYH LQFHRQLCAH
YCTEHSLY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY465109 mRNA Translation: AAR32782.1 AY465110 Genomic DNA Translation: AAR32783.1 AY582964 mRNA Translation: AAS91715.1 BC107307 mRNA Translation: AAI07308.1 BC107308 mRNA Translation: AAI07309.1 |
CCDSi | CCDS17541.1 |
RefSeqi | NP_955454.1, NM_199422.1 XP_006501695.1, XM_006501632.3 XP_006501696.1, XM_006501633.3 XP_006501698.1, XM_006501635.3 |
Genome annotation databases
Ensembli | ENSMUST00000079286; ENSMUSP00000078268; ENSMUSG00000063767 |
GeneIDi | 381493 |
KEGGi | mmu:381493 |
UCSCi | uc008qdc.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY465109 mRNA Translation: AAR32782.1 AY465110 Genomic DNA Translation: AAR32783.1 AY582964 mRNA Translation: AAS91715.1 BC107307 mRNA Translation: AAI07308.1 BC107308 mRNA Translation: AAI07309.1 |
CCDSi | CCDS17541.1 |
RefSeqi | NP_955454.1, NM_199422.1 XP_006501695.1, XM_006501632.3 XP_006501696.1, XM_006501633.3 XP_006501698.1, XM_006501635.3 |
3D structure databases
SMRi | Q6S5I3 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000078268 |
Proteomic databases
PaxDbi | Q6S5I3 |
PRIDEi | Q6S5I3 |
ProteomicsDBi | 255436 |
Genome annotation databases
Ensembli | ENSMUST00000079286; ENSMUSP00000078268; ENSMUSG00000063767 |
GeneIDi | 381493 |
KEGGi | mmu:381493 |
UCSCi | uc008qdc.1, mouse |
Organism-specific databases
CTDi | 338324 |
MGIi | MGI:2687194, S100a7a |
Phylogenomic databases
eggNOGi | ENOG502SXYF, Eukaryota |
GeneTreei | ENSGT00910000144375 |
HOGENOMi | CLU_138624_5_0_1 |
InParanoidi | Q6S5I3 |
OMAi | FQIIHCF |
OrthoDBi | 1486203at2759 |
PhylomeDBi | Q6S5I3 |
TreeFami | TF341148 |
Miscellaneous databases
BioGRID-ORCSi | 381493, 0 hits in 52 CRISPR screens |
PROi | PR:Q6S5I3 |
RNActi | Q6S5I3, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000063767, Expressed in esophagus and 42 other tissues |
Family and domain databases
CDDi | cd00213, S-100, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR018247, EF_Hand_1_Ca_BS IPR002048, EF_hand_dom IPR034325, S-100_dom IPR013787, S100_Ca-bd_sub IPR028495, S100A15A |
PANTHERi | PTHR11639:SF29, PTHR11639:SF29, 1 hit |
Pfami | View protein in Pfam PF00036, EF-hand_1, 1 hit PF01023, S_100, 1 hit |
SMARTi | View protein in SMART SM00054, EFh, 1 hit SM01394, S_100, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit |
PROSITEi | View protein in PROSITE PS00018, EF_HAND_1, 1 hit PS50222, EF_HAND_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | S115A_MOUSE | |
Accessioni | Q6S5I3Primary (citable) accession number: Q6S5I3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 26, 2008 |
Last sequence update: | July 5, 2004 | |
Last modified: | April 7, 2021 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families